4A3BD

Rna polymerase ii initial transcribing complex with a 4nt dna-rna hybrid
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
219
structure length
178
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 50
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4a3bD02
4A3ID 4A3GD 4A3JD 3PO2D 3I4ND 2R93D 4BY1D 4A3LD 3I4MD 4BY7D 3H3VE 2R7ZD 5IP9D 4A3MD 3HOXD 3FKID 5C3ED 2C35A 4A3FD 3HOVD 3HOUD 4BBRD 4BBSD 5IYCD 4A3CD 4A93D 5C4XD 4BXXD 4A3ED 2B63D 1WCMD 5IYBD 1Y1WD 3AYHA 2JA6D 2JA8D 3HOZD 4A3KD 5FLMD 1Y14A 2R92D 3HOWD 2VUMD 2JA5D 5C44D 4A3DD 5IP7D 3HOYD 3PO3D 5IYDD 4A3BD 1Y1VD 3H0GD 2JA7D
chains in the Genus database with same CATH superfamily
4A3JD 5A2OA 5IP9D 1PV6A 3OQ3A 4QIQA 4DKEA 3N0PA 4I77Z 3IRHA 3TGXB 2JA8D 1CN4C 2B90A 3L5WI 1JLIA 1EMRA 5E4EA 4ZYRA 1Z92A 4UVMA 3UF5A 4NN7A 2B8YA 1B5LA 3BPNA 1BGCA 2H24A 2IL6A 3HOXD 4A3FD 4NEMA 1ILKA 4BBSD 2XUTA 4NKQC 4A3DD 3SE4B 4A3ID 3LB6A 4FA8E 5FUCA 4D2CA 3NCCA 3NCBA 1RCBA 3DUHC 5C3ED 3UEZE 4DKFA 4D2BA 3HHCA 1ITIA 1HIKA 1CYLA 1HUWA 3HHRA 1PW6A 2B8UA 1Z7CA 3MZGA 2R7ZD 1RHGA 4W6VA 4YDYI 4GS7A 5IYCD 4J05A 2B63D 5IYBD 1PV7A 5D22A 5TS9A 1EERA 3NPZA 4GBZA 4NEJA 4D2DA 1RFBA 5LQBA 1AX8A 1M4AA 4OH3A 4WRLB 1CNT1 4TPJA 1ITLA 1GA3A 1HIJA 4YPGC 3G6DA 2O6IA 3UF2A 5GXBA 4ZS7A 5C7XA 1J7VL 3EW3A 3NCEA 1BGDA 4GC0A 1IL6A 2B8XA 4YBQA 5L6YC 4Q65A 1FG9A 1HZIA 3WCYI 4NI9A 5D58A 5D72A 4BY1D 1PW4A 1NBPA 2LMSA 1INRA 3INKC 5EQGA 1IARA 1AXIA 4A3CD 3BPLA 1Y1WD 1Y14A 1V7MV 1I1RB 3HOYD 3DGCL 1WU3I 1M47A 5IYDD 4O6KA 3G9VB 1A22A 4EXNA 4A3LD 2HYMB 3I4MD 4U4WA 2PSMA 3PIVA 4DOHA 3D87A 4IKYA 2JA6D 1FYHA 4RS1A 1ITFA 1ITMA 2XQBA 4JR9A 2Q14A 1Y1VD 2L3OA 4CNIC 3H0GD 1D9GA 2KZ1A 2CFQA 4Z5RD 4NI7A 2E9WC 4X51A 5C65A 1M48A 4A93D 4A3ED 2Z3RA 1BBNA 1BCNA 4NN5A 2Q98A 4ZF7A 1HGUA 3O7QA 4LEPA 4XNJA 5C4XD 1M49A 2Y5YA 3NCFA 3DI2A 3QAZA 1IJZA 4YUEC 3BESL 2B5IA 3AYHA 1YKBA 1CSGA 2V8NA 4DKCA 3VA2A 1ETEA 4IKZA 5EQIA 4PS4A 1Y6ML 1RW5A 4XNIA 4A3BD 4J4LC 3DLQI 2JA7D 3PO2D 1HWGA 4BY7D 1V7NV 5D59A 3HOVD 1GNCA 3QB7A 3D48P 2INTA 4JREA 4OAAA 4IU9A 1Y6KL 1F6FA 3HMXB 2ILKA 1EXZA 1VLKA 1LKIA 3EJJA 4MHLA 3I4ND 1PVHB 5D6KA 2ERJD 1F45B 3H3VE 2GMFA 1ALUA 3FKID 2C35A 3L5XA 4YB9D 1BUYA 3O7PA 4IKWA 3S9DA 4IU8A 4ZW9A 5FLMD 5A2NA 1N1FA 4LRLA 4GBYA 1A7MA 