4U4VA

Structure of a nitrate/nitrite antiporter nark in apo inward-open state
Total Genus 180
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
180
sequence length
451
structure length
442
Chain Sequence
AVITDWRPEDPAFWQQRGQRIASRNLWISVPCLLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGRRWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPKQKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWIWVPFLAIFTIAAWFGMNDLATLPVLKRGHLWIMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGLLFLTLPTDQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSDERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACVVITWAVYGRHSKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
source organism Escherichia coli str. k-12 substr. mg1655
publication title Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK
pubmed doi rcsb
molecule keywords Nitrate/nitrite transporter NarK
total genus 180
structure length 442
sequence length 451
ec nomenclature
pdb deposition date 2014-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07690 MFS_1 Major Facilitator Superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4u4vA01
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4u4vA02
4GBZA 4IU9A 4TPHA 4D2CA 5A2NA 4J05A 4TPGA 3WDOA 5D58A 2V8NA 4JREA 4IU8A 3O7PA 5D59A 4D2DA 4U4TA 4IKYA 4QIQA 2CFQA 4GC0A 4UVMA 4IKZA 4YBQA 4TPJA 4ZWCA 4ZW9A 5EQHA 3O7QA 2Y5YA 4LEPA 5C65A 4ZWBA 4YB9D 4XNJA 4OH3A 5EQGA 4D2BA 5A2OA 4W6VA 5GXBA 4IKXA 4JA3A 1PW4A 4JR9A 4LDSA 4U4VA 5EQIA 2CFPA 4IKWA 4IKVA 1PV6A 4PYPA 4APSA 4ZYRA 2XUTA 4GBYA 4OAAA 1PV7A 4U4WA 4XNIA 4Q65A 5D6KA
chains in the Genus database with same CATH superfamily
4NI9A 3QB7A 3DI3A 4A3CD 1N1FA 4A3GD 5IYDD 4IU8A 3Q1SI 4UVMA 3I4ND 3IRHA 3WCYI 3QB1A 2O27A 1M48A 4I77Z 3DGCL 2INTA 5D70A 3SE4B 5IYCD 5D6KA 3AYHA 2Q7NB 5A2NA 4DKEA 2KZ1A 1PY2A 3G9VB 1WCMD 5D59A 1ITIA 4TPJA 4IKZA 1M4AA 4ZWCA 1FG9A 4BY1D 5A2OA 1M4RA 1V7NV 1PV6A 1INRA 1HWGA 1M47A 1PV7A 3L5WI 2D48A 3DI2A 4D2CA 4TPGA 1ILKA 2B8ZA 2V8NA 1ALUA 4BY7D 4YUEC 3BPNA 4QIQA 4YBQA 3NCCA 3UF2A 1CSGA 5E4EA 1A7MA 3B5KA 3HHCA 2PSMA 1IL6A 1HUWA 1M49A 3HHRA 2B8YA 1ITFA 3O7QA 2Y5YA 2ILKA 1Y6NL 1BGCA 4W6VA 5GXBA 3G6DA 4RS1A 2XUTA 2VUMD 1Y6ML 