4A3LD

Rna polymerase ii initial transcribing complex with a 7nt dna-rna hybrid and soaked with ampcpp
Total Genus 52
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
219
structure length
178
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of initial RNA polymerase II transcription.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
total genus 52
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2011-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4a3lD02
4A3MD 3HOXD 3AYHA 4A3ID 4A3ED 4A3FD 3PO3D 4A3JD 2JA5D 3H3VE 3PO2D 3HOYD 3HOWD 4A3BD 4A3LD 2C35A 4BBSD 2R93D 2JA6D 3H0GD 3HOUD 3HOZD 2R7ZD 2VUMD 2B63D 2R92D 4BBRD 1Y1WD 4A93D 3I4MD 2JA8D 1Y1VD 4BXXD 5IYCD 1WCMD 5IP9D 5IP7D 4A3CD 3HOVD 1Y14A 5C44D 3I4ND 4BY1D 4A3KD 5IYDD 5IYBD 4A3DD 2JA7D 4BY7D 5C3ED 5FLMD 3FKID 5C4XD 4A3GD
chains in the Genus database with same CATH superfamily
3DLQI 3OG4A 1M4BA 1EMRA 1ITMA 4D2DA 1CNT1 1V7NV 1PVHB 4GRWA 5D72A 4GBZA 1AU1A 1B5LA 4J4LC 1CN4C 5D71A 4I77Z 2L3OA 3NCFA 1ETEA 4BY1D 3LB6B 4IKWA 4A3DD 1RW5A 4DKCA 3UEZE 3AYHA 4A3FD 3Q1SI 3H3VE 1SCFA 4YQXA 2O27A 4W6VA 1HIKA 2Y5YA 1PW4A 1A22A 2KZ1A 3UF5A 5IP7D 4A3CD 1Z7CA 1LQSL 3N0PA 2L3YA 3FKID 4A3GD 3BPOA 1ITFA 5D70A 4A3JD 4JREA 1Y6ML 2B5IA 1EKUA 1HWHA 4GC0A 1M4RA 3QB7A 3DGCL 5L6YC 4IKYA 1A7MA 5IYBD 4JA3A 5TS9A 5GXBA 2V8NA 3SE4B 4YDYI 4BBSD 1HZIA 1D9CA 1F6FA 3EW3A 1ITLA 4LRLA 3UX9A 2B8XA 4IKXA 1LK3A 4DKFA 4NN7A 1IL6A 3WDOA 4DOHA 3TGXB 1BBNA 1VLKA 4DKEA 1ITIA 2Q7NB 2Q14A 3QWRB 4ZYRA 4ZWBA 1CYLA 1GA3A 3S9DA 3D85C 4LDSA 4TPHA 2O6IA 4A3ID 3PO3D 4O9HA 2B8YA 4GS7A 2PSMA 2C35A 3BPLA 1M4CA 1V7MV 4TPJA 3L5WI 1IJZA 2Z3QA 4O6KA 2B90A 5FHXA 2B8ZA 4ZWCA 4BY7D 2LAGA 4U4TA 4X51A 3D48P 3O7PA 4PS4A 1PGRA 3EJJA 3HOYD 4A3LD 5D6KA 1AX8A 1RHGA 2B91A 1RFBA 4YPGC 4OH3A 1BGEA 1HWGA 3HOVD 1IRLA 5D58A 1I1RB 4NN5A 3PIWA 2E9WC 1EXZA 1KF9A 4D2CA 2B8UA 2OQPA 5EQIA 1BGCA 3HOZD 4IKZA 2CFQA 5E4EA 1AXIA 5A2NA 5C44D 3G6DA 2ILKA 5D59A 3NCCA 3SE3B 3HMXB 4UVMA 4XNJA 2HYMB 2GMFA 1YKBA 2JA6D 4PYPA 2R7ZD 3VA2A 2B63D 3QB1A 4FA8E 2JA8D 2XUTA 5IP9D 3DI2A 3I4ND 3G9VB 5C7XA 1IARA 1FYHA 1PY2A 1IK0A 3OG6A 1BCNA 2CFPA 3INKC 4MHLA 2R93D 4ZW9A 4OAAA 3QT2C 3BESL 5D22A 1Y1VD 1ALUA 5IYCD 1EVSA 5A2OA 1JLIA 1BGDA 4A3KD 1Z92A 5FLMD 3NPZA 5FUCA 4YBQA 1HULA 3HOWD 4NI9A 4A3BD 4JR9A 