4ZWC | Genus

Total Genus 197

Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	197
sequence length	468
structure length	468
Chain Sequence	TQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFITKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAH

Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__64145835010765__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__64145835010765__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/4ZWC/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__64145835010765__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"64145835010765","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/4ZWC/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__64145835010765__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transport protein
source organism	Homo sapiens
publication title	Molecular basis of ligand recognition and transport by glucose transporters pubmed doi rcsb
molecule keywords	Solute carrier family 2, facilitated glucose transporter mem
total genus	197
structure length	468
sequence length	468
chains with identical sequence	B
ec nomenclature
pdb deposition date	2015-05-19

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00083	Sugar_tr	Sugar (and other) transporter

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.1250.20	Mainly Alpha	Up-down Bundle	Growth Hormone; Chain: A;	MFS general substrate transporter like domains	4zwcA00

4ZWBA 2CFPA 4TPGA 4TPJA 5A2OA 4YBQA 4J05A 4IU9A 4ZWCA 4GC0A 4IKZA 4XNJA 4ZYRA 5EQGA 4IKWA 1PV6A 5D58A 4ZW9A 4D2CA 4APSA 4JREA 1PV7A 2Y5YA 4IU8A 4LEPA 4Q65A 1PW4A 3O7QA 4OH3A 5GXBA 4YB9D 4IKVA 4D2DA 4GBZA 5D6KA 4TPHA 5C65A 4IKXA 4QIQA 4GBYA 3WDOA 2CFQA 4U4TA 2XUTA 4U4VA 4UVMA 4JA3A 5D59A 5EQIA 4U4WA 4IKYA 4PYPA 4LDSA 4JR9A 4OAAA 4W6VA 4D2BA 2V8NA 3O7PA 4XNIA 5EQHA 5A2NA
chains in the Genus database with same CATH superfamily

