4PYPA

Crystal structure of the human glucose transporter glut1
Total Genus 166
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
166
sequence length
447
structure length
447
Chain Sequence
TGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYTQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVQRAGRRTLHLIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPET
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the human glucose transporter GLUT1
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Solute carrier family 2, facilitated glucose transporter mem
total genus 166
structure length 447
sequence length 447
ec nomenclature
pdb deposition date 2014-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4pypA00
4IKXA 4U4WA 4Q65A 5C65A 4JA3A 2CFQA 4XNJA 4LDSA 2Y5YA 4IU9A 5EQHA 4U4VA 5A2OA 3O7PA 4IKVA 4GC0A 4ZYRA 4ZW9A 4OAAA 4IKYA 4OH3A 4IU8A 4U4TA 4J05A 4ZWCA 5EQIA 4W6VA 5GXBA 4UVMA 4JREA 4JR9A 2V8NA 4TPHA 1PW4A 4TPGA 4GBZA 4XNIA 4IKZA 4TPJA 4GBYA 4ZWBA 5D6KA 4YBQA 4IKWA 4D2DA 5A2NA 5D59A 2XUTA 4YB9D 1PV7A 4PYPA 3WDOA 4D2CA 5EQGA 5D58A 3O7QA 1PV6A 2CFPA 4LEPA 4QIQA 4APSA 4D2BA
chains in the Genus database with same CATH superfamily
3D48P 3HOUD 2L3YA 1EVSA 1Z92A 1M4AA 3O7PA 1ILKA 5D72A 1INRA 4YDYI 1CYLA 4IKZA 3BPOA 3WDOA 5EQGA 3NCFA 3I4MD 1WU3I 2CYKA 4IKXA 1A22A 1BUYA 2C35A 2H24A 1HUWA 3DUHC 4EXPA 2O26A 5C4XD 4X51A 1ITLA 4TPHA 3HOVD 5D70A 3L5WI 3IRHA 4DKCA 3Q1SI 1IJZA 1FG9A 1I1RB 4BBRD 1FYHA 1SCFA 2ILKA 2Y5YA 3HMXB 4NKQC 3N0PA 1RW5A 5EQIA 4JR9A 4GBZA 4XNIA 4WRLB 4IKWA 4D2DA 1BGCA 5D59A 3INKC 2R7ZD 4A93D 1PV6A 4A3MD 2JA8D 4A3BD 2CFQA 2KZ1A 4ZS7A 1B5LA 2GMFA 4IKVA 4ZYRA 1A7MA 1EERA 5E4EA 4J05A 2IL6A 1PY2A 1HGUA 2JA7D 1AU1A 1RCBA 4YUEC 4LDSA 2E9WC 1HZIA 1Y6NL 1WCMD 4OH3A 5GXBA 2Z3RA 3HOYD 2V8NA 4EXNA 4YQXA 4YBQA 3DI3A 1P9MB 1M4RA 1AXIA 5D58A 2HYMB 5KNHI 3QB7A 5C65A 4BY1D 5IP9D 1QVNA 3QAZA 3QB1A 3UF5A 3H3VE 4U4VA 3G9VB 3L5XA 3PIVA 3NPZA 4U4TA 4BXXD 3OQ3A 4UVMA 1EXZA 4NI7A 3DLQI 5FLMD 4PYPA 4GS7A 3QT2C 3DI2A 3NCEA 4JA3A 3AYHA 4A3ED 3PO2D 