1BUYA 1N1FA 2INTA 4Z5RD 4Q65A 4BBRD 4NEMA 1PV7A 4DKDA 1F45B 5C65A 1CSGA 5C3ED 5C4XD 1J7VL 5EQHA 3MZGA 3WCYI 4D2BA 4J05A 3B5KA 3NCBA 4U4WA 3H0GD 4IKVA 2O26A 1D9GA 1Y6KL 2IL6A 3O7QA 1PV6A 2XQBA 5EQGA 1PW6A 1HUWA 3N06A 4NI7A 1WU3I 1QVNA 3PIVA 4IU8A 2LMSA 1Y1WD 4XNIA 1RCBA 3IRHA 3DUHC 4CNIC 1Y14A 4YUEC 2JA7D 4A3MD 1LKIA 3HOXD 2D9QA 4ZF7A 1INRA 4ZS7A 1M49A 3OQ3A 1FG9A 1HGUA 4GBYA 2Q98A 4EXPA 3HHRA 2VUMD 3BPNA 4A93D 3I4MD 4BXXD 3LB6A 2CYKA 4IU9A 3HHCA 4YB9D 1BP3A 3L5XA 4A3ED 1M48A 2JA5D 4APSA 4NN6A 4WRLB 2H24A 3HOUD 1GNCA 5KNHI 2R92D 1EERA 4RS1A 3DI3A 1HIJA 5LQBA 1WCMD 3NCEA 4NEJA 1ILKA 4QIQA 3UF2A 2Z3RA 1CD9A 3D87A 4NKQC 1Y6NL 3PO2D 4EXNA 4TPGA 1P9MB 4U4VA 1NBPA 5D28B 1M47A 3QAZA 5IYDD 1M4AA 2ERJD 4LEPA 2D48A
chains in the Genus database with same CATH topology
1BBNA 1PW6A 1VLKA 3DLQI 3HMXB 1HUWA 4DKEA 3OG4A 1M4BA 3N06A 4NI7A 2Q7NB 1ITIA 1EMRA 2GMFA 1WU3I 1QVNA 2HYMB 1ITMA 2Q14A 3PIVA 1CNT1 1V7NV 3QWRB 1PVHB 4GRWA 5D72A 3PO3D 1YKBA 2JA6D 1AU1A 1B5LA 4J4LC 2R7ZD 3VA2A 1CYLA 1CN4C 2LMSA 4I77Z 5D71A 1Y1WD 3QB1A 2B63D 4FA8E 1GA3A 2L3OA 3NCFA 1RCBA 3IRHA 3DUHC 2JA8D 1ETEA 5IP9D 4CNIC 3DI2A 3S9DA 1Y14A 3D85C 3I4ND 4BY1D 3LB6B 3G9VB 5C7XA 4YUEC 4A3DD 1IARA 1RW5A 2JA7D 2O6IA 4DKCA 1IK0A 4A3MD 1FYHA 1LKIA 3UEZE 2D9QA 4ZF7A 3HOXD 1PY2A 3AYHA 4A3ID 1INRA 4ZS7A 4A3FD 2B8YA 1M49A 3OG6A 3OQ3A 1FG9A 3Q1SI 4GS7A 1HGUA 2PSMA 4O9HA 3INKC 3H3VE 1BCNA 4MHLA 2C35A 2Q98A 1SCFA 3BPLA 4EXPA 1M4CA 2R93D 1V7MV 4YQXA 2O27A 1HIKA 3HHRA 1A22A 2KZ1A 3L5WI 3UF5A 2VUMD 3QT2C 3BPNA 1IJZA 2Z3QA 3BESL 5D22A 1Y1VD 3I4MD 4A93D 1ALUA 5IYCD 4BXXD 1EVSA 4O6KA 5IP7D 4A3CD 1JLIA 1Z7CA 2B90A 3LB6A 1LQSL 1BGDA 2CYKA 3N0PA 5FHXA 4A3KD 1Z92A 2B8ZA 4BY7D 3HHCA 2L3YA 2LAGA 3FKID 5FLMD 1BP3A 4A3GD 3BPOA 1ITFA 4X51A 3D48P 3L5XA 5D70A 3NPZA 4PS4A 5FUCA 1PGRA 4A3ED 1M48A 4A3JD 2JA5D 1HULA 1Y6ML 3EJJA 4NN6A 3HOYD 3HOWD 4NI9A 4A3BD 4A3LD 2B5IA 1BUYA 4WRLB 2H24A 1AX8A 1N1FA 3HOUD 1EKUA 1HWHA 2INTA 4Z5RD 1M4RA 1GNCA 5KNHI 2R92D 4BBRD 1RHGA 3DGCL 3QB7A 1EERA 4NEMA 4RS1A 5L6YC 2B91A 1RFBA 3DI3A 1HIJA 4YPGC 1WCMD 5LQBA 1BGEA 1HWGA 3NCEA 3HOVD 4DKDA 1F45B 1A7MA 1IRLA 4NEJA 5IYBD 1CSGA 1I1RB 5C3ED 1ILKA 5TS9A 5C4XD 1J7VL 4NN5A 3MZGA 3PIWA 3UF2A 3WCYI 2E9WC 2Z3RA 1CD9A 1EXZA 3D87A 4NKQC 1KF9A 1Y6NL 3B5KA 3NCBA 3PO2D 3SE4B 4EXNA 