4A93D

Rna polymerase ii elongation complex containing a cpd lesion
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
219
structure length
178
Chain Sequence
VSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1
publication title Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
pubmed doi rcsb
total genus 49
structure length 178
sequence length 219
ec nomenclature
pdb deposition date 2011-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4a93D02
4A3ID 1Y1WD 5IP9D 5IYBD 3HOUD 3I4ND 4BBSD 3PO3D 5C44D 3HOVD 3HOZD 3PO2D 4A3CD 4A3JD 2JA5D 2R7ZD 3H3VE 4A3MD 3HOYD 4A3DD 5IP7D 5IYDD 4BY1D 1WCMD 2VUMD 4BY7D 4BXXD 4A3GD 2JA8D 4A3LD 4A3KD 3I4MD 3H0GD 2JA7D 2C35A 3AYHA 3HOXD 3HOWD 5C3ED 2JA6D 4A3FD 5IYCD 1Y1VD 2R92D 2R93D 1Y14A 4BBRD 4A3BD 2B63D 4A3ED 5C4XD 4A93D 5FLMD 3FKID
chains in the Genus database with same CATH superfamily
4J4LC 5D6KA 1CD9A 3BPOA 3LB6B 3H3VE 3UF5A 4A3DD 1AX8A 3QB1A 1WCMD 2L3OA 5A2NA 1EXZA 4A3LD 3DUHC 3H0GD 2JA7D 4A3FD 1Y1VD 4DKEA 1PV7A 4BBRD 2B63D 4UVMA 4YBQA 4YPGC 1ETEA 3OQ3A 5LQBA 5IYBD 1NBPA 1M48A 3O7QA 1ITLA 2ILKA 1M47A 4U4VA 1IK0A 3HHRA 4LRLA 3SE4B 4D2DA 2V8NA 5D28B 1IRLA 3FKID 1ITMA 4EXPA 3HOUD 2Q98A 4FA8E 3QWRB 4O6KA 5GXBA 3UF2A 4ZWBA 4IU8A 4DOHA 1IL6A 3TGXB 4EXNA 2O6IA 2Q14A 1JLIA 1PVHB 1Y1WD 3NCCA 4GRWA 4CNIC 3SE3B 3HOVD 3DI2A 4ZF7A 2Q7NB 1RW5A 5D70A 3HMXB 3MZGA 3HOWD 3PIVA 5IP9D 1AU1A 5EQGA 1B5LA 5IP7D 1GNCA 5D58A 4MHLA 3QT2C 1M4RA 1Y6KL 1ILKA 2R93D 2D48A 5IYCD 4A3BD 2B91A 2INTA 4PYPA 4NI9A 3NCFA 1WU3I 1SCFA 1J7VL 1V7MV 4DKCA 4D2CA 1BGDA 5C65A 3OG4A 4LEPA 2JA8D 4NEMA 2IL6A 4NEJA 1VLKA 2C35A 1LQSL 2CYKA 2CFQA 1D9GA 3G9VB 1Y14A 4NN7A 3QB7A 3L5XA 1PW6A 5C44D 3PO2D 4Z5RD 2B90A 1F6FA 4J05A 1IJZA 1CN4C 3I4MD 3HHCA 1HIJA 1YKBA 3PIWA 2XUTA 4LDSA 4A3ED 2LAGA 4U4TA 4OH3A 4YQXA 4XNIA 2JA5D 4YUEC 1M49A 4IKZA 5C7XA 1RCBA 5TS9A 1IARA 4U4WA 3N06A 4GBYA 2JA6D 5C4XD 4NKQC 1CSGA 4XNJA 4WRLB 2KZ1A 4X51A 3PO3D 5D22A 1EMRA 3BPLA 2D9QA 1INRA 1RFBA 3OG6A 1Z92A 4GC0A 4W6VA 3INKC 1HULA 5D72A 1KF9A 2HYMB 1BBNA 1HGUA 1ITFA 1F45B 1I1RB 1AXIA 1GA3A 2E9WC 1RHGA 1HIKA 4TPGA 1CYLA 1ALUA 3N0PA 4BXXD 2O27A 4A3GD 4JA3A 1PV6A 4Q65A 3NCEA 2CFPA 4IU9A 4JR9A 4PS4A 2PSMA 4TPHA 3IRHA 3VA2A 3BESL 4ZYRA 3L5WI 1V7NV 4ZS7A 4QIQA 4GS7A 1BUYA 1QVNA 4IKYA 4JREA 4RS1A 4YB9D 5D59A 3DLQI 3LB6A 3UX9A 1BGEA 1LKIA 1EVSA 2B8ZA 5EQIA 3HOZD 4TPJA 1FG9A 3DGCL 3WDOA 1M4CA 3BPNA 3UEZE 3D48P 5L6YC 3WCYI 1EKUA 3AYHA 3HOXD 5FUCA 3D87A 1ITIA 4A3ID 1Z7CA 3EW3A 1HWHA 2H24A 3EJJA 2R7ZD 4NI7A 2L3YA 4BY7D 1HWGA 4DKDA 1CNT1 3DI3A 4D2BA 3B5KA 4YDYI 4OAAA 2GMFA 2B8UA 4O9HA 1Y6NL 1BGCA 2ERJD 2OQPA 4A93D 5A2OA 1BCNA 1A22A 4I77Z 1LK3A 3D85C 5KNHI 4BY1D 4NN6A 1EERA 4ZW9A 1HUWA 3NPZA 2LMSA 2Y5YA 4NN5A 2R92D 2B8YA 3O7PA 2Z3QA 3QAZA 4BBSD 1FYHA 1A7MA 3HOYD 5D71A 4ZWCA 5IYDD 3S9DA 1HZIA 1BP3A 4IKVA 4A3KD 1P9MB 5E4EA 5EQHA 2XQBA 4GBZA 1N1FA 5FLMD 3I4ND 4DKFA 4A3CD 2B5IA 2B8XA 4A3JD 1D9CA 1Y6ML 4A3MD 1M4BA 4IKXA 2Z3RA 1PGRA 3G6DA 1PY2A 2VUMD 4IKWA 5FHXA 2O26A 5C3ED 1M4AA 3Q1SI 1PW4A 4APSA 3NCBA
chains in the Genus database with same CATH topology
4J4LC 4A3ID 1Z7CA 3EW3A 5IP9D 4WRLB 2KZ1A 1HWHA 4X51A 3PO3D 5D22A 1EMRA 2H24A 1CD9A 3EJJA 1AU1A 3BPOA 1B5LA 3LB6B 3H3VE 3BPLA 2R7ZD 3UF5A 4A3DD 1AX8A 2D9QA 3QB1A 5IP7D 1GNCA 1WCMD 1INRA 2L3OA 4NI7A 1EXZA 2L3YA 1RFBA 1HWGA 4BY7D 4DKDA 1CNT1 4MHLA 3OG6A 1Z92A 4A3LD 3QT2C 3INKC 3DI3A 1HULA 1M4RA 3DUHC 4YDYI 3B5KA 3H0GD 5D72A 2JA7D 2GMFA 1KF9A 1Y6KL 2B8UA 2HYMB 1ILKA 1BBNA 4O9HA 2R93D 4A3FD 1HGUA 1Y1VD 1Y6NL 2D48A 1BGCA 4BBRD 4DKEA 5IYCD 1ITFA 4A3BD 2B63D 2ERJD 2B91A 2OQPA 1F45B 4YPGC 1I1RB 1ETEA 2INTA 1AXIA 3OQ3A 5LQBA 4A93D 5IYBD 1NBPA 1BCNA 1GA3A 1A22A 1M48A 4I77Z 4NI9A 3NCFA 2E9WC 1LK3A 1WU3I 1ITLA 3D85C 2ILKA 5KNHI 1SCFA 1J7VL 1V7MV 1RHGA 4DKCA 1HIKA 4NN6A 4BY1D 1CYLA 1M47A 1ALUA 1BGDA 1EERA 1IK0A 3N0PA 3OG4A 4BXXD 1HUWA 2O27A 4A3GD 2JA8D 3HHRA 4LRLA 4NEMA 3NCEA 3SE4B 3NPZA 2IL6A 2LMSA 1VLKA 4NEJA 2C35A 1LQSL 2CYKA 4NN5A 1D9GA 2R92D 2B8YA 3G9VB 1Y14A 4PS4A 5D28B 2PSMA 2Z3QA 4NN7A 1IRLA 3FKID 1ITMA 3QAZA 4EXPA 3IRHA 4BBSD 3HOUD 2Q98A 3VA2A 4FA8E 1FYHA 3BESL 1A7MA 3QB7A 3L5XA 1PW6A 3L5WI 3QWRB 1V7NV 4O6KA 4ZS7A 5C44D 3PO2D 4Z5RD 3HOYD 2B90A 1F6FA 5D71A 3NCBA 5IYDD 3UF2A 4GS7A 1BUYA 3S9DA 1IJZA 1CN4C 1QVNA 1HZIA 4RS1A 1BP3A 4DOHA 4A3KD 3I4MD 3DLQI 3HHCA 1IL6A 1HIJA 3LB6A 3TGXB 1P9MB 4EXNA 1YKBA 5E4EA 3PIWA 3UX9A 2O6IA 2Q14A 1BGEA 1JLIA 1N1FA 1LKIA 4A3ED 1PVHB 1EVSA 5FLMD 2B8ZA 2LAGA 1Y1WD 3NCCA 4YQXA 4DKFA 3I4ND 4GRWA 4CNIC 3SE3B 3HOVD 3HOZD 4A3CD 2B5IA 2B8XA 4A3JD 2JA5D 1FG9A 3DI2A 4YUEC 1D9CA 1Y6ML 1M49A 3DGCL 4A3MD 4ZF7A 