4NN5A

Cytokine receptor complex - crystal form 1a
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
121
structure length
109
Chain Sequence
YNFSNCNFTSITKIYCNIIFHDLTGDLKGAKFEQIEDCESKPACLLKIEYYTLNPIPGCPSLPDKTFARRTREALNDHCPGYPQEVQNICLQQTSQILRLWYSFMQSPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the proinflammatory signaling complex mediated by TSLP.
pubmed doi rcsb
molecule tags Cytokine/cytokine receptor
source organism Mus musculus
molecule keywords Thymic stromal lymphopoietin
total genus 45
structure length 109
sequence length 121
ec nomenclature
pdb deposition date 2013-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF15216 TSLP Thymic stromal lymphopoietin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.90 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4nn5A00
4NN6A 4NN5A 4NN7A
chains in the Genus database with same CATH superfamily
4YUEC 1GNCA 1PVHB 5D72A 4LDSA 4NI9A 2Q7NB 3EJJA 1HIKA 2B8XA 3OQ3A 2B5IA 1I1RB 1CYLA 3DI2A 5EQHA 5KNHI 5D70A 1INRA 3HHRA 1RW5A 3HOUD 1ILKA 1EERA 2R7ZD 4PS4A 3QT2C 4A3ED 3DI3A 4ZS7A 5D22A 3BPLA 2B63D 3OG4A 1RFBA 1J7VL 4YQXA 1IRLA 1Y14A 4GS7A 4O6KA 3NPZA 4Z5RD 4YBQA 3NCFA 1QVNA 1AXIA 3HHCA 5FUCA 4J05A 4IU9A 1EKUA 4BBRD 1IK0A 1RHGA 1HUWA 2O27A 5EQIA 4D2BA 4YDYI 1KF9A 2LMSA 3DGCL 5IYBD 4JA3A 1EXZA 1FYHA 1LQSL 5FHXA 4NN7A 1HWHA 4O9HA 3EW3A 3UF5A 2LAGA 1V7NV 1YKBA 4LRLA 3N06A 1D9GA 4DKFA 3SE4B 4DKCA 5A2OA 2O6IA 3LB6A 1M4AA 1M4CA 2IL6A 4U4WA 5C44D 1SCFA 4YB9D 4BY7D 1HULA 4MHLA 2B8UA 1WCMD 1BP3A 1RCBA 3NCBA 2CFPA 3D87A 4WRLB 3PO2D 4ZYRA 3NCEA 2D9QA 4GBZA 5IYCD 2CYKA 5A2NA 4FA8E 2B91A 1GA3A 1A22A 4J4LC 4ZWBA 4XNIA 3I4MD 3B5KA 4IKXA 1EMRA 1NBPA 3D85C 3O7PA 5TS9A 1D9CA 1ETEA 1HGUA 1BGDA 1PV7A 1M4BA 4NKQC 2HYMB 3PIVA 1B5LA 4JREA 3HMXB 4A3CD 2V8NA 4A3FD 4NN5A 4I77Z 4GBYA 2R92D 4A3ID 4NEJA 1AX8A 3MZGA 1JLIA 4GRWA 4X51A 4NN6A 4A93D 5IP9D 1LKIA 4IU8A 4IKYA 4APSA 4OH3A 3G9VB 2L3YA 3O7QA 2O26A 3UX9A 4A3MD 4TPHA 3WCYI 3HOYD 4Q65A 5IP7D 3OG6A 4A3JD 1A7MA 4A3BD 2KZ1A 1HZIA 1P9MB 3LB6B 3WDOA 5LQBA 4EXNA 2JA8D 2JA6D 1LK3A 4DKDA 1Z92A 3BPOA 1Y6ML 4OAAA 3AYHA 4A3GD 2OQPA 4D2CA 1PW4A 4LEPA 1HIJA 4BXXD 3NCCA 4PYPA 4RS1A 1ITMA 5IYDD 2Z3RA 1CD9A 1M4RA 