4ZYR | Genus

Total Genus 136

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	136
sequence length	403
structure length	387
Chain Sequence	NTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTWIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTDAFSLKLALELFRQPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFWYVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSL

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transport protein
source organism	Escherichia coli (strain k12)
publication title	Structure of LacY with an alpha-substituted galactoside: Connecting the binding site to the protonation site. pubmed doi rcsb
molecule keywords	Lactose permease
total genus	136
structure length	387
sequence length	403
chains with identical sequence	B
ec nomenclature
pdb deposition date	2015-05-22

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01306	LacY_symp	LacY proton/sugar symporter

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.1250.20	Mainly Alpha	Up-down Bundle	Growth Hormone; Chain: A;	MFS general substrate transporter like domains	4zyrA02
1.20.1250.20	Mainly Alpha	Up-down Bundle	Growth Hormone; Chain: A;	MFS general substrate transporter like domains	4zyrA01

2V8NA 4TPJA 4LDSA 2Y5YA 4U4WA 1PV7A 4J05A 2XUTA 4ZYRA 4OH3A 4ZWBA 4IKXA 2CFPA 4QIQA 5GXBA 3O7PA 4OAAA 4U4VA 5EQGA 4D2DA 4IKZA 5D59A 4XNIA 4LEPA 4ZWCA 4PYPA 4JREA 4Q65A 4UVMA 4D2BA 4YB9D 4D2CA 4IU8A 4IKVA 1PV6A 5D6KA 5D58A 4GBZA 4GBYA 2CFQA 3WDOA 4TPGA 5EQIA 4U4TA 1PW4A 4ZW9A 5A2OA 4TPHA 3O7QA 4JA3A 5EQHA 5C65A 4IKYA 4W6VA 4YBQA 4XNJA 4APSA 5A2NA 4IKWA 4JR9A 4GC0A 4IU9A
chains in the Genus database with same CATH superfamily

4EXNA 4ZYRA 3I4ND 4J05A 1RFBA 2INTA 4YQXA 3HHCA 4NI7A 1ITMA 4A3LD 2Q98A 4YPGC 5IP7D 4IKYA 2PSMA 4O6KA 3NPZA 4DKEA 1CD9A 3DGCL 2XUTA 3UEZE 3BESL 1EKUA 4A3BD 4D2DA 4D2BA 2O27A 3QAZA 4NKQC 5IYBD 4NN5A 1BCNA 1VLKA 1BGCA 2R7ZD 3LB6B 1KF9A 4I77Z 1HWGA 4A3GD 1Z92A 2B91A 4WRLB 5FLMD 4PS4A 4A3MD 4A93D 2GMFA 3VA2A 3O7PA 2L3YA 3SE3B 2JA5D 4XNIA 3PO3D 2H24A 1RHGA 1Y1WD 2Z3RA 4BXXD 5IP9D 2JA7D 2O26A 5C44D 4ZS7A 2B8YA 5FUCA 3QB1A 3PIWA 2Z3QA 5FHXA 5KNHI 1B5LA 3NCFA 1BUYA 4YUEC 4JREA 1V7MV 4Q65A 3OG4A 3DI3A 2B63D 2ERJD 3PO2D 1WU3I 4ZW9A 1PW4A 4RS1A 2HYMB 3UX9A 3INKC 5C4XD 1D9CA 1LQSL 1M49A 4NEMA 5D22A 5GXBA 4UVMA 5D71A 2CFQA 3OG6A 5D28B 1M47A 4W6VA 1V7NV 4XNJA 4BBRD 3HOWD 4O9HA 1YKBA 4ZF7A 1HULA 1GA3A 3HOXD 3HOZD 4GBYA 1EMRA 3UF2A 4EXPA 2B8XA 1P9MB 4YBQA 1WCMD 1GNCA 2CYKA 4JR9A 2L3OA 5C3ED 3DUHC 4NN6A 4ZWBA 1F6FA 3G9VB 3DLQI 2JA6D 1Z7CA 4IKZA 3EW3A 1HIJA 2Q7NB 3AYHA 3D85C 2JA8D 1HZIA 1JLIA 2Y5YA 1EERA 1FG9A 1Y6NL 1IJZA 1CYLA 2CFPA 4BY7D 2E9WC 4YB9D 3DI2A 4BBSD 4DKDA 3I4MD 2O6IA 4TPGA 1HIKA 2R93D 5EQHA 3NCBA 1CN4C 1M48A 2LMSA 1NBPA 4DKFA 3BPOA 4TPJA 1BGEA 3G6DA 3D48P 2LAGA 5D70A 4FA8E 4IKXA 1PGRA 3PIVA 1EXZA 4U4VA 1AXIA 1HUWA 3Q1SI 1IL6A 1N1FA 1I1RB 3L5XA 1A22A 4IKVA 3FKID 4GBZA 3N06A 5A2NA 5IYCD 1BGDA 1ITFA 1PY2A 1M4RA 1LKIA 4A3ID 3HOUD 4OH3A 4NN7A 2B90A 4X51A 5C7XA 4PYPA 1QVNA 4IU8A 5L6YC 1RW5A 1FYHA 4DKCA 1LK3A 5LQBA 3QT2C 4J4LC 4NEJA 2D48A 1RCBA 5D59A 4NI9A 3OQ3A 2B8ZA 4BY1D 1Y6KL 3SE4B 3BPLA 5A2OA 4GRWA 3HHRA 4CNIC 3QB7A 1Y14A 3HMXB 4A3JD 1IRLA 2V8NA 3L5WI 1INRA 2R92D 1ALUA 3HOVD 3B5KA 3BPNA 2B5IA 4A3CD 4U4TA 3O7QA 4IU9A 1M4AA 4LDSA 1BBNA 3HOYD 5TS9A 3N0PA 2VUMD 1D9GA 4QIQA 3NCEA 4OAAA 1AU1A 1AX8A 3NCCA 3H0GD 4A3FD 4LEPA 1CNT1 5E4EA 4DOHA 3LB6A 1M4BA 2Q14A 3EJJA 2IL6A 1Y1VD 1PV7A 4MHLA 1ILKA 3MZGA 3IRHA 4LRLA 1PW6A 3WCYI 1SCFA 4ZWCA 1BP3A 4A3DD 4GS7A 1PV6A 5D6KA 1F45B 3UF5A 5EQIA 1HGUA 4JA3A 4IKWA 4GC0A 4Z5RD 3H3VE 4U4WA 5IYDD 1HWHA 2C35A 2B8UA 2ILKA 5EQGA 1EVSA 3QWRB 1IK0A 1ITIA 3D87A 1ETEA 5C65A 1ITLA 4APSA 2OQPA 3S9DA 1CSGA 4YDYI 2XQBA 4A3KD 1PVHB 4D2CA 1Y6ML 4A3ED 1A7MA 2KZ1A 5D58A 3TGXB 3WDOA 5D72A 4TPHA 1M4CA 2D9QA 1IARA 1J7VL