3EW3A 1EMRA 3OG4A 1IARA 4IKYA 4LRLA 4DOHA 4PS4A 1PVHB 1ITFA 5C44D 2O27A 1LK3A 4XNJA 4DKFA 2O6IA 1Y1WD 1Y1VD 1M48A 1AX8A 2B8UA 1M4CA 3B5KA 1V7NV 1D9CA 1F6FA 4A3CD 2CFPA 4NEJA 2D9QA 3VA2A 4ZW9A 4IU8A 4JREA 4TPGA 3EJJA 1Y6KL 3D85C 5A2NA 4YB9D 2LMSA 5IP7D 1BCNA 4LEPA 4O9HA 1ITMA 1Z7CA 4U4WA 4A3KD 1ITIA 4FA8E 2D48A 1IK0A 1LQSL 2OQPA 2INTA 4W6VA 3HHCA 1CSGA 2VUMD 4TPJA 1NBPA 2R92D 1JLIA 4D2CA 4GRWA 1CNT1 2Q7NB 4APSA 5D71A 5FUCA 4Z5RD 3N06A 1M4BA 4A3JD 2L3OA 3BESL 3NCBA 2B91A 3DGCL 3NCCA 3BPNA 3TGXB 3HOXD 4J4LC 2Z3QA 1RFBA 1RHGA 3HOWD 2B63D 4RS1A 1M47A 4O6KA 2JA5D 2LAGA 1Y6ML 3FKID 4ZF7A 5L6YC 2PSMA 5EQHA 4NEMA 4OAAA 1KF9A 4A3LD 3QWRB 3UEZE 4NN5A 1M49A 1PW4A 3SE4B 2B8XA 2B8YA 2Q14A 5D6KA 1HULA 2XUTA 4A3FD 1IRLA 5IYBD 1V7MV 4D2BA 1CN4C 4QIQA 4Q65A 2R93D 1BBNA 4A3ID 3BPLA 2JA6D 1IL6A 5A2OA 1CD9A 3LB6A 3UX9A 5IYDD 3UF2A 4NI9A 4I77Z 3I4ND 2Q98A 4BBSD 3MZGA 1VLKA 5LQBA 5C7XA 3O7QA 1ALUA 3D87A 1BP3A 5C3ED 4DKEA 1HWHA 3H0GD 1PGRA 4ZWBA 3S9DA 3WCYI 5FHXA 1GNCA 1PW6A 3SE3B 1EKUA 2XQBA 5IYCD 4NN7A 5D28B 1HIJA 1Y14A 4DKDA 4IU9A 4A3GD 4A3DD 3PO3D 4GC0A 1F45B 4YPGC 1N1FA 4ZWCA 5TS9A 2B5IA 2ERJD 4GBYA 4CNIC 1HWGA 1GA3A 2B90A 4NN6A 4MHLA 5D22A 3LB6B 3PIWA 1LKIA 3HOZD 1D9GA 1BGDA 1HIKA 3G6DA 3OG6A 4BY7D 2B8ZA 1PV7A 1YKBA 1J7VL 3HHRA 1BGEA 1ETEA
chains in the Genus database with same CATH topology
4IKXA 4U4WA 4Q65A 5C65A 4JA3A 2CFQA 4XNJA 4LDSA 2Y5YA 4IU9A 5EQHA 4U4VA 5A2OA 3O7PA 4IKVA 4GC0A 4ZYRA 4ZW9A 4OAAA 4IKYA 4OH3A 4IU8A 4U4TA 4J05A 4ZWCA 5EQIA 4W6VA 5GXBA 4UVMA 4JREA 4JR9A 2V8NA 4TPHA 1PW4A 4TPGA 4GBZA 4XNIA 4IKZA 4TPJA 4GBYA 4ZWBA 5D6KA 4YBQA 4IKWA 4D2DA 5A2NA 5D59A 2XUTA 4YB9D 1PV7A 4PYPA 3WDOA 4D2CA 5EQGA 5D58A 3O7QA 1PV6A 2CFPA 4LEPA 4QIQA 4APSA 4D2BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IKX A;  4U4W A;  4Q65 A;  5C65 A;  4JA3 A;  2CFQ A;  4XNJ A;  4LDS A;  2Y5Y A;  4IU9 A;  5EQH A;  4U4V A;  5A2O A;  3O7P A;  4IKV A;  4GC0 A;  4ZYR A;  4ZW9 A;  4OAA A;  4IKY A;  4OH3 A;  4IU8 A;  4U4T A;  4J05 A;  4ZWC A;  5EQI A;  4W6V A;  5GXB A;  4UVM A;  4JRE A;  4JR9 A;  2V8N A;  4TPH A;  1PW4 A;  4TPG A;  4GBZ A;  4XNI A;  4IKZ A;  4TPJ A;  4GBY A;  4ZWB A;  5D6K A;  4YBQ A;  4IKW A;  4D2D A;  5A2N A;  5D59 A;  2XUT A;  4YB9 D;  1PV7 A;  4PYP A;  3WDO A;  4D2C A;  5EQG A;  5D58 A;  3O7Q A;  1PV6 A;  2CFP A;  4LEP A;  4QIQ A;  4APS A;  4D2B A; 