4YDYI 4BBSD 2B8UA 1HZIA 2OQPA 3H0GD 1P9MB 1BGCA 3HOZD 1D9CA 1NBPA 5E4EA 1F6FA 1AXIA 2O26A 3EW3A 5D28B 1M47A 3QAZA 1ITLA 4LRLA 3UX9A 2B8XA 5C44D 1D9GA 1LK3A 4DKFA 5IYDD 3G6DA 2ILKA 1Y6KL 1M4AA 4NN7A 2IL6A 1IL6A 3NCCA 4DOHA 2ERJD 3TGXB 2D48A 2XQBA 3SE3B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3M D;  3HOX D;  3AYH A;  4A3I D;  4A3E D;  4A3F D;  3PO3 D;  4A3J D;  2JA5 D;  3H3V E;  3PO2 D;  3HOY D;  3HOW D;  4A3B D;  4A3L D;  2C35 A;  4BBS D;  2R93 D;  2JA6 D;  3H0G D;  3HOU D;  3HOZ D;  2R7Z D;  2VUM D;  2B63 D;  2R92 D;  4BBR D;  1Y1W D;  4A93 D;  3I4M D;  2JA8 D;  1Y1V D;  4BXX D;  5IYC D;  1WCM D;  5IP9 D;  5IP7 D;  4A3C D;  3HOV D;  1Y14 A;  5C44 D;  3I4N D;  4BY1 D;  4A3K D;  5IYD D;  5IYB D;  4A3D D;  2JA7 D;  4BY7 D;  5C3E D;  5FLM D;  3FKI D;  5C4X D;  4A3G D; 
#chains in the Genus database with same CATH topology
 3DLQ I;  3OG4 A;  1M4B A;  1EMR A;  1ITM A;  4D2D A;  1CNT 1;  1V7N V;  1PVH B;  4GRW A;  5D72 A;  4GBZ A;  1AU1 A;  1B5L A;  4J4L C;  1CN4 C;  5D71 A;  4I77 Z;  2L3O A;  3NCF A;  1ETE A;  4BY1 D;  3LB6 B;  4IKW A;  4A3D D;  1RW5 A;  4DKC A;  3UEZ E;  3AYH A;  4A3F D;  3Q1S I;  3H3V E;  1SCF A;  4YQX A;  2O27 A;  4W6V A;  1HIK A;  2Y5Y A;  1PW4 A;  1A22 A;  2KZ1 A;  3UF5 A;  5IP7 D;  4A3C D;  1Z7C A;  1LQS L;  3N0P A;  2L3Y A;  3FKI D;  4A3G D;  3BPO A;  1ITF A;  5D70 A;  4A3J D;  4JRE A;  1Y6M L;  2B5I A;  1EKU A;  1HWH A;  4GC0 A;  1M4R A;  3QB7 A;  3DGC L;  5L6Y C;  4IKY A;  1A7M A;  5IYB D;  4JA3 A;  5TS9 A;  5GXB A;  2V8N A;  3SE4 B;  4YDY I;  4BBS D;  1HZI A;  1D9C A;  1F6F A;  3EW3 A;  1ITL A;  4LRL A;  3UX9 A;  2B8X A;  4IKX A;  1LK3 A;  4DKF A;  4NN7 A;  1IL6 A;  3WDO A;  4DOH A;  3TGX B;  1BBN A;  1VLK A;  4DKE A;  1ITI A;  2Q7N B;  2Q14 A;  3QWR B;  4ZYR A;  4ZWB A;  1CYL A;  1GA3 A;  3S9D A;  3D85 C;  4LDS A;  4TPH A;  2O6I A;  4A3I D;  3PO3 D;  4O9H A;  2B8Y A;  4GS7 A;  2PSM A;  2C35 A;  3BPL A;  1M4C A;  1V7M V;  4TPJ A;  3L5W I;  1IJZ A;  2Z3Q A;  4O6K A;  2B90 A;  5FHX A;  2B8Z A;  4ZWC A;  4BY7 D;  2LAG A;  4U4T A;  4X51 A;  3D48 P;  3O7P A;  4PS4 A;  1PGR A;  3EJJ A;  3HOY D;  4A3L D;  5D6K A;  1AX8 A;  1RHG A;  2B91 A;  1RFB A;  4YPG C;  4OH3 A;  1BGE A;  1HWG A;  3HOV D;  1IRL A;  5D58 A;  1I1R B;  4NN5 A;  3PIW A;  2E9W