4ZW9A

Crystal structure of human glut3 bound to d-glucose in the outward-occluded conformation at 1.5 angstrom
Total Genus 224
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
470
structure length
470
Chain Sequence
MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFITKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of ligand recognition and transport by glucose transporters
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Solute carrier family 2, facilitated glucose transporter mem
total genus 224
structure length 470
sequence length 470
ec nomenclature
pdb deposition date 2015-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4zw9A00
2CFQA 1PV7A 4IU9A 4IKWA 5EQGA 5A2OA 4APSA 4PYPA 5EQHA 4Q65A 4W6VA 2CFPA 4IU8A 4OH3A 4ZYRA 4U4VA 3WDOA 4XNIA 2V8NA 4J05A 4YBQA 5C65A 4IKYA 2Y5YA 4GC0A 4YB9D 4IKXA 1PV6A 4IKZA 5D6KA 2XUTA 4JREA 4TPJA 4XNJA 4TPGA 4D2BA 4GBYA 5EQIA 1PW4A 5GXBA 4D2DA 4LDSA 4U4WA 4U4TA 4ZWCA 5A2NA 4TPHA 4ZWBA 4OAAA 4UVMA 3O7QA 4GBZA 4IKVA 4JR9A 4QIQA 5D59A 4D2CA 4LEPA 4ZW9A 3O7PA 5D58A 4JA3A
chains in the Genus database with same CATH superfamily
4NKQC 5C4XD 3SE3B 3OG4A 1Y6NL 1J7VL 4A3JD 3WDOA 1BP3A 1HIJA 4GC0A 1PV6A 4O6KA 4MHLA 4GBYA 5A2NA 3UEZE 3O7QA 4JR9A 1M4CA 1BGDA 3HOXD 2O6IA 5D58A 4BXXD 2D48A 4IKWA 4NN6A 4A3BD 1Z7CA 4PYPA 2C35A 4YBQA 5C3ED 3PO3D 1RFBA 1A7MA 5D6KA 4JREA 5GXBA 1QVNA 4TPHA 1KF9A 3L5WI 2L3YA 5C44D 1INRA 1AXIA 3NPZA 1IRLA 4A3MD 3H0GD 4EXNA 1V7MV 5EQHA 3VA2A 4W6VA 4A3LD 1BCNA 3IRHA 4PS4A 5L6YC 3G6DA 1ITFA 3AYHA 3H3VE 4YUEC 4DKEA 1GNCA 1HWHA 4OAAA 4D2CA 4IKVA 3TGXB 5D70A 2LAGA 4IU9A 5EQGA 4NN5A 4DKDA 1EXZA 1AX8A 1HIKA 3HOVD 2KZ1A 1AU1A 1RW5A 3QB1A 3OQ3A 3LB6B 1CN4C 5C7XA 1WCMD 4LDSA 4NEJA 1CNT1 2GMFA 1V7NV 2D9QA 5A2OA 2B91A 4A3GD 1A22A 4ZYRA 4IKYA 3S9DA 1B5LA 1PGRA 4D2BA 5EQIA 3NCCA 2IL6A 3HMXB 4EXPA 1WU3I 4ZS7A 3DGCL 2HYMB 3BPNA 3NCEA 5D22A 4NEMA 1HZIA 4J05A 1P9MB 1JLIA 4J4LC 2XUTA 4DOHA 3G9VB 1EVSA 3QB7A 1FG9A 3WCYI 2R93D 1CD9A 2B63D 1IL6A 3O7PA 4CNIC 1Y1WD 2CFPA 1CSGA 2V8NA 5IYBD 2Q14A 3MZGA 4TPJA 1CYLA 4U4TA 2R92D 3PO2D 5IP9D 