#chains in the Genus database with same CATH topology
 3D48 P;  3HOU D;  2L3Y A;  1EVS A;  1Z92 A;  1M4A A;  3O7P A;  1ILK A;  5D72 A;  1INR A;  4YDY I;  1CYL A;  4IKZ A;  3BPO A;  3WDO A;  5EQG A;  3NCF A;  3I4M D;  1WU3 I;  2CYK A;  4IKX A;  1A22 A;  1BUY A;  2C35 A;  2H24 A;  1HUW A;  3DUH C;  4EXP A;  2O26 A;  5C4X D;  4X51 A;  1ITL A;  4TPH A;  3HOV D;  5D70 A;  3L5W I;  3IRH A;  4DKC A;  3Q1S I;  1IJZ A;  1FG9 A;  1I1R B;  4BBR D;  1FYH A;  1SCF A;  2ILK A;  2Y5Y A;  3HMX B;  4NKQ C;  3N0P A;  1RW5 A;  5EQI A;  4JR9 A;  4GBZ A;  4XNI A;  4WRL B;  4IKW A;  4D2D A;  1BGC A;  5D59 A;  3INK C;  2R7Z D;  4A93 D;  1PV6 A;  4A3M D;  2JA8 D;  4A3B D;  2CFQ A;  2KZ1 A;  4ZS7 A;  1B5L A;  2GMF A;  4IKV A;  4ZYR A;  1A7M A;  1EER A;  5E4E A;  4J05 A;  2IL6 A;  1PY2 A;  1HGU A;  2JA7 D;  1AU1 A;  1RCB A;  4YUE C;  4LDS A;  2E9W C;  1HZI A;  1Y6N L;  1WCM D;  4OH3 A;  5GXB A;  2Z3R A;  3HOY D;  2V8N A;  4EXN A;  4YQX A;  4YBQ A;  3DI3 A;  1P9M B;  1M4R A;  1AXI A;  5D58 A;  2HYM B;  5KNH I;  3QB7 A;  5C65 A;  4BY1 D;  5IP9 D;  1QVN A;  3QAZ A;  3QB1 A;  3UF5 A;  3H3V E;  4U4V A;  3G9V B;  3L5X A;  3PIV A;  3NPZ A;  4U4T A;  4BXX D;  3OQ3 A;  4UVM A;  1EXZ A;  4NI7 A;  3DLQ I;  5FLM D;  4PYP A;  4GS7 A;  3QT2 C;  3DI2 A;  3NCE A;  4JA3 A;  3AYH A;  4A3E D;  3PO2 D;  3EW3 A;  1EMR A;  3OG4 A;  1IAR A;  4IKY A;  4LRL A;  4DOH A;  4PS4 A;  1PVH B;  1ITF A;  5C44 D;  2O27 A;  1LK3 A;  4XNJ A;  4DKF A;  2O6I A;  1Y1W D;  1Y1V D;  1M48 A;  1AX8 A;  2B8U A;  1M4C A;  3B5K A;  1V7N V;  1D9C A;  1F6F A;  4A3C D;  2CFP A;  4NEJ A;  2D9Q A;  3VA2 A;  4ZW9 A;  4IU8 A;  4JRE A;  4TPG A;  3EJJ A;  1Y6K L;  3D85 C;  5A2N A;  4YB9 D;  2LMS A;  5IP7 D;  1BCN A;  4LEP A;  4O9H A;  1ITM A;  