1HWGA 1BGCA 1EXZA 5A2OA 4GS7A 1EKUA 3EW3A 4ZW9A 4BY1D 1LK3A 4EXPA 3D87A 4Z5RD 4A3GD 3HMXB 4IKYA 2GMFA 3PO3D 3D48P 4XNIA 1ITIA 1ILKA 3HOUD 2B8XA 3H0GD 1PY2A 1PVHB 2INTA 5D28B 3HOXD 4NEJA 2D9QA 1HUWA 2O6IA 3BPLA 4W6VA 4WRLB 2B8ZA 1PGRA 2Q14A 1CN4C 5FHXA 5GXBA 1Y6KL 1ETEA 2VUMD 4QIQA 3G9VB 3DUHC 2O26A 3NCFA 2Q7NB 2R93D 2R7ZD 2B90A 5C4XD 4NN7A 5D70A 4A3DD 4YBQA 4D2CA 1PV7A 1PW4A 1JLIA 1KF9A 1CSGA 3LB6A 4BY7D 2CYKA 2IL6A 2E9WC 4TPGA 4J05A 4ZWCA 4XNJA 4IKZA 1FYHA 1N1FA 1CD9A 4YPGC 3PIVA 4IKXA 1D9GA 1YKBA 2CFQA 4U4TA 4A3MD 1RFBA 1V7MV 3NCEA 4A3CD 2V8NA 4BBRD 2R92D 4DOHA 1IRLA 1ITLA 1RW5A 2D48A 3NCBA 1GNCA 2B5IA 1Y6ML 2L3OA 3O7QA 1M4BA 4OH3A 1AX8A 5IYDD 1VLKA 4EXNA 1BGDA 3QT2C 5IYBD 4I77Z 2B8UA 1AU1A 3INKC 4PYPA 1LKIA 4A3KD 3N06A 3PO2D 3B5KA 3EJJA 4NI9A 4APSA 4LEPA 4YB9D 4D2DA 4GBZA 2B63D 4U4VA 3OG6A 3LB6B 1IJZA 1SCFA 1J7VL 1CYLA 3TGXB 2Z3RA 1WCMD 1A7MA 2ERJD 3UF5A 2Y5YA 4IU8A 1RHGA 4A3JD 2Q98A 4IKVA 3DLQI 5D6KA 2JA6D 4GBYA 3L5WI 4CNIC 2XUTA 4X51A 5LQBA 4JR9A 5C7XA 5A2NA 1IK0A 4TPJA 4NI7A 1M4RA 3VA2A 5D71A 1Z92A 1V7NV 1HIJA 2OQPA 1F6FA 2JA5D 3QAZA 1QVNA 4BXXD 4NEMA 3I4MD 3H3VE 1LQSL 1I1RB 3IRHA 5EQGA 3S9DA 5D58A 1HZIA 4A93D 3QB1A 4JREA 2H24A 1CNT1 2B91A 1ITMA 4FA8E 3NPZA 3BPNA 4UVMA 4A3BD 1D9CA 1Y1WD 5IP7D 2CFPA 4O6KA 4IU9A 4ZYRA 1PV6A 1INRA 1ALUA 4DKEA 1EVSA 3HOVD 4DKFA 3HOYD 2LMSA 1F45B 1HULA 3N0PA 4NKQC 5IP9D 3SE4B 4A3LD 3Q1SI 4A3ID 1M49A 3NCCA 4ZWBA 5KNHI 4ZS7A 1BP3A 3UF2A 3OG4A 3I4ND 3AYHA 5C3ED 5E4EA 3DI2A 2L3YA 3WDOA 1PW6A 1NBPA 1BGEA 4JA3A 3OQ3A 4U4WA 3UEZE 4D2BA 2Z3QA 3BPOA 2O27A 3HHRA 2PSMA 1IARA 1Z7CA 1EERA 3DGCL 4YDYI 5D22A 4LRLA 4YUEC 5C65A 3QWRB 2LAGA 1ITFA 1GA3A 4GRWA 3G6DA 5EQHA 3PIWA 4DKDA 1BUYA 4NN5A 1P9MB 4IKWA 5FUCA 2ILKA 1RCBA 4DKCA 2JA8D 5L6YC 4TPHA 3HOWD 1BBNA 1HIKA 1HWHA 5FLMD 1IL6A 2JA7D 4LDSA 1Y6NL 4RS1A 5C44D 3BESL 3MZGA 4NN6A 4A3ED 3HHCA 3SE3B 1Y1VD 1BCNA 1WU3I 2XQBA 3QB7A 4Q65A 2B8YA 4J4LC 4O9HA 5D72A 2HYMB 3D85C 1M48A 1FG9A 2C35A 5EQIA 1M4CA 4A3FD 3O7PA 4MHLA 4PS4A 1B5LA 3HOZD 3L5XA 1A22A 4GC0A 3WCYI 4ZF7A 1AXIA 1Y14A 5IYCD 3FKID 2KZ1A 1HGUA 1M47A 5TS9A 3DI3A 1M4AA 5D59A 4BBSD 4YQXA 1EMRA 4OAAA 3UX9A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4ZWB A;  2CFP A;  4TPG A;  4TPJ A;  5A2O A;  4YBQ A;  4J05 A;  4IU9 