1HWGA 4IKVA 2CFQA 4A3LD 3UEZE 3UF2A 3HOVD 5C3ED 3H0GD 3H3VE 4EXPA 3QB1A 1F45B 4DKEA 1PY2A 2C35A 3I4ND 4U4TA 2H24A 4IKZA 1AU1A 4ZWCA 3QB7A 1Y6NL 1CSGA 1ITIA 2PSMA 1PV6A 4CNIC 1N1FA 1BGEA 4XNJA 4DOHA 3DLQI 3IRHA 3BPNA 2GMFA 1M48A 4U4VA 3VA2A 4YPGC 3TGXB 3PIWA 2Q14A 1CN4C 4D2DA 1ITLA 3HOZD 1ALUA 5D58A 3HOXD 1ITFA 2D48A 3DUHC 4TPGA 5EQGA 4NEMA 4NI7A 4A3KD 2XQBA 1M49A 3FKID 3PO3D 1VLKA 4ZF7A 4ZW9A 2XUTA 4BBSD 4A3DD 2E9WC 1FG9A 2Z3QA 4JR9A 1CNT1 4GC0A 1V7MV 2JA7D 3L5XA 2Y5YA 1IARA 1WU3I 3QAZA 2ERJD 4IKWA 1BGCA 3N0PA 5E4EA 4TPJA 3Q1SI 1EVSA 5L6YC 4W6VA 5D71A 2R93D 1IL6A 5C65A 4UVMA 1PW6A 5GXBA 3HOWD 1F6FA 5C7XA 2Q98A 1Z7CA 3S9DA 5FLMD 3SE3B 3QWRB 3D48P 4BY1D 1M47A 2B90A 1Y6KL 2INTA 1BCNA 2ILKA 5D6KA 2VUMD 2B8YA 5C4XD 2JA5D 4QIQA 1PGRA 1BBNA 1Y1WD 1BUYA 5D59A 1Y1VD 1IJZA 2L3OA 3L5WI 3G6DA 2B8ZA 3INKC 3BESL 5D28B
chains in the Genus database with same CATH topology
4YUEC 1GNCA 1PVHB 3HOYD 5D72A 3UF5A 2LAGA 1ITLA 5IP7D 1V7NV 1YKBA 3OG6A 4NI9A 2Q7NB 3HOZD 1ALUA 4LRLA 4A3JD 3N06A 1A7MA 3EJJA 3HOXD 1D9GA 1HIKA 2B8XA 4A3BD 4DKFA 2KZ1A 1ITFA 2D48A 3SE4B 1HZIA 1P9MB 3OQ3A 3DUHC 3LB6B 4DKCA 5LQBA 4EXNA 2JA8D 2JA6D 2B5IA 1LK3A 2O6IA 4NEMA 4NI7A 3LB6A 4DKDA 4A3KD 1I1RB 1M4AA 1M4CA 1CYLA 3DI2A 2IL6A 1Z92A 2XQBA 5C44D 1M49A 1SCFA 3FKID 3PO3D 1VLKA 4BY7D 3BPOA 4ZF7A 1HULA 1Y6ML 4MHLA 3AYHA 2B8UA 4A3GD 2OQPA 5KNHI 1WCMD 1BP3A 1INRA 5D70A 1HIJA 1RCBA 3HHRA 4A3DD 4BBSD 3NCBA 2E9WC 1RW5A 3HOUD 1ILKA 4BXXD 3D87A 1EERA 1FG9A 2Z3QA 1CNT1 2R7ZD 4PS4A 3NCCA 1V7MV 3QT2C 4WRLB 4RS1A 1ITMA 4A3ED 2JA7D 3L5XA 5IYDD 3PO2D 1IARA 2Z3RA 1CD9A 1M4RA 1HWGA 1WU3I 3NCEA 3QAZA 3DI3A 2ERJD 4ZS7A 4A3LD 5IYCD 2CYKA 3UEZE 4FA8E 2B91A 1BGCA 3BPLA 5D22A 3UF2A 3N0PA 3HOVD 5E4EA 2B63D 1GA3A 1A22A 3OG4A 4J4LC 2R93D 5C3ED 3H0GD 3Q1SI 1RFBA 3H3VE 1J7VL 4EXPA 4YQXA 1EVSA 3QB1A 3I4MD 1IRLA 3B5KA 5L6YC 5D71A 1Y14A 4GS7A 4O6KA 1EMRA 1IL6A 1F45B 1NBPA 3D85C 1PY2A 2C35A 3NPZA 3NCFA 4Z5RD 5TS9A 4DKEA 3I4ND 1QVNA 1AXIA 1D9CA 1PW6A 3HOWD 3HHCA 1ETEA 1F6FA 2H24A 1HGUA 5FUCA 1BGDA 5C7XA 2Q98A 1M4BA 4NKQC 1AU1A 1Z7CA 3S9DA 5FLMD 1EKUA 2HYMB 3PIVA 3SE3B 1B5LA 3QWRB 3HMXB 3D48P 1Y6NL 3QB7A 4BBRD 1IK0A 1CSGA 1ITIA 2PSMA 4BY1D 4A3CD 1M47A 2B90A 