C;  1EXZ A;  1KF9 A;  4D2C A;  2B8U A;  2OQP A;  5EQI A;  1BGC A;  3HOZ D;  4IKZ A;  2CFQ A;  5E4E A;  1AXI A;  5A2N A;  5C44 D;  3G6D A;  2ILK A;  5D59 A;  3NCC A;  3SE3 B;  3HMX B;  4UVM A;  4XNJ A;  2HYM B;  2GMF A;  1YKB A;  2JA6 D;  4PYP A;  2R7Z D;  3VA2 A;  2B63 D;  3QB1 A;  4FA8 E;  2JA8 D;  2XUT A;  5IP9 D;  3DI2 A;  3I4N D;  3G9V B;  5C7X A;  1IAR A;  1FYH A;  1PY2 A;  1IK0 A;  3OG6 A;  1BCN A;  2CFP A;  3INK C;  4MHL A;  2R93 D;  4ZW9 A;  4OAA A;  3QT2 C;  3BES L;  5D22 A;  1Y1V D;  1ALU A;  5IYC D;  1EVS A;  5A2O A;  1JLI A;  1BGD A;  4A3K D;  1Z92 A;  5FLM D;  3NPZ A;  5FUC A;  4YBQ A;  1HUL A;  3HOW D;  4NI9 A;  4A3B D;  4JR9 A;  1BUY A;  1N1F A;  2INT A;  4Z5R D;  4Q65 A;  4BBR D;  4NEM A;  1PV7 A;  4DKD A;  1F45 B;  5C65 A;  1CSG A;  5C3E D;  5C4X D;  1J7V L;  5EQH A;  3MZG A;  3WCY I;  4D2B A;  4J05 A;  3B5K A;  3NCB A;  4U4W A;  3H0G D;  4IKV A;  2O26 A;  1D9G A;  1Y6K L;  2IL6 A;  3O7Q A;  1PV6 A;  2XQB A;  5EQG A;  1PW6 A;  1HUW A;  3N06 A;  4NI7 A;  1WU3 I;  1QVN A;  3PIV A;  4IU8 A;  2LMS A;  1Y1W D;  4XNI A;  1RCB A;  3IRH A;  3DUH C;  4CNI C;  1Y14 A;  4YUE C;  2JA7 D;  4A3M D;  1LKI A;  3HOX D;  2D9Q A;  4ZF7 A;  1INR A;  4ZS7 A;  1M49 A;  3OQ3 A;  1FG9 A;  1HGU A;  4GBY A;  2Q98 A;  4EXP A;  3HHR A;  2VUM D;  3BPN A;  4A93 D;  3I4M D;  4BXX D;  3LB6 A;  2CYK A;  4IU9 A;  3HHC A;  4YB9 D;  1BP3 A;  3L5X A;  4A3E D;  1M48 A;  2JA5 D;  4APS A;  4NN6 A;  4WRL B;  2H24 A;  3HOU D;  1GNC A;  5KNH I;  2R92 D;  1EER A;  4RS1 A;  3DI3 A;  1HIJ A;  5LQB A;  1WCM D;  3NCE A;  4NEJ A;  1ILK A;  4QIQ A;  3UF2 A;  2Z3R A;  1CD9 A;  3D87 A;  4NKQ C;  1Y6N L;  3PO2 D;  4EXN A;  4TPG A;  1P9M B;  4U4V A;  1NBP A;  5D28 B;  1M47 A;  3QAZ A;  5IYD D;  1M4A A;  2ERJ D;  4LEP A;  2D48 A; 
#chains in the Genus database with same CATH homology
 1BBN A;  1PW6 A;  1VLK A;  3DLQ I;  3HMX B;  1HUW A;  4DKE A;  3OG4 A;  1M4B A;  3N06 A;  4NI7 A;  2Q7N B;  1ITI A;  1EMR A;  2GMF A;  1WU3 I;  1QVN A;  2HYM B;  1ITM A;  2Q14 A;  3PIV A;  1CNT 1;  1V7N V;  3QWR B;  1PVH B;  4GRW A;  5D72 A;  3PO3 D;  1YKB A;  2JA6 D;  1AU1 A;  1B5L A;  4J4L C;  2R7Z D;  3VA2 A;  1CYL A;  1CN4 C;  2LMS A;  4I77 Z;  5D71 A;  1Y1W D;  3QB1 A;  2B63 D;  4FA8 E;  1GA3 A;  2L3O A;  3NCF A;  1RCB