4D2CA

Structure of a di peptide bound pot family peptide transporter
Total Genus 173
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
173
sequence length
467
structure length
429
Chain Sequence
KTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTAWSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
pubmed doi rcsb
molecule tags Transport protein
source organism Streptococcus thermophilus (strain atcc baa-250 / lmg 18311)
molecule keywords Di-or tripeptide:H+ symporter
total genus 173
structure length 429
sequence length 467
ec nomenclature
pdb deposition date 2014-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00854 PTR2 POT family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4d2cA00
4IU8A 4OH3A 4XNJA 4ZWCA 4IKZA 5D58A 4ZYRA 4UVMA 4LEPA 4U4VA 4TPJA 4APSA 4TPHA 4GC0A 5A2OA 3O7QA 4TPGA 2CFPA 4ZW9A 4IKXA 1PV7A 5A2NA 1PW4A 3WDOA 4D2BA 4U4WA 4GBZA 4D2CA 4QIQA 4IU9A 5EQHA 5C65A 4J05A 4W6VA 4YB9D 5EQIA 2Y5YA 4PYPA 4OAAA 4U4TA 4JR9A 4IKWA 5D6KA 4JA3A 4LDSA 4GBYA 4JREA 5D59A 1PV6A 4IKYA 4Q65A 5EQGA 2V8NA 4ZWBA 4XNIA 5GXBA 4YBQA 4IKVA 4D2DA 2XUTA 3O7PA 2CFQA
chains in the Genus database with same CATH superfamily
1PY2A 2B8XA 3HOWD 3L5WI 1V7NV 2O26A 4GS7A 3NPZA 1ITMA 3BPNA 1RHGA 3INKC 4A3DD 1GA3A 4YQXA 4Z5RD 4EXPA 1BGDA 1IK0A 4LRLA 4U4VA 4APSA 4GC0A 1RFBA 1INRA 1PW4A 4IU9A 4PYPA 4A3CD 1BGEA 3N0PA 1ILKA 2V8NA 5D22A 3QB1A 5D58A 4GRWA 4TPJA 1QVNA 4A3JD 3WCYI 4YB9D 1PW6A 4MHLA 1BGCA 3FKID 1CSGA 1HWGA 1ITFA 1EMRA 3O7PA 3PO2D 2B8UA 2L3YA 4NEJA 4TPHA 5A2OA 1BBNA 1PV7A 4ZF7A 1PGRA 1HWHA 5C65A 4J05A 5IYBD 5IP9D 1M4RA 4JR9A 1CYLA 1WCMD 2B8ZA 2ERJD 2XUTA 1AX8A 4A3ID 2JA7D 2Q14A 2ILKA 3HOYD 4PS4A 4NN7A 3HOUD 1Y6ML 4D2CA 2Y5YA 1Y1WD 4IKWA 5D6KA 1Y1VD 3L5XA 1HIKA 5D72A 5C44D 1YKBA 1N1FA 4XNIA 4BBSD 3WDOA 1ETEA 4ZWCA 3PO3D 3OG6A 5IYDD 2JA5D 2L3OA 2D9QA 1I1RB 2H24A 3AYHA 3HOZD 2Q7NB 4U4WA 1LKIA 2B91A 5IP7D 4BBRD 1AU1A 1PV6A 1HULA 4IKYA 1ALUA 2B63D 4ZS7A 1CNT1 3D48P 3NCCA 1BCNA 1D9CA 3PIVA 1GNCA 1EXZA 5FLMD 4QIQA 3Q1SI 1SCFA 5KNHI 3QAZA 1HUWA 3UEZE 4RS1A 1M4BA 2O27A 5C7XA 2KZ1A 5D28B 5GXBA 