1RHGA 4A3FD 1Y6KL 1HUWA 2O27A 4YDYI 2INTA 1KF9A 4NN5A 4I77Z 4CNIC 2LMSA 1N1FA 3DGCL 1BGEA 4DOHA 4NEJA 5D28B 1AX8A 3MZGA 1JLIA 4GRWA 5IYBD 4A3ID 1BCNA 4X51A 2ILKA 1EXZA 1FYHA 1LQSL 2B8YA 3DLQI 4NN6A 2VUMD 4A93D 2JA5D 5C4XD 5IP9D 1LKIA 1PGRA 1BBNA 1Y1WD 3IRHA 3BPNA 2GMFA 1BUYA 5FHXA 1Y1VD 1IJZA 4NN7A 1M48A 1HWHA 2L3OA 3VA2A 4YPGC 3L5WI 3TGXB 3G9VB 3PIWA 2L3YA 4O9HA 3EW3A 3G6DA 2Q14A 2O26A 3UX9A 4A3MD 2R92D 1CN4C 2B8ZA 3INKC 3BESL 2D9QA 3WCYI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NN6 A;  4NN5 A;  4NN7 A; 
#chains in the Genus database with same CATH topology
 4YUE C;  1GNC A;  1PVH B;  5D72 A;  4LDS A;  4NI9 A;  2Q7N B;  3EJJ A;  1HIK A;  2B8X A;  3OQ3 A;  2B5I A;  1I1R B;  1CYL A;  3DI2 A;  5EQH A;  5KNH I;  5D70 A;  1INR A;  3HHR A;  1RW5 A;  3HOU D;  1ILK A;  1EER A;  2R7Z D;  4PS4 A;  3QT2 C;  4A3E D;  3DI3 A;  4ZS7 A;  5D22 A;  3BPL A;  2B63 D;  3OG4 A;  1RFB A;  1J7V L;  4YQX A;  1IRL A;  1Y14 A;  4GS7 A;  4O6K A;  3NPZ A;  4Z5R D;  4YBQ A;  3NCF A;  1QVN A;  1AXI A;  3HHC A;  5FUC A;  4J05 A;  4IU9 A;  1EKU A;  4BBR D;  1IK0 A;  1RHG A;  1HUW A;  2O27 A;  5EQI A;  4D2B A;  4YDY I;  1KF9 A;  2LMS A;  3DGC L;  5IYB D;  4JA3 A;  1EXZ A;  1FYH A;  1LQS L;  5FHX A;  4NN7 A;  1HWH A;  4O9H A;  3EW3 A;  3UF5 A;  2LAG A;  1V7N V;  1YKB A;  4LRL A;  3N06 A;  1D9G A;  4DKF A;  3SE4 B;  4DKC A;  5A2O A;  2O6I A;  3LB6 A;  1M4A A;  1M4C A;  2IL6 A;  4U4W A;  5C44 D;  1SCF A;  4YB9 D;  4BY7 D;  1HUL A;  4MHL A;  2B8U A;  1WCM D;  1BP3 A;  1RCB A;  3NCB A;  2CFP A;  3D87 A;  4WRL B;  3PO2 D;  4ZYR A;  3NCE A;  2D9Q A;  4GBZ A;  5IYC D;  2CYK A;  5A2N A;  4FA8 E;  2B91 A;  1GA3 A;  1A22 A;  4J4L C;  4ZWB A;  4XNI A;  3I4M D;  3B5K A;  4IKX A;  1EMR A;  1NBP A;  3D85 C;  3O7P A;  5TS9 A;  1D9C A;  1ETE A;  1HGU A;  1BGD A;  1PV7 A;  1M4B A;  4NKQ C;  2HYM B;  3PIV A;  1B5L A;  4JRE A;  3HMX B;  4A3C D;  2V8N A;  4A3F D;  4NN5 A;  4I77 Z;  4GBY A;  2R92 D;  4A3I D;  4NEJ A;  1AX8 A;  3MZG A;  1JLI A;  4GRW A;  4X51 A;  4NN6 A;  4A93 D;  5IP9 D;  1LKI A;  4IU8 A;  4IKY A;  4APS A;  4OH3 A;  3G9V B;  2L3Y A;  3O7Q A;  2O26 A;  3UX9 A;  4A3M D;  4TPH A;  3WCY I;  3HOY D;  4Q65 A;  5IP7 