4ZWCA

Crystal structure of maltose-bound human glut3 in the outward-open conformation at 2.6 angstrom
Total Genus 197
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
197
sequence length
468
structure length
468
Chain Sequence
TQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFITKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of ligand recognition and transport by glucose transporters
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Solute carrier family 2, facilitated glucose transporter mem
total genus 197
structure length 468
sequence length 468
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4zwcA00
4OH3A 4IKVA 5C65A 4IKXA 4D2CA 3O7QA 2V8NA 4ZW9A 5D58A 4LEPA 5GXBA 4JREA 4QIQA 2CFPA 1PV7A 5EQGA 4JA3A 5D6KA 1PV6A 4ZWCA 4GC0A 4ZWBA 2Y5YA 4IKYA 4GBYA 5D59A 1PW4A 4IU8A 4YB9D 4TPGA 4U4WA 4UVMA 3WDOA 3O7PA 4U4VA 4JR9A 4D2DA 2CFQA 4XNJA 4IKZA 5A2NA 4IU9A 5EQIA 4XNIA 4D2BA 4TPHA 4YBQA 4ZYRA 4J05A 4APSA 4W6VA 4PYPA 4Q65A 5EQHA 4U4TA 2XUTA 4IKWA 4LDSA 5A2OA 4OAAA 4GBZA 4TPJA
chains in the Genus database with same CATH superfamily
1M4BA 4QIQA 1V7MV 3OG4A 3NCEA 1CNT1 1P9MB 4IKZA 1A22A 4A3KD 2R93D 3IRHA 2KZ1A 2H24A 1BUYA 3DI2A 4IKVA 4ZW9A 1EKUA 2VUMD 2JA6D 2B91A 4ZWBA 1AX8A 3G9VB 1FYHA 3S9DA 1LQSL 1VLKA 5A2NA 4XNIA 1F45B 1ETEA 1HIKA 5E4EA 2E9WC 4IKWA 2JA5D 1Y1VD 2Y5YA 1CYLA 5C7XA 3WDOA 3HMXB 4YQXA 3DLQI 1HZIA 5C44D 2Q14A 4APSA 2B63D 3NCFA 4A3JD 3AYHA 4YPGC 4X51A 4GS7A 4TPJA 3B5KA 2OQPA 1F6FA 4LEPA 1PY2A 3PO3D 2CFPA 2L3YA 2B8XA 2PSMA 1Y14A 2B8YA 2Z3QA 2XQBA 1PW4A 4U4WA 3DI3A 1Z92A 1PGRA 5EQIA 4A3DD 4EXNA 4PYPA 1BCNA 1LKIA 1V7NV 4NN6A 4IKXA 5D22A 5IP7D 4DKCA 1A7MA 4LRLA 1INRA 1M4RA 2R7ZD 4WRLB 3EW3A 3LB6B 5TS9A 2CFQA 4XNJA 4NKQC 1Y1WD 4CNIC 3BPNA 1AU1A 1PW6A 3HHRA 4NEJA 1YKBA 3UX9A 3QWRB 4OAAA 1HWGA 2B8ZA 2L3OA 2JA7D 4JA3A 3VA2A 4A3MD 3O7PA 4PS4A 1GA3A 3NCBA 1BBNA 3G6DA 1ITMA 3HOWD 1IJZA 4DOHA 1IRLA 3BESL 1D9GA 4U4TA 3L5XA 1CSGA 1Y6ML 3NPZA 5C65A 4I77Z 1EMRA 4JREA 3TGXB 1M4CA 1Y6KL 2INTA 2D48A 4U4VA 4YUEC 4JR9A 1ILKA 3HOVD 4NN5A 5L6YC 1KF9A 3L5WI 4LDSA 