5C44D 4IKYA 4LEPA 5C65A 3H3VE 4YQXA 5TS9A 5D22A 4GS7A 5FHXA 3HOVD 2C35A 4Q65A 3QWRB 1HULA 4D2DA 4Z5RD 2CFQA 1A22A 4MHLA 4EXNA 1PGRA 5EQHA 3H0GD 3BPOA 2O6IA 4BBRD 5FLMD 4A3KD 2R93D 1IK0A 4OAAA 1B5LA 1J7VL 2XQBA 2Q98A 3BPLA 1PW6A 4DOHA 1AXIA 2JA5D 4GC0A 4IKXA 4JA3A 1PW4A 4JR9A 1EKUA 5EQIA 2Q14A 4YPGC 1EERA 1AX8A 3D85C 1HIJA 1Y1VD 4NI7A 5L6YC 4WRLB 5IP9D 2JA8D 5LQBA 3S9DA 2O26A 3FKID 4CNIC 4YB9D 2GMFA 5EQGA 3LB6A 4U4VA 1BBNA 5D71A 3SE3B 1HZIA 4GBYA 2ERJD 2B8UA 3VA2A 1WU3I 1CYLA 4J05A 4DKCA 1D9GA 3UF5A 4ZS7A 4O9HA 3NCBA 4PS4A 3QAZA 4PYPA 1SCFA 3NPZA 3N0PA 2B63D 4A3ED 3HOWD 4X51A 3D87A 1VLKA 4A3FD 3OG4A 3MZGA 3PIWA 4NN5A 3NCFA 1NBPA 4XNIA 3I4MD 1FYHA 4NN6A 1M4CA 3WDOA 1JLIA 3O7PA 3PO3D 1HGUA 4NEMA 1HIKA 4NEJA 3NCEA 4ZF7A 4GRWA 3LB6B 5C3ED 3EJJA 3PO2D 2H24A 1BUYA 4A93D 4J4LC 2B8XA 4JREA 1QVNA 1BP3A 1Z7CA 3HOZD 2L3OA 3DUHC 5C7XA 2JA7D 3QT2C 2B91A 1RHGA 3HOUD 2D9QA 1PVHB 2E9WC 2Z3RA 4NN7A 1IRLA 4GBZA 4IU9A 5C4XD 3OQ3A 1LK3A 5D58A 1YKBA 1AU1A 4U4TA 4EXPA 2IL6A 3HMXB 4A3BD 1M4BA 1BGDA 2Z3QA 3BESL 1D9CA 5IYBD 1EMRA 4OH3A 1F6FA 3PIVA 1IARA 1RCBA 4LDSA 4NKQC 3UEZE 4A3DD 4IKWA 4ZYRA 2B5IA 1KF9A 3N06A 4FA8E 3DLQI 2L3YA 1GNCA 4TPHA 1LKIA 3EW3A 3HOYD 2LAGA 1CD9A 2R92D 2OQPA 1CNT1 5D72A 1F45B 4XNJA 3L5XA 4DKFA 4DKDA 4A3LD 4YDYI 1V7MV 2CFPA 1ITLA 1LQSL 1HWHA 4A3ID 2CYKA 1Z92A 1ITMA 4A3JD 2JA6D 1I1RB 1GA3A 1RFBA 1CN4C 4LRLA 1BGEA 2LMSA 2B90A 1Y6KL 4BBSD 3D48P 1Y14A 3OG6A 1EXZA 1P9MB 2HYMB 5IP7D 4BXXD 1Y1WD 1ETEA 5D28B 3TGXB 4O6KA 1RW5A 3HOXD 3INKC 4ZW9A 4ZWBA 5KNHI 3UX9A 4D2BA 4IKVA 5FUCA 4APSA 1IJZA 4U4WA 1BCNA 2R7ZD 1EVSA 4A3MD
chains in the Genus database with same CATH topology
4GBZA 4IU9A 4TPHA 4D2CA 5A2NA 4J05A 4TPGA 3WDOA 5D58A 2V8NA 4JREA 4IU8A 3O7PA 5D59A 4D2DA 4U4TA 4IKYA 4QIQA 2CFQA 4GC0A 4UVMA 4IKZA 4YBQA 4TPJA 4ZWCA 4ZW9A 5EQHA 3O7QA 2Y5YA 4LEPA 5C65A 4ZWBA 4YB9D 4XNJA 4OH3A 5EQGA 4D2BA 5A2OA 4W6VA 5GXBA 4IKXA 4JA3A 1PW4A 4JR9A 4LDSA 4U4VA 5EQIA 2CFPA 4IKWA 4IKVA 1PV6A 4PYPA 4APSA 4ZYRA 2XUTA 4GBYA 4OAAA 1PV7A 4U4WA 4XNIA 4Q65A 5D6KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GBZ A;  4IU9 A;  4TPH A;  4D2C A;  5A2N A;  4J05 A;  4TPG A;  3WDO A;  5D58 A;  2V8N A;  4JRE A;  4IU8 A;  3O7P A;  5D59 A;  4D2D