4GBZA

The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-glucose
Total Genus 198
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
198
sequence length
475
structure length
475
Chain Sequence
YNSSYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVAPQNLSESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGSAWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIRGKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLMSRGKQEQAEGILRKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVGVIVIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCWVLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETKGKTLEELEALWE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a bacterial homologue of glucose transporters GLUT1-4.
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli
molecule keywords D-xylose-proton symporter
total genus 198
structure length 475
sequence length 475
ec nomenclature
pdb deposition date 2012-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4gbzA01
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4gbzA02
4JREA 4GC0A 4XNJA 4ZYRA 2CFQA 4D2BA 4OAAA 2CFPA 4TPHA 4IKXA 5EQIA 5GXBA 2Y5YA 4IKVA 4UVMA 4IKWA 5C65A 5EQGA 4U4WA 5EQHA 4LDSA 5D58A 3O7PA 4APSA 4W6VA 4ZWCA 4GBZA 4U4TA 5D59A 4PYPA 4QIQA 3WDOA 4IU9A 4U4VA 4TPJA 1PV7A 5D6KA 1PW4A 4IKYA 4IKZA 4TPGA 4XNIA 3O7QA 4ZW9A 4Q65A 4GBYA 4IU8A 4OH3A 5A2NA 5A2OA 2V8NA 4D2DA 2XUTA 4JA3A 4LEPA 4ZWBA 4YBQA 4YB9D 1PV6A 4JR9A 4D2CA 4J05A
chains in the Genus database with same CATH superfamily
1BGCA 5D71A 4TPHA 3O7PA 5D22A 2H24A 2ERJD 4ZF7A 1HZIA 1GA3A 1PW6A 2Q7NB 2L3YA 1ITLA 3I4MD 3QB1A 4LDSA 3BPNA 4JREA 1ILKA 1CYLA 1LK3A 3SE4B 2R7ZD 1CSGA 3OG4A 2B90A 2Q14A 1AXIA 4A3ID 4GBYA 5IYDD 3LB6B 1Z92A 1KF9A 3QWRB 2V8NA 4A3CD 1EMRA 1HIJA 4JA3A 4YBQA 2O6IA 1PV6A 4JR9A 1M47A 4D2DA 5D6KA 5C3ED 5C7XA 2O27A 4UVMA 4RS1A 1A22A 1F6FA 4BY7D 3WDOA 5E4EA 3PO2D 1AU1A 3NCBA 4A3KD 4BBSD 4X51A 4YQXA 2IL6A 2XUTA 5IP9D 3NCCA 1ITIA 1V7NV 1EERA 3N06A 1M48A 4IKXA 4A93D 4ZS7A 3FKID 4IU9A 4U4VA 4YUEC 3HOXD 2HYMB 4EXPA 2Z3QA 1Y14A 3IRHA 5TS9A 4O6KA 1D9CA 4YB9D 4NEMA 2LMSA 2CYKA 2B8ZA 4MHLA 4BXXD 4EXNA 1M4RA 4IKWA 1M4BA 5EQGA 5EQHA 