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2V8N A;  4TPJ A;  4LDS A;  2Y5Y A;  4U4W A;  1PV7 A;  4J05 A;  2XUT A;  4ZYR A;  4OH3 A;  4ZWB A;  4IKX A;  2CFP A;  4QIQ A;  5GXB A;  3O7P A;  4OAA A;  4U4V A;  5EQG A;  4D2D A;  4IKZ A;  5D59 A;  4XNI A;  4LEP A;  4ZWC A;  4PYP A;  4JRE A;  4Q65 A;  4UVM A;  4D2B A;  4YB9 D;  4D2C A;  4IU8 A;  4IKV A;  1PV6 A;  5D6K A;  5D58 A;  4GBZ A;  4GBY A;  2CFQ A;  3WDO A;  4TPG A;  5EQI A;  4U4T A;  1PW4 A;  4ZW9 A;  5A2O A;  4TPH A;  3O7Q A;  4JA3 A;  5EQH A;  5C65 A;  4IKY A;  4W6V A;  4YBQ A;  4XNJ A;  4APS A;  5A2N A;  4IKW A;  4JR9 A;  4GC0 A;  4IU9 A; 
#chains in the Genus database with same CATH topology
 4EXN A;  4ZYR A;  3I4N D;  4J05 A;  1RFB A;  2INT A;  4YQX A;  3HHC A;  4NI7 A;  1ITM A;  4A3L D;  2Q98 A;  4YPG C;  5IP7 D;  4IKY A;  2PSM A;  4O6K A;  3NPZ A;  4DKE A;  1CD9 A;  3DGC L;  2XUT A;  3UEZ E;  3BES L;  1EKU A;  4A3B D;  4D2D A;  4D2B A;  2O27 A;  3QAZ A;  4NKQ C;  5IYB D;  4NN5 A;  1BCN A;  1VLK A;  1BGC A;  2R7Z D;  3LB6 B;  1KF9 A;  4I77 Z;  1HWG A;  4A3G D;  1Z92 A;  2B91 A;  4WRL B;  5FLM D;  4PS4 A;  4A3M D;  4A93 D;  2GMF A;  3VA2 A;  3O7P A;  2L3Y A;  3SE3 B;  2JA5 D;  4XNI A;  3PO3 D;  2H24 A;  1RHG A;  1Y1W D;  2Z3R A;  4BXX D;  5IP9 D;  2JA7 D;  2O26 A;  5C44 D;  4ZS7 A;  2B8Y A;  5FUC A;  3QB1 A;  3PIW A;  2Z3Q A;  5FHX A;  5KNH I;  1B5L A;  3NCF A;  1BUY A;  4YUE C;  4JRE A;  1V7M V;  4Q65 A;  3OG4 A;  3DI3 A;  2B63 D;  2ERJ D;  3PO2 D;  1WU3 I;  4ZW9 A;  1PW4 A;  4RS1 A;  2HYM B;  3UX9 A;  3INK C;  5C4X D;  1D9C A;  1LQS L;  1M49 A;  4NEM A;  5D22 A;  5GXB A;  4UVM A;  5D71 A;  2CFQ A;  3OG6 A;  5D28 B;  1M47 A;  4W6V A;  1V7N V;  4XNJ A;  4BBR D;  3HOW D;  4O9H A;  1YKB A;  4ZF7 A;  1HUL A;  1GA3 A;  3HOX D;  3HOZ D;  4GBY A;  1EMR A;  3UF2 A;  4EXP A;  2B8X A;  1P9M B;  4YBQ A;  1WCM D;  1GNC A;  2CYK A;  4JR9 A;  2L3O A;  5C3E D;  3DUH C;  4NN6 A;  4ZWB A;  1F6F A;  3G9V B;  3DLQ I;  2JA6 D;  1Z7C A;  4IKZ A;  3EW3 A;  1HIJ A;  2Q7N B;  3AYH A;  3D85 C;  2JA8 D;  1HZI A;  1JLI A;  2Y5Y A;  1EER A;  1FG9 A;  1Y6N L;  1IJZ A;  1CYL A;  2CFP A;  4BY7 D;  2E9W C;  4YB9 D;  3DI2 A;  4BBS D;  4DKD A;  3I4M D;  2O6I A;  4TPG A;  1HIK A;  2R93 D;  5EQH A;  3NCB A;  1CN4 C;  1M48 A;  2LMS A;  1NBP A;  4DKF A;  3BPO A;  4TPJ A;  1BGE A;  3G6D A;  3D48 P;  2LAG A;  5D70 A;  4FA8 E;  4IKX