4ZWCA

Crystal structure of maltose-bound human glut3 in the outward-open conformation at 2.6 angstrom
Total Genus 197
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
197
sequence length
468
structure length
468
Chain Sequence
TQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFITKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of ligand recognition and transport by glucose transporters
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Solute carrier family 2, facilitated glucose transporter mem
total genus 197
structure length 468
sequence length 468
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4zwcA00
3O7PA 4J05A 4GC0A 4TPGA 5D58A 4GBYA 4U4TA 4W6VA 5C65A 4JR9A 4D2CA 1PV7A 4U4WA 4U4VA 4D2BA 2XUTA 2Y5YA 5A2NA 4TPHA 2CFPA 4IKVA 4YB9D 4PYPA 4IU9A 4LDSA 4LEPA 5EQGA 1PV6A 4JA3A 5A2OA 4XNIA 4IU8A 5EQHA 4OH3A 2CFQA 4QIQA 4D2DA 4IKXA 4Q65A 3O7QA 4IKYA 4APSA 2V8NA 4ZW9A 5GXBA 4XNJA 4TPJA 4IKZA 4ZWCA 4OAAA 3WDOA 4IKWA 5EQIA 1PW4A 4ZYRA 5D59A 4UVMA 4JREA 5D6KA 4YBQA 4ZWBA 4GBZA
chains in the Genus database with same CATH superfamily
2O26A 4PS4A 3LB6A 1PVHB 4W6VA 5FHXA 1RW5A 4D2CA 4A3ID 1HUWA 2O6IA 4X51A 5KNHI 4J4LC 4O9HA 5IYDD 2XQBA 4A3KD 4JREA 3HOYD 4GS7A 2B5IA 4GBYA 1PY2A 1ETEA 1JLIA 4U4VA 4YPGC 2HYMB 4IKVA 2JA6D 3N06A 3OQ3A 5EQHA 5D28B 5D72A 3EW3A 3WCYI 3OG4A 4ZWBA 1VLKA 3S9DA 1Z7CA 3INKC 2Z3RA 3VA2A 4A3ED 5C65A 2B90A 4YDYI 3UF2A 1CNT1 5E4EA 1M49A 1PV6A 1BBNA 2Q7NB 5TS9A 3FKID 3SE4B 3QB7A 1EKUA 1ILKA 2L3YA 2V8NA 4YQXA 4NI9A 4UVMA 4A3JD 4ZF7A 3IRHA 1D9CA 1Y14A 5A2NA 3G9VB 4IU9A 1EMRA 2B8ZA 1KF9A 2CFQA 1FG9A 4GRWA 4ZW9A 1ITIA 3BPOA 5EQIA 2LAGA 4CNIC 4ZYRA 1PGRA 3NCEA 1IJZA 1HGUA 5IYBD 1ITLA 2D48A 1HULA 1RFBA 4XNIA 3D87A 3DUHC 1M4RA 1P9MB 4APSA 3G6DA 1HIJA 3HOXD 3BPLA 2B8UA 4BXXD 3B5KA 4DOHA 1F6FA 1J7VL 3PO3D 4NI7A 3HMXB 1N1FA 2XUTA 1NBPA 1A7MA 4Z5RD 5C7XA 4LEPA 2JA8D 3OG6A 5A2OA 3EJJA 4EXNA 4OH3A 4IKZA 3PIWA 1AU1A 1RHGA 4IKWA 3I4MD 4YUEC 5D22A 4DKFA 5LQBA 3O7PA 2JA7D 3PO2D 1Y6KL 3HOZD 5IP7D 1SCFA 4D2DA 1WCMD 5D70A 1HWHA 3TGXB 1HIKA 4BBSD 4WRLB 4MHLA 4Q65A 2GMFA 4A3LD 4A3DD 1PV7A 3HOVD 2R7ZD 4NKQC 1Y1WD 1INRA 1AXIA 4TPJA 5D59A 1IRLA 4GBZA 4J05A 1IK0A 4TPGA 1GNCA 2B8XA 4TPHA 4LDSA 1GA3A 4BY7D 3L5WI 1CN4C 2D9QA 1BCNA 1ITFA 3WDOA 4FA8E 1EVSA 3HHCA 4I77Z 5C3ED 1Y6ML 2B8YA 2Y5YA 2B91A 2Z3QA 1YKBA 1V7MV 1CSGA 2OQPA 3DGCL 2Q98A 4NN7A 4NN6A 1Y1VD 4BY1D 1WU3I 4DKCA 4A93D 3QWRB 3UX9A 2B63D 5FLMD 1V7NV 4A3CD 2Q14A 5D58A 3BESL 1LKIA 1D9GA 4EXPA 3N0PA 4YB9D 2KZ1A 4PYPA 5C4XD 4A3FD 2IL6A 1LK3A 1I1RB 1M4CA 2C35A 1M4AA 3DI3A 4ZS7A 4DKDA 2JA5D 4A3GD 1BGCA 3QB1A 4RS1A 2L3OA 4NN5A 4D2BA 4LRLA 3I4ND 3NCBA 2PSMA 1BGDA 3MZGA 4IU8A 1PW6A 1M47A 4A3BD 3D48P 4BBRD 1IARA 1FYHA 5IYCD 3NCFA 1ITMA 2LMSA 3HOWD 2R92D 4JR9A 1AX8A 4U4WA 3DLQI 4A3MD 3H0GD 3LB6B 3QT2C 1M4BA 3UF5A 5IP9D 4NEJA 1CYLA 1QVNA 1ALUA 4IKXA 3QAZA 1PW4A 3H3VE 1Z92A 3SE3B 4U4TA 2CYKA 2O27A 1HWGA 2H24A 3PIVA 4QIQA 2E9WC 4IKYA 1LQSL 1BUYA 1HZIA 5GXBA 4XNJA 3L5XA 2INTA 1A22A 1B5LA 1IL6A 3DI2A 2ERJD 5D6KA 1EXZA 1F45B 3D85C 1EERA 2CFPA 3UEZE 2ILKA 5EQGA 3HOUD 2R93D 1BGEA 3O7QA 4ZWCA 3Q1SI 4OAAA 4O6KA 5D71A 1CD9A 3AYHA 1Y6NL 5L6YC 4NEMA 4GC0A 5C44D 4DKEA 3NCCA 2VUMD 5FUCA 1BP3A 1RCBA 4JA3A 1M48A 3BPNA 3HHRA 4YBQA 3NPZA
chains in the Genus database with same CATH topology
3O7PA 4J05A 4GC0A 4TPGA 5D58A 4GBYA 4U4TA 4W6VA 5C65A 4JR9A 4D2CA 1PV7A 4U4WA 4U4VA 4D2BA 2XUTA 2Y5YA 5A2NA 4TPHA 2CFPA 4IKVA 4YB9D 4PYPA 4IU9A 4LDSA 4LEPA 5EQGA 1PV6A 4JA3A 5A2OA 4XNIA 4IU8A 5EQHA 4OH3A 2CFQA 4QIQA 4D2DA 4IKXA 4Q65A 3O7QA 4IKYA 4APSA 2V8NA 4ZW9A 5GXBA 4XNJA 4TPJA 4IKZA 4ZWCA 4OAAA 3WDOA 4IKWA 5EQIA 1PW4A 4ZYRA 5D59A 4UVMA 4JREA 5D6KA 4YBQA 4ZWBA 4GBZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O7P A;  4J05 A;  4GC0 A;  4TPG A;  5D58 A;  4GBY A;  4U4T A;  4W6V A;  5C65 A;  4JR9 A;  4D2C A;  1PV7 A;  4U4W A;  4U4V A;  4D2B A;  2XUT A;  2Y5Y A;  5A2N A;  4TPH A;  2CFP A;  4IKV A;  4YB9 D;  4PYP A;  4IU9 A;  4LDS A;  4LEP A;  5EQG A;  1PV6 A;  4JA3 A;  5A2O A;  4XNI A;  4IU8 A;  5EQH A;  4OH3 A;  2CFQ A;  4QIQ A;  4D2D A;  4IKX A;  4Q65 A;  3O7Q A;  4IKY A;  4APS A;  2V8N A;  4ZW9 A;  5GXB A;  4XNJ A;  4TPJ A;  4IKZ A;  4ZWC A;  4OAA A;  3WDO A;  4IKW A;  5EQI A;  1PW4 A;  4ZYR A;  5D59 A;  4UVM A;  4JRE A;  5D6K A;  4YBQ A;  4ZWB A;  4GBZ A; 
#chains in the Genus database with same CATH topology
 2O26 A;  4PS4 A;  3LB6 A;  1PVH B;  4W6V A;  5FHX A;  1RW5 A;  4D2C A;  4A3I D;  1HUW A;  2O6I A;  4X51 A;  5KNH I;  4J4L C;  4O9H A;  5IYD D;  2XQB A;  4A3K D;  4JRE A;  3HOY D;  4GS7 A;  2B5I A;  4GBY A;  1PY2 A;  1ETE A;  1JLI A;  4U4V A;  4YPG C;  2HYM B;  4IKV A;  2JA6 D;  3N06 A;  3OQ3 A;  5EQH A;  5D28 B;  5D72 A;  3EW3 A;  3WCY I;  3OG4 A;  4ZWB A;  1VLK A;  3S9D A;  1Z7C A;  3INK C;  2Z3R A;  3VA2 A;  4A3E D;  5C65 A;  2B90 A;  4YDY I;  3UF2 A;  1CNT 1;  5E4E A;  1M49 A;  1PV6 A;  1BBN A;  2Q7N B;  5TS9 A;  3FKI D;  3SE4 B;  3QB7 A;  1EKU A;  1ILK A;  2L3Y A;  2V8N A;  4YQX A;  4NI9 A;  4UVM A;  4A3J D;  4ZF7 A;  3IRH A;  1D9C A;  1Y14 A;  5A2N A;  3G9V B;  4IU9 A;  1EMR A;  2B8Z A;  1KF9 A;  2CFQ A;  1FG9 A;  4GRW A;  4ZW9 A;  1ITI A;  3BPO A;  5EQI A;  2LAG A;  4CNI C;  4ZYR A;  1PGR A;  3NCE A;  1IJZ A;  1HGU A;  5IYB D;  1ITL A;  2D48 A;  1HUL A;  1RFB A;  4XNI A;  3D87 A;  3DUH C;  1M4R A;  1P9M B;  4APS A;  3G6D A;  1HIJ A;  3HOX D;  3BPL A;  2B8U A;  4BXX D;  3B5K A;  4DOH A;  1F6F A;  1J7V L;  3PO3 D;  4NI7 A;  3HMX B;  1N1F A;  2XUT A;  1NBP A;  1A7M A;  4Z5R D;  5C7X A;  4LEP A;  2JA8 D;  3OG6 A;  5A2O A;  3EJJ A;  4EXN A;  4OH3 A;  4IKZ A;  3PIW A;  1AU1 A;  1RHG A;  4IKW A;  3I4M D;  4YUE C;  5D22 A;  4DKF A;  5LQB A;  3O7P A;  2JA7 D;  3PO2 D;  1Y6K L;  3HOZ D;  5IP7 D;  1SCF A;  4D2D A;  1WCM D;  5D70 A;  1HWH A;  3TGX B;  1HIK A;  4BBS D;  4WRL B;  4MHL A;  4Q65 A;  2GMF A;  4A3L D;  4A3D D;  1PV7 A;  3HOV D;  2R7Z D;  4NKQ C;  1Y1W D;  1INR A;  1AXI A;  4TPJ A;  5D59 A;  1IRL A;  4GBZ A;  4J05 A;  1IK0 A;  4TPG A;  1GNC A;  2B8X A;  4TPH A;  4LDS A;  1GA3 A;  4BY7 D;  3L5W I;  1CN4 C;  2D9Q A;  1BCN A;  1ITF A;  3WDO A;  4FA8 E;  1EVS A;  3HHC A;  4I77 Z;  5C3E D;  1Y6M L;  2B8Y A;  2Y5Y A;  2B91 A;  2Z3Q A;  1YKB A;  1V7M V;  1CSG A;  2OQP