3PO3D 3LB6B 1Y6NL 1EKUA 4YQXA 4DKDA 4BBRD 2Q7NB 1M4BA 2O26A 1IRLA 1LK3A 3BPOA 1PY2A 5D70A 5C44D 2L3YA 4LDSA 1M4RA 5D71A 4TPGA 5FHXA 3DI3A 3D85C 4A3GD 1LQSL 3Q1SI 3OG6A 1BGEA 4O9HA 3HOUD 3B5KA 2CFPA 5KNHI 3HOZD 2D9QA 4APSA 2R92D 3HOWD 3WDOA 2VUMD 1AU1A 4ZWBA 3N06A 3UX9A 1KF9A 1PGRA 2Z3QA 2CYKA 5EQHA 2OQPA 3PIWA 3QB1A 4EXPA 5D28B 1EVSA 4JA3A 4A3MD 2B91A 4ZWCA 3QWRB 3QT2C 4BXXD 1CD9A 1WCMD 3SE3B 1HULA 2JA5D 1IK0A 3OG4A 1SCFA 4PYPA 5IP7D 4U4VA 2R93D 1M4CA 1P9MB 1HWHA 2LAGA 4U4TA 4A3KD 4IKXA 4TPHA 1QVNA 2O27A 4GRWA 4NN6A 1BP3A 2D48A 1D9CA 2B8ZA 4IKVA
chains in the Genus database with same CATH topology
1M4AA 1D9GA 4A3JD 2KZ1A 1EKUA 4NI7A 4YQXA 4Z5RD 5IP9D 4DKDA 3OQ3A 2E9WC 4WRLB 4X51A 4DKEA 1M48A 1CNT1 3N0PA 4I77Z 2Q7NB 4BBRD 1M4BA 4A93D 2O26A 3IRHA 1IRLA 1ITLA 1LK3A 3BPOA 3TGXB 4A3ED 1PY2A 2JA8D 1GA3A 2Z3RA 1CN4C 1BBNA 1BCNA 2B90A 4CNIC 3L5WI 5D70A 1HIJA 1JLIA 5C44D 4NN5A 4YPGC 2L3YA 3G6DA 2O6IA 1M4RA 3UF2A 1EMRA 2Q98A 4ZF7A 5D71A 1HGUA 5E4EA 5C4XD 5FHXA 3DI3A 3D85C 1Z92A 4ZS7A 1M49A 4A3GD 3UF5A 3NCFA 4NN7A 2B8YA 3DI2A 3QAZA 1B5LA 1LQSL 1BGCA 3BPNA 3Q1SI 3OG6A 2H24A 2IL6A 1BGEA 3HOXD 4A3FD 4NEMA 4O9HA 1ILKA 1IJZA 3HOUD 4BBSD 3B5KA 4YUEC 3BESL 5C7XA 1J7VL 2B5IA 3AYHA 4NKQC 5LQBA 5KNHI 1YKBA 3EW3A 3NCEA 1CSGA 2D9QA 3HOZD 2R92D 1BGDA 3HOWD 4DKCA 1IL6A 3VA2A 2VUMD 2B8XA 1AU1A 1ETEA 4A3DD 3N06A 1Y6ML 4PS4A 3UX9A 1RW5A 5L6YC 1FG9A 4A3BD 4J4LC 1KF9A 1PGRA 2Z3QA 2CYKA 3DLQI 1HZIA 3SE4B 3WCYI 4A3ID 2JA7D 3LB6A 4NI9A 4FA8E 3PO2D 1HWGA 5D72A 2OQPA 5FUCA 4BY1D 3PIWA 3QB1A 4EXPA 1NBPA 4BY7D 3NCCA 3NCBA 1V7NV 5D28B 1EVSA 1RCBA 4A3MD 3DUHC 5C3ED 2B91A 2LMSA 3HOVD 1INRA 3INKC 1GNCA 1IARA 3QB7A 1AXIA 3QWRB 3UEZE 4DKFA 4A3CD 3BPLA 3D48P 1CD9A 1WCMD 2INTA 3QT2C 1Y1WD 3SE3B 1HULA 4BXXD 3HHCA 1ITIA 1Y14A 1HIKA 2JA5D 1V7MV 1IK0A 1Y6KL 1I1RB 1SCFA 3OG4A 5IP7D 3HOYD 1F6FA 1CYLA 3HMXB 3DGCL 1WU3I 1EXZA 1VLKA 1LKIA 1M47A 2ILKA 3EJJA 4O6KA 5IYDD 1HUWA 4MHLA 3HHRA 3G9VB 1PW6A 1A22A 2B8UA 4EXNA 3I4ND 2R93D 4A3LD 1PVHB 2HYMB 3I4MD 1Z7CA 1M4CA 2ERJD 1F45B 3MZGA 3H3VE 1RHGA 2R7ZD 2GMFA 1P9MB 2PSMA 1HWHA 1ALUA 3FKID 2LAGA 2C35A 4YDYI 3PIVA 3L5XA 1BUYA 4GS7A 5IYCD 4DOHA 3D87A 3S9DA 2B63D 5IYBD 2JA6D 1FYHA 4RS1A 5FLMD 4A3KD 1ITFA 1ITMA 2XQBA 1QVNA 2O27A 5D22A 1N1FA 