3QB7A 4NI9A 1IL6A 1HGUA 3QB1A 4ZF7A 5FLMD 1B5LA 3DUHC 4EXPA 4GC0A 5D70A 3QAZA 2B5IA 4IU9A 5IYDD 4TPHA 4ZYRA 2R92D 4BY7D 1HWHA 1RCBA 4OH3A 4BY1D 1IK0A 2HYMB 1FG9A 3N0PA 4A3FD 4A3ID 1WCMD 4O9HA 5IYCD 3Q1SI 2LMSA 2GMFA 1M47A 3I4MD 4RS1A 3HOYD 4O6KA 4J05A 2O27A 1J7VL 4A93D 1Y6NL 4ZWCA 4BBRD 4DKFA 5KNHI 4YB9D 2O26A 3PIVA 2D9QA 1N1FA 4YBQA 3D48P 1NBPA 1CD9A 1RHGA 1EXZA 1SCFA 5FUCA 3N06A 2Z3RA 2C35A 2V8NA 5D58A 1PV7A 1ITLA 1HULA 3D87A 3SE4B 2ERJD 1ITFA 3D85C 5IYBD 2O6IA 2IL6A 3OQ3A 1BGEA 1IARA 1WU3I 4A3CD 3BPLA 5EQGA 3LB6A 1CN4C 5D6KA 1PV6A 3EJJA 4YDYI 3QT2C 4TPGA 5C4XD 1I1RB 5LQBA 4GRWA 4A3ED 2B8UA 4MHLA 3FKID 5D71A 5D28B 4BBSD 3OG6A 3UEZE 4D2CA 5GXBA 2JA8D 1M4AA 1M49A 1JLIA 4GBYA 5D59A 1GNCA 4D2DA 1EVSA 4NEMA 4D2BA 1HIJA 2CYKA 1BGDA 4BXXD 3UF2A 3INKC 5FHXA 5A2OA 3PO2D 4DKDA 3PIWA 3O7QA 1M48A 3H3VE 3UF5A 5D72A 2Q7NB 4W6VA 1BGCA 1D9CA 5IP9D 2XUTA 4GBZA 4NN7A 1RFBA 1LK3A 3NCCA 3I4ND 2B90A 3DGCL 2LAGA 1PVHB 4FA8E 3HOUD 4IU8A 3SE3B 1AXIA 4NI7A 5C3ED 1ITIA 4Z5RD 2ILKA 2Q98A 1RW5A 4A3LD 4Q65A 3BPOA 1EERA 4J4LC 3MZGA 1QVNA 1Z7CA 3WCYI 3HOXD 3HOZD 4A3GD 4IKYA 4UVMA 1HUWA 3H0GD 1BP3A 1ALUA 4A3BD 5EQHA 3HHCA 4ZS7A 4DKEA
chains in the Genus database with same CATH topology
4OH3A 4IKVA 5C65A 4IKXA 4D2CA 3O7QA 2V8NA 4ZW9A 5D58A 4LEPA 5GXBA 4JREA 4QIQA 2CFPA 1PV7A 5EQGA 4JA3A 5D6KA 1PV6A 4ZWCA 4GC0A 4ZWBA 2Y5YA 4IKYA 4GBYA 5D59A 1PW4A 4IU8A 4YB9D 4TPGA 4U4WA 4UVMA 3WDOA 3O7PA 4U4VA 4JR9A 4D2DA 2CFQA 4XNJA 4IKZA 5A2NA 4IU9A 5EQIA 4XNIA 4D2BA 4TPHA 4YBQA 4ZYRA 4J05A 4APSA 4W6VA 4PYPA 4Q65A 5EQHA 4U4TA 2XUTA 4IKWA 4LDSA 5A2OA 4OAAA 4GBZA 4TPJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OH3 A;  4IKV A;  5C65 A;  4IKX A;  4D2C A;  3O7Q A;  2V8N A;  4ZW9 A;  5D58 A;  4LEP A;  5GXB A;  4JRE A;  4QIQ A;  2CFP A;  1PV7 A;  5EQG A;  4JA3 A;  5D6K A;  1PV6 A;  4ZWC A;  4GC0 A;  4ZWB A;  2Y5Y A;  4IKY A;  4GBY A;  5D59 A;  1PW4 A;  4IU8 A;  4YB9 D;  4TPG A;  4U4W A;  4UVM A;  3WDO A;  3O7P A;  4U4V A;  4JR9 A;  4D2D A;  2CFQ A;  4XNJ A;  4IKZ A;  5A2N A;  4IU9 A;  5EQI A;  4XNI A;  4D2B A;  4TPH A;  4YBQ A;  4ZYR A;  4J05 A;  4APS A;  4W6V A;  4PYP A;  4Q65 A;  5EQH A;  4U4T A;  2XUT A;  4IKW A;  4LDS A;  5A2O A;  4OAA A;  4GBZ A;  4TPJ A; 
