4NN6A

Cytokine receptor complex - crystal form 1b
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
118
structure length
101
Chain Sequence
FSNCNFTSITKIYCNIIFHDLTGDLKGAKFEQIEDCESKPACLLKIEYYTLNPIPGCPSLPDKTFARRTREALNDHCPVQNICLQQTSQILRLWYSFMQSP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of the proinflammatory signaling complex mediated by TSLP.
pubmed doi rcsb
molecule tags Cytokine/cytokine receptor
source organism Mus musculus
molecule keywords Thymic stromal lymphopoietin
total genus 34
structure length 101
sequence length 118
ec nomenclature
pdb deposition date 2013-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF15216 TSLP Thymic stromal lymphopoietin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.90 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 4nn6A00
4NN6A 4NN5A 4NN7A
chains in the Genus database with same CATH superfamily
4DKEA 1Y6NL 4NN6A 5IYBD 4D2BA 2D9QA 5D71A 1GA3A 4ZYRA 3PIWA 4ZF7A 1PGRA 4IKZA 1EERA 3G6DA 1RHGA 2Y5YA 1AU1A 3NPZA 1LKIA 3N0PA 1CNT1 3DUHC 2KZ1A 2B90A 3L5XA 3UEZE 1BCNA 3TGXB 4RS1A 3HHCA 4ZWBA 3BPLA 3SE3B 2GMFA 4LEPA 2O27A 4IKVA 1HUWA 5D6KA 2C35A 1Y1WD 2H24A 4BBSD 1M49A 1AXIA 2JA7D 4ZWCA 3SE4B 4YDYI 4A3ED 2O6IA 1AX8A 1ALUA 1CYLA 3HOWD 2B8ZA 1BBNA 4JREA 5IYCD 2CFPA 3MZGA 4NN5A 1D9GA 5FLMD 3NCFA 5C3ED 4CNIC 3O7PA 4D2DA 4GBYA 3OQ3A 5KNHI 1ITIA 1JLIA 1V7NV 4D2CA 4A3KD 1M4CA 1NBPA 5C7XA 3N06A 3D48P 5D28B 3VA2A 3EJJA 3QWRB 1M4BA 4GRWA 1YKBA 4A3ID 4J05A 3UF5A 3DLQI 3LB6A 4TPHA 4YQXA 4J4LC 4A3GD 1IJZA 2ERJD 4IKYA 5D70A 3H0GD 4NEJA 1EVSA 2LAGA 4U4TA 1PW6A 1BUYA 2O26A 3NCEA 4APSA 4Q65A 1BGCA 1GNCA 3INKC 2L3YA 1Y14A 3QB1A 3QT2C 4TPJA 1Z7CA 3NCCA 3AYHA 2R93D 1WU3I 2E9WC 1Y6ML 1HWHA 4YUEC 1PV6A 1EMRA 2Z3RA 1P9MB 1HIKA 1LQSL 1VLKA 4BXXD 3WDOA 5C44D 3HOYD 1CD9A 4A3LD 5C4XD 3L5WI 1F6FA 1PY2A 5A2OA 4EXPA 5EQGA 2Q14A 1M48A 2CFQA 1HULA 3G9VB 2B5IA 1RW5A 3PO3D 2HYMB 4GC0A 5GXBA 2Q7NB 2OQPA 1J7VL 5D72A 1BGEA 4YB9D 1SCFA 4A3BD 3PO2D 4O6KA 1M4AA 1PW4A 2Z3QA 4WRLB 1ITFA 4U4WA 1INRA 2R7ZD 3UF2A 2B8XA 5D22A 2INTA 2JA5D 4UVMA 4YPGC 3UX9A 4OH3A 4DKDA 3HMXB 4NN7A 4ZS7A 5FUCA 4LDSA 4IKWA 4BBRD 4FA8E 4DOHA 4A93D 2JA8D 4QIQA 4JR9A 3QAZA 3DGCL 3OG4A 4NI9A 