D;  3OG6 A;  4A3J D;  1A7M A;  4A3B D;  2KZ1 A;  1HZI A;  1P9M B;  3LB6 B;  3WDO A;  5LQB A;  4EXN A;  2JA8 D;  2JA6 D;  1LK3 A;  4DKD A;  1Z92 A;  3BPO A;  1Y6M L;  4OAA A;  3AYH A;  4A3G D;  2OQP A;  4D2C A;  1PW4 A;  4LEP A;  1HIJ A;  4BXX D;  3NCC A;  4PYP A;  4RS1 A;  1ITM A;  5IYD D;  2Z3R A;  1CD9 A;  1M4R A;  1HWG A;  4IKV A;  2CFQ A;  4A3L D;  3UEZ E;  3UF2 A;  3HOV D;  5C3E D;  3H0G D;  3H3V E;  4EXP A;  3QB1 A;  1F45 B;  4DKE A;  1PY2 A;  2C35 A;  3I4N D;  4U4T A;  2H24 A;  4IKZ A;  1AU1 A;  4ZWC A;  3QB7 A;  1Y6N L;  1CSG A;  1ITI A;  2PSM A;  1PV6 A;  4CNI C;  1N1F A;  1BGE A;  4XNJ A;  4DOH A;  3DLQ I;  3IRH A;  3BPN A;  2GMF A;  1M48 A;  4U4V A;  3VA2 A;  4YPG C;  3TGX B;  3PIW A;  2Q14 A;  1CN4 C;  4D2D A;  1ITL A;  3HOZ D;  1ALU A;  5D58 A;  3HOX D;  1ITF A;  2D48 A;  3DUH C;  4TPG A;  5EQG A;  4NEM A;  4NI7 A;  4A3K D;  2XQB A;  1M49 A;  3FKI D;  3PO3 D;  1VLK A;  4ZF7 A;  4ZW9 A;  2XUT A;  4BBS D;  4A3D D;  2E9W C;  1FG9 A;  2Z3Q A;  4JR9 A;  1CNT 1;  4GC0 A;  1V7M V;  2JA7 D;  3L5X A;  2Y5Y A;  1IAR A;  1WU3 I;  3QAZ A;  2ERJ D;  4IKW A;  1BGC A;  3N0P A;  5E4E A;  4TPJ A;  3Q1S I;  1EVS A;  5L6Y C;  4W6V A;  5D71 A;  2R93 D;  1IL6 A;  5C65 A;  4UVM A;  1PW6 A;  5GXB A;  3HOW D;  1F6F A;  5C7X A;  2Q98 A;  1Z7C A;  3S9D A;  5FLM D;  3SE3 B;  3QWR B;  3D48 P;  4BY1 D;  1M47 A;  2B90 A;  1Y6K L;  2INT A;  1BCN A;  2ILK A;  5D6K A;  2VUM D;  2B8Y A;  5C4X D;  2JA5 D;  4QIQ A;  1PGR A;  1BBN A;  1Y1W D;  1BUY A;  5D59 A;  1Y1V D;  1IJZ A;  2L3O A;  3L5W I;  3G6D A;  2B8Z A;  3INK C;  3BES L;  5D28 B; 
#chains in the Genus database with same CATH homology
 4YUE C;  1GNC A;  1PVH B;  3HOY D;  5D72 A;  3UF5 A;  2LAG A;  1ITL A;  5IP7 D;  1V7N V;  1YKB A;  3OG6 A;  4NI9 A;  2Q7N B;  3HOZ D;  1ALU A;  4LRL A;  4A3J D;  3N06 A;  1A7M A;  3EJJ A;  3HOX D;  1D9G A;  1HIK A;  2B8X A;  4A3B D;  4DKF A;  2KZ1 A;  1ITF A;  2D48 A;  3SE4 B;  1HZI A;  1P9M B;  3OQ3 A;  3DUH C;  3LB6 B;  4DKC A;  5LQB A;  4EXN A;  2JA8 D;  2JA6 D;  2B5I A;  1LK3 A;  2O6I A;  4NEM A;  4NI7 A;  3LB6 A;  4DKD A;  4A3K D;  1I1R B;  1M4A A;  1M4C A;  1CYL A;  3DI2 A;  2IL6 A;  1Z92 A;  2XQB A;  5C44 