4A3DD

Rna polymerase ii initial transcribing complex with a 6nt dna-rna hybrid
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
219
structure length
178
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 52
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4a3dD02
3I4ND 5IYDD 4BY1D 5IYCD 3I4MD 4BBSD 1Y1WD 2C35A 2R93D 4BXXD 5IP7D 3H0GD 4A93D 2JA8D 4A3MD 3HOWD 5FLMD 3PO2D 1Y14A 5C44D 3HOXD 4A3GD 2B63D 2VUMD 4A3DD 4A3LD 1WCMD 2JA6D 1Y1VD 4A3CD 5C3ED 3AYHA 2JA5D 4A3JD 3H3VE 2R92D 5IYBD 5IP9D 2R7ZD 3HOZD 3HOYD 4A3FD 4BBRD 3PO3D 4A3ID 2JA7D 4A3ED 3HOUD 4A3BD 4A3KD 3HOVD 4BY7D 5C4XD 3FKID
chains in the Genus database with same CATH superfamily
5E4EA 4GS7A 1HWGA 1IARA 3D85C 1AXIA 3OG6A 4JREA 4A3GD 2JA6D 3NCCA 3H3VE 1J7VL 4TPGA 4DKFA 2PSMA 4J4LC 1BUYA 1CYLA 4Q65A 1A22A 3TGXB 3OQ3A 1RHGA 5D22A 3AYHA 1N1FA 4A3JD 2B90A 2B5IA 1ITIA 3DI3A 4MHLA 2LAGA 1D9CA 1PW4A 4TPJA 2Z3RA 1Z7CA 5C65A 1NBPA 4APSA 2CFPA 3LB6A 3VA2A 4ZW9A 3S9DA 5IP9D 1ITMA 2Q14A 2XQBA 1BGEA 3UF2A 1ITLA 2CFQA 4OAAA 4EXPA 1V7MV 2B63D 2B91A 4A3CD 4DKDA 2R92D 1F6FA 1BCNA 2H24A 3OG4A 3FKID 4BXXD 3B5KA 3WCYI 1AU1A 1AX8A 4U4VA 4A3DD 3WDOA 3SE4B 1YKBA 1PW6A 3UX9A 1FG9A 5D58A 1WU3I 1M4BA 4YBQA 4JR9A 3BESL 1PY2A 3I4MD 3H0GD 4IKWA 5EQHA 1BGCA 4J05A 4ZS7A 4ZYRA 1CSGA 3L5WI 4X51A 4NI7A 1ILKA 2JA5D 5IYBD 3DGCL 5D72A 4YQXA 4A3FD 4D2DA 1P9MB 4GBZA 4LEPA 2HYMB 3NPZA 5C7XA 1LKIA 3PO2D 3BPNA 1INRA 4IKVA 3QT2C 3HOZD 4NN5A 5GXBA 3N0PA 1HUWA 3HOVD 4WRLB 3HMXB 3Q1SI 1ALUA 4PS4A 3INKC 5C44D 4LRLA 1WCMD 1PGRA 1Y1VD 5C3ED 3NCFA 4XNIA 2O6IA 2D9QA 3HOUD 1ITFA 4RS1A 5IYCD 1HIKA 2Q7NB 2R93D 2JA8D 1EXZA 1Y14A 4ZWBA 4GRWA 5FHXA 4YB9D 3L5XA 3BPLA 1Y6ML 3G9VB 1CNT1 2CYKA 1Z92A 2O26A 4A3KD 1M4CA 1HULA 3NCEA 1D9GA 2GMFA 4A93D 5EQGA 5FLMD 3BPOA 5D71A 1FYHA 2O27A 3HHCA 5D70A 2Z3QA 3G6DA 3D87A 1PV6A 2KZ1A 1IL6A 5TS9A 4U4WA 4D2BA 4BY7D 5KNHI 4ZWCA 4O9HA 4IKYA 3HOWD 5A2NA 2ILKA 1GA3A 5D59A 2B8ZA 1QVNA 1I1RB 2B8XA 4NI9A 2IL6A 4NN7A 2V8NA 1LK3A 1RFBA 1F45B 4I77Z 2LMSA 4O6KA 1PV7A 1EERA 4TPHA 4CNIC 3NCBA 4A3MD 3EW3A 2L3YA 4W6VA 1Y6KL 5FUCA 1M49A 1KF9A 4XNJA 2L3OA 1JLIA 4BBRD 3DI2A 1HIJA 4A3BD 2B8YA 1HWHA 3UF5A 3N06A 2E9WC 3LB6B 1EMRA 1Y1WD 1ETEA 4QIQA 1M4AA 2Q98A 5A2OA 1IRLA 3QB1A 4NKQC 5L6YC 2B8UA 2OQPA 4IU8A 4U4TA 3PIWA 4YUEC 1BBNA 1HGUA 1V7NV 3I4ND 4BY1D 4BBSD 4DOHA 1HZIA 3O7PA 4IU9A 5LQBA 4YDYI 2INTA 1PVHB 3QAZA 3UEZE 4YPGC 4A3LD 4DKEA 5D6KA 4GC0A 1SCFA 3QWRB 2R7ZD 1RW5A 3IRHA 1M47A 4LDSA 5C4XD 5EQIA 2XUTA 5IYDD 1VLKA 3PIVA 4FA8E 5IP7D 4PYPA 3SE3B 3DLQI 4Z5RD 4OH3A 2ERJD 3QB7A 2Y5YA 1RCBA 3EJJA 4JA3A 4NN6A 1CD9A 4NEMA 4A3ID 2JA7D 1LQSL 1BGDA 4IKZA 4ZF7A 4NEJA 1EKUA 1M4RA 2C35A 4EXNA 1GNCA 1B5LA 1BP3A 1EVSA 3D48P 4UVMA 3HOXD 5D28B 3HHRA 2VUMD 4DKCA 2D48A 1A7MA 3O7QA 4D2CA 1IK0A 3DUHC 3MZGA 1IJZA 3HOYD 1Y6NL 3PO3D 1CN4C 1M48A 4A3ED 4GBYA 4IKXA
chains in the Genus database with same CATH topology
3N06A 2E9WC 5E4EA 3LB6B 4RS1A 1EMRA 4GS7A 5IYCD 1Y1WD 1ETEA 1HIKA 1HWGA 2Q7NB 4BXXD 2R93D 3B5KA 3WCYI 1IARA 2JA8D 3D85C 1EXZA 1AXIA 1M4AA 1Y14A 3OG6A 2Q98A 1IRLA 1AU1A 4A3GD 1AX8A 3QB1A 4A3DD 4GRWA 4NKQC 5FHXA 2JA6D 5L6YC 2B8UA 3L5XA 2OQPA 3SE4B 3BPLA 1YKBA 3NCCA 1PW6A 3H3VE 1J7VL 1Y6ML 3PIWA 3UX9A 3G9VB 1FG9A 4DKFA 1CNT1 1WU3I 2CYKA 4YUEC 1BBNA 1Z92A 2O26A 1M4BA 1HGUA 4A3KD 3BESL 1V7NV 1M4CA 2PSMA 4J4LC 1BUYA 1HULA 1PY2A 3I4ND 4BY1D 3I4MD 4BBSD 3NCEA 1D9GA 4DOHA 1CYLA 1HZIA 5LQBA 2GMFA 3H0GD 4A93D 4YDYI 2INTA 1A22A 3TGXB 1BGCA 5FLMD 1PVHB 3BPOA 5D71A 4ZS7A 1FYHA 1CSGA 2O27A 3OQ3A 3QAZA 3L5WI 1RHGA 4YPGC 3UEZE 4A3LD 5D22A 3HHCA 4X51A 4NI7A 4DKEA 5D70A 1ILKA 2Z3QA 3AYHA 1N1FA 3G6DA 4A3JD 2JA5D 5IYBD 1SCFA 3D87A 2B90A 3DGCL 3QWRB 2R7ZD 5D72A 4YQXA 2KZ1A 4A3FD 2B5IA 1RW5A 1IL6A 3IRHA 5TS9A 1ITIA 1M47A 1P9MB 3DI3A 4BY7D 5C4XD 5KNHI 5IYDD 2HYMB 1VLKA 3PIVA 4MHLA 3NPZA 4O9HA 5IP7D 4FA8E 2LAGA 1D9CA 3SE3B 5C7XA 2Z3RA 1LKIA 1Z7CA 3HOWD 3PO2D 1NBPA 3LB6A 3VA2A 3DLQI 3BPNA 4Z5RD 3S9DA 2ILKA 2ERJD 1INRA 3QB7A 1RCBA 3EJJA 4NN6A 1ITMA 2Q14A 5IP9D 1GA3A 3QT2C 1CD9A 2B8ZA 2XQBA 4NEMA 3HOZD 1QVNA 1I1RB 2B8XA 4NN5A 2IL6A 4NN7A 4NI9A 1BGEA 3N0PA 1HUWA 3UF2A 4A3ID 2JA7D 1LQSL 1BGDA 1LK3A 3HOVD 4WRLB 3HMXB 1RFBA 1F45B 4I77Z 2LMSA 4O6KA 3Q1SI 4ZF7A 1EERA 4NEJA 1ITLA 1EKUA 1M4RA 1ALUA 2C35A 4PS4A 4EXNA 4CNIC 3NCBA 4A3MD 1GNCA 4EXPA 1B5LA 3INKC 1BP3A 1EVSA 3D48P 3EW3A 2L3YA 5C44D 3HOXD 5D28B 1Y6KL 1V7MV 3HHRA 2B63D 5FUCA 4LRLA 1M49A 2B91A 2VUMD 1WCMD 1KF9A 4DKCA 2D48A 1A7MA 1PGRA 1Y1VD 4DKDA 4A3CD 5C3ED 3NCFA 1IK0A 2R92D 3DUHC 2O6IA 3MZGA 1IJZA 2D9QA 2L3OA 1JLIA 4BBRD 1F6FA 1HIJA 1Y6NL 3DI2A 3HOYD 3PO3D 3HOUD 1CN4C 1M48A 4A3ED 1BCNA 2H24A 4A3BD 1ITFA 2B8YA 1HWHA 3OG4A 3UF5A 3FKID
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I4N D;  5IYD D;  4BY1 D;  5IYC D;  3I4M D;  4BBS D;  1Y1W D;  2C35 A;  2R93 D;  4BXX D;  5IP7 D;  3H0G D;  4A93 D;  2JA8 D;  4A3M D;  3HOW D;  5FLM D;  3PO2 D;  1Y14 A;  5C44 D;  3HOX D;  4A3G D;  2B63 D;  2VUM D;  4A3D D;  4A3L D;  1WCM D;  2JA6 D;  1Y1V D;  4A3C D;  5C3E D;  3AYH A;  2JA5 D;  4A3J D;  3H3V E;  2R92 D;  5IYB D;  5IP9 D;  2R7Z D;  3HOZ D;  3HOY D;  4A3F D;  4BBR D;  3PO3 D;  4A3I D;  2JA7 D;  4A3E D;  3HOU D;  4A3B D;  4A3K D;  3HOV D;  4BY7 D;  5C4X D;  3FKI D; 
#chains in the Genus database with same CATH topology
 5E4E A;  4GS7 A;  1HWG A;  1IAR A;  3D85 C;  1AXI A;  3OG6 A;  4JRE A;  4A3G D;  2JA6 D;  3NCC A;  3H3V E;  1J7V L;  4TPG A;  4DKF A;  2PSM A;  4J4L C;  1BUY A;  1CYL A;  4Q65 A;  1A22 A;  3TGX B;  3OQ3 A;  1RHG A;  5D22 A;  3AYH A;  1N1F A;  4A3J D;  2B90 A;  2B5I A;  1ITI A;  3DI3 A;  4MHL A;  2LAG A;  1D9C A;  1PW4 A;  4TPJ A;  2Z3R A;  1Z7C A;  5C65 A;  1NBP A;  4APS A;  2CFP A;  3LB6 A;  3VA2 A;  4ZW9 A;  3S9D A;  5IP9 D;  1ITM A;  2Q14 A;  2XQB A;  1BGE A;  3UF2 A;  1ITL A;  2CFQ A;  4OAA A;  4EXP A;  1V7M V;  2B63 D;  2B91 A;  4A3C D;  4DKD A;  2R92 D;  1F6F A;  1BCN A;  2H24 A;  3OG4 A;  3FKI D;  4BXX D;  3B5K A;  3WCY I;  1AU1 A;  1AX8 A;  4U4V A;  4A3D D;  3WDO A;  3SE4 B;  1YKB A;  1PW6 A;  3UX9 A;  1FG9 A;  5D58 A;  1WU3 I;  1M4B A;  4YBQ A;  4JR9 A;  3BES L;  1PY2 A;  3I4M D;  3H0G D;  4IKW A;  5EQH A;  1BGC A;  4J05 A;  4ZS7 A;  4ZYR A;  1CSG A;  3L5W I;  4X51 A;  4NI7 A;  1ILK A;  2JA5 D;  5IYB D;  3DGC L;  5D72 A;  4YQX A;  4A3F D;  4D2D A;  1P9M B;  4GBZ A;  4LEP A;  2HYM B;  3NPZ A;  5C7X A;  1LKI A;  3PO2 D;  3BPN A;  1INR A;  4IKV A;  3QT2 C;  3HOZ D;  4NN5 A;  5GXB A;  3N0P A;  1HUW A;  3HOV D;  4WRL B;  3HMX B;  3Q1S I;  1ALU A;  4PS4 A;  3INK C;  5C44 D;  4LRL A;  1WCM D;  1PGR A;  1Y1V D;  5C3E D;  3NCF A;  4XNI A;  2O6I A;  2D9Q A;  3HOU D;  1ITF A;  4RS1 A;  5IYC D;  1HIK A;  2Q7N B;  2R93 D;  2JA8 D;  1EXZ A;  1Y14 A;  4ZWB A;  4GRW A;  5FHX A;  4YB9 D;  3L5X A;  3BPL A;  1Y6M L;  3G9V B;  1CNT 