1WCMD 4A3CD 1PVHB 2IL6A 2PSMA 5C65A 1IK0A 1EXZA 3HOUD 4IU8A 1HGUA 3I4ND 4IU9A 4OAAA 3HOZD 5D58A 1PV7A 3O7QA 4GBZA 1CN4C 2LMSA 1M4RA 4A3JD 1BGDA 1M47A 4DKCA 3H3VE 3I4MD 2XQBA 1RFBA 1Z92A 5A2NA 3DI2A 1N1FA 1Y6KL 4X51A 3OG6A 4NI7A 1ETEA 1A22A 3IRHA 4PS4A 4XNJA 4NKQC 5E4EA 4A3DD 4PYPA 2R92D 5EQIA 3BPNA 1I1RB 1CSGA 1D9CA 2B8UA 3HOVD 1HIJA 2L3OA 5LQBA 3Q1SI 3BPOA 3PIVA 1Y1VD 3NCBA 4LRLA 1IL6A 5TS9A 3DI3A 3D85C 3BESL 5L6YC 2V8NA 3FKID 4JA3A 4U4VA 1FYHA 3HHRA 1HWGA 2B63D 1V7MV 1LK3A 4XNIA 3EW3A 4BY7D 4DKFA 1FG9A 1ITLA 2ILKA 5IP7D 4TPGA 4MHLA 1ILKA 5IP9D 2CYKA 4A3FD 3S9DA 4I77Z 4YBQA 3WCYI 2B8YA 3LB6B 5EQHA 1QVNA 4NEMA 1HZIA 2Q98A 4GS7A 4O9HA 4W6VA 2B91A 5D59A 4BY1D 4IKXA 5IYDD 3HOXD 1IRLA 4Z5RD 1A7MA 2VUMD 4A3MD 1EKUA 1RCBA 3QB7A 1IARA 1ITMA 1B5LA 3D87A 4ZW9A 1BP3A 1KF9A 5FHXA 1F45B 3B5KA 2XUTA 4EXNA 2JA6D 2D48A
chains in the Genus database with same CATH topology
2Z3QA 4DKEA 2B8UA 3VA2A 3EJJA 4WRLB 1ITFA 1INRA 3QWRB 1Y6NL 1M4BA 3HOVD 1HIJA 2L3OA 4GRWA 1YKBA 4NN6A 5LQBA 3Q1SI 3BPOA 2R7ZD 4A3ID 3UF5A 3UF2A 2B8XA 3DLQI 1CSGA 3PIVA 5IYBD 5D22A 2D9QA 1Y1VD 2INTA 3LB6A 3NCBA 4LRLA 2JA5D 1IL6A 5D71A 1GA3A 5TS9A 3DI3A 3D85C 3BESL 5L6YC 3PIWA 4YQXA 3FKID 4J4LC 1PGRA 4YPGC 3UX9A 4ZF7A 4A3GD 4DKDA 1IJZA 1EERA 1FYHA 3G6DA 1RHGA 3HMXB 4NN7A 3HHRA 2ERJD 1HWGA 2B63D 1AU1A 4ZS7A 3NPZA 1LKIA 3N0PA 5FUCA 1CNT1 5D70A 3DUHC 2KZ1A 3H0GD 1V7MV 1LK3A 2B90A 4NEJA 4BBRD 1EVSA 2LAGA 4FA8E 1PW6A 4DOHA 4A93D 3EW3A 1BUYA 3L5XA 2JA8D 4BY7D 2O26A 3NCEA 3UEZE 4DKFA 1FG9A 1BCNA 1ITLA 2ILKA 1BGCA 3TGXB 5IP7D 4MHLA 3QAZA 1ILKA 4RS1A 3DGCL 3OG4A 4NI9A 1GNCA 5IP9D 1WCMD 3INKC 3HHCA 4A3CD 2L3YA 3BPLA 1PVHB 2IL6A 2PSMA 2GMFA 3SE3B 1Y14A 2O27A 3QB1A 3QT2C 1HUWA 1IK0A 2CYKA 2C35A 1EXZA 1Z7CA 3NCCA 3HOUD 4A3FD 3S9DA 3AYHA 4I77Z 1Y1WD 1HGUA 2H24A 3I4ND 3WCYI 4BBSD 1M49A 1AXIA 2R92D 2R93D 2JA7D 1WU3I 2E9WC 3SE4B 2B8YA 3LB6B 3HOZD 4YDYI 1Y6ML 1HWHA 1QVNA 4A3ED 4NEMA 2O6IA 4YUEC 2Z3RA 1EMRA 1HZIA 1P9MB 2Q98A 1AX8A 1HIKA 4GS7A 1LQSL 1VLKA 4BXXD 1ALUA 1CYLA 4O9HA 2B91A 4BY1D 3HOWD 5C44D 2B8ZA 3HOXD 5IYDD 1IRLA 3HOYD 1BBNA 1CN4C 2LMSA 4Z5RD 1A7MA 1CD9A 1M4RA 4A3LD 5C4XD 2VUMD 3L5WI 4A3JD 1F6FA 1BGDA 1M47A 5IYCD 1PY2A 4DKCA 3H3VE 