D;  1M49 A;  1SCF A;  3FKI D;  3PO3 D;  1VLK A;  4BY7 D;  3BPO A;  4ZF7 A;  1HUL A;  1Y6M L;  4MHL A;  3AYH A;  2B8U A;  4A3G D;  2OQP A;  5KNH I;  1WCM D;  1BP3 A;  1INR A;  5D70 A;  1HIJ A;  1RCB A;  3HHR A;  4A3D D;  4BBS D;  3NCB A;  2E9W C;  1RW5 A;  3HOU D;  1ILK A;  4BXX D;  3D87 A;  1EER A;  1FG9 A;  2Z3Q A;  1CNT 1;  2R7Z D;  4PS4 A;  3NCC A;  1V7M V;  3QT2 C;  4WRL B;  4RS1 A;  1ITM A;  4A3E D;  2JA7 D;  3L5X A;  5IYD D;  3PO2 D;  1IAR A;  2Z3R A;  1CD9 A;  1M4R A;  1HWG A;  1WU3 I;  3NCE A;  3QAZ A;  3DI3 A;  2ERJ D;  4ZS7 A;  4A3L D;  5IYC D;  2CYK A;  3UEZ E;  4FA8 E;  2B91 A;  1BGC A;  3BPL A;  5D22 A;  3UF2 A;  3N0P A;  3HOV D;  5E4E A;  2B63 D;  1GA3 A;  1A22 A;  3OG4 A;  4J4L C;  2R93 D;  5C3E D;  3H0G D;  3Q1S I;  1RFB A;  3H3V E;  1J7V L;  4EXP A;  4YQX A;  1EVS A;  3QB1 A;  3I4M D;  1IRL A;  3B5K A;  5L6Y C;  5D71 A;  1Y14 A;  4GS7 A;  4O6K A;  1EMR A;  1IL6 A;  1F45 B;  1NBP A;  3D85 C;  1PY2 A;  2C35 A;  3NPZ A;  3NCF A;  4Z5R D;  5TS9 A;  4DKE A;  3I4N D;  1QVN A;  1AXI A;  1D9C A;  1PW6 A;  3HOW D;  3HHC A;  1ETE A;  1F6F A;  2H24 A;  1HGU A;  5FUC A;  1BGD A;  5C7X A;  2Q98 A;  1M4B A;  4NKQ C;  1AU1 A;  1Z7C A;  3S9D A;  5FLM D;  1EKU A;  2HYM B;  3PIV A;  3SE3 B;  1B5L A;  3QWR B;  3HMX B;  3D48 P;  1Y6N L;  3QB7 A;  4BBR D;  1IK0 A;  1CSG A;  1ITI A;  2PSM A;  4BY1 D;  4A3C D;  1M47 A;  2B90 A;  1RHG A;  4A3F D;  1Y6K L;  1HUW A;  2O27 A;  4YDY I;  2INT A;  1KF9 A;  4NN5 A;  4I77 Z;  4CNI C;  2LMS A;  1N1F A;  3DGC L;  1BGE A;  4DOH A;  4NEJ A;  5D28 B;  1AX8 A;  3MZG A;  1JLI A;  4GRW A;  5IYB D;  4A3I D;  1BCN A;  4X51 A;  2ILK A;  1EXZ A;  1FYH A;  1LQS L;  2B8Y A;  3DLQ I;  4NN6 A;  2VUM D;  4A93 D;  2JA5 D;  5C4X D;  5IP9 D;  1LKI A;  1PGR A;  1BBN A;  1Y1W D;  3IRH A;  3BPN A;  2GMF A;  1BUY A;  5FHX A;  1Y1V D;  1IJZ A;  4NN7 A;  1M48 A;  1HWH A;  2L3O A;  3VA2 A;  4YPG C;  3L5W I;  3TGX B;  3G9V B;  3PIW A;  2L3Y A;  4O9H A;  3EW3 A;  3G6D A;  2Q14 A;  2O26 A;  3UX9 A;  4A3M D;  2R92 D;  1CN4 C;  2B8Z A;  3INK C;  3BES L;  2D9Q A;  3WCY I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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