4DKFA 3BPOA 2ILKA 3UF5A 2B8XA 2B8ZA 3DUHC 1FYHA 4YQXA 5KNHI 2Q7NB 1GA3A 3HOZD 4IKZA 5FHXA 2Z3RA 4BY1D 3HHRA 4A3CD 2R7ZD 2B8YA 2LMSA 2O26A 2PSMA 3I4ND 1HGUA 1VLKA 3L5XA 1PW6A 5D28B 2XQBA 1EERA 3DI3A 2JA8D 4BY7D 1BGCA 4A3ID 3HOWD 1LQSL 1EMRA 4A3FD 1ITMA 1PV7A 1LK3A 3INKC 3PIVA 3BPLA 2JA7D 1HWGA 1PVHB 3EW3A 2B90A 1M4AA 4UVMA 5FUCA 1BUYA 4GBZA 4D2DA 2CFQA 4LRLA 3UX9A 1IARA 3EJJA 5E4EA 5LQBA 4XNIA 2ERJD 2Y5YA 4X51A 4DKCA 4IKXA 1M49A 1BBNA 4ZF7A 3D48P 4U4WA 4NI9A 1EKUA 4QIQA 4LEPA 4ZW9A 4JA3A 3HOYD 5IYCD 4Q65A 4A3KD 2B5IA 4OH3A 1M47A 2OQPA 1M4BA 4O9HA 1LKIA 4GRWA 2H24A 1HUWA 1Y1VD 1Z92A 4NI7A 1ITLA 4BBSD 3Q1SI 4WRLB 2VUMD 1ETEA 3I4MD 1ALUA 4APSA 3QAZA 4YDYI 1RCBA 1D9GA 3N0PA 5FLMD 4YPGC 3PIWA 5C65A 1ILKA 4RS1A 5TS9A 4TPGA 2Z3QA 1PW4A 2INTA 3D85C 5D59A 1ITIA 4GS7A 1Y6KL 1F45B 3QWRB 4BBRD 3DI2A 1BGEA 2JA6D 4U4VA 4NN7A 3HHCA 3OG6A 4Z5RD 4YB9D 3HOUD 3BESL 1IK0A 1M48A 4ZWBA 3B5KA 3DLQI 1M4RA 2B8UA 4A93D 3N06A 2JA5D 3LB6A 1I1RB 2CYKA 4A3ED 3D87A 2E9WC 4XNJA 1IJZA 3QT2C 3SE4B 3UF2A 3FKID 4ZWCA 1Y14A 1F6FA 1NBPA 1Y6ML 1N1FA 4I77Z 2O27A 1SCFA 2L3OA 1YKBA 5D71A 4IU8A 3NCFA 5IP7D 1PY2A 2Q98A 1HULA 1D9CA 3NCBA 4A3DD 5IYDD 1RHGA 5D72A 4FA8E
chains in the Genus database with same CATH topology
2CFQA 1PV7A 4IU9A 4IKWA 5EQGA 5A2OA 4APSA 4PYPA 5EQHA 4Q65A 4W6VA 2CFPA 4IU8A 4OH3A 4ZYRA 4U4VA 3WDOA 4XNIA 2V8NA 4J05A 4YBQA 5C65A 4IKYA 2Y5YA 4GC0A 4YB9D 4IKXA 1PV6A 4IKZA 5D6KA 2XUTA 4JREA 4TPJA 4XNJA 4TPGA 4D2BA 4GBYA 5EQIA 1PW4A 5GXBA 4D2DA 4LDSA 4U4WA 4U4TA 4ZWCA 5A2NA 4TPHA 4ZWBA 4OAAA 4UVMA 3O7QA 4GBZA 4IKVA 4JR9A 4QIQA 5D59A 4D2CA 4LEPA 4ZW9A 3O7PA 5D58A 4JA3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CFQ A;  1PV7 A;  4IU9 A;  4IKW A;  5EQG A;  5A2O A;  4APS A;  4PYP A;  5EQH A;  4Q65 A;  4W6V A;  2CFP A;  4IU8 A;  4OH3 A;  4ZYR A;  4U4V A;  3WDO A;  4XNI A;  2V8N A;  4J05 A;  4YBQ A;  5C65 A;  4IKY A;  2Y5Y A;  4GC0 A;  4YB9 D;  4IKX A;  1PV6 A;  4IKZ A;  5D6K A;  2XUT A;  4JRE A;  4TPJ A;  4XNJ A;  4TPG A;  4D2B A;  4GBY A;  5EQI A;  1PW4 A;  5GXB A;  4D2D A;  4LDS A;  4U4W A;  4U4T A;  4ZWC A;  5A2N A;  4TPH A;  4ZWB A;  4OAA A;  4UVM A;  3O7Q A;  4GBZ A;  4IKV A;  4JR9 A;  4QIQ A;  5D59 A;  4D2C A;  4LEP A;  4ZW9 A;  3O7P A;  5D58 A;  4JA3 A; 