4EXPA 3I4MD 3MZGA 4NN5A 4A3MD 1EKUA 2Q14A 2XQBA 1M48A 1RCBA 1D9GA 1RFBA 1IARA 3QB7A 5FLMD 1HULA 1ITMA 3G9VB 2B5IA 3NCFA 5C3ED 1RW5A 3PO3D 1B5LA 1Z92A 2HYMB 3D48P 1N1FA 3D87A 1Y6KL 3DI2A 4CNIC 4X51A 2Q7NB 2OQPA 1BP3A 1J7VL 1KF9A 3OG6A 3OQ3A 5D72A 5KNHI 4NI7A 1ETEA 1ITIA 1A22A 1JLIA 1BGEA 1V7NV 3IRHA 4PS4A 5FHXA 1F45B 1SCFA 4A3KD 1M4CA 1NBPA 4NKQC 5E4EA 3PO2D 4A3BD 4A3DD 4O6KA 1M4AA 3B5KA 4EXNA 5C7XA 3N06A 2JA6D 2D48A 5D28B 3BPNA 1I1RB 1D9CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NN6 A;  4NN5 A;  4NN7 A; 
#chains in the Genus database with same CATH topology
 4DKE A;  1Y6N L;  4NN6 A;  5IYB D;  4D2B A;  2D9Q A;  5D71 A;  1GA3 A;  4ZYR A;  3PIW A;  4ZF7 A;  1PGR A;  4IKZ A;  1EER A;  3G6D A;  1RHG A;  2Y5Y A;  1AU1 A;  3NPZ A;  1LKI A;  3N0P A;  1CNT 1;  3DUH C;  2KZ1 A;  2B90 A;  3L5X A;  3UEZ E;  1BCN A;  3TGX B;  4RS1 A;  3HHC A;  4ZWB A;  3BPL A;  3SE3 B;  2GMF A;  4LEP A;  2O27 A;  4IKV A;  1HUW A;  5D6K A;  2C35 A;  1Y1W D;  2H24 A;  4BBS D;  1M49 A;  1AXI A;  2JA7 D;  4ZWC A;  3SE4 B;  4YDY I;  4A3E D;  2O6I A;  1AX8 A;  1ALU A;  1CYL A;  3HOW D;  2B8Z A;  1BBN A;  4JRE A;  5IYC D;  2CFP A;  3MZG A;  4NN5 A;  1D9G A;  5FLM D;  3NCF A;  5C3E D;  4CNI C;  3O7P A;  4D2D A;  4GBY A;  3OQ3 A;  5KNH I;  1ITI A;  1JLI A;  1V7N V;  4D2C A;  4A3K D;  1M4C A;  1NBP A;  5C7X A;  3N06 A;  3D48 P;  5D28 B;  3VA2 A;  3EJJ A;  3QWR B;  1M4B A;  4GRW A;  1YKB A;  4A3I D;  4J05 A;  3UF5 A;  3DLQ I;  3LB6 A;  4TPH A;  4YQX A;  4J4L C;  4A3G D;  1IJZ A;  2ERJ D;  4IKY A;  5D70 A;  3H0G D;  4NEJ A;  1EVS A;  2LAG A;  4U4T A;  1PW6 A;  1BUY A;  2O26 A;  3NCE A;  4APS A;  4Q65 A;  1BGC A;  1GNC A;  3INK C;  2L3Y A;  1Y14 A;  3QB1 A;  3QT2 C;  4TPJ A;  1Z7C A;  3NCC A;  3AYH A;  2R93 D;  1WU3 I;  2E9W C;  1Y6M L;  1HWH A;  4YUE C;  1PV6 A;  1EMR A;  2Z3R A;  1P9M B;  1HIK A;  1LQS L;  1VLK A;  4BXX D;  3WDO A;  5C44 D;  3HOY D;  1CD9 A;  4A3L D;  5C4X D;  3L5W I;  1F6F A;  1PY2 A;  5A2O A;  4EXP A;  5EQG A;  2Q14 A;  1M48 A;  2CFQ A;  1HUL A;  3G9V B;  2B5I A;  1RW5 A;  3PO3 D;  2HYM B;  4GC0 A;  5GXB A;  2Q7N B;  2OQP A;  1J7V L;  5D72 A;  1BGE A;  4YB9 D;  1SCF A;  4A3B D;  3PO2 D;  4O6K