A;  4U4T A;  4IKY A;  4QIQ A;  2CFQ A;  4GC0 A;  4UVM A;  4IKZ A;  4YBQ A;  4TPJ A;  4ZWC A;  4ZW9 A;  5EQH A;  3O7Q A;  2Y5Y A;  4LEP A;  5C65 A;  4ZWB A;  4YB9 D;  4XNJ A;  4OH3 A;  5EQG A;  4D2B A;  5A2O A;  4W6V A;  5GXB A;  4IKX A;  4JA3 A;  1PW4 A;  4JR9 A;  4LDS A;  4U4V A;  5EQI A;  2CFP A;  4IKW A;  4IKV A;  1PV6 A;  4PYP A;  4APS A;  4ZYR A;  2XUT A;  4GBY A;  4OAA A;  1PV7 A;  4U4W A;  4XNI A;  4Q65 A;  5D6K A; 
#chains in the Genus database with same CATH topology
 4NI9 A;  3QB7 A;  3DI3 A;  4A3C D;  1N1F A;  4A3G D;  5IYD D;  4IU8 A;  3Q1S I;  4UVM A;  3I4N D;  3IRH A;  3WCY I;  3QB1 A;  2O27 A;  1M48 A;  4I77 Z;  3DGC L;  2INT A;  5D70 A;  3SE4 B;  5IYC D;  5D6K A;  3AYH A;  2Q7N B;  5A2N A;  4DKE A;  2KZ1 A;  1PY2 A;  3G9V B;  1WCM D;  5D59 A;  1ITI A;  4TPJ A;  4IKZ A;  1M4A A;  4ZWC A;  1FG9 A;  4BY1 D;  5A2O A;  1M4R A;  1V7N V;  1PV6 A;  1INR A;  1HWG A;  1M47 A;  1PV7 A;  3L5W I;  2D48 A;  3DI2 A;  4D2C A;  4TPG A;  1ILK A;  2B8Z A;  2V8N A;  1ALU A;  4BY7 D;  4YUE C;  3BPN A;  4QIQ A;  4YBQ A;  3NCC A;  3UF2 A;  1CSG A;  5E4E A;  1A7M A;  3B5K A;  3HHC A;  2PSM A;  1IL6 A;  1HUW A;  1M49 A;  3HHR A;  2B8Y A;  1ITF A;  3O7Q A;  2Y5Y A;  2ILK A;  1Y6N L;  1BGC A;  4W6V A;  5GXB A;  3G6D A;  4RS1 A;  2XUT A;  2VUM D;  1Y6M L;  5C44 D;  4IKY A;  4LEP A;  5C65 A;  3H3V E;  4YQX A;  5TS9 A;  5D22 A;  4GS7 A;  5FHX A;  3HOV D;  2C35 A;  4Q65 A;  3QWR B;  1HUL A;  4D2D A;  4Z5R D;  2CFQ A;  1A22 A;  4MHL A;  4EXN A;  1PGR A;  5EQH A;  3H0G D;  3BPO A;  2O6I A;  4BBR D;  5FLM D;  4A3K D;  2R93 D;  1IK0 A;  4OAA A;  1B5L A;  1J7V L;  2XQB A;  2Q98 A;  3BPL A;  1PW6 A;  4DOH A;  1AXI A;  2JA5 D;  4GC0 A;  4IKX A;  4JA3 A;  1PW4 A;  4JR9 A;  1EKU A;  5EQI A;  2Q14 A;  4YPG C;  1EER A;  1AX8 A;  3D85 C;  1HIJ A;  1Y1V D;  4NI7 A;  5L6Y C;  4WRL B;  5IP9 D;  2JA8 D;  5LQB A;  3S9D A;  2O26 A;  3FKI D;  4CNI C;  4YB9 D;  2GMF A;  5EQG A;  3LB6 A;  4U4V A;  1BBN A;  5D71 A;  3SE3 B;  1HZI A;  4GBY A;  2ERJ D;  2B8U A;  3VA2 A;  1WU3 I;  1CYL A;  4J05 A;  4DKC A;  1D9G A;  3UF5 A;  4ZS7 A;  4O9H A;  3NCB A;  4PS4 A;  3QAZ A;  4PYP A;  1SCF A;  3NPZ A;  3N0P A;  2B63 D;  4A3E D;  3HOW D;  4X51 A;  3D87 A;  1VLK A;  4A3F D;  3OG4 A;  3MZG A;  3PIW A;  4NN5 A;  3NCF A;  1NBP A;  4XNI A;  3I4M D;  1FYH A;  4NN6 A;  1M4C A;  3WDO A;  1JLI A;  3O7P A;  3PO3 D;  1HGU A;  4NEM A;  1HIK A;  4NEJ A;  3NCE A;  4ZF7 A;  4GRW A;  3LB6 B;  5C3E D;  3EJJ A;  3PO2 D;  2H24 A;  1BUY A;  4A93 D;  4J4L C;  2B8X A;  4JRE A;  1QVN A;  1BP3 A;  1Z7C A;  3HOZ D;  2L3O A;  3DUH C;  5C7X A;  2JA7 D;  3QT2 C;  2B91 A;  1RHG A;  3HOU D;  2D9Q A;  1PVH B;  2E9W C;  2Z3R A;  4NN7 A;  1IRL A;  4GBZ A;  4IU9 A;  5C4X D;  3OQ3 A;  1LK3 A;  5D58 A;  1YKB A;  1AU1 A;  4U4T A;  4EXP A;  2IL6 A;  3HMX B;  4A3B D;  1M4B A;  1BGD A;  2Z3Q A;  3BES L;  1D9C A;  5IYB D;  1EMR A;  4OH3 A;  1F6F A;  3PIV A;  1IAR A;  1RCB A;  4LDS A;  4NKQ C;  3UEZ E;  4A3D D;  4IKW A;  4ZYR A;  2B5I A;  1KF9 A;  3N06 A;  4FA8 E;  3DLQ I;  2L3Y A;  1GNC A;  4TPH A;  1LKI A;  3EW3 A;  3HOY D;  2LAG A;  1CD9 A;  2R92 D;  2OQP A;  1CNT 1;  5D72 A;  1F45 B;  4XNJ A;  3L5X A;  4DKF A;  4DKD A;  4A3L D;  4YDY I;  1V7M V;  2CFP A;  1ITL A;  1LQS L;  1HWH A;  4A3I D;  2CYK A;  1Z92 A;  1ITM A;  4A3J D;  2JA6 D;  1I1R B;  1GA3 A;  1RFB A;  1CN4 C;  4LRL A;  1BGE A;  2LMS A;  2B90 A;  1Y6K L;  4BBS D;  3D48 P;  1Y14 A;  3OG6 A;  1EXZ A;  1P9M B;  2HYM B;  5IP7 D;  4BXX D;  1Y1W D;  1ETE A;  5D28 B;  3TGX B;  4O6K A;  1RW5 A;  3HOX D;  3INK C;  4ZW9 A;  4ZWB A;  5KNH I;  3UX9 A;  4D2B A;  4IKV A;  5FUC A;  4APS A;  1IJZ A;  4U4W A;  1BCN A;  2R7Z D;  1EVS A;  4A3M D; 
#chains in the Genus database with same CATH homology
 4GBZ A;  4IU9 A;  4TPH A;  4D2C A;  5A2N A;  4J05 A;  4TPG A;  3WDO A;  5D58 A;  2V8N A;  4JRE A;  4IU8 A;  3O7P A;  5D59 A;  4D2D A;  4U4T A;  4IKY A;  4QIQ A;  2CFQ A;  4GC0 A;  4UVM A;  4IKZ A;  4YBQ A;  4TPJ A;  4ZWC A;  4ZW9 A;  5EQH A;  3O7Q A;  2Y5Y A;  4LEP A;  5C65 A;  4ZWB A;  4YB9 D;  4XNJ A;  4OH3 A;  5EQG A;  4D2B A;  5A2O A;  4W6V A;  5GXB A;  4IKX A;  4JA3 A;  1PW4 A;  4JR9 A;  4LDS A;  4U4V A;  5EQI A;  2CFP A;  4IKW A;  4IKV A;  1PV6 A;  4PYP A;  4APS A;  4ZYR A;  2XUT A;  4GBY A;  4OAA A;  1PV7 A;  4U4W A;  4XNI A;  4Q65 A;  5D6K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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