#chains in the Genus database with same CATH topology
 4NKQ C;  5C4X D;  3SE3 B;  3OG4 A;  1Y6N L;  1J7V L;  4A3J D;  3WDO A;  1BP3 A;  1HIJ A;  4GC0 A;  1PV6 A;  4O6K A;  4MHL A;  4GBY A;  5A2N A;  3UEZ E;  3O7Q A;  4JR9 A;  1M4C A;  1BGD A;  3HOX D;  2O6I A;  5D58 A;  4BXX D;  2D48 A;  4IKW A;  4NN6 A;  4A3B D;  1Z7C A;  4PYP A;  2C35 A;  4YBQ A;  5C3E D;  3PO3 D;  1RFB A;  1A7M A;  5D6K A;  4JRE A;  5GXB A;  1QVN A;  4TPH A;  1KF9 A;  3L5W I;  2L3Y A;  5C44 D;  1INR A;  1AXI A;  3NPZ A;  1IRL A;  4A3M D;  3H0G D;  4EXN A;  1V7M V;  5EQH A;  3VA2 A;  4W6V A;  4A3L D;  1BCN A;  3IRH A;  4PS4 A;  5L6Y C;  3G6D A;  1ITF A;  3AYH A;  3H3V E;  4YUE C;  4DKE A;  1GNC A;  1HWH A;  4OAA A;  4D2C A;  4IKV A;  3TGX B;  5D70 A;  2LAG A;  4IU9 A;  5EQG A;  4NN5 A;  4DKD A;  1EXZ A;  1AX8 A;  1HIK A;  3HOV D;  2KZ1 A;  1AU1 A;  1RW5 A;  3QB1 A;  3OQ3 A;  3LB6 B;  1CN4 C;  5C7X A;  1WCM D;  4LDS A;  4NEJ A;  1CNT 1;  2GMF A;  1V7N V;  2D9Q A;  5A2O A;  2B91 A;  4A3G D;  1A22 A;  4ZYR A;  4IKY A;  3S9D A;  1B5L A;  1PGR A;  4D2B A;  5EQI A;  3NCC A;  2IL6 A;  3HMX B;  4EXP A;  1WU3 I;  4ZS7 A;  3DGC L;  2HYM B;  3BPN A;  3NCE A;  5D22 A;  4NEM A;  1HZI A;  4J05 A;  1P9M B;  1JLI A;  4J4L C;  2XUT A;  4DOH A;  3G9V B;  1EVS A;  3QB7 A;  1FG9 A;  3WCY I;  2R93 D;  1CD9 A;  2B63 D;  1IL6 A;  3O7P A;  4CNI C;  1Y1W D;  2CFP A;  1CSG A;  2V8N A;  5IYB D;  2Q14 A;  3MZG A;  4TPJ A;  1CYL A;  4U4T A;  2R92 D;  3PO2 D;  5IP9 D;  4DKF A;  3BPO A;  2ILK A;  3UF5 A;  2B8X A;  2B8Z A;  3DUH C;  1FYH A;  4YQX A;  5KNH I;  2Q7N B;  1GA3 A;  3HOZ D;  4IKZ A;  5FHX A;  2Z3R A;  4BY1 D;  3HHR A;  4A3C D;  2R7Z D;  2B8Y A;  2LMS A;  2O26 A;  2PSM A;  3I4N D;  1HGU A;  1VLK A;  3L5X A;  1PW6 A;  5D28 B;  2XQB A;  1EER A;  3DI3 A;  2JA8 D;  4BY7 D;  1BGC A;  4A3I D;  3HOW D;  1LQS L;  1EMR A;  4A3F D;  1ITM A;  1PV7 A;  1LK3 A;  3INK C;  3PIV A;  