#chains in the Genus database with same CATH topology
 1M4B A;  4QIQ A;  1V7M V;  3OG4 A;  3NCE A;  1CNT 1;  1P9M B;  4IKZ A;  1A22 A;  4A3K D;  2R93 D;  3IRH A;  2KZ1 A;  2H24 A;  1BUY A;  3DI2 A;  4IKV A;  4ZW9 A;  1EKU A;  2VUM D;  2JA6 D;  2B91 A;  4ZWB A;  1AX8 A;  3G9V B;  1FYH A;  3S9D A;  1LQS L;  1VLK A;  5A2N A;  4XNI A;  1F45 B;  1ETE A;  1HIK A;  5E4E A;  2E9W C;  4IKW A;  2JA5 D;  1Y1V D;  2Y5Y A;  1CYL A;  5C7X A;  3WDO A;  3HMX B;  4YQX A;  3DLQ I;  1HZI A;  5C44 D;  2Q14 A;  4APS A;  2B63 D;  3NCF A;  4A3J D;  3AYH A;  4YPG C;  4X51 A;  4GS7 A;  4TPJ A;  3B5K A;  2OQP A;  1F6F A;  4LEP A;  1PY2 A;  3PO3 D;  2CFP A;  2L3Y A;  2B8X A;  2PSM A;  1Y14 A;  2B8Y A;  2Z3Q A;  2XQB A;  1PW4 A;  4U4W A;  3DI3 A;  1Z92 A;  1PGR A;  5EQI A;  4A3D D;  4EXN A;  4PYP A;  1BCN A;  1LKI A;  1V7N V;  4NN6 A;  4IKX A;  5D22 A;  5IP7 D;  4DKC A;  1A7M A;  4LRL A;  1INR A;  1M4R A;  2R7Z D;  4WRL B;  3EW3 A;  3LB6 B;  5TS9 A;  2CFQ A;  4XNJ A;  4NKQ C;  1Y1W D;  4CNI C;  3BPN A;  1AU1 A;  1PW6 A;  3HHR A;  4NEJ A;  1YKB A;  3UX9 A;  3QWR B;  4OAA A;  1HWG A;  2B8Z A;  2L3O A;  2JA7 D;  4JA3 A;  3VA2 A;  4A3M D;  3O7P A;  4PS4 A;  1GA3 A;  3NCB A;  1BBN A;  3G6D A;  1ITM A;  3HOW D;  1IJZ A;  4DOH A;  1IRL A;  3BES L;  1D9G A;  4U4T A;  3L5X A;  1CSG A;  1Y6M L;  3NPZ A;  5C65 A;  4I77 Z;  1EMR A;  4JRE A;  3TGX B;  1M4C A;  1Y6K L;  2INT A;  2D48 A;  4U4V A;  4YUE C;  4JR9 A;  1ILK A;  3HOV D;  4NN5 A;  5L6Y C;  1KF9 A;  3L5W I;  4LDS A;  3QB7 A;  4NI9 A;  1IL6 A;  1HGU A;  3QB1 A;  4ZF7 A;  5FLM D;  1B5L A;  3DUH C;  4EXP A;  4GC0 A;  5D70 A;  3QAZ A;  2B5I A;  4IU9 A;  5IYD D;  4TPH A;  4ZYR A;  2R92 D;  4BY7 D;  1HWH A;  1RCB A;  4OH3 A;  4BY1 D;  1IK0 A;  2HYM B;  1FG9 A;  3N0P A;  4A3F D;  4A3I D;  1WCM D;  4O9H A;  5IYC D;  3Q1S I;  2LMS A;  2GMF A;  1M47 A;  3I4M D;  4RS1 A;  3HOY D;  4O6K A;  4J05 A;  2O27 A;  1J7V