A;  4ZWC A;  4GC0 A;  4IKZ A;  4XNJ A;  4ZYR A;  5EQG A;  4IKW A;  1PV6 A;  5D58 A;  4ZW9 A;  4D2C A;  4APS A;  4JRE A;  1PV7 A;  2Y5Y A;  4IU8 A;  4LEP A;  4Q65 A;  1PW4 A;  3O7Q A;  4OH3 A;  5GXB A;  4YB9 D;  4IKV A;  4D2D A;  4GBZ A;  5D6K A;  4TPH A;  5C65 A;  4IKX A;  4QIQ A;  4GBY A;  3WDO A;  2CFQ A;  4U4T A;  2XUT A;  4U4V A;  4UVM A;  4JA3 A;  5D59 A;  5EQI A;  4U4W A;  4IKY A;  4PYP A;  4LDS A;  4JR9 A;  4OAA A;  4W6V A;  4D2B A;  2V8N A;  3O7P A;  4XNI A;  5EQH A;  5A2N A; 
#chains in the Genus database with same CATH topology
 1HWG A;  1BGC A;  1EXZ A;  5A2O A;  4GS7 A;  1EKU A;  3EW3 A;  4ZW9 A;  4BY1 D;  1LK3 A;  4EXP A;  3D87 A;  4Z5R D;  4A3G D;  3HMX B;  4IKY A;  2GMF A;  3PO3 D;  3D48 P;  4XNI A;  1ITI A;  1ILK A;  3HOU D;  2B8X A;  3H0G D;  1PY2 A;  1PVH B;  2INT A;  5D28 B;  3HOX D;  4NEJ A;  2D9Q A;  1HUW A;  2O6I A;  3BPL A;  4W6V A;  4WRL B;  2B8Z A;  1PGR A;  2Q14 A;  1CN4 C;  5FHX A;  5GXB A;  1Y6K L;  1ETE A;  2VUM D;  4QIQ A;  3G9V B;  3DUH C;  2O26 A;  3NCF A;  2Q7N B;  2R93 D;  2R7Z D;  2B90 A;  5C4X D;  4NN7 A;  5D70 A;  4A3D D;  4YBQ A;  4D2C A;  1PV7 A;  1PW4 A;  1JLI A;  1KF9 A;  1CSG A;  3LB6 A;  4BY7 D;  2CYK A;  2IL6 A;  2E9W C;  4TPG A;  4J05 A;  4ZWC A;  4XNJ A;  4IKZ A;  1FYH A;  1N1F A;  1CD9 A;  4YPG C;  3PIV A;  4IKX A;  1D9G A;  1YKB A;  2CFQ A;  4U4T A;  4A3M D;  1RFB A;  1V7M V;  3NCE A;  4A3C D;  2V8N A;  4BBR D;  2R92 D;  4DOH A;  1IRL A;  1ITL A;  1RW5 A;  2D48 A;  3NCB A;  1GNC A;  2B5I A;  1Y6M L;  2L3O A;  3O7Q A;  1M4B A;  4OH3 A;  1AX8 A;  5IYD D;  1VLK A;  4EXN A;  1BGD A;  3QT2 C;  5IYB D;  4I77 Z;  2B8U A;  1AU1 A;  3INK C;  4PYP A;  1LKI A;  4A3K D;  3N06 A;  3PO2 D;  3B5K A;  3EJJ A;  4NI9 A;  4APS A;  4LEP A;  4YB9 D;  4D2D A;  4GBZ A;  2B63 D;  4U4V A;  3OG6 A;  3LB6 B;  1IJZ A;  1SCF A;  1J7V L;  1CYL A;  3TGX B;  2Z3R A;  1WCM D;  1A7M A;  2ERJ D;  3UF5 A;  2Y5Y A;  4IU8 A;  1RHG A;  4A3J D;  2Q98 A;  4IKV A;  3DLQ I;  5D6K A;  2JA6 D;  4GBY A;  3L5W I;  4CNI C;  2XUT A;  4X51 A;  5LQB A;  4JR9 A;  5C7X A;  5A2N A;  1IK0 A;  4TPJ A;  4NI7 A;  1M4R A;  3VA2 A;  5D71 A;  1Z92 A;  1V7N V;  1HIJ A;  2OQP A;  1F6F A;  2JA5 D;  3QAZ A;  1QVN A;  4BXX D;  4NEM A;  3I4M D;  3H3V E;  1LQS L;  1I1R B;  3IRH A;  5EQG A;  3S9D A;  5D58 A;  1HZI A;  4A93 D;  3QB1 A;  4JRE A;  2H24 A;  1CNT 1;  2B91 A;  1ITM A;  4FA8 E;  3NPZ A;  3BPN A;  4UVM A;  4A3B D;  1D9C A;  1Y1W D;  5IP7 D;  2CFP A;  4O6K A;  4IU9 A;  4ZYR A;  1PV6 A;  1INR A;  1ALU A;  4DKE A;  1EVS A;  3HOV D;  4DKF A;  3HOY D;  2LMS A;  1F45 B;  1HUL A;  3N0P A;  4NKQ C;  5IP9 D;  3SE4 B;  4A3L D;  3Q1S I;  4A3I D;  1M49 A;  3NCC A;  4ZWB A;  5KNH I;  4ZS7 A;  1BP3 A;  3UF2 A;  3OG4 A;  3I4N D;  3AYH A;  5C3E D;  5E4E A;  3DI2 A;  2L3Y A;  3WDO A;  1PW6 A;  1NBP A;  1BGE A;  4JA3 A;  3OQ3 A;  4U4W A;  3UEZ E;  4D2B A;  2Z3Q A;  3BPO A;  2O27 A;  3HHR A;  2PSM A;  1IAR A;  1Z7C A;  1EER A;  3DGC L;  4YDY I;  5D22 A;  4LRL A;  4YUE C;  5C65 A;  3QWR B;  2LAG A;  1ITF A;  1GA3 A;  4GRW A;  3G6D A;  5EQH A;  3PIW A;  4DKD A;  1BUY A;  4NN5 A;  1P9M B;  4IKW A;  5FUC A;  2ILK A;  1RCB A;  4DKC A;  2JA8 D;  5L6Y C;  4TPH A;  3HOW D;  1BBN A;  1HIK A;  1HWH A;  5FLM D;  1IL6 A;  2JA7 D;  4LDS A;  1Y6N L;  4RS1 A;  5C44 D;  3BES L;  3MZG A;  4NN6 A;  4A3E D;  3HHC A;  3SE3 B;  1Y1V D;  1BCN A;  1WU3 I;  2XQB A;  3QB7 A;  4Q65 A;  2B8Y A;  4J4L C;  4O9H A;  5D72 A;  2HYM B;  3D85 C;  1M48 A;  1FG9 A;  2C35 A;  5EQI A;  1M4C A;  4A3F D;  3O7P A;  4MHL A;  4PS4 A;  1B5L A;  3HOZ D;  3L5X A;  1A22 A;  4GC0 A;  3WCY I;  4ZF7 A;  1AXI A;  1Y14 A;  5IYC D;  3FKI D;  2KZ1 A;  1HGU A;  1M47 A;  5TS9 A;  3DI3 A;  1M4A A;  5D59 A;  4BBS D;  4YQX A;  1EMR A;  4OAA A;  3UX9 A; 
#chains in the Genus database with same CATH homology
 4ZWB A;  2CFP A;  4TPG A;  4TPJ A;  5A2O A;  4YBQ A;  4J05 A;  4IU9 A;  4ZWC A;  4GC0 A;  4IKZ A;  4XNJ A;  4ZYR A;  5EQG A;  4IKW A;  1PV6 A;  5D58 A;  4ZW9 A;  4D2C A;  4APS A;  4JRE A;  1PV7 A;  2Y5Y A;  4IU8 A;  4LEP A;  4Q65 A;  1PW4 A;  3O7Q A;  4OH3 A;  5GXB A;  4YB9 D;  4IKV A;  4D2D A;  4GBZ A;  5D6K A;  4TPH A;  5C65 A;  4IKX A;  4QIQ A;  4GBY A;  3WDO A;  2CFQ A;  4U4T A;  2XUT A;  4U4V A;  4UVM A;  4JA3 A;  5D59 A;  5EQI A;  4U4W A;  4IKY A;  4PYP A;  4LDS A;  4JR9 A;  4OAA A;  4W6V A;  4D2B A;  2V8N A;  3O7P A;  4XNI A;  5EQH A;  5A2N A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

4ZWCA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations