4A3ED

Rna polymerase ii initial transcribing complex with a 5nt dna-rna hybrid and soaked with ampcpp
Total Genus 53
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
219
structure length
178
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 53
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4a3eD02
3FKID 3PO2D 3HOVD 1Y14A 3HOXD 3H3VE 2JA6D 5IYDD 4A3LD 4A93D 3I4ND 1Y1VD 5IP9D 2JA7D 3H0GD 2JA5D 2R92D 5C44D 4A3JD 5C3ED 3AYHA 2VUMD 4BXXD 1WCMD 5FLMD 4BBSD 4BBRD 4A3ED 3HOUD 3HOZD 2R93D 5C4XD 4BY1D 5IYCD 3HOYD 4A3BD 3I4MD 4A3FD 4A3KD 3PO3D 4A3CD 4A3ID 1Y1WD 4A3DD 2R7ZD 3HOWD 2JA8D 4A3GD 4BY7D 5IP7D 4A3MD 2B63D 5IYBD 2C35A
chains in the Genus database with same CATH superfamily
4JR9A 1IK0A 5LQBA 1BGEA 3DGCL 1M49A 3N0PA 3HOUD 4DOHA 4U4TA 3OG6A 1LKIA 1Z92A 4JREA 1EXZA 3DUHC 2LAGA 4ZS7A 4PS4A 3HHCA 2L3YA 4GBYA 4IKWA 4A3LD 2E9WC 1EVSA 1Z7CA 2JA7D 1BUYA 1PW4A 3S9DA 4Z5RD 2Q98A 4YBQA 1WCMD 4ZW9A 4DKFA 4XNIA 2R93D 2Z3QA 1ITIA 5C7XA 1GNCA 4I77Z 2B91A 4GC0A 1Y6NL 1N1FA 4QIQA 1RCBA 1RHGA 3D48P 5C65A 3N06A 3WDOA 3BPOA 2O6IA 4BXXD 3PIWA 4BBSD 3SE4B 4W6VA 1P9MB 1CN4C 1ITFA 1AX8A 1LQSL 1PV7A 3UF2A 5IYBD 1ITMA 1D9GA 3NPZA 3PIVA 5C3ED 2PSMA 2LMSA 1PY2A 3DI2A 3G9VB 3NCBA 3HOYD 4O9HA 2O27A 4A3ID 3OQ3A 4TPJA 3NCCA 4LRLA 3QB7A 3HHRA 3IRHA 4YPGC 1CNT1 5FUCA 1PW6A 4A3JD 1HULA 1IJZA 3BPLA 2IL6A 2L3OA 5D59A 4BBRD 3HOZD 5GXBA 3EW3A 4EXPA 1CYLA 3BESL 4NI7A 3PO3D 4A3KD 4NEJA 1EKUA 3DI3A 2R7ZD 2JA8D 3QT2C 4WRLB 1WU3I 2JA6D 1AXIA 4LEPA 4D2DA 1GA3A 1F6FA 3L5WI 3LB6B 4IU9A 1HIJA 2OQPA 4DKDA 5D28B 4TPGA 2O26A 3HOXD 1EMRA 2D9QA 3BPNA 1INRA 1HWGA 4IU8A 3HMXB 3INKC 2V8NA 3UEZE 3HOWD 4A3GD 4FA8E 2Y5YA 5TS9A 3PO2D 3HOVD 2ERJD 5IP9D 2R92D 1VLKA 2Q7NB 1V7NV 4A3ED 4OAAA 4J4LC 1ALUA 4A3BD 4A3CD 4A3DD 4YQXA 1M4CA 4O6KA 1Y6ML 5D72A 2H24A 4PYPA 4X51A 5IP7D 1A7MA 3FKID 4IKYA 1HWHA 1A22A 1NBPA 4A93D 4GRWA 3I4ND 1AU1A 2B8ZA 3H0GD 4NKQC 3O7PA 3QAZA 1M4AA 1HZIA 1HIKA 1PGRA 4NN7A 1M47A 2KZ1A 3VA2A 4IKXA 4ZYRA 5IYDD 1Y6KL 1Y1VD 4U4VA 1M48A 4JA3A 4OH3A 5FLMD 5C4XD 4D2BA 1J7VL 2XUTA 3L5XA 3QWRB 1RW5A 2HYMB 4ZWCA 2C35A 1Y14A 5D22A 1FYHA 5EQIA 5C44D 5A2NA 4TPHA 1HUWA 5D70A 3NCEA 4GS7A 5FHXA 1M4RA 1BGDA 3WCYI 4D2CA 2B63D 5EQHA 3D87A 4DKEA 3DLQI 3D85C 2CYKA 1V7MV 4J05A 1LK3A 2INTA 2Q14A 4NEMA 4UVMA 4MHLA 1ITLA 1D9CA 4XNJA 4ZF7A 1M4BA 3NCFA 4YDYI 1F45B 4EXNA 3O7QA 1QVNA 3MZGA 1BCNA 2CFQA 2B90A 2JA5D 1JLIA 3LB6A 4IKVA 4U4WA 1SCFA 1CSGA 4YUEC 5IYCD 2B8UA 2ILKA 2B8YA 1EERA 1Y1WD 1BBNA 3TGXB 3B5KA 1I1RB 1ILKA 3AYHA 2XQBA 3QB1A 4NI9A 3UF5A 4GBZA 4A3FD 4IKZA 4BY7D 4A3MD 4APSA 3EJJA 1CD9A 2Z3RA 5L6YC 5A2OA 4YB9D 4Q65A 2VUMD 4CNIC 1PV6A 1ETEA 3Q1SI 4LDSA 5D58A 3I4MD 3UX9A 4ZWBA 1BGCA 1IARA 5E4EA 1YKBA 5D71A 3G6DA 5EQGA 2D48A 1IRLA 3H3VE 1B5LA 3SE3B 1RFBA 5D6KA 2B8XA 2B5IA 2CFPA 1BP3A 1PVHB 4NN6A 4DKCA 4BY1D 4RS1A 5KNHI 4NN5A 1HGUA 1KF9A 2GMFA 1IL6A 1FG9A 3OG4A
chains in the Genus database with same CATH topology
3FKID 1HWHA 1A22A 3HHRA 3QB7A 1NBPA 3IRHA 3NCFA 4YDYI 1F45B 1CNT1 4YPGC 4EXNA 5FUCA 4A93D 4GRWA 3I4ND 1AU1A 1QVNA 3MZGA 5LQBA 1PW6A 2B8ZA 1IK0A 3H0GD 1BCNA 2B90A 1BGEA 2JA5D 1JLIA 3DGCL 1M49A 4A3JD 3LB6A 1HULA 1IJZA 4NKQC 3BPLA 3N0PA 2IL6A 2L3OA 4BBRD 3QAZA 3HOUD 3HOZD 4DOHA 3EW3A 1SCFA 1CSGA 4YUEC 1M4AA 4EXPA 5IYCD 3BESL 4NI7A 2B8UA 1CYLA 1HZIA 2B8YA 2ILKA 3OG6A 4A3KD 3PO3D 1HIKA 4NEJA 1EKUA 1EERA 1Y1WD 1LKIA 1Z92A 3DI3A 2R7ZD 1BBNA 2JA8D 1PGRA 3TGXB 1EXZA 3DUHC 2LAGA 3QT2C 4NN7A 4ZS7A 1M47A 2KZ1A 4WRLB 4PS4A 3VA2A 3B5KA 1I1RB 3HHCA 1WU3I 2L3YA 2JA6D 1AXIA 5IYDD 1Y6KL 4A3LD 1ILKA 2E9WC 1Y1VD 1EVSA 1Z7CA 2JA7D 1BUYA 1M48A 3S9DA 4Z5RD 3AYHA 2XQBA 2Q98A 3QB1A 1WCMD 5FLMD 1GA3A 4DKFA 2R93D 2Z3QA 5C4XD 5C7XA 4NI9A 4I77Z 1ITIA 1GNCA 1J7VL 1F6FA 2B91A 3UF5A 3L5WI 3LB6B 4A3FD 3L5XA 3QWRB 1HIJA 2OQPA 1RW5A 4DKDA 1Y6NL 2HYMB 1N1FA 4BY7D 5D28B 4A3MD 1RCBA 2O26A 2C35A 3EJJA 1Y14A 1EMRA 1RHGA 2D9QA 3BPNA 1FYHA 5D22A 3HOXD 1CD9A 1INRA 2Z3RA 5L6YC 1HWGA 3D48P 3NCCA 5C44D 3N06A 3BPOA 2VUMD 2O6IA 4BXXD 3HMXB 3PIWA 3INKC 4BBSD 4CNIC 1ETEA 1HUWA 3SE4B 3Q1SI 5D70A 3NCEA 1P9MB 4GS7A 5FHXA 1M4RA 3I4MD 3UEZE 1BGDA 1CN4C 3UX9A 1BGCA 1IARA 1ITFA 5E4EA 3WCYI 1AX8A 3HOWD 4A3GD 1LQSL 1YKBA 5D71A 4FA8E 2B63D 3UF2A 5IYBD 3G6DA 5TS9A 3PO2D 2D48A 3HOVD 1ITMA 1IRLA 1D9GA 3H3VE 2ERJD 3D87A 3NPZA 5IP9D 3PIVA 1B5LA 4DKEA 3SE3B 3DLQI 1RFBA 2R92D 3D85C 2B8XA 2B5IA 4LRLA 5C3ED 2PSMA 2CYKA 1V7MV 1VLKA 2LMSA 1PY2A 3DI2A 3G9VB 2Q7NB 1V7NV 4A3ED 1BP3A 1LK3A 2INTA 1PVHB 2Q14A 4NN6A 4DKCA 4BY1D 4J4LC 3NCBA 1ALUA 4NEMA 4RS1A 3HOYD 4A3BD 4A3CD 4MHLA 4O9HA 5KNHI 2O27A 4A3ID 4A3DD 4NN5A 1ITLA 1M4CA 4O6KA 1HGUA 4YQXA 1Y6ML 1KF9A 5D72A 1D9CA 2H24A 3OQ3A 4X51A 5IP7D 4ZF7A 2GMFA 1IL6A 1A7MA 1FG9A 3OG4A 1M4BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FKI D;  3PO2 D;  3HOV D;  1Y14 A;  3HOX D;  3H3V E;  2JA6 D;  5IYD D;  4A3L D;  4A93 D;  3I4N D;  1Y1V D;  5IP9 D;  2JA7 D;  3H0G D;  2JA5 D;  2R92 D;  5C44 D;  4A3J D;  5C3E D;  3AYH A;  2VUM D;  4BXX D;  1WCM D;  5FLM D;  4BBS D;  4BBR D;  4A3E D;  3HOU D;  3HOZ D;  2R93 D;  5C4X D;  4BY1 D;  5IYC D;  3HOY D;  4A3B D;  3I4M D;  4A3F D;  4A3K D;  3PO3 D;  4A3C D;  4A3I D;  1Y1W D;  4A3D D;  2R7Z D;  3HOW D;  2JA8 D;  4A3G D;  4BY7 D;  5IP7 D;  4A3M D;  2B63 D;  5IYB D;  2C35 A; 
#chains in the Genus database with same CATH topology
 4JR9 A;  1IK0 A;  5LQB A;  1BGE A;  3DGC L;  1M49 A;  3N0P A;  3HOU D;  4DOH A;  4U4T A;  3OG6 A;  1LKI A;  1Z92 A;  4JRE A;  1EXZ A;  3DUH C;  2LAG A;  4ZS7 A;  4PS4 A;  3HHC A;  2L3Y A;  4GBY A;  4IKW A;  4A3L D;  2E9W C;  1EVS A;  1Z7C A;  2JA7 D;  1BUY A;  1PW4 A;  3S9D A;  4Z5R D;  2Q98 A;  4YBQ A;  1WCM D;  4ZW9 A;  4DKF A;  4XNI A;  2R93 D;  2Z3Q A;  1ITI A;  5C7X A;  1GNC A;  4I77 Z;  2B91 A;  4GC0 A;  1Y6N L;  1N1F A;  4QIQ A;  1RCB A;  1RHG A;  3D48 P;  5C65 A;  3N06 A;  3WDO A;  3BPO A;  2O6I A;  4BXX D;  3PIW A;  4BBS D;  3SE4 B;  4W6V A;  1P9M B;  1CN4 C;  1ITF A;  1AX8 A;  1LQS L;  1PV7 A;  3UF2 A;  5IYB D;  1ITM A;  1D9G A;  3NPZ A;  3PIV A;  5C3E D;  2PSM A;  2LMS A;  1PY2 A;  3DI2 A;  3G9V B;  3NCB A;  3HOY D;  4O9H A;  2O27 A;  4A3I D;  3OQ3 A;  4TPJ A;  3NCC A;  4LRL A;  3QB7 A;  3HHR A;  3IRH A;  4YPG C;  1CNT 1;  5FUC A;  1PW6 A;  4A3J D;  1HUL A;  1IJZ A;  3BPL A;  2IL6 A;  2L3O A;  5D59 A;  4BBR D;  3HOZ D;  5GXB A;  3EW3 A;  4EXP A;  1CYL A;  3BES L;  4NI7 A;  3PO3 D;  4A3K D;  4NEJ A;  1EKU A;  3DI3 A;  2R7Z D;  2JA8 D;  3QT2 C;  4WRL B;  1WU3 I;  2JA6 D;  1AXI A;  4LEP A;  4D2D A;  1GA3 A;  1F6F A;  3L5W I;  3LB6 B;  4IU9 A;  1HIJ A;  2OQP A;  4DKD A;  5D28 B;  4TPG A;  2O26 A;  3HOX D;  1EMR A;  2D9Q A;  3BPN A;  1INR A;  1HWG A;  4IU8 A;  3HMX B;  3INK C;  2V8N A;  3UEZ E;  3HOW D;  4A3G D;  4FA8 E;  2Y5Y A;  5TS9 A;  3PO2 D;  3HOV D;  2ERJ D;  5IP9 D;  2R92 D;  1VLK A;  2Q7N B;  1V7N V;  4A3E D;  4OAA A;  4J4L C;  1ALU A;  4A3B D;  4A3C D;  4A3D D;  4YQX A;  1M4C A;  4O6K A;  1Y6M L;  5D72 A;  2H24 A;  4PYP A;  4X51 A;  5IP7 D;  1A7M A;  3FKI D;  4IKY A;  1HWH A;  1A22 A;  1NBP A;  4A93 D;  4GRW A;  3I4N D;  1AU1 A;  2B8Z A;  3H0G D;  4NKQ C;  3O7P A;  3QAZ A;  1M4A A;  1HZI A;  1HIK A;  1PGR A;  4NN7 A;  1M47 A;  2KZ1 A;  3VA2 A;  4IKX A;  4ZYR A;  5IYD D;  1Y6K L;  1Y1V D;  4U4V A;  1M48 A;  4JA3 A;  4OH3 A;  5FLM D;  5C4X D;  4D2B A;  1J7V L;  2XUT A;  3L5X A;  3QWR B;  1RW5 A;  2HYM B;  4ZWC A;  2C35 A;  1Y14 A;  5D22 A;  1FYH A;  5EQI A;  5C44 D;  5A2N A;  4TPH A;  1HUW A;  5D70 A;  3NCE A;  4GS7 A;  5FHX A;  1M4R A;  1BGD A;  3WCY I;  4D2C A;  2B63 D;  5EQH A;  3D87 A;  4DKE A;  3DLQ I;  3D85 C;  2CYK A;  1V7M V;  4J05 A;  1LK3 A;  2INT A;  2Q14 A;  4NEM A;  4UVM A;  4MHL A;  1ITL A;  1D9C A;  4XNJ A;  4ZF7 A;  1M4B A;  3NCF A;  4YDY I;  1F45 B;  4EXN A;  3O7Q A;  1QVN A;  3MZG A;  1BCN A;  2CFQ A;  2B90 A;  2JA5 D;  1JLI A;  3LB6 A;  4IKV A;  4U4W A;  1SCF A;  1CSG A;  4YUE C;  5IYC D;  2B8U A;  2ILK A;  2B8Y A;  1EER A;  1Y1W D;  1BBN A;  3TGX B;  3B5K A;  1I1R B;  1ILK A;  3AYH A;  2XQB A;  3QB1 A;  4NI9 A;  3UF5 A;  4GBZ A;  4A3F D;  4IKZ A;  4BY7 D;  4A3M D;  4APS A;  3EJJ A;  1CD9 A;  2Z3R A;  5L6Y C;  5A2O A;  4YB9 D;  4Q65 A;  2VUM D;  4CNI C;  1PV6 A;  1ETE A;  3Q1S I;  4LDS A;  5D58 A;  3I4M D;  3UX9 A;  4ZWB A;  1BGC A;  1IAR A;  5E4E A;  1YKB A;  5D71 A;  3G6D A;  5EQG A;  2D48 A;  1IRL A;  3H3V E;  1B5L A;  3SE3 B;  1RFB A;  5D6K A;  2B8X A;  2B5I A;  2CFP A;  1BP3 A;  1PVH B;  4NN6 A;  4DKC A;  4BY1 D;  4RS1 A;  5KNH I;  4NN5 A;  1HGU A;  1KF9 A;  2GMF A;  1IL6 A;  1FG9 A;  3OG4 A; 
#chains in the Genus database with same CATH homology
 3FKI D;  1HWH A;  1A22 A;  3HHR A;  3QB7 A;  1NBP A;  3IRH A;  3NCF A;  4YDY I;  1F45 B;  1CNT 1;  4YPG C;  4EXN A;  5FUC A;  4A93 D;  4GRW A;  3I4N D;  1AU1 A;  1QVN A;  3MZG A;  5LQB A;  1PW6 A;  2B8Z A;  1IK0 A;  3H0G D;  1BCN A;  2B90 A;  1BGE A;  2JA5 D;  1JLI A;  3DGC L;  1M49 A;  4A3J D;  3LB6 A;  1HUL A;  1IJZ A;  4NKQ C;  3BPL A;  3N0P A;  2IL6 A;  2L3O A;  4BBR D;  3QAZ A;  3HOU D;  3HOZ D;  4DOH A;  3EW3 A;  1SCF A;  1CSG A;  4YUE C;  1M4A A;  4EXP A;  5IYC D;  3BES L;  4NI7 A;  2B8U A;  1CYL A;  1HZI A;  2B8Y A;  2ILK A;  3OG6 A;  4A3K D;  3PO3 D;  1HIK A;  4NEJ A;  1EKU A;  1EER A;  1Y1W D;  1LKI A;  1Z92 A;  3DI3 A;  2R7Z D;  1BBN A;  2JA8 D;  1PGR A;  3TGX B;  1EXZ A;  3DUH C;  2LAG A;  3QT2 C;  4NN7 A;  4ZS7 A;  1M47 A;  2KZ1 A;  4WRL B;  4PS4 A;  3VA2 A;  3B5K A;  1I1R B;  3HHC A;  1WU3 I;  2L3Y A;  2JA6 D;  1AXI A;  5IYD D;  1Y6K L;  4A3L D;  1ILK A;  2E9W C;  1Y1V D;  1EVS A;  1Z7C A;  2JA7 D;  1BUY A;  1M48 A;  3S9D A;  4Z5R D;  3AYH A;  2XQB A;  2Q98 A;  3QB1 A;  1WCM D;  5FLM D;  1GA3 A;  4DKF A;  2R93 D;  2Z3Q A;  5C4X D;  5C7X A;  4NI9 A;  4I77 Z;  1ITI A;  1GNC A;  1J7V L;  1F6F A;  2B91 A;  3UF5 A;  3L5W I;  3LB6 B;  4A3F D;  3L5X A;  3QWR B;  1HIJ A;  2OQP A;  1RW5 A;  4DKD A;  1Y6N L;  2HYM B;  1N1F A;  4BY7 D;  5D28 B;  4A3M D;  1RCB A;  2O26 A;  2C35 A;  3EJJ A;  1Y14 A;  1EMR A;  1RHG A;  2D9Q A;  3BPN A;  1FYH A;  5D22 A;  3HOX D;  1CD9 A;  1INR A;  2Z3R A;  5L6Y C;  1HWG A;  3D48 P;  3NCC A;  5C44 D;  3N06 A;  3BPO A;  2VUM D;  2O6I A;  4BXX D;  3HMX B;  3PIW A;  3INK C;  4BBS D;  4CNI C;  1ETE A;  1HUW A;  3SE4 B;  3Q1S I;  5D70 A;  3NCE A;  1P9M B;  4GS7 A;  5FHX A;  1M4R A;  3I4M D;  3UEZ E;  1BGD A;  1CN4 C;  3UX9 A;  1BGC A;  1IAR A;  1ITF A;  5E4E A;  3WCY I;  1AX8 A;  3HOW D;  4A3G D;  1LQS L;  1YKB A;  5D71 A;  4FA8 E;  2B63 D;  3UF2 A;  5IYB D;  3G6D A;  5TS9 A;  3PO2 D;  2D48 A;  3HOV D;  1ITM A;  1IRL A;  1D9G A;  3H3V E;  2ERJ D;  3D87 A;  3NPZ A;  5IP9 D;  3PIV A;  1B5L A;  4DKE A;  3SE3 B;  3DLQ I;  1RFB A;  2R92 D;  3D85 C;  2B8X A;  2B5I A;  4LRL A;  5C3E D;  2PSM A;  2CYK A;  1V7M V;  1VLK A;  2LMS A;  1PY2 A;  3DI2 A;  3G9V B;  2Q7N B;  1V7N V;  4A3E D;  1BP3 A;  1LK3 A;  2INT A;  1PVH B;  2Q14 A;  4NN6 A;  4DKC A;  4BY1 D;  4J4L C;  3NCB A;  1ALU A;  4NEM A;  4RS1 A;  3HOY D;  4A3B D;  4A3C D;  4MHL A;  4O9H A;  5KNH I;  2O27 A;  4A3I D;  4A3D D;  4NN5 A;  1ITL A;  1M4C A;  4O6K A;  1HGU A;  4YQX A;  1Y6M L;  1KF9 A;  5D72 A;  1D9C A;  2H24 A;  3OQ3 A;  4X51 A;  5IP7 D;  4ZF7 A;  2GMF A;  1IL6 A;  1A7M A;  1FG9 A;  3OG4 A;  1M4B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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