1EERA 4GRWA 4LRLA 4NN6A 5TS9A 1BP3A 1A7MA 2D48A 1D9CA 2Q14A 3NPZA 3LB6B 3PO3D 2B8ZA 4NEJA 1Y6NL 1Y1VD 2L3OA 1RFBA 3H0GD 1AX8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3I D;  4A3G D;  4A3J D;  3PO2 D;  3I4N D;  2R93 D;  4BY1 D;  4A3L D;  3I4M D;  4BY7 D;  3H3V E;  2R7Z D;  5IP9 D;  4A3M D;  3HOX D;  3FKI D;  5C3E D;  2C35 A;  4A3F D;  3HOV D;  3HOU D;  4BBR D;  4BBS D;  5IYC D;  4A3C D;  4A93 D;  5C4X D;  4BXX D;  4A3E D;  2B63 D;  1WCM D;  5IYB D;  1Y1W D;  3AYH A;  2JA6 D;  2JA8 D;  3HOZ D;  4A3K D;  5FLM D;  1Y14 A;  2R92 D;  3HOW D;  2VUM D;  2JA5 D;  5C44 D;  4A3D D;  5IP7 D;  3HOY D;  3PO3 D;  5IYD D;  4A3B D;  1Y1V D;  3H0G D;  2JA7 D; 
#chains in the Genus database with same CATH topology
 4A3J D;  5A2O A;  5IP9 D;  1PV6 A;  3OQ3 A;  4QIQ A;  4DKE A;  3N0P A;  4I77 Z;  3IRH A;  3TGX B;  2JA8 D;  1CN4 C;  2B90 A;  3L5W I;  1JLI A;  1EMR A;  5E4E A;  4ZYR A;  1Z92 A;  4UVM A;  3UF5 A;  4NN7 A;  2B8Y A;  1B5L A;  3BPN A;  1BGC A;  2H24 A;  2IL6 A;  3HOX D;  4A3F D;  4NEM A;  1ILK A;  4BBS D;  2XUT A;  4NKQ C;  4A3D D;  3SE4 B;  4A3I D;  3LB6 A;  4FA8 E;  5FUC A;  4D2C A;  3NCC A;  3NCB A;  1RCB A;  3DUH C;  5C3E D;  3UEZ E;  4DKF A;  4D2B A;  3HHC A;  1ITI A;  1HIK A;  1CYL A;  1HUW A;  3HHR A;  1PW6 A;  2B8U A;  1Z7C A;  3MZG A;  2R7Z D;  1RHG A;  4W6V A;  4YDY I;  4GS7 A;  5IYC D;  4J05 A;  2B63 D;  5IYB D;  1PV7 A;  5D22 A;  5TS9 A;  1EER A;  3NPZ A;  4GBZ A;  4NEJ A;  4D2D A;  1RFB A;  5LQB A;  1AX8 A;  1M4A A;  4OH3 A;  4WRL B;  1CNT 1;  4TPJ A;  1ITL A;  1GA3 A;  1HIJ A;  4YPG C;  3G6D A;  2O6I A;  3UF2 A;  5GXB A;  4ZS7 A;  5C7X A;  1J7V L;  3EW3 A;  3NCE A;  1BGD A;  4GC0 A;  1IL6 A;  2B8X A;  4YBQ A;  5L6Y C;  4Q65 A;  1FG9 A;  1HZI A;  3WCY I;  4NI9 A;  5D58 A;  5D72 A;  4BY1 D;  1PW4 A;  1NBP A;  2LMS A;  1INR A;  3INK C;  5EQG A;  1IAR A;  1AXI A;  4A3C D;  3BPL A;  1Y1W D;  1Y14 A;  1V7M V;  1I1R B;  3HOY D;  3DGC L;  1WU3 I;  1M47 A;  5IYD D;  4O6K A;  3G9V B;  1A22 A;  4EXN A;  4A3L D;  2HYM B;  3I4M D;  4U4W A;  2PSM A;  3PIV A;  4DOH A;  3D87 A;  4IKY A;  2JA6 D;  1FYH A;  4RS1 A;  1ITF A;  1ITM A;  2XQB A;  4JR9 A;  2Q14 A;  1Y1V D;  2L3O A;  4CNI C;  3H0G D;  1D9G A;  2KZ1 A;  2CFQ A;  4Z5R D;  4NI7 A;  2E9W C;  4X51 A;  5C65 A;  1M48 A;  4A93 D;  4A3E D;  2Z3R A;  1BBN A;  1BCN A;  4NN5 A;  2Q98 A;  4ZF7 A;  1HGU A;  3O7Q A;  4LEP A;  4XNJ A;  5C4X D;  1M49 A;  2Y5Y A;  3NCF A;  3DI2 A;  3QAZ A;  1IJZ A;  4YUE C;  3BES L;  2B5I A;  3AYH A;  1YKB A;  1CSG A;  2V8N A;  4DKC A;  3VA2 A;  1ETE A;  4IKZ A;  5EQI A;  4PS4 A;  1Y6M L;  1RW5 A;  4XNI A;  4A3B D;  4J4L C;  3DLQ I;  2JA7 D;  3PO2 D;  1HWG A;  4BY7 D;  1V7N V;  5D59 A;  3HOV D;  1GNC A;  3QB7 A;  3D48 P;  2INT A;  4JRE A;  4OAA A;  4IU9 A;  1Y6K L;  1F6F A;  3HMX B;  2ILK A;  1EXZ A;  1VLK A;  1LKI A;  3EJJ A;  4MHL A;  3I4N D;  1PVH B;  5D6K A;  2ERJ D;  1F45 B;  3H3V E;  2GMF A;  1ALU A;  3FKI D;  2C35 A;  3L5X A;  4YB9 D;  1BUY A;  3O7P A;  4IKW A;  3S9D A;  4IU8 A;  4ZW9 A;  5FLM D;  5A2N A;  1N1F A;  4LRL A;  4GBY A;  1A7M A;  3PO3 D;  3LB6 B;  1Y6N L;  1EKU A;  4YQX A;  4DKD A;  4BBR D;  2Q7N B;  1M4B A;  2O26 A;  1IRL A;  1LK3 A;  3BPO A;  1PY2 A;  5D70 A;  5C44 D;  2L3Y A;  4LDS A;  1M4R A;  5D71 A;  4TPG A;  5FHX A;  3DI3 A;  3D85 C;  4A3G D;  1LQS L;  3Q1S I;  3OG6 A;  1BGE A;  4O9H A;  3HOU D;  3B5K A;  2CFP A;  5KNH I;  3HOZ D;  2D9Q A;  4APS A;  2R92 D;  3HOW D;  3WDO A;  2VUM D;  1AU1 A;  4ZWB A;  3N06 A;  3UX9 A;  1KF9 A;  1PGR A;  2Z3Q A;  2CYK A;  5EQH A;  2OQP A;  3PIW A;  3QB1 A;  4EXP A;  5D28 B;  1EVS A;  4JA3 A;  4A3M D;  2B91 A;  4ZWC A;  3QWR B;  3QT2 C;  4BXX D;  1CD9 A;  1WCM D;  3SE3 B;  1HUL A;  2JA5 D;  1IK0 A;  3OG4 A;  1SCF A;  4PYP A;  5IP7 D;  4U4V A;  2R93 D;  1M4C A;  1P9M B;  1HWH A;  2LAG A;  4U4T A;  4A3K D;  4IKX A;  4TPH A;  1QVN A;  2O27 A;  4GRW A;  4NN6 A;  1BP3 A;  2D48 A;  1D9C A;  2B8Z A;  4IKV A; 
#chains in the Genus database with same CATH homology
 1M4A A;  1D9G A;  4A3J D;  2KZ1 A;  1EKU A;  4NI7 A;  4YQX A;  4Z5R D;  5IP9 D;  4DKD A;  3OQ3 A;  2E9W C;  4WRL B;  4X51 A;  4DKE A;  1M48 A;  1CNT 1;  3N0P A;  4I77 Z;  2Q7N B;  4BBR D;  1M4B A;  4A93 D;  2O26 A;  3IRH A;  1IRL A;  1ITL A;  1LK3 A;  3BPO A;  3TGX B;  4A3E D;  1PY2 A;  2JA8 D;  1GA3 A;  2Z3R A;  1CN4 C;  1BBN A;  1BCN A;  2B90 A;  4CNI C;  3L5W I;  5D70 A;  1HIJ A;  1JLI A;  5C44 D;  4NN5 A;  4YPG C;  2L3Y A;  3G6D A;  2O6I A;  1M4R A;  3UF2 A;  