A;  3DGC L;  2Q98 A;  4NN7 A;  4NN6 A;  1Y1V D;  4BY1 D;  1WU3 I;  4DKC A;  4A93 D;  3QWR B;  3UX9 A;  2B63 D;  5FLM D;  1V7N V;  4A3C D;  2Q14 A;  5D58 A;  3BES L;  1LKI A;  1D9G A;  4EXP A;  3N0P A;  4YB9 D;  2KZ1 A;  4PYP A;  5C4X D;  4A3F D;  2IL6 A;  1LK3 A;  1I1R B;  1M4C A;  2C35 A;  1M4A A;  3DI3 A;  4ZS7 A;  4DKD A;  2JA5 D;  4A3G D;  1BGC A;  3QB1 A;  4RS1 A;  2L3O A;  4NN5 A;  4D2B A;  4LRL A;  3I4N D;  3NCB A;  2PSM A;  1BGD A;  3MZG A;  4IU8 A;  1PW6 A;  1M47 A;  4A3B D;  3D48 P;  4BBR D;  1IAR A;  1FYH A;  5IYC D;  3NCF A;  1ITM A;  2LMS A;  3HOW D;  2R92 D;  4JR9 A;  1AX8 A;  4U4W A;  3DLQ I;  4A3M D;  3H0G D;  3LB6 B;  3QT2 C;  1M4B A;  3UF5 A;  5IP9 D;  4NEJ A;  1CYL A;  1QVN A;  1ALU A;  4IKX A;  3QAZ A;  1PW4 A;  3H3V E;  1Z92 A;  3SE3 B;  4U4T A;  2CYK A;  2O27 A;  1HWG A;  2H24 A;  3PIV A;  4QIQ A;  2E9W C;  4IKY A;  1LQS L;  1BUY A;  1HZI A;  5GXB A;  4XNJ A;  3L5X A;  2INT A;  1A22 A;  1B5L A;  1IL6 A;  3DI2 A;  2ERJ D;  5D6K A;  1EXZ A;  1F45 B;  3D85 C;  1EER A;  2CFP A;  3UEZ E;  2ILK A;  5EQG A;  3HOU D;  2R93 D;  1BGE A;  3O7Q A;  4ZWC A;  3Q1S I;  4OAA A;  4O6K A;  5D71 A;  1CD9 A;  3AYH A;  1Y6N L;  5L6Y C;  4NEM A;  4GC0 A;  5C44 D;  4DKE A;  3NCC A;  2VUM D;  5FUC A;  1BP3 A;  1RCB A;  4JA3 A;  1M48 A;  3BPN A;  3HHR A;  4YBQ A;  3NPZ A; 
#chains in the Genus database with same CATH homology
 3O7P A;  4J05 A;  4GC0 A;  4TPG A;  5D58 A;  4GBY A;  4U4T A;  4W6V A;  5C65 A;  4JR9 A;  4D2C A;  1PV7 A;  4U4W A;  4U4V A;  4D2B A;  2XUT A;  2Y5Y A;  5A2N A;  4TPH A;  2CFP A;  4IKV A;  4YB9 D;  4PYP A;  4IU9 A;  4LDS A;  4LEP A;  5EQG A;  1PV6 A;  4JA3 A;  5A2O A;  4XNI A;  4IU8 A;  5EQH A;  4OH3 A;  2CFQ A;  4QIQ A;  4D2D A;  4IKX A;  4Q65 A;  3O7Q A;  4IKY A;  4APS A;  2V8N A;  4ZW9 A;  5GXB A;  4XNJ A;  4TPJ A;  4IKZ A;  4ZWC A;  4OAA A;  3WDO A;  4IKW A;  5EQI A;  1PW4 A;  4ZYR A;  5D59 A;  4UVM A;  4JRE A;  5D6K A;  4YBQ A;  4ZWB A;  4GBZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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