3HHCA 3G9VB 5IYCD 1Y6ML 2INTA 1BBNA 1HWGA 4IU8A 4A3JD 2B91A 4NN5A 5IP7D 1WU3I 3DI3A 5FHXA 4NI7A 2E9WC 4ZYRA 2B8UA 4CNIC 4A3LD 1BGEA 4IKVA 4A3DD 1PVHB 3PIWA 3UEZE 5D58A 4APSA 3OG6A 1HGUA 1EKUA 4TPJA 3HOYD 4XNIA 1HIKA 5LQBA 4LRLA 4WRLB 3UF5A 1INRA 2R92D 1AX8A 3H0GD 2CFQA 4PS4A 3DUHC 1RW5A 3PIVA 4NI9A 4IKYA 2KZ1A 1ITFA 2Z3RA 1B5LA 4ZWBA 1BUYA 1WCMD 3QAZA 2Q98A 2CFPA 2B8XA 5C4XD 5EQIA 2JA5D 2PSMA 3D87A 4BBRD 1Y1WD 1NBPA 1RHGA 4ZW9A 1BGDA 5A2OA 3D85C 1IJZA 3NPZA 2L3OA 2C35A 1LKIA 1ALUA 3SE3B 1M4AA 3N0PA 3QT2C 3INKC 5D59A 5D72A 2O26A 5FUCA 2D48A 1M4CA 3HHRA 1CNT1 3TGXB 1SCFA 3BPOA 5D70A 4NN7A 1EVSA 1HULA 3DGCL 5FLMD 4D2CA 3HOZD 4GRWA 3L5XA 2JA7D 1Y1VD 5C65A 5IYBD 3H3VE 3QB7A 1RFBA 1QVNA 2R93D 1PW4A 4NN6A 2B5IA 1HWHA 4Z5RD 3MZGA 4XNJA 3HOUD 4DKFA 5L6YC 1ITMA 1I1RB 1FG9A 4PYPA 1A7MA 3O7QA 3UF2A 4GC0A 1BCNA 4NKQC 4FA8E 3PO3D 2GMFA 3EJJA 1J7VL 1V7MV 3S9DA 4W6VA 3G6DA 4QIQA 1PY2A 2D9QA 4Q65A 1Y6KL 2VUMD 3BPLA 4BY1D 4YDYI 1IK0A 1F45B 1Z7CA 4A3MD 1Y6NL 4D2BA 1M49A 3I4ND 4ZWCA 4GBZA 4U4TA 4NEJA 2LAGA 4I77Z 4DKEA 5A2NA 1CN4C 1FYHA 4LEPA 5D28B 1LQSL 3HOVD 3WCYI 5GXBA 5C44D 1CD9A 4U4WA 3BESL 1ETEA 1JLIA 3Q1SI 5KNHI 4TPGA 3L5WI 1IARA 3HMXB 4OH3A 3EW3A 2B63D 1EXZA 1BP3A 1RCBA 3D48P 4DKDA 1PGRA 1YKBA 3HOWD 4J05A 3VA2A 4DKCA 1N1FA 3AYHA 4J4LC 2Y5YA 3B5KA 2JA8D 3DLQI 4A3GD 1IL6A 4A3ED 4YPGC 4DOHA 1HUWA 2B8YA 2JA6D 2OQPA 2XQBA 1D9GA 4OAAA 1GNCA 3DI2A 3OQ3A 3NCFA 4A3BD 4O9HA 4GS7A 1PV7A 1VLKA 4IKZA 3UX9A 1P9MB 3NCEA 1IRLA 4A3FD 2ILKA 3LB6A
chains in the Genus database with same CATH topology
4JREA 4GC0A 4XNJA 4ZYRA 2CFQA 4D2BA 4OAAA 2CFPA 4TPHA 4IKXA 5EQIA 5GXBA 2Y5YA 4IKVA 4UVMA 4IKWA 5C65A 5EQGA 4U4WA 5EQHA 4LDSA 5D58A 3O7PA 4APSA 4W6VA 4ZWCA 4GBZA 4U4TA 5D59A 4PYPA 4QIQA 3WDOA 4IU9A 4U4VA 4TPJA 1PV7A 5D6KA 1PW4A 4IKYA 4IKZA 4TPGA 4XNIA 3O7QA 4ZW9A 4Q65A 4GBYA 4IU8A 4OH3A 5A2NA 5A2OA 2V8NA 4D2DA 2XUTA 4JA3A 4LEPA 4ZWBA 4YBQA 4YB9D 1PV6A 4JR9A 4D2CA 4J05A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JRE A;  4GC0 A;  4XNJ A;  4ZYR A;  2CFQ A;  4D2B A;  4OAA A;  2CFP A;  4TPH A;  4IKX A;  5EQI A;  5GXB A;  2Y5Y A;  4IKV A;  4UVM A;  4IKW A;  5C65 A;  5EQG A;  4U4W A;  5EQH A;  4LDS A;  5D58 A;  3O7P A;  4APS A;  4W6V A;  4ZWC A;  4GBZ A;  4U4T A;  5D59 A;  4PYP A;  4QIQ A;  3WDO A;  4IU9 A;  4U4V A;  4TPJ A;  1PV7 A;  5D6K A;  1PW4 A;  4IKY A;  4IKZ A;  4TPG A;  4XNI A;  3O7Q A;  4ZW9 A;  4Q65 A;  4GBY A;  4IU8 A;  4OH3 A;  5A2N A;  5A2O A;  2V8N A;  4D2D A;  2XUT A;  4JA3 A;  4LEP A;  4ZWB A;  4YBQ A;  4YB9 D;  1PV6 A;  4JR9 A;  4D2C A;  4J05 A; 
#chains in the Genus database with same CATH topology
 1BGC A;  5D71 A;  4TPH A;  3O7P A;  5D22 A;  2H24 A;  2ERJ D;  4ZF7 A;  1HZI A;  1GA3 A;  1PW6 A;  2Q7N B;  2L3Y A;  1ITL A;  3I4M D;  3QB1 A;  4LDS A;  3BPN A;  4JRE A;  1ILK A;  1CYL A;  1LK3 A;  3SE4 B;  2R7Z D;  1CSG A;  3OG4 A;  2B90 A;  2Q14 A;  1AXI A;  4A3I D;  4GBY A;  5IYD D;  3LB6 B;  1Z92 A;  1KF9 A;  3QWR B;  2V8N A;  4A3C D;  1EMR A;  1HIJ A;  4JA3 A;  4YBQ A;  2O6I A;  1PV6 A;  4JR9 A;  1M47 A;  4D2D A;  5D6K A;  5C3E D;  5C7X A;  2O27 A;  4UVM A;  4RS1 A;  1A22 A;  1F6F A;  4BY7 D;  3WDO A;  5E4E A;  3PO2 D;  1AU1 A;  3NCB A;  4A3K D;  4BBS D;  4X51 A;  4YQX A;  2IL6 A;  2XUT A;  5IP9 D;  3NCC A;  1ITI A;  1V7N V;  1EER A;  3N06 A;  1M48 A;  4IKX A;  4A93 D;  4ZS7 A;  3FKI D;  4IU9 A;  4U4V A;  4YUE C;  3HOX D;  2HYM B;  4EXP A;  2Z3Q A;  1Y14 A;  3IRH A;  5TS9 A;  4O6K A;  1D9C A;  4YB9 D;  4NEM A;  2LMS A;  2CYK A;  2B8Z A;  4MHL A;  4BXX D;  4EXN A;  1M4R A;  4IKW A;  1M4B A;  5EQG A;  5EQH A;  3HHC A;  3G9V B;  5IYC D;  1Y6M L;  2INT A;  1BBN A;  1HWG A;  4IU8 A;  4A3J D;  2B91 A;  4NN5 A;  5IP7 D;  1WU3 I;  3DI3 A;  5FHX A;  4NI7 A;  2E9W C;  4ZYR A;  2B8U A;  4CNI C;  4A3L D;  1BGE A;  4IKV A;  4A3D D;  1PVH B;  3PIW A;  3UEZ E;  5D58 A;  4APS A;  3OG6 A;  1HGU A;  1EKU A;  4TPJ A;  3HOY D;  4XNI A;  1HIK A;  5LQB A;  4LRL A;  4WRL B;  3UF5 A;  1INR A;  2R92 D;  1AX8 A;  3H0G D;  2CFQ A;  4PS4 A;  3DUH C;  1RW5 A;  3PIV A;  4NI9 A;  4IKY A;  2KZ1 A;  1ITF A;  2Z3R A;  1B5L A;  4ZWB A;  1BUY A;  1WCM D;  3QAZ A;  2Q98 A;  2CFP A;  2B8X A;  5C4X D;  5EQI A;  2JA5 D;  2PSM A;  3D87 A;  4BBR D;  1Y1W D;  1NBP A;  1RHG A;  4ZW9 A;  1BGD A;  5A2O A;  3D85 C;  1IJZ A;  3NPZ A;  2L3O A;  2C35 A;  1LKI A;  1ALU A;  3SE3 B;  1M4A A;  3N0P A;  3QT2 C;  3INK C;  5D59 A;  5D72 A;  2O26 A;  5FUC A;  2D48 A;  1M4C A;  3HHR A;  1CNT 1;  3TGX B;  1SCF A;  3BPO A;  5D70 A;  4NN7 A;  1EVS A;  1HUL A;  3DGC L;  5FLM D;  4D2C A;  3HOZ D;  4GRW A;  3L5X A;  2JA7 D;  1Y1V D;  5C65 A;  5IYB D;  3H3V E;  3QB7 A;  1RFB A;  1QVN A;  2R93 D;  1PW4 A;  4NN6 A;  2B5I A;  1HWH A;  4Z5R D;  3MZG A;  4XNJ A;  3HOU D;  4DKF A;  5L6Y C;  1ITM A;  1I1R B;  1FG9 A;  4PYP A;  1A7M A;  3O7Q A;  3UF2 A;  4GC0 A;  1BCN A;  4NKQ C;  4FA8 E;  3PO3 D;  2GMF A;  3EJJ A;  1J7V L;  1V7M V;  3S9D A;  4W6V A;  3G6D A;  4QIQ A;  1PY2 A;  2D9Q A;  4Q65 A;  1Y6K L;  2VUM D;  3BPL A;  4BY1 D;  4YDY I;  1IK0 A;  1F45 B;  1Z7C A;  4A3M D;  1Y6N L;  4D2B A;  1M49 A;  3I4N D;  4ZWC A;  4GBZ A;  4U4T A;  4NEJ A;  2LAG A;  4I77 Z;  4DKE A;  5A2N A;  1CN4 C;  1FYH A;  4LEP A;  5D28 B;  1LQS L;  3HOV D;  3WCY I;  5GXB A;  5C44 D;  1CD9 A;  4U4W A;  3BES L;  1ETE A;  1JLI A;  3Q1S I;  5KNH I;  4TPG A;  3L5W I;  1IAR A;  3HMX B;  4OH3 A;  3EW3 A;  2B63 D;  1EXZ A;  1BP3 A;  1RCB A;  3D48 P;  4DKD A;  1PGR A;  1YKB A;  3HOW D;  4J05 A;  3VA2 A;  4DKC A;  1N1F A;  3AYH A;  4J4L C;  2Y5Y A;  3B5K A;  2JA8 D;  3DLQ I;  4A3G D;  1IL6 A;  4A3E D;  4YPG C;  4DOH A;  1HUW A;  2B8Y A;  2JA6 D;  2OQP A;  2XQB A;  1D9G A;  4OAA A;  1GNC A;  3DI2 A;  3OQ3 A;  3NCF A;  4A3B D;  4O9H A;  4GS7 A;  1PV7 A;  1VLK A;  4IKZ A;  3UX9 A;  1P9M B;  3NCE A;  1IRL A;  4A3F D;  2ILK A;  3LB6 A; 
#chains in the Genus database with same CATH homology
 4JRE A;  4GC0 A;  4XNJ A;  4ZYR A;  2CFQ A;  4D2B A;  4OAA A;  2CFP A;  4TPH A;  4IKX A;  5EQI A;  5GXB A;  2Y5Y A;  4IKV A;  4UVM A;  4IKW A;  5C65 A;  5EQG A;  4U4W A;  5EQH A;  4LDS A;  5D58 A;  3O7P A;  4APS A;  4W6V A;  4ZWC A;  4GBZ A;  4U4T A;  5D59 A;  4PYP A;  4QIQ A;  3WDO A;  4IU9 A;  4U4V A;  4TPJ A;  1PV7 A;  5D6K A;  1PW4 A;  4IKY A;  4IKZ A;  4TPG A;  4XNI A;  3O7Q A;  4ZW9 A;  4Q65 A;  4GBY A;  4IU8 A;  4OH3 A;  5A2N A;  5A2O A;  2V8N A;  4D2D A;  2XUT A;  4JA3 A;  4LEP A;  4ZWB A;  4YBQ A;  4YB9 D;  1PV6 A;  4JR9 A;  4D2C A;  4J05 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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