A;  1PGR A;  3PIV A;  1EXZ A;  4U4V A;  1AXI A;  1HUW A;  3Q1S I;  1IL6 A;  1N1F A;  1I1R B;  3L5X A;  1A22 A;  4IKV A;  3FKI D;  4GBZ A;  3N06 A;  5A2N A;  5IYC D;  1BGD A;  1ITF A;  1PY2 A;  1M4R A;  1LKI A;  4A3I D;  3HOU D;  4OH3 A;  4NN7 A;  2B90 A;  4X51 A;  5C7X A;  4PYP A;  1QVN A;  4IU8 A;  5L6Y C;  1RW5 A;  1FYH A;  4DKC A;  1LK3 A;  5LQB A;  3QT2 C;  4J4L C;  4NEJ A;  2D48 A;  1RCB A;  5D59 A;  4NI9 A;  3OQ3 A;  2B8Z A;  4BY1 D;  1Y6K L;  3SE4 B;  3BPL A;  5A2O A;  4GRW A;  3HHR A;  4CNI C;  3QB7 A;  1Y14 A;  3HMX B;  4A3J D;  1IRL A;  2V8N A;  3L5W I;  1INR A;  2R92 D;  1ALU A;  3HOV D;  3B5K A;  3BPN A;  2B5I A;  4A3C D;  4U4T A;  3O7Q A;  4IU9 A;  1M4A A;  4LDS A;  1BBN A;  3HOY D;  5TS9 A;  3N0P A;  2VUM D;  1D9G A;  4QIQ A;  3NCE A;  4OAA A;  1AU1 A;  1AX8 A;  3NCC A;  3H0G D;  4A3F D;  4LEP A;  1CNT 1;  5E4E A;  4DOH A;  3LB6 A;  1M4B A;  2Q14 A;  3EJJ A;  2IL6 A;  1Y1V D;  1PV7 A;  4MHL A;  1ILK A;  3MZG A;  3IRH A;  4LRL A;  1PW6 A;  3WCY I;  1SCF A;  4ZWC A;  1BP3 A;  4A3D D;  4GS7 A;  1PV6 A;  5D6K A;  1F45 B;  3UF5 A;  5EQI A;  1HGU A;  4JA3 A;  4IKW A;  4GC0 A;  4Z5R D;  3H3V E;  4U4W A;  5IYD D;  1HWH A;  2C35 A;  2B8U A;  2ILK A;  5EQG A;  1EVS A;  3QWR B;  1IK0 A;  1ITI A;  3D87 A;  1ETE A;  5C65 A;  1ITL A;  4APS A;  2OQP A;  3S9D A;  1CSG A;  4YDY I;  2XQB A;  4A3K D;  1PVH B;  4D2C A;  1Y6M L;  4A3E D;  1A7M A;  2KZ1 A;  5D58 A;  3TGX B;  3WDO A;  5D72 A;  4TPH A;  1M4C A;  2D9Q A;  1IAR A;  1J7V L; 
#chains in the Genus database with same CATH homology
 2V8N A;  4TPJ A;  4LDS A;  2Y5Y A;  4U4W A;  1PV7 A;  4J05 A;  2XUT A;  4ZYR A;  4OH3 A;  4ZWB A;  4IKX A;  2CFP A;  4QIQ A;  5GXB A;  3O7P A;  4OAA A;  4U4V A;  5EQG A;  4D2D A;  4IKZ A;  5D59 A;  4XNI A;  4LEP A;  4ZWC A;  4PYP A;  4JRE A;  4Q65 A;  4UVM A;  4D2B A;  4YB9 D;  4D2C A;  4IU8 A;  4IKV A;  1PV6 A;  5D6K A;  5D58 A;  4GBZ A;  4GBY A;  2CFQ A;  3WDO A;  4TPG A;  5EQI A;  4U4T A;  1PW4 A;  4ZW9 A;  5A2O A;  4TPH A;  3O7Q A;  4JA3 A;  5EQH A;  5C65 A;  4IKY A;  4W6V A;  4YBQ A;  4XNJ A;  4APS A;  5A2N A;  4IKW A;  4JR9 A;  4GC0 A;  4IU9 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4ZYRA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations