4EXPA

Structure of mouse interleukin-34 in complex with mouse fms
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
171
structure length
171
Chain Sequence
WTLTQDKECDLTGYLRGKLQYKNRLQYMKHYFPINYRIAVPYEGVLRVANITRLQKAHVSERELRYLWVLVSLNATESVMDVLLEGHPSWKYLQEVQTLLENVQRSLMDVEIGPHVEAVLSLLSTPGLSLKLVRPKALLDNCFRVMELLYCSCCKQSPILKWQDCELPAAA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
pubmed doi rcsb
molecule tags Cytokine/transferase
source organism Mus musculus
molecule keywords Interleukin-34
total genus 57
structure length 171
sequence length 171
ec nomenclature
pdb deposition date 2012-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF15036 IL34 Interleukin 34
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.80 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4expA00
4DKEA 4DKDA 4DKCA 4EXPA 4DKFA 4EXNA
chains in the Genus database with same CATH superfamily
5D22A 4IKYA 2JA5D 1D9CA 4NN6A 2XUTA 1BGEA 1GNCA 4APSA 4TPHA 3NPZA 1M4CA 1RFBA 2B8UA 2H24A 3HOYD 2CYKA 4A3GD 3AYHA 1ITLA 5D72A 1WCMD 5FLMD 3H3VE 3OQ3A 4EXNA 2V8NA 1EKUA 4ZF7A 4A3ID 2O6IA 1Y6NL 4ZS7A 2O26A 3EW3A 1PV6A 3UF2A 3QAZA 2R92D 2LMSA 4YQXA 2INTA 3TGXB 3L5XA 4O6KA 3DI2A 1RHGA 3IRHA 2LAGA 4OH3A 4IKVA 2B90A 4GS7A 3L5WI 4A3LD 4NI7A 1CD9A 3HHCA 1HGUA 1EXZA 4NI9A 4OAAA 1Y1VD 4LRLA 4D2CA 3UEZE 4BY1D 1M48A 1BBNA 4IKZA 2Q14A 2JA6D 4GC0A 3HOXD 3DGCL 1D9GA 3LB6B 5C4XD 3B5KA 1FYHA 5FUCA 5KNHI 1ITFA 3PIVA 4LEPA 3QB1A 1CSGA 4BXXD 3LB6A 2C35A 4D2BA 5A2NA 1AU1A 5IYDD 1V7MV 4W6VA 4A3MD 2L3YA 1BP3A 4RS1A 4X51A 1J7VL 3I4MD 2B8XA 3INKC 4FA8E 5D6KA 5A2OA 1HZIA 4NEJA 1BGCA 5D28B 4ZW9A 4NN5A 4PYPA 3UF5A 1BUYA 2KZ1A 1HWGA 2B5IA 1BGDA 4A3BD 4I77Z 2B63D 3BPLA 3OG4A 2R7ZD 4ZWBA 1EMRA 5LQBA 2L3OA 5L6YC 1VLKA 1HULA 4JR9A 2R93D 3FKID 1KF9A 5D71A 2O27A 3NCFA 3WCYI 3EJJA 1HUWA 4IKXA 4EXPA 1ETEA 1EVSA 4A3DD 3H0GD 2OQPA 3DLQI 4JA3A 2Q7NB 4DOHA 3PIWA 1IL6A 2D48A 2XQBA 1M4BA 2B91A 4IU8A 1V7NV 1GA3A 4U4WA 5EQGA 3UX9A 5TS9A 1WU3I 3HMXB 3O7QA 1CNT1 1PVHB 1IJZA 1SCFA 4GBZA 4ZYRA 3PO2D 1I1RB 4J05A 1RW5A 3OG6A 4D2DA 3D85C 5EQHA 2JA8D 1LK3A 1PGRA 5C3ED 5IP7D 4A3JD 2Q98A 3O7PA 1AX8A 3NCEA 3WDOA 1HWHA 1IARA 4NN7A 5E4EA 4UVMA 5IYCD 3BESL 1IK0A 3D48P 1INRA 1PW4A 3HHRA 5D58A 5GXBA 3HOUD 1M4AA 4DKFA 4A93D 5C44D 4BBSD 4BY7D 1M4RA 1LQSL 4J4LC 1Y6ML 1IRLA 1QVNA 1F6FA 1LKIA 1A22A 3G9VB 2GMFA 4Z5RD 2Y5YA 4IKWA 1F45B 4A3ED 1BCNA 3S9DA 3N0PA 1ITIA 2E9WC 5IP9D 1A7MA 1HIKA 3DUHC 4TPJA 3NCCA 4ZWCA 4DKEA 4A3KD 1AXIA 5D70A 4U4TA 4YB9D 1CN4C 1P9MB 1ITMA 3D87A 3MZGA 1ALUA 4BBRD 2CFPA 3G6DA 3BPOA 4GBYA 3QWRB 1HIJA 1N1FA 4GRWA 4TPGA 3HOWD 4PS4A 3SE4B 4NEMA 3VA2A 1ILKA 1Z92A 1CYLA 1JLIA 2CFQA 2Z3QA 5IYBD 4JREA 3N06A 2B8YA 3DI3A 1PY2A 5EQIA 4WRLB 2HYMB 1PV7A 3Q1SI 4YDYI 1Y14A 2ILKA 3BPNA 4A3FD 1Z7CA 5D59A 4XNJA 5C65A 4LDSA 3SE3B 4O9HA 3HOVD 4NKQC 4U4VA 4YPGC 4IU9A 2ERJD 4YUEC 1B5LA 2Z3RA 1RCBA 1Y6KL 4MHLA 1FG9A 4XNIA 3I4ND 2JA7D 3HOZD 2D9QA 5FHXA 1M47A 3QT2C 4YBQA 1M49A 1Y1WD 2IL6A 2VUMD 1YKBA 3NCBA 5C7XA 1NBPA 4DKDA 1PW6A 3PO3D 4DKCA 4QIQA 4A3CD 1EERA 4Q65A 3QB7A 2PSMA 4CNIC 2B8ZA
chains in the Genus database with same CATH topology
1N1FA 1FYHA 5FUCA 5D22A 5KNHI 1ITFA 3PIVA 1CNT1 3HMXB 3QB1A 1PVHB 1CSGA 4GRWA 4BXXD 3LB6A 1IJZA 1SCFA 2JA5D 1D9CA 1BCNA 2C35A 3HOWD 4PS4A 3SE4B 4CNIC 4NEMA 4NN6A 3PO2D 1AU1A 3VA2A 1ILKA 1Z92A 5IYDD 1I1RB 1BGEA 1CYLA 1GNCA 1V7MV 3NPZA 1JLIA 1M4CA 1RFBA 1RW5A 3OG6A 2B8UA 4A3MD 2L3YA 1BP3A 2H24A 2Z3QA 2CYKA 4RS1A 3HOYD 3D85C 2JA8D 4X51A 4A3GD 3AYHA 1ITLA 1J7VL 5D72A 5IYBD 1WCMD 3I4MD 2B8XA 3INKC 1LK3A 1PGRA 5FLMD 4FA8E 3N06A 3H3VE 5C3ED 2B8YA 3OQ3A 3DI3A 1PY2A 5IP7D 4EXNA 1HZIA 4NEJA 4WRLB 4A3JD 2HYMB 1BGCA 5D28B 2Q98A 1AX8A 3NCEA 3Q1SI 4YDYI 1EKUA 1HWHA 1Y14A 4ZF7A 1IARA 4A3ID 4NN5A 4NN7A 5E4EA 2O6IA 1Y6NL 2ILKA 5IYCD 4ZS7A 2O26A 3BESL 3EW3A 3UF2A 3QAZA 3UF5A 2R92D 1BUYA 3D48P 1INRA 3BPNA 2LMSA 4YQXA 1IK0A 4A3FD 2KZ1A 1Z7CA 2INTA 3TGXB 1HWGA 2B5IA 1BGDA 3L5XA 3HOUD 4A3BD 1M4AA 4I77Z 2B63D 4DKFA 4A93D 5C44D 3BPLA 4BBSD 3OG4A 3SE3B 4BY7D 4O9HA 1M4RA 2R7ZD 3HOVD 4O6KA 3DI2A 1LQSL 1RHGA 4NKQC 1EMRA 4YPGC 3IRHA 2LAGA 5LQBA 2B90A 2ERJD 2L3OA 5L6YC 1VLKA 1HULA 4J4LC 4GS7A 1Y6ML 4YUEC 2R93D 1IRLA 3FKID 4A3LD 1QVNA 1F6FA 1KF9A 1LKIA 1A22A 3L5WI 5D71A 4NI7A 1CD9A 3HHCA 3G9VB 2GMFA 2O27A 4Z5RD 3NCFA 3WCYI 1B5LA 3EJJA 1F45B 1HUWA 4A3ED 2Z3RA 1RCBA 1HGUA 1EXZA 4EXPA 3S9DA 4NI9A 1ETEA 1EVSA 3N0PA 1Y6KL 1ITIA 4A3DD 1Y1VD 2E9WC 4LRLA 4MHLA 3UEZE 3H0GD 5IP9D 1FG9A 4BY1D 1M48A 1A7MA 3I4ND 1BBNA 1HIKA 2OQPA 3DLQI 2Q14A 3DUHC 2JA6D 2JA7D 2Q7NB 3HOZD 2D9QA 3NCCA 5FHXA 1M47A 4DKEA 4DOHA 3HOXD 3QT2C 1Y1WD 1M49A 3PIWA 2IL6A 4A3KD 2VUMD 1YKBA 1AXIA 1IL6A 2D48A 3NCBA 5D70A 3DGCL 1NBPA 5C7XA 4DKDA 1CN4C 1P9MB 1PW6A 1ITMA 3D87A 2XQBA 3MZGA 3PO3D 1D9GA 1ALUA 3LB6B 4DKCA 1M4BA 4A3CD 2B91A 1EERA 4BBRD 1V7NV 3G6DA 1GA3A 3BPOA 5C4XD 3B5KA 3QB7A 3QWRB 1HIJA 3UX9A 5TS9A 1WU3I 2PSMA 3HHRA 2B8ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DKE A;  4DKD A;  4DKC A;  4EXP A;  4DKF A;  4EXN A; 
#chains in the Genus database with same CATH topology
 5D22 A;  4IKY A;  2JA5 D;  1D9C A;  4NN6 A;  2XUT A;  1BGE A;  1GNC A;  4APS A;  4TPH A;  3NPZ A;  1M4C A;  1RFB A;  2B8U A;  2H24 A;  3HOY D;  2CYK A;  4A3G D;  3AYH A;  1ITL A;  5D72 A;  1WCM D;  5FLM D;  3H3V E;  3OQ3 A;  4EXN A;  2V8N A;  1EKU A;  4ZF7 A;  4A3I D;  2O6I A;  1Y6N L;  4ZS7 A;  2O26 A;  3EW3 A;  1PV6 A;  3UF2 A;  3QAZ A;  2R92 D;  2LMS A;  4YQX A;  2INT A;  3TGX B;  3L5X A;  4O6K A;  3DI2 A;  1RHG A;  3IRH A;  2LAG A;  4OH3 A;  4IKV A;  2B90 A;  4GS7 A;  3L5W I;  4A3L D;  4NI7 A;  1CD9 A;  3HHC A;  1HGU A;  1EXZ A;  4NI9 A;  4OAA A;  1Y1V D;  4LRL A;  4D2C A;  3UEZ E;  4BY1 D;  1M48 A;  1BBN A;  4IKZ A;  2Q14 A;  2JA6 D;  4GC0 A;  3HOX D;  3DGC L;  1D9G A;  3LB6 B;  5C4X D;  3B5K A;  1FYH A;  5FUC A;  5KNH I;  1ITF A;  3PIV A;  4LEP A;  3QB1 A;  1CSG A;  4BXX D;  3LB6 A;  2C35 A;  4D2B A;  5A2N A;  1AU1 A;  5IYD D;  1V7M V;  4W6V A;  4A3M D;  2L3Y A;  1BP3 A;  4RS1 A;  4X51 A;  1J7V L;  3I4M D;  2B8X A;  3INK C;  4FA8 E;  5D6K A;  5A2O A;  1HZI A;  4NEJ A;  1BGC A;  5D28 B;  4ZW9 A;  4NN5 A;  4PYP A;  3UF5 A;  1BUY A;  2KZ1 A;  1HWG A;  2B5I A;  1BGD A;  4A3B D;  4I77 Z;  2B63 D;  3BPL A;  3OG4 A;  2R7Z D;  4ZWB A;  1EMR A;  5LQB A;  2L3O A;  5L6Y C;  1VLK A;  1HUL A;  4JR9 A;  2R93 D;  3FKI D;  1KF9 A;  5D71 A;  2O27 A;  3NCF A;  3WCY I;  3EJJ A;  1HUW A;  4IKX A;  4EXP A;  1ETE A;  1EVS A;  4A3D D;  3H0G D;  2OQP A;  3DLQ I;  4JA3 A;  2Q7N B;  4DOH A;  3PIW A;  1IL6 A;  2D48 A;  2XQB A;  1M4B A;  2B91 A;  4IU8 A;  1V7N V;  1GA3 A;  4U4W A;  5EQG A;  3UX9 A;  5TS9 A;  1WU3 I;  3HMX B;  3O7Q A;  1CNT 1;  1PVH B;  1IJZ A;  1SCF A;  4GBZ A;  4ZYR A;  3PO2 D;  1I1R B;  4J05 A;  1RW5 A;  3OG6 A;  4D2D A;  3D85 C;  5EQH A;  2JA8 D;  1LK3 A;  1PGR A;  5C3E D;  5IP7 D;  4A3J D;  2Q98 A;  3O7P A;  1AX8 A;  3NCE A;  3WDO A;  1HWH A;  1IAR A;  4NN7 A;  5E4E A;  4UVM A;  5IYC D;  3BES L;  1IK0 A;  3D48 P;  1INR A;  1PW4 A;  3HHR A;  5D58 A;  5GXB A;  3HOU D;  1M4A A;  4DKF A;  4A93 D;  5C44 D;  4BBS D;  4BY7 D;  1M4R A;  1LQS L;  4J4L C;  1Y6M L;  1IRL A;  1QVN A;  1F6F A;  1LKI A;  1A22 A;  3G9V B;  2GMF A;  4Z5R D;  2Y5Y A;  4IKW A;  1F45 B;  4A3E D;  1BCN A;  3S9D A;  3N0P A;  1ITI A;  2E9W C;  5IP9 D;  1A7M A;  1HIK A;  3DUH C;  4TPJ A;  3NCC A;  4ZWC A;  4DKE A;  4A3K D;  1AXI A;  5D70 A;  4U4T A;  4YB9 D;  1CN4 C;  1P9M B;  1ITM A;  3D87 A;  3MZG A;  1ALU A;  4BBR D;  2CFP A;  3G6D A;  3BPO A;  4GBY A;  3QWR B;  1HIJ A;  1N1F A;  4GRW A;  4TPG A;  3HOW D;  4PS4 A;  3SE4 B;  4NEM A;  3VA2 A;  1ILK A;  1Z92 A;  1CYL A;  1JLI A;  2CFQ A;  2Z3Q A;  5IYB D;  4JRE A;  3N06 A;  2B8Y A;  3DI3 A;  1PY2 A;  5EQI A;  4WRL B;  2HYM B;  1PV7 A;  3Q1S I;  4YDY I;  1Y14 A;  2ILK A;  3BPN A;  4A3F D;  1Z7C A;  5D59 A;  4XNJ A;  5C65 A;  4LDS A;  3SE3 B;  4O9H A;  3HOV D;  4NKQ C;  4U4V A;  4YPG C;  4IU9 A;  2ERJ D;  4YUE C;  1B5L A;  2Z3R A;  1RCB A;  1Y6K L;  4MHL A;  1FG9 A;  4XNI A;  3I4N D;  2JA7 D;  3HOZ D;  2D9Q A;  5FHX A;  1M47 A;  3QT2 C;  4YBQ A;  1M49 A;  1Y1W D;  2IL6 A;  2VUM D;  1YKB A;  3NCB A;  5C7X A;  1NBP A;  4DKD A;  1PW6 A;  3PO3 D;  4DKC A;  4QIQ A;  4A3C D;  1EER A;  4Q65 A;  3QB7 A;  2PSM A;  4CNI C;  2B8Z A; 
#chains in the Genus database with same CATH homology
 1N1F A;  1FYH A;  5FUC A;  5D22 A;  5KNH I;  1ITF A;  3PIV A;  1CNT 1;  3HMX B;  3QB1 A;  1PVH B;  1CSG A;  4GRW A;  4BXX D;  3LB6 A;  1IJZ A;  1SCF A;  2JA5 D;  1D9C A;  1BCN A;  2C35 A;  3HOW D;  4PS4 A;  3SE4 B;  4CNI C;  4NEM A;  4NN6 A;  3PO2 D;  1AU1 A;  3VA2 A;  1ILK A;  1Z92 A;  5IYD D;  1I1R B;  1BGE A;  1CYL A;  1GNC A;  1V7M V;  3NPZ A;  1JLI A;  1M4C A;  1RFB A;  1RW5 A;  3OG6 A;  2B8U A;  4A3M D;  2L3Y A;  1BP3 A;  2H24 A;  2Z3Q A;  2CYK A;  4RS1 A;  3HOY D;  3D85 C;  2JA8 D;  4X51 A;  4A3G D;  3AYH A;  1ITL A;  1J7V L;  5D72 A;  5IYB D;  1WCM D;  3I4M D;  2B8X A;  3INK C;  1LK3 A;  1PGR A;  5FLM D;  4FA8 E;  3N06 A;  3H3V E;  5C3E D;  2B8Y A;  3OQ3 A;  3DI3 A;  1PY2 A;  5IP7 D;  4EXN A;  1HZI A;  4NEJ A;  4WRL B;  4A3J D;  2HYM B;  1BGC A;  5D28 B;  2Q98 A;  1AX8 A;  3NCE A;  3Q1S I;  4YDY I;  1EKU A;  1HWH A;  1Y14 A;  4ZF7 A;  1IAR A;  4A3I D;  4NN5 A;  4NN7 A;  5E4E A;  2O6I A;  1Y6N L;  2ILK A;  5IYC D;  4ZS7 A;  2O26 A;  3BES L;  3EW3 A;  3UF2 A;  3QAZ A;  3UF5 A;  2R92 D;  1BUY A;  3D48 P;  1INR A;  3BPN A;  2LMS A;  4YQX A;  1IK0 A;  4A3F D;  2KZ1 A;  1Z7C A;  2INT A;  3TGX B;  1HWG A;  2B5I A;  1BGD A;  3L5X A;  3HOU D;  4A3B D;  1M4A A;  4I77 Z;  2B63 D;  4DKF A;  4A93 D;  5C44 D;  3BPL A;  4BBS D;  3OG4 A;  3SE3 B;  4BY7 D;  4O9H A;  1M4R A;  2R7Z D;  3HOV D;  4O6K A;  3DI2 A;  1LQS L;  1RHG A;  4NKQ C;  1EMR A;  4YPG C;  3IRH A;  2LAG A;  5LQB A;  2B90 A;  2ERJ D;  2L3O A;  5L6Y C;  1VLK A;  1HUL A;  4J4L C;  4GS7 A;  1Y6M L;  4YUE C;  2R93 D;  1IRL A;  3FKI D;  4A3L D;  1QVN A;  1F6F A;  1KF9 A;  1LKI A;  1A22 A;  3L5W I;  5D71 A;  4NI7 A;  1CD9 A;  3HHC A;  3G9V B;  2GMF A;  2O27 A;  4Z5R D;  3NCF A;  3WCY I;  1B5L A;  3EJJ A;  1F45 B;  1HUW A;  4A3E D;  2Z3R A;  1RCB A;  1HGU A;  1EXZ A;  4EXP A;  3S9D A;  4NI9 A;  1ETE A;  1EVS A;  3N0P A;  1Y6K L;  1ITI A;  4A3D D;  1Y1V D;  2E9W C;  4LRL A;  4MHL A;  3UEZ E;  3H0G D;  5IP9 D;  1FG9 A;  4BY1 D;  1M48 A;  1A7M A;  3I4N D;  1BBN A;  1HIK A;  2OQP A;  3DLQ I;  2Q14 A;  3DUH C;  2JA6 D;  2JA7 D;  2Q7N B;  3HOZ D;  2D9Q A;  3NCC A;  5FHX A;  1M47 A;  4DKE A;  4DOH A;  3HOX D;  3QT2 C;  1Y1W D;  1M49 A;  3PIW A;  2IL6 A;  4A3K D;  2VUM D;  1YKB A;  1AXI A;  1IL6 A;  2D48 A;  3NCB A;  5D70 A;  3DGC L;  1NBP A;  5C7X A;  4DKD A;  1CN4 C;  1P9M B;  1PW6 A;  1ITM A;  3D87 A;  2XQB A;  3MZG A;  3PO3 D;  1D9G A;  1ALU A;  3LB6 B;  4DKC A;  1M4B A;  4A3C D;  2B91 A;  1EER A;  4BBR D;  1V7N V;  3G6D A;  1GA3 A;  3BPO A;  5C4X D;  3B5K A;  3QB7 A;  3QWR B;  1HIJ A;  3UX9 A;  5TS9 A;  1WU3 I;  2PSM A;  3HHR A;  2B8Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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