1;  2CYK A;  1Z92 A;  2O26 A;  4A3K D;  1M4C A;  1HUL A;  3NCE A;  1D9G A;  2GMF A;  4A93 D;  5EQG A;  5FLM D;  3BPO A;  5D71 A;  1FYH A;  2O27 A;  3HHC A;  5D70 A;  2Z3Q A;  3G6D A;  3D87 A;  1PV6 A;  2KZ1 A;  1IL6 A;  5TS9 A;  4U4W A;  4D2B A;  4BY7 D;  5KNH I;  4ZWC A;  4O9H A;  4IKY A;  3HOW D;  5A2N A;  2ILK A;  1GA3 A;  5D59 A;  2B8Z A;  1QVN A;  1I1R B;  2B8X A;  4NI9 A;  2IL6 A;  4NN7 A;  2V8N A;  1LK3 A;  1RFB A;  1F45 B;  4I77 Z;  2LMS A;  4O6K A;  1PV7 A;  1EER A;  4TPH A;  4CNI C;  3NCB A;  4A3M D;  3EW3 A;  2L3Y A;  4W6V A;  1Y6K L;  5FUC A;  1M49 A;  1KF9 A;  4XNJ A;  2L3O A;  1JLI A;  4BBR D;  3DI2 A;  1HIJ A;  4A3B D;  2B8Y A;  1HWH A;  3UF5 A;  3N06 A;  2E9W C;  3LB6 B;  1EMR A;  1Y1W D;  1ETE A;  4QIQ A;  1M4A A;  2Q98 A;  5A2O A;  1IRL A;  3QB1 A;  4NKQ C;  5L6Y C;  2B8U A;  2OQP A;  4IU8 A;  4U4T A;  3PIW A;  4YUE C;  1BBN A;  1HGU A;  1V7N V;  3I4N D;  4BY1 D;  4BBS D;  4DOH A;  1HZI A;  3O7P A;  4IU9 A;  5LQB A;  4YDY I;  2INT A;  1PVH B;  3QAZ A;  3UEZ E;  4YPG C;  4A3L D;  4DKE A;  5D6K A;  4GC0 A;  1SCF A;  3QWR B;  2R7Z D;  1RW5 A;  3IRH A;  1M47 A;  4LDS A;  5C4X D;  5EQI A;  2XUT A;  5IYD D;  1VLK A;  3PIV A;  4FA8 E;  5IP7 D;  4PYP A;  3SE3 B;  3DLQ I;  4Z5R D;  4OH3 A;  2ERJ D;  3QB7 A;  2Y5Y A;  1RCB A;  3EJJ A;  4JA3 A;  4NN6 A;  1CD9 A;  4NEM A;  4A3I D;  2JA7 D;  1LQS L;  1BGD A;  4IKZ A;  4ZF7 A;  4NEJ A;  1EKU A;  1M4R A;  2C35 A;  4EXN A;  1GNC A;  1B5L A;  1BP3 A;  1EVS A;  3D48 P;  4UVM A;  3HOX D;  5D28 B;  3HHR A;  2VUM D;  4DKC A;  2D48 A;  1A7M A;  3O7Q A;  4D2C A;  1IK0 A;  3DUH C;  3MZG A;  1IJZ A;  3HOY D;  1Y6N L;  3PO3 D;  1CN4 C;  1M48 A;  4A3E D;  4GBY A;  4IKX A; 
#chains in the Genus database with same CATH homology
 3N06 A;  2E9W C;  5E4E A;  3LB6 B;  4RS1 A;  1EMR A;  4GS7 A;  5IYC D;  1Y1W D;  1ETE A;  1HIK A;  1HWG A;  2Q7N B;  4BXX D;  2R93 D;  3B5K A;  3WCY I;  1IAR A;  2JA8 D;  3D85 C;  1EXZ A;  1AXI A;  1M4A A;  1Y14 A;  3OG6 A;  2Q98 A;  1IRL A;  1AU1 A;  4A3G D;  1AX8 A;  3QB1 A;  4A3D D;  4GRW A;  4NKQ C;  5FHX A;  2JA6 D;  5L6Y C;  2B8U A;  3L5X A;  2OQP A;  3SE4 B;  3BPL A;  1YKB A;  3NCC A;  1PW6 A;  3H3V E;  1J7V L;  1Y6M L;  3PIW A;  3UX9 A;  3G9V B;  1FG9 A;  4DKF A;  1CNT 1;  1WU3 I;  2CYK A;  4YUE C;  1BBN A;  1Z92 A;  2O26 A;  1M4B A;  1HGU A;  4A3K D;  3BES L;  1V7N V;  1M4C A;  2PSM A;  4J4L C;  1BUY A;  1HUL A;  1PY2 A;  3I4N D;  4BY1 D;  3I4M D;  4BBS D;  3NCE A;  1D9G A;  4DOH A;  1CYL A;  1HZI A;  5LQB A;  2GMF A;  3H0G D;  4A93 D;  4YDY I;  2INT A;  1A22 A;  3TGX B;  1BGC A;  5FLM D;  1PVH B;  3BPO A;  5D71 A;  4ZS7 A;  1FYH A;  1CSG A;  2O27 A;  3OQ3 A;  3QAZ A;  3L5W I;  1RHG A;  4YPG C;  3UEZ E;  4A3L D;  5D22 A;  3HHC A;  4X51 A;  4NI7 A;  4DKE A;  5D70 A;  1ILK A;  2Z3Q A;  3AYH A;  1N1F A;  3G6D A;  4A3J D;  2JA5 D;  5IYB D;  1SCF A;  3D87 A;  2B90 A;  3DGC L;  3QWR B;  2R7Z D;  5D72 A;  4YQX A;  2KZ1 A;  4A3F D;  2B5I A;  1RW5 A;  1IL6 A;  3IRH A;  5TS9 A;  1ITI A;  1M47 A;  1P9M B;  3DI3 A;  4BY7 D;  5C4X D;  5KNH I;  5IYD D;  2HYM B;  1VLK A;  3PIV A;  4MHL A;  3NPZ A;  4O9H A;  5IP7 D;  4FA8 E;  2LAG A;  1D9C A;  3SE3 B;  5C7X A;  2Z3R A;  1LKI A;  1Z7C A;  3HOW D;  3PO2 D;  1NBP A;  3LB6 A;  3VA2 A;  3DLQ I;  3BPN A;  4Z5R D;  3S9D A;  2ILK A;  2ERJ D;  1INR A;  3QB7 A;  1RCB A;  3EJJ A;  4NN6 A;  1ITM A;  2Q14 A;  5IP9 D;  1GA3 A;  3QT2 C;  1CD9 A;  2B8Z A;  2XQB A;  4NEM A;  3HOZ D;  1QVN A;  1I1R B;  2B8X A;  4NN5 A;  2IL6 A;  4NN7 A;  4NI9 A;  1BGE A;  3N0P A;  1HUW A;  3UF2 A;  4A3I D;  2JA7 D;  1LQS L;  1BGD A;  1LK3 A;  3HOV D;  4WRL B;  3HMX B;  1RFB A;  1F45 B;  4I77 Z;  2LMS A;  4O6K A;  3Q1S I;  4ZF7 A;  1EER A;  4NEJ A;  1ITL A;  1EKU A;  1M4R A;  1ALU A;  2C35 A;  4PS4 A;  4EXN A;  4CNI C;  3NCB A;  4A3M D;  1GNC A;  4EXP A;  1B5L A;  3INK C;  1BP3 A;  1EVS A;  3D48 P;  3EW3 A;  2L3Y A;  5C44 D;  3HOX D;  5D28 B;  1Y6K L;  1V7M V;  3HHR A;  2B63 D;  5FUC A;  4LRL A;  1M49 A;  2B91 A;  2VUM D;  1WCM D;  1KF9 A;  4DKC A;  2D48 A;  1A7M A;  1PGR A;  1Y1V D;  4DKD A;  4A3C D;  5C3E D;  3NCF A;  1IK0 A;  2R92 D;  3DUH C;  2O6I A;  3MZG A;  1IJZ A;  2D9Q A;  2L3O A;  1JLI A;  4BBR D;  1F6F A;  1HIJ A;  1Y6N L;  3DI2 A;  3HOY D;  3PO3 D;  3HOU D;  1CN4 C;  1M48 A;  4A3E D;  1BCN A;  2H24 A;  4A3B D;  1ITF A;  2B8Y A;  1HWH A;  3OG4 A;  3UF5 A;  3FKI D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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