L;  4A93 D;  1Y6N L;  4ZWC A;  4BBR D;  4DKF A;  5KNH I;  4YB9 D;  2O26 A;  3PIV A;  2D9Q A;  1N1F A;  4YBQ A;  3D48 P;  1NBP A;  1CD9 A;  1RHG A;  1EXZ A;  1SCF A;  5FUC A;  3N06 A;  2Z3R A;  2C35 A;  2V8N A;  5D58 A;  1PV7 A;  1ITL A;  1HUL A;  3D87 A;  3SE4 B;  2ERJ D;  1ITF A;  3D85 C;  5IYB D;  2O6I A;  2IL6 A;  3OQ3 A;  1BGE A;  1IAR A;  1WU3 I;  4A3C D;  3BPL A;  5EQG A;  3LB6 A;  1CN4 C;  5D6K A;  1PV6 A;  3EJJ A;  4YDY I;  3QT2 C;  4TPG A;  5C4X D;  1I1R B;  5LQB A;  4GRW A;  4A3E D;  2B8U A;  4MHL A;  3FKI D;  5D71 A;  5D28 B;  4BBS D;  3OG6 A;  3UEZ E;  4D2C A;  5GXB A;  2JA8 D;  1M4A A;  1M49 A;  1JLI A;  4GBY A;  5D59 A;  1GNC A;  4D2D A;  1EVS A;  4NEM A;  4D2B A;  1HIJ A;  2CYK A;  1BGD A;  4BXX D;  3UF2 A;  3INK C;  5FHX A;  5A2O A;  3PO2 D;  4DKD A;  3PIW A;  3O7Q A;  1M48 A;  3H3V E;  3UF5 A;  5D72 A;  2Q7N B;  4W6V A;  1BGC A;  1D9C A;  5IP9 D;  2XUT A;  4GBZ A;  4NN7 A;  1RFB A;  1LK3 A;  3NCC A;  3I4N D;  2B90 A;  3DGC L;  2LAG A;  1PVH B;  4FA8 E;  3HOU D;  4IU8 A;  3SE3 B;  1AXI A;  4NI7 A;  5C3E D;  1ITI A;  4Z5R D;  2ILK A;  2Q98 A;  1RW5 A;  4A3L D;  4Q65 A;  3BPO A;  1EER A;  4J4L C;  3MZG A;  1QVN A;  1Z7C A;  3WCY I;  3HOX D;  3HOZ D;  4A3G D;  4IKY A;  4UVM A;  1HUW A;  3H0G D;  1BP3 A;  1ALU A;  4A3B D;  5EQH A;  3HHC A;  4ZS7 A;  4DKE A; 
#chains in the Genus database with same CATH homology
 4OH3 A;  4IKV A;  5C65 A;  4IKX A;  4D2C A;  3O7Q A;  2V8N A;  4ZW9 A;  5D58 A;  4LEP A;  5GXB A;  4JRE A;  4QIQ A;  2CFP A;  1PV7 A;  5EQG A;  4JA3 A;  5D6K A;  1PV6 A;  4ZWC A;  4GC0 A;  4ZWB A;  2Y5Y A;  4IKY A;  4GBY A;  5D59 A;  1PW4 A;  4IU8 A;  4YB9 D;  4TPG A;  4U4W A;  4UVM A;  3WDO A;  3O7P A;  4U4V A;  4JR9 A;  4D2D A;  2CFQ A;  4XNJ A;  4IKZ A;  5A2N A;  4IU9 A;  5EQI A;  4XNI A;  4D2B A;  4TPH A;  4YBQ A;  4ZYR A;  4J05 A;  4APS A;  4W6V A;  4PYP A;  4Q65 A;  5EQH A;  4U4T A;  2XUT A;  4IKW A;  4LDS A;  5A2O A;  4OAA A;  4GBZ A;  4TPJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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