3BPL A;  2JA7 D;  1HWG A;  1PVH B;  3EW3 A;  2B90 A;  1M4A A;  4UVM A;  5FUC A;  1BUY A;  4GBZ A;  4D2D A;  2CFQ A;  4LRL A;  3UX9 A;  1IAR A;  3EJJ A;  5E4E A;  5LQB A;  4XNI A;  2ERJ D;  2Y5Y A;  4X51 A;  4DKC A;  4IKX A;  1M49 A;  1BBN A;  4ZF7 A;  3D48 P;  4U4W A;  4NI9 A;  1EKU A;  4QIQ A;  4LEP A;  4ZW9 A;  4JA3 A;  3HOY D;  5IYC D;  4Q65 A;  4A3K D;  2B5I A;  4OH3 A;  1M47 A;  2OQP A;  1M4B A;  4O9H A;  1LKI A;  4GRW A;  2H24 A;  1HUW A;  1Y1V D;  1Z92 A;  4NI7 A;  1ITL A;  4BBS D;  3Q1S I;  4WRL B;  2VUM D;  1ETE A;  3I4M D;  1ALU A;  4APS A;  3QAZ A;  4YDY I;  1RCB A;  1D9G A;  3N0P A;  5FLM D;  4YPG C;  3PIW A;  5C65 A;  1ILK A;  4RS1 A;  5TS9 A;  4TPG A;  2Z3Q A;  1PW4 A;  2INT A;  3D85 C;  5D59 A;  1ITI A;  4GS7 A;  1Y6K L;  1F45 B;  3QWR B;  4BBR D;  3DI2 A;  1BGE A;  2JA6 D;  4U4V A;  4NN7 A;  3HHC A;  3OG6 A;  4Z5R D;  4YB9 D;  3HOU D;  3BES L;  1IK0 A;  1M48 A;  4ZWB A;  3B5K A;  3DLQ I;  1M4R A;  2B8U A;  4A93 D;  3N06 A;  2JA5 D;  3LB6 A;  1I1R B;  2CYK A;  4A3E D;  3D87 A;  2E9W C;  4XNJ A;  1IJZ A;  3QT2 C;  3SE4 B;  3UF2 A;  3FKI D;  4ZWC A;  1Y14 A;  1F6F A;  1NBP A;  1Y6M L;  1N1F A;  4I77 Z;  2O27 A;  1SCF A;  2L3O A;  1YKB A;  5D71 A;  4IU8 A;  3NCF A;  5IP7 D;  1PY2 A;  2Q98 A;  1HUL A;  1D9C A;  3NCB A;  4A3D D;  5IYD D;  1RHG A;  5D72 A;  4FA8 E; 
#chains in the Genus database with same CATH homology
 2CFQ A;  1PV7 A;  4IU9 A;  4IKW A;  5EQG A;  5A2O A;  4APS A;  4PYP A;  5EQH A;  4Q65 A;  4W6V A;  2CFP A;  4IU8 A;  4OH3 A;  4ZYR A;  4U4V A;  3WDO A;  4XNI A;  2V8N A;  4J05 A;  4YBQ A;  5C65 A;  4IKY A;  2Y5Y A;  4GC0 A;  4YB9 D;  4IKX A;  1PV6 A;  4IKZ A;  5D6K A;  2XUT A;  4JRE A;  4TPJ A;  4XNJ A;  4TPG A;  4D2B A;  4GBY A;  5EQI A;  1PW4 A;  5GXB A;  4D2D A;  4LDS A;  4U4W A;  4U4T A;  4ZWC A;  5A2N A;  4TPH A;  4ZWB A;  4OAA A;  4UVM A;  3O7Q A;  4GBZ A;  4IKV A;  4JR9 A;  4QIQ A;  5D59 A;  4D2C A;  4LEP A;  4ZW9 A;  3O7P A;  5D58 A;  4JA3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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