A;  1M4A A;  1PW4 A;  2Z3Q A;  4WRL B;  1ITF A;  4U4W A;  1INR A;  2R7Z D;  3UF2 A;  2B8X A;  5D22 A;  2INT A;  2JA5 D;  4UVM A;  4YPG C;  3UX9 A;  4OH3 A;  4DKD A;  3HMX B;  4NN7 A;  4ZS7 A;  5FUC A;  4LDS A;  4IKW A;  4BBR D;  4FA8 E;  4DOH A;  4A93 D;  2JA8 D;  4QIQ A;  4JR9 A;  3QAZ A;  3DGC L;  3OG4 A;  4NI9 A;  1WCM D;  4A3C D;  1PVH B;  2IL6 A;  2PSM A;  5C65 A;  1IK0 A;  1EXZ A;  3HOU D;  4IU8 A;  1HGU A;  3I4N D;  4IU9 A;  4OAA A;  3HOZ D;  5D58 A;  1PV7 A;  3O7Q A;  4GBZ A;  1CN4 C;  2LMS A;  1M4R A;  4A3J D;  1BGD A;  1M47 A;  4DKC A;  3H3V E;  3I4M D;  2XQB A;  1RFB A;  1Z92 A;  5A2N A;  3DI2 A;  1N1F A;  1Y6K L;  4X51 A;  3OG6 A;  4NI7 A;  1ETE A;  1A22 A;  3IRH A;  4PS4 A;  4XNJ A;  4NKQ C;  5E4E A;  4A3D D;  4PYP A;  2R92 D;  5EQI A;  3BPN A;  1I1R B;  1CSG A;  1D9C A;  2B8U A;  3HOV D;  1HIJ A;  2L3O A;  5LQB A;  3Q1S I;  3BPO A;  3PIV A;  1Y1V D;  3NCB A;  4LRL A;  1IL6 A;  5TS9 A;  3DI3 A;  3D85 C;  3BES L;  5L6Y C;  2V8N A;  3FKI D;  4JA3 A;  4U4V A;  1FYH A;  3HHR A;  1HWG A;  2B63 D;  1V7M V;  1LK3 A;  4XNI A;  3EW3 A;  4BY7 D;  4DKF A;  1FG9 A;  1ITL A;  2ILK A;  5IP7 D;  4TPG A;  4MHL A;  1ILK A;  5IP9 D;  2CYK A;  4A3F D;  3S9D A;  4I77 Z;  4YBQ A;  3WCY I;  2B8Y A;  3LB6 B;  5EQH A;  1QVN A;  4NEM A;  1HZI A;  2Q98 A;  4GS7 A;  4O9H A;  4W6V A;  2B91 A;  5D59 A;  4BY1 D;  4IKX A;  5IYD D;  3HOX D;  1IRL A;  4Z5R D;  1A7M A;  2VUM D;  4A3M D;  1EKU A;  1RCB A;  3QB7 A;  1IAR A;  1ITM A;  1B5L A;  3D87 A;  4ZW9 A;  1BP3 A;  1KF9 A;  5FHX A;  1F45 B;  3B5K A;  2XUT A;  4EXN A;  2JA6 D;  2D48 A; 
#chains in the Genus database with same CATH homology
 2Z3Q A;  4DKE A;  2B8U A;  3VA2 A;  3EJJ A;  4WRL B;  1ITF A;  1INR A;  3QWR B;  1Y6N L;  1M4B A;  3HOV D;  1HIJ A;  2L3O A;  4GRW A;  1YKB A;  4NN6 A;  5LQB A;  3Q1S I;  3BPO A;  2R7Z D;  4A3I D;  3UF5 A;  3UF2 A;  2B8X A;  3DLQ I;  1CSG A;  3PIV A;  5IYB D;  5D22 A;  2D9Q A;  1Y1V D;  2INT A;  3LB6 A;  3NCB A;  4LRL A;  2JA5 D;  1IL6 A;  5D71 A;  1GA3 A;  5TS9 A;  3DI3 A;  3D85 C;  3BES L;  5L6Y C;  3PIW A;  4YQX A;  3FKI D;  4J4L C;  1PGR A;  4YPG C;  3UX9 A;  4ZF7 A;  4A3G D;  4DKD A;  1IJZ A;  1EER A;  