A;  3IRH A;  3DUH C;  2JA8 D;  1ETE A;  5IP9 D;  4CNI C;  3DI2 A;  3S9D A;  1Y14 A;  3D85 C;  3I4N D;  4BY1 D;  3LB6 B;  3G9V B;  5C7X A;  4YUE C;  4A3D D;  1IAR A;  1RW5 A;  2JA7 D;  2O6I A;  4DKC A;  1IK0 A;  4A3M D;  1FYH A;  1LKI A;  3UEZ E;  2D9Q A;  4ZF7 A;  3HOX D;  1PY2 A;  3AYH A;  4A3I D;  1INR A;  4ZS7 A;  4A3F D;  2B8Y A;  1M49 A;  3OG6 A;  3OQ3 A;  1FG9 A;  3Q1S I;  4GS7 A;  1HGU A;  2PSM A;  4O9H A;  3INK C;  3H3V E;  1BCN A;  4MHL A;  2C35 A;  2Q98 A;  1SCF A;  3BPL A;  4EXP A;  1M4C A;  2R93 D;  1V7M V;  4YQX A;  2O27 A;  1HIK A;  3HHR A;  1A22 A;  2KZ1 A;  3L5W I;  3UF5 A;  2VUM D;  3QT2 C;  3BPN A;  1IJZ A;  2Z3Q A;  3BES L;  5D22 A;  1Y1V D;  3I4M D;  4A93 D;  1ALU A;  5IYC D;  4BXX D;  1EVS A;  4O6K A;  5IP7 D;  4A3C D;  1JLI A;  1Z7C A;  2B90 A;  3LB6 A;  1LQS L;  1BGD A;  2CYK A;  3N0P A;  5FHX A;  4A3K D;  1Z92 A;  2B8Z A;  4BY7 D;  3HHC A;  2L3Y A;  2LAG A;  3FKI D;  5FLM D;  1BP3 A;  4A3G D;  3BPO A;  1ITF A;  4X51 A;  3D48 P;  3L5X A;  5D70 A;  3NPZ A;  4PS4 A;  5FUC A;  1PGR A;  4A3E D;  1M48 A;  4A3J D;  2JA5 D;  1HUL A;  1Y6M L;  3EJJ A;  4NN6 A;  3HOY D;  3HOW D;  4NI9 A;  4A3B D;  4A3L D;  2B5I A;  1BUY A;  4WRL B;  2H24 A;  1AX8 A;  1N1F A;  3HOU D;  1EKU A;  1HWH A;  2INT A;  4Z5R D;  1M4R A;  1GNC A;  5KNH I;  2R92 D;  4BBR D;  1RHG A;  3DGC L;  3QB7 A;  1EER A;  4NEM A;  4RS1 A;  5L6Y C;  2B91 A;  1RFB A;  3DI3 A;  1HIJ A;  4YPG C;  1WCM D;  5LQB A;  1BGE A;  1HWG A;  3NCE A;  3HOV D;  4DKD A;  1F45 B;  1A7M A;  1IRL A;  4NEJ A;  5IYB D;  1CSG A;  1I1R B;  5C3E D;  1ILK A;  5TS9 A;  5C4X D;  1J7V L;  4NN5 A;  3MZG A;  3PIW A;  3UF2 A;  3WCY I;  2E9W C;  2Z3R A;  1CD9 A;  1EXZ A;  3D87 A;  4NKQ C;  1KF9 A;  1Y6N L;  3B5K A;  3NCB A;  3PO2 D;  3SE4 B;  4EXN A;  4YDY I;  4BBS D;  2B8U A;  1HZI A;  2OQP A;  3H0G D;  1P9M B;  1BGC A;  3HOZ D;  1D9C A;  1NBP A;  5E4E A;  1F6F A;  1AXI A;  2O26 A;  3EW3 A;  5D28 B;  1M47 A;  3QAZ A;  1ITL A;  4LRL A;  3UX9 A;  2B8X A;  5C44 D;  1D9G A;  1LK3 A;  4DKF A;  5IYD D;  3G6D A;  2ILK A;  1Y6K L;  1M4A A;  4NN7 A;  2IL6 A;  1IL6 A;  3NCC A;  4DOH A;  2ERJ D;  3TGX B;  2D48 A;  2XQB A;  3SE3 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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