1M4BA 2Z3RA 1PGRA 3G6DA 1PY2A 2VUMD 1M4CA 3BPNA 3UEZE 2Q7NB 3D48P 5C7XA 1RCBA 4NKQC 5FHXA 5TS9A 1IARA 1RW5A 2O26A 5D70A 1EKUA 3WCYI 5L6YC 3N06A 3AYHA 3HMXB 3MZGA 3HOXD 5FUCA 3D87A 5C3ED 3HOWD 1M4AA 2JA6D 1ITIA 3Q1SI 3PIVA 5C4XD 2XQBA 1CSGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3I D;  1Y1W D;  5IP9 D;  5IYB D;  3HOU D;  3I4N D;  4BBS D;  3PO3 D;  5C44 D;  3HOV D;  3HOZ D;  3PO2 D;  4A3C D;  4A3J D;  2JA5 D;  2R7Z D;  3H3V E;  4A3M D;  3HOY D;  4A3D D;  5IP7 D;  5IYD D;  4BY1 D;  1WCM D;  2VUM D;  4BY7 D;  4BXX D;  4A3G D;  2JA8 D;  4A3L D;  4A3K D;  3I4M D;  3H0G D;  2JA7 D;  2C35 A;  3AYH A;  3HOX D;  3HOW D;  5C3E D;  2JA6 D;  4A3F D;  5IYC D;  1Y1V D;  2R92 D;  2R93 D;  1Y14 A;  4BBR D;  4A3B D;  2B63 D;  4A3E D;  5C4X D;  4A93 D;  5FLM D;  3FKI D; 
#chains in the Genus database with same CATH topology
 4J4L C;  5D6K A;  1CD9 A;  3BPO A;  3LB6 B;  3H3V E;  3UF5 A;  4A3D D;  1AX8 A;  3QB1 A;  1WCM D;  2L3O A;  5A2N A;  1EXZ A;  4A3L D;  3DUH C;  3H0G D;  2JA7 D;  4A3F D;  1Y1V D;  4DKE A;  1PV7 A;  4BBR D;  2B63 D;  4UVM A;  4YBQ A;  4YPG C;  1ETE A;  3OQ3 A;  5LQB A;  5IYB D;  1NBP A;  1M48 A;  3O7Q A;  1ITL A;  2ILK A;  1M47 A;  4U4V A;  1IK0 A;  3HHR A;  4LRL A;  3SE4 B;  4D2D A;  2V8N A;  5D28 B;  1IRL A;  3FKI D;  1ITM A;  4EXP A;  3HOU D;  2Q98 A;  4FA8 E;  3QWR B;  4O6K A;  5GXB A;  3UF2 A;  4ZWB A;  4IU8 A;  4DOH A;  1IL6 A;  3TGX B;  4EXN A;  2O6I A;  2Q14 A;  1JLI A;  1PVH B;  1Y1W D;  3NCC A;  4GRW A;  4CNI C;  3SE3 B;  3HOV D;  3DI2 A;  4ZF7 A;  2Q7N B;  1RW5 A;  5D70 A;  3HMX B;  3MZG A;  3HOW D;  3PIV A;  5IP9 D;  1AU1 A;  5EQG A;  1B5L A;  5IP7 D;  1GNC A;  5D58 A;  4MHL A;  3QT2 C;  1M4R A;  1Y6K L;  1ILK A;  2R93 D;  2D48 A;  5IYC D;  4A3B D;  2B91 A;  2INT A;  4PYP A;  4NI9 A;  3NCF A;  1WU3 I;  1SCF A;  1J7V L;  1V7M V;  4DKC A;  4D2C A;  1BGD A;  5C65 A;  3OG4 A;  4LEP A;  2JA8 D;  4NEM A;  2IL6 A;  4NEJ A;  1VLK A;  2C35 A;  1LQS L;  2CYK A;  2CFQ A;  1D9G A;  3G9V B;  1Y14 A;  4NN7 A;  3QB7 A;  3L5X A;  1PW6 A;  5C44 D;  3PO2 D;  4Z5R D;  2B90 A;  1F6F A;  4J05 A;  1IJZ A;  1CN4 C;  3I4M D;  3HHC A;  1HIJ A;  1YKB A;  3PIW A;  2XUT A;  4LDS A;  4A3E D;  2LAG A;  4U4T A;  4OH3 A;  4YQX A;  4XNI A;  2JA5 D;  4YUE C;  1M49 A;  4IKZ A;  5C7X A;  1RCB A;  5TS9 A;  1IAR A;  4U4W A;  3N06 A;  4GBY A;  2JA6 D;  5C4X D;  4NKQ C;  1CSG A;  4XNJ A;  4WRL B;  2KZ1 A;  4X51 A;  3PO3 D;  5D22 A;  1EMR A;  3BPL A;  2D9Q A;  1INR A;  1RFB A;  3OG6 A;  1Z92 A;  4GC0 A;  4W6V A;  3INK C;  1HUL A;  5D72 A;  1KF9 A;  2HYM B;  1BBN A;  1HGU A;  1ITF A;  1F45 B;  1I1R B;  1AXI A;  1GA3 A;  2E9W C;  1RHG A;  1HIK A;  4TPG A;  1CYL A;  1ALU A;  3N0P A;  4BXX D;  2O27 A;  4A3G D;  4JA3 A;  1PV6 A;  4Q65 A;  3NCE A;  2CFP A;  4IU9 A;  4JR9 A;  4PS4 A;  2PSM A;  4TPH A;  3IRH A;  3VA2 A;  3BES L;  4ZYR A;  3L5W I;  1V7N V;  4ZS7 A;  4QIQ A;  4GS7 A;  1BUY A;  1QVN A;  4IKY A;  4JRE A;  4RS1 A;  4YB9 D;  5D59 A;  3DLQ I;  3LB6 A;  3UX9 A;  1BGE A;  1LKI A;  1EVS A;  2B8Z A;  5EQI A;  3HOZ D;  4TPJ A;  1FG9 A;  3DGC L;  3WDO A;  1M4C A;  3BPN A;  3UEZ E;  3D48 P;  5L6Y C;  3WCY I;  1EKU A;  3AYH A;  3HOX D;  5FUC A;  3D87 A;  1ITI A;  4A3I D;  1Z7C A;  3EW3 A;  1HWH A;  2H24 A;  3EJJ A;  2R7Z D;  4NI7 A;  2L3Y A;  4BY7 D;  1HWG A;  4DKD A;  1CNT 1;  3DI3 A;  4D2B A;  3B5K A;  4YDY I;  4OAA A;  2GMF A;  2B8U A;  4O9H A;  1Y6N L;  1BGC A;  2ERJ D;  2OQP A;  4A93 D;  5A2O A;  1BCN A;  1A22 A;  4I77 Z;  1LK3 A;  3D85 C;  5KNH I;  4BY1 D;  4NN6 A;  1EER A;  4ZW9 A;  1HUW A;  3NPZ A;  2LMS A;  2Y5Y A;  4NN5 A;  2R92 D;  2B8Y A;  3O7P A;  2Z3Q A;  3QAZ A;  4BBS D;  1FYH A;  1A7M A;  3HOY D;  5D71 A;  4ZWC A;  5IYD D;  3S9D A;  1HZI A;  1BP3 A;  4IKV A;  4A3K D;  1P9M B;  5E4E A;  5EQH A;  2XQB A;  4GBZ A;  1N1F A;  5FLM D;  3I4N D;  4DKF A;  4A3C D;  2B5I A;  2B8X A;  4A3J D;  1D9C A;  1Y6M L;  4A3M D;  1M4B A;  4IKX A;  2Z3R A;  1PGR A;  3G6D A;  1PY2 A;  2VUM D;  4IKW A;  5FHX A;  2O26 A;  5C3E D;  1M4A A;  3Q1S I;  1PW4 A;  4APS A;  3NCB A; 
#chains in the Genus database with same CATH homology
 4J4L C;  4A3I D;  1Z7C A;  3EW3 A;  5IP9 D;  4WRL B;  2KZ1 A;  1HWH A;  4X51 A;  3PO3 D;  5D22 A;  1EMR A;  2H24 A;  1CD9 A;  3EJJ A;  1AU1 A;  3BPO A;  1B5L A;  3LB6 B;  3H3V E;  3BPL A;  2R7Z D;  3UF5 A;  4A3D D;  1AX8 A;  2D9Q A;  3QB1 A;  5IP7 D;  1GNC A;  1WCM D;  1INR A;  2L3O A;  4NI7 A;  1EXZ A;  2L3Y A;  1RFB A;  1HWG A;  4BY7 D;  4DKD A;  1CNT 1;  4MHL A;  3OG6 A;  1Z92 A;  4A3L D;  3QT2 C;  3INK C;  3DI3 A;  1HUL A;  1M4R A;  3DUH C;  4YDY I;  3B5K A;  3H0G D;  5D72 A;  2JA7 D;  2GMF A;  1KF9 A;  1Y6K L;  2B8U A;  2HYM B;  1ILK A;  1BBN A;  4O9H A;  2R93 D;  4A3F D;  1HGU A;  1Y1V D;  1Y6N L;  2D48 A;  1BGC A;  4BBR D;  4DKE A;  5IYC D;  1ITF A;  4A3B D;  2B63 D;  2ERJ D;  2B91 A;  2OQP A;  1F45 B;  4YPG C;  1I1R B;  1ETE A;  2INT A;  1AXI A;  3OQ3 A;  5LQB A;  4A93 D;  5IYB D;  1NBP A;  1BCN A;  1GA3 A;  1A22 A;  1M48 A;  4I77 Z;  4NI9 A;  3NCF A;  2E9W C;  1LK3 A;  1WU3 I;  1ITL A;  3D85 C;  2ILK A;  5KNH I;  1SCF A;  1J7V L;  1V7M V;  1RHG A;  4DKC A;  1HIK A;  4NN6 A;  4BY1 D;  1CYL A;  1M47 A;  1ALU A;  1BGD A;  1EER A;  1IK0 A;  3N0P A;  3OG4 A;  4BXX D;  1HUW A;  2O27 A;  4A3G D;  2JA8 D;  3HHR A;  4LRL A;  4NEM A;  3NCE A;  3SE4 B;  3NPZ A;  2IL6 A;  2LMS A;  1VLK A;  4NEJ A;  2C35 A;  1LQS L;  2CYK A;  4NN5 A;  1D9G A;  2R92 D;  2B8Y A;  3G9V B;  1Y14 A;  4PS4 A;  5D28 B;  2PSM A;  2Z3Q A;  4NN7 A;  1IRL A;  3FKI D;  1ITM A;  3QAZ A;  4EXP A;  3IRH A;  4BBS D;  3HOU D;  2Q98 A;  3VA2 A;  4FA8 E;  1FYH A;  3BES L;  1A7M A;  3QB7 A;  3L5X A;  1PW6 A;  3L5W I;  3QWR B;  1V7N V;  4O6K A;  4ZS7 A;  5C44 D;  3PO2 D;  4Z5R D;  3HOY D;  2B90 A;  1F6F A;  5D71 A;  3NCB A;  5IYD D;  3UF2 A;  4GS7 A;  1BUY A;  3S9D A;  1IJZ A;  1CN4 C;  1QVN A;  1HZI A;  4RS1 A;  1BP3 A;  4DOH A;  4A3K D;  3I4M D;  3DLQ I;  3HHC A;  1IL6 A;  1HIJ A;  3LB6 A;  3TGX B;  1P9M B;  4EXN A;  1YKB A;  5E4E A;  3PIW A;  3UX9 A;  2O6I A;  2Q14 A;  1BGE A;  1JLI A;  1N1F A;  1LKI A;  4A3E D;  1PVH B;  1EVS A;  5FLM D;  2B8Z A;  2LAG A;  1Y1W D;  3NCC A;  4YQX A;  4DKF A;  3I4N D;  4GRW A;  4CNI C;  3SE3 B;  3HOV D;  3HOZ D;  4A3C D;  2B5I A;  2B8X A;  4A3J D;  2JA5 D;  1FG9 A;  3DI2 A;  4YUE C;  1D9C A;  1Y6M L;  1M49 A;  3DGC L;  4A3M D;  4ZF7 A;  1M4B A;  2Z3R A;  1PGR A;  3G6D A;  1PY2 A;  2VUM D;  1M4C A;  3BPN A;  3UEZ E;  2Q7N B;  3D48 P;  5C7X A;  1RCB A;  4NKQ C;  5FHX A;  5TS9 A;  1IAR A;  1RW5 A;  2O26 A;  5D70 A;  1EKU A;  3WCY I;  5L6Y C;  3N06 A;  3AYH A;  3HMX B;  3MZG A;  3HOX D;  5FUC A;  3D87 A;  5C3E D;  3HOW D;  1M4A A;  2JA6 D;  1ITI A;  3Q1S I;  3PIV A;  5C4X D;  2XQB A;  1CSG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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