1EMR A;  2Q98 A;  4ZF7 A;  5D71 A;  1HGU A;  5E4E A;  5C4X D;  5FHX A;  3DI3 A;  3D85 C;  1Z92 A;  4ZS7 A;  1M49 A;  4A3G D;  3UF5 A;  3NCF A;  4NN7 A;  2B8Y A;  3DI2 A;  3QAZ A;  1B5L A;  1LQS L;  1BGC A;  3BPN A;  3Q1S I;  3OG6 A;  2H24 A;  2IL6 A;  1BGE A;  3HOX D;  4A3F D;  4NEM A;  4O9H A;  1ILK A;  1IJZ A;  3HOU D;  4BBS D;  3B5K A;  4YUE C;  3BES L;  5C7X A;  1J7V L;  2B5I A;  3AYH A;  4NKQ C;  5LQB A;  5KNH I;  1YKB A;  3EW3 A;  3NCE A;  1CSG A;  2D9Q A;  3HOZ D;  2R92 D;  1BGD A;  3HOW D;  4DKC A;  1IL6 A;  3VA2 A;  2VUM D;  2B8X A;  1AU1 A;  1ETE A;  4A3D D;  3N06 A;  1Y6M L;  4PS4 A;  3UX9 A;  1RW5 A;  5L6Y C;  1FG9 A;  4A3B D;  4J4L C;  1KF9 A;  1PGR A;  2Z3Q A;  2CYK A;  3DLQ I;  1HZI A;  3SE4 B;  3WCY I;  4A3I D;  2JA7 D;  3LB6 A;  4NI9 A;  4FA8 E;  3PO2 D;  1HWG A;  5D72 A;  2OQP A;  5FUC A;  4BY1 D;  3PIW A;  3QB1 A;  4EXP A;  1NBP A;  4BY7 D;  3NCC A;  3NCB A;  1V7N V;  5D28 B;  1EVS A;  1RCB A;  4A3M D;  3DUH C;  5C3E D;  2B91 A;  2LMS A;  3HOV D;  1INR A;  3INK C;  1GNC A;  1IAR A;  3QB7 A;  1AXI A;  3QWR B;  3UEZ E;  4DKF A;  4A3C D;  3BPL A;  3D48 P;  1CD9 A;  1WCM D;  2INT A;  3QT2 C;  1Y1W D;  3SE3 B;  1HUL A;  4BXX D;  3HHC A;  1ITI A;  1Y14 A;  1HIK A;  2JA5 D;  1V7M V;  1IK0 A;  1Y6K L;  1I1R B;  1SCF A;  3OG4 A;  5IP7 D;  3HOY D;  1F6F A;  1CYL A;  3HMX B;  3DGC L;  1WU3 I;  1EXZ A;  1VLK A;  1LKI A;  1M47 A;  2ILK A;  3EJJ A;  4O6K A;  5IYD D;  1HUW A;  4MHL A;  3HHR A;  3G9V B;  1PW6 A;  1A22 A;  2B8U A;  4EXN A;  3I4N D;  2R93 D;  4A3L D;  1PVH B;  2HYM B;  3I4M D;  1Z7C A;  1M4C A;  2ERJ D;  1F45 B;  3MZG A;  3H3V E;  1RHG A;  2R7Z D;  2GMF A;  1P9M B;  2PSM A;  1HWH A;  1ALU A;  3FKI D;  2LAG A;  2C35 A;  4YDY I;  3PIV A;  3L5X A;  1BUY A;  4GS7 A;  5IYC D;  4DOH A;  3D87 A;  3S9D A;  2B63 D;  5IYB D;  2JA6 D;  1FYH A;  4RS1 A;  5FLM D;  4A3K D;  1ITF A;  1ITM A;  2XQB A;  1QVN A;  2O27 A;  5D22 A;  1N1F A;  1EER A;  4GRW A;  4LRL A;  4NN6 A;  5TS9 A;  1BP3 A;  1A7M A;  2D48 A;  1D9C A;  2Q14 A;  3NPZ A;  3LB6 B;  3PO3 D;  2B8Z A;  4NEJ A;  1Y6N L;  1Y1V D;  2L3O A;  1RFB A;  3H0G D;  1AX8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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