3NCEA 4J4LC 1Y14A 4NKQC 1EERA 3O7QA 1HGUA 4CNIC 2JA6D 4EXNA 1V7MV 4DKDA 3BESL 1NBPA 2O6IA 3HHCA 5L6YC 2CFQA 4XNJA 4NN5A 1A7MA 3DI2A 3OG4A 2Z3QA 4TPGA 2E9WC 4DKEA 2CFPA 1Z92A 3UF5A 2IL6A 3EJJA 3TGXB 1IARA 5EQHA 2B90A 4OAAA 4A93D 3MZGA 1CN4C 2INTA 1M48A 1M4AA 2GMFA 5IYCD 4ZYRA 4O9HA 2R92D 4ZW9A 4YUEC 5A2NA 3H0GD 2CYKA 2Q98A 3HMXB 4A3MD 2B8YA 4O6KA 1ITLA 3NCBA 1D9GA 1Z7CA 3D85C 4DOHA 1WU3I 5EQGA 1BUYA 4YBQA 4IKVA 1F45B 1FG9A 3VA2A 4X51A 4IKZA 1AXIA 5LQBA 3HOXD 5D71A 4D2BA 4BY1D 3I4MD 4JA3A 1J7VL 4JREA 2C35A 3N06A 2HYMB 4ZWBA 4YPGC 1EKUA 1FYHA 3NCFA 1BP3A 1KF9A 1Y6NL 4LEPA 2Z3RA 3DI3A 3PIWA 5FHXA 5TS9A 3QT2C 3B5KA 3H3VE 1F6FA 3OQ3A 4FA8E 5FUCA 3G6DA 1M4CA 3I4ND 3BPLA 1RCBA 3D87A 4NI9A 2JA8D 4IKXA 4GBZA 3UF2A 4W6VA 2XQBA 5D70A 5EQIA 3QB7A 4U4TA 3BPOA 4GBYA 2LMSA 3SE3B 4A3ED 3S9DA 2VUMD 1PVHB 4UVMA 1IRLA 2B5IA 3DGCL 3UX9A 4A3BD 4A3LD 1ITIA 2R7ZD 5C4XD 1M49A 4YDYI 3G9VB 3EW3A 1P9MB 1A22A 4I77Z 4NI7A 2PSMA 5E4EA 1RW5A 5D59A 3HHRA 4D2DA 1HIJA 5C3ED 4IU8A 2OQPA 2R93D 4DKFA 1B5LA 1CD9A 4WRLB 1JLIA 2LAGA 1IL6A 4NEMA 4LDSA 4DKCA 4BY7D 3LB6A 4Q65A 3SE4B 1LQSL 4OH3A 1HZIA 1IJZA 1VLKA 4NN6A 4A3GD 4A3KD 3HOVD 4BXXD 3DUHC 1Y6KL 1EVSA 3DLQI 3LB6B 4A3FD 2D48A 3IRHA 1M47A 1LK3A 3QWRB
chains in the Genus database with same CATH topology
4IU8A 4OH3A 4XNJA 4ZWCA 4IKZA 5D58A 4ZYRA 4UVMA 4LEPA 4U4VA 4TPJA 4APSA 4TPHA 4GC0A 5A2OA 3O7QA 4TPGA 2CFPA 4ZW9A 4IKXA 1PV7A 5A2NA 1PW4A 3WDOA 4D2BA 4U4WA 4GBZA 4D2CA 4QIQA 4IU9A 5EQHA 5C65A 4J05A 4W6VA 4YB9D 5EQIA 2Y5YA 4PYPA 4OAAA 4U4TA 4JR9A 4IKWA 5D6KA 4JA3A 4LDSA 4GBYA 4JREA 5D59A 1PV6A 4IKYA 4Q65A 5EQGA 2V8NA 4ZWBA 4XNIA 5GXBA 4YBQA 4IKVA 4D2DA 2XUTA 3O7PA 2CFQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IU8 A;  4OH3 A;  4XNJ A;  4ZWC A;  4IKZ A;  5D58 A;  4ZYR A;  4UVM A;  4LEP A;  4U4V A;  4TPJ A;  4APS A;  4TPH A;  4GC0 A;  5A2O A;  3O7Q A;  4TPG A;  2CFP A;  4ZW9 A;  4IKX A;  1PV7 A;  5A2N A;  1PW4 A;  3WDO A;  4D2B A;  4U4W A;  4GBZ A;  4D2C A;  4QIQ A;  4IU9 A;  5EQH A;  5C65 A;  4J05 A;  4W6V A;  4YB9 D;  5EQI A;  2Y5Y A;  4PYP A;  4OAA A;  4U4T A;  4JR9 A;  4IKW A;  5D6K A;  4JA3 A;  4LDS A;  4GBY A;  4JRE A;  5D59 A;  1PV6 A;  4IKY A;  4Q65 A;  5EQG A;  2V8N A;  4ZWB A;  4XNI A;  5GXB A;  4YBQ A;  4IKV A;  4D2D A;  2XUT A;  3O7P A;  2CFQ A; 
#chains in the Genus database with same CATH topology
 1PY2 A;  2B8X A;  3HOW D;  3L5W I;  1V7N V;  2O26 A;  4GS7 A;  3NPZ A;  1ITM A;  3BPN A;  1RHG A;  3INK C;  4A3D D;  1GA3 A;  4YQX A;  4Z5R D;  4EXP A;  1BGD A;  1IK0 A;  4LRL A;  4U4V A;  4APS A;  4GC0 A;  1RFB A;  1INR A;  1PW4 A;  4IU9 A;  4PYP A;  4A3C D;  1BGE A;  3N0P A;  1ILK A;  2V8N A;  5D22 A;  3QB1 A;  5D58 A;  4GRW A;  4TPJ A;  1QVN A;  4A3J D;  3WCY I;  4YB9 D;  1PW6 A;  4MHL A;  1BGC A;  3FKI D;  1CSG A;  1HWG A;  1ITF A;  1EMR A;  3O7P A;  3PO2 D;  2B8U A;  2L3Y A;  4NEJ A;  4TPH A;  5A2O A;  1BBN A;  1PV7 A;  4ZF7 A;  1PGR A;  1HWH A;  5C65 A;  4J05 A;  5IYB D;  5IP9 D;  1M4R A;  4JR9 A;  1CYL A;  1WCM D;  2B8Z A;  2ERJ D;  2XUT A;  1AX8 A;  4A3I D;  2JA7 D;  2Q14 A;  2ILK A;  3HOY D;  4PS4 A;  4NN7 A;  3HOU D;  1Y6M L;  4D2C A;  2Y5Y A;  1Y1W D;  4IKW A;  5D6K A;  1Y1V D;  3L5X A;  1HIK A;  5D72 A;  5C44 D;  1YKB A;  1N1F A;  4XNI A;  4BBS D;  3WDO A;  1ETE A;  4ZWC A;  3PO3 D;  3OG6 A;  5IYD D;  2JA5 D;  2L3O A;  2D9Q A;  1I1R B;  2H24 A;  3AYH A;  3HOZ D;  2Q7N B;  4U4W A;  1LKI A;  2B91 A;  5IP7 D;  4BBR D;  1AU1 A;  1PV6 A;  1HUL A;  4IKY A;  1ALU A;  2B63 D;  4ZS7 A;  1CNT 1;  3D48 P;  3NCC A;  1BCN A;  1D9C A;  3PIV A;  1GNC A;  1EXZ A;  5FLM D;  4QIQ A;  3Q1S I;  1SCF A;  5KNH I;  3QAZ A;  1HUW A;  3UEZ E;  4RS1 A;  1M4B A;  2O27 A;  5C7X A;  2KZ1 A;  5D28 B;  5GXB A;  3NCE A;  4J4L C;  1Y14 A;  4NKQ C;  1EER A;  3O7Q A;  1HGU A;  4CNI C;  2JA6 D;  4EXN A;  1V7M V;  4DKD A;  3BES L;  1NBP A;  2O6I A;  3HHC A;  5L6Y C;  2CFQ A;  4XNJ A;  4NN5 A;  1A7M A;  3DI2 A;  3OG4 A;  2Z3Q A;  4TPG A;  2E9W C;  4DKE A;  2CFP A;  1Z92 A;  3UF5 A;  2IL6 A;  3EJJ A;  3TGX B;  1IAR A;  5EQH A;  2B90 A;  4OAA A;  4A93 D;  3MZG A;  1CN4 C;  2INT A;  1M48 A;  1M4A A;  2GMF A;  5IYC D;  4ZYR A;  4O9H A;  2R92 D;  4ZW9 A;  4YUE C;  5A2N A;  3H0G D;  2CYK A;  2Q98 A;  3HMX B;  4A3M D;  2B8Y A;  4O6K A;  1ITL A;  3NCB A;  1D9G A;  1Z7C A;  3D85 C;  4DOH A;  1WU3 I;  5EQG A;  1BUY A;  4YBQ A;  4IKV A;  1F45 B;  1FG9 A;  3VA2 A;  4X51 A;  4IKZ A;  1AXI A;  5LQB A;  3HOX D;  5D71 A;  4D2B A;  4BY1 D;  3I4M D;  4JA3 A;  1J7V L;  4JRE A;  2C35 A;  3N06 A;  2HYM B;  4ZWB A;  4YPG C;  1EKU A;  1FYH A;  3NCF A;  1BP3 A;  1KF9 A;  1Y6N L;  4LEP A;  2Z3R A;  3DI3 A;  3PIW A;  5FHX A;  5TS9 A;  3QT2 C;  3B5K A;  3H3V E;  1F6F A;  3OQ3 A;  4FA8 E;  5FUC A;  3G6D A;  1M4C A;  3I4N D;  3BPL A;  1RCB A;  3D87 A;  4NI9 A;  2JA8 D;  4IKX A;  4GBZ A;  3UF2 A;  4W6V A;  2XQB A;  5D70 A;  5EQI A;  3QB7 A;  4U4T A;  3BPO A;  4GBY A;  2LMS A;  3SE3 B;  4A3E D;  3S9D A;  2VUM D;  1PVH B;  4UVM A;  1IRL A;  2B5I A;  3DGC L;  3UX9 A;  4A3B D;  4A3L D;  1ITI A;  2R7Z D;  5C4X D;  1M49 A;  4YDY I;  3G9V B;  3EW3 A;  1P9M B;  1A22 A;  4I77 Z;  4NI7 A;  2PSM A;  5E4E A;  1RW5 A;  5D59 A;  3HHR A;  4D2D A;  1HIJ A;  5C3E D;  4IU8 A;  2OQP A;  2R93 D;  4DKF A;  1B5L A;  1CD9 A;  4WRL B;  1JLI A;  2LAG A;  1IL6 A;  4NEM A;  4LDS A;  4DKC A;  4BY7 D;  3LB6 A;  4Q65 A;  3SE4 B;  1LQS L;  4OH3 A;  1HZI A;  1IJZ A;  1VLK A;  4NN6 A;  4A3G D;  4A3K D;  3HOV D;  4BXX D;  3DUH C;  1Y6K L;  1EVS A;  3DLQ I;  3LB6 B;  4A3F D;  2D48 A;  3IRH A;  1M47 A;  1LK3 A;  3QWR B; 
#chains in the Genus database with same CATH homology
 4IU8 A;  4OH3 A;  4XNJ A;  4ZWC A;  4IKZ A;  5D58 A;  4ZYR A;  4UVM A;  4LEP A;  4U4V A;  4TPJ A;  4APS A;  4TPH A;  4GC0 A;  5A2O A;  3O7Q A;  4TPG A;  2CFP A;  4ZW9 A;  4IKX A;  1PV7 A;  5A2N A;  1PW4 A;  3WDO A;  4D2B A;  4U4W A;  4GBZ A;  4D2C A;  4QIQ A;  4IU9 A;  5EQH A;  5C65 A;  4J05 A;  4W6V A;  4YB9 D;  5EQI A;  2Y5Y A;  4PYP A;  4OAA A;  4U4T A;  4JR9 A;  4IKW A;  5D6K A;  4JA3 A;  4LDS A;  4GBY A;  4JRE A;  5D59 A;  1PV6 A;  4IKY A;  4Q65 A;  5EQG A;  2V8N A;  4ZWB A;  4XNI A;  5GXB A;  4YBQ A;  4IKV A;  4D2D A;  2XUT A;  3O7P A;  2CFQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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