1FYH A;  3G6D A;  1RHG A;  3HMX B;  4NN7 A;  3HHR A;  2ERJ D;  1HWG A;  2B63 D;  1AU1 A;  4ZS7 A;  3NPZ A;  1LKI A;  3N0P A;  5FUC A;  1CNT 1;  5D70 A;  3DUH C;  2KZ1 A;  3H0G D;  1V7M V;  1LK3 A;  2B90 A;  4NEJ A;  4BBR D;  1EVS A;  2LAG A;  4FA8 E;  1PW6 A;  4DOH A;  4A93 D;  3EW3 A;  1BUY A;  3L5X A;  2JA8 D;  4BY7 D;  2O26 A;  3NCE A;  3UEZ E;  4DKF A;  1FG9 A;  1BCN A;  1ITL A;  2ILK A;  1BGC A;  3TGX B;  5IP7 D;  4MHL A;  3QAZ A;  1ILK A;  4RS1 A;  3DGC L;  3OG4 A;  4NI9 A;  1GNC A;  5IP9 D;  1WCM D;  3INK C;  3HHC A;  4A3C D;  2L3Y A;  3BPL A;  1PVH B;  2IL6 A;  2PSM A;  2GMF A;  3SE3 B;  1Y14 A;  2O27 A;  3QB1 A;  3QT2 C;  1HUW A;  1IK0 A;  2CYK A;  2C35 A;  1EXZ A;  1Z7C A;  3NCC A;  3HOU D;  4A3F D;  3S9D A;  3AYH A;  4I77 Z;  1Y1W D;  1HGU A;  2H24 A;  3I4N D;  3WCY I;  4BBS D;  1M49 A;  1AXI A;  2R92 D;  2R93 D;  2JA7 D;  1WU3 I;  2E9W C;  3SE4 B;  2B8Y A;  3LB6 B;  3HOZ D;  4YDY I;  1Y6M L;  1HWH A;  1QVN A;  4A3E D;  4NEM A;  2O6I A;  4YUE C;  2Z3R A;  1EMR A;  1HZI A;  1P9M B;  2Q98 A;  1AX8 A;  1HIK A;  4GS7 A;  1LQS L;  1VLK A;  4BXX D;  1ALU A;  1CYL A;  4O9H A;  2B91 A;  4BY1 D;  3HOW D;  5C44 D;  2B8Z A;  3HOX D;  5IYD D;  1IRL A;  3HOY D;  1BBN A;  1CN4 C;  2LMS A;  4Z5R D;  1A7M A;  1CD9 A;  1M4R A;  4A3L D;  5C4X D;  2VUM D;  3L5W I;  4A3J D;  1F6F A;  1BGD A;  1M47 A;  5IYC D;  1PY2 A;  4DKC A;  3H3V E;  4EXP A;  3I4M D;  3MZG A;  4NN5 A;  4A3M D;  1EKU A;  2Q14 A;  2XQB A;  1M48 A;  1RCB A;  1D9G A;  1RFB A;  1IAR A;  3QB7 A;  5FLM D;  1HUL A;  1ITM A;  3G9V B;  2B5I A;  3NCF A;  5C3E D;  1RW5 A;  3PO3 D;  1B5L A;  1Z92 A;  2HYM B;  3D48 P;  1N1F A;  3D87 A;  1Y6K L;  3DI2 A;  4CNI C;  4X51 A;  2Q7N B;  2OQP A;  1BP3 A;  1J7V L;  1KF9 A;  3OG6 A;  3OQ3 A;  5D72 A;  5KNH I;  4NI7 A;  1ETE A;  1ITI A;  1A22 A;  1JLI A;  1BGE A;  1V7N V;  3IRH A;  4PS4 A;  5FHX A;  1F45 B;  1SCF A;  4A3K D;  1M4C A;  1NBP A;  4NKQ C;  5E4E A;  3PO2 D;  4A3B D;  4A3D D;  4O6K A;  1M4A A;  3B5K A;  4EXN A;  5C7X A;  3N06 A;  2JA6 D;  2D48 A;  5D28 B;  3BPN A;  1I1R B;  1D9C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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