1Z7C A;  4U4W A;  4A3K D;  1ITI A;  4FA8 E;  2D48 A;  1IK0 A;  1LQS L;  2OQP A;  2INT A;  4W6V A;  3HHC A;  1CSG A;  2VUM D;  4TPJ A;  1NBP A;  2R92 D;  1JLI A;  4D2C A;  4GRW A;  1CNT 1;  2Q7N B;  4APS A;  5D71 A;  5FUC A;  4Z5R D;  3N06 A;  1M4B A;  4A3J D;  2L3O A;  3BES L;  3NCB A;  2B91 A;  3DGC L;  3NCC A;  3BPN A;  3TGX B;  3HOX D;  4J4L C;  2Z3Q A;  1RFB A;  1RHG A;  3HOW D;  2B63 D;  4RS1 A;  1M47 A;  4O6K A;  2JA5 D;  2LAG A;  1Y6M L;  3FKI D;  4ZF7 A;  5L6Y C;  2PSM A;  5EQH A;  4NEM A;  4OAA A;  1KF9 A;  4A3L D;  3QWR B;  3UEZ E;  4NN5 A;  1M49 A;  1PW4 A;  3SE4 B;  2B8X A;  2B8Y A;  2Q14 A;  5D6K A;  1HUL A;  2XUT A;  4A3F D;  1IRL A;  5IYB D;  1V7M V;  4D2B A;  1CN4 C;  4QIQ A;  4Q65 A;  2R93 D;  1BBN A;  4A3I D;  3BPL A;  2JA6 D;  1IL6 A;  5A2O A;  1CD9 A;  3LB6 A;  3UX9 A;  5IYD D;  3UF2 A;  4NI9 A;  4I77 Z;  3I4N D;  2Q98 A;  4BBS D;  3MZG A;  1VLK A;  5LQB A;  5C7X A;  3O7Q A;  1ALU A;  3D87 A;  1BP3 A;  5C3E D;  4DKE A;  1HWH A;  3H0G D;  1PGR A;  4ZWB A;  3S9D A;  3WCY I;  5FHX A;  1GNC A;  1PW6 A;  3SE3 B;  1EKU A;  2XQB A;  5IYC D;  4NN7 A;  5D28 B;  1HIJ A;  1Y14 A;  4DKD A;  4IU9 A;  4A3G D;  4A3D D;  3PO3 D;  4GC0 A;  1F45 B;  4YPG C;  1N1F A;  4ZWC A;  5TS9 A;  2B5I A;  2ERJ D;  4GBY A;  4CNI C;  1HWG A;  1GA3 A;  2B90 A;  4NN6 A;  4MHL A;  5D22 A;  3LB6 B;  3PIW A;  1LKI A;  3HOZ D;  1D9G A;  1BGD A;  1HIK A;  3G6D A;  3OG6 A;  4BY7 D;  2B8Z A;  1PV7 A;  1YKB A;  1J7V L;  3HHR A;  1BGE A;  1ETE A; 
#chains in the Genus database with same CATH homology
 4IKX A;  4U4W A;  4Q65 A;  5C65 A;  4JA3 A;  2CFQ A;  4XNJ A;  4LDS A;  2Y5Y A;  4IU9 A;  5EQH A;  4U4V A;  5A2O A;  3O7P A;  4IKV A;  4GC0 A;  4ZYR A;  4ZW9 A;  4OAA A;  4IKY A;  4OH3 A;  4IU8 A;  4U4T A;  4J05 A;  4ZWC A;  5EQI A;  4W6V A;  5GXB A;  4UVM A;  4JRE A;  4JR9 A;  2V8N A;  4TPH A;  1PW4 A;  4TPG A;  4GBZ A;  4XNI A;  4IKZ A;  4TPJ A;  4GBY A;  4ZWB A;  5D6K A;  4YBQ A;  4IKW A;  4D2D A;  5A2N A;  5D59 A;  2XUT A;  4YB9 D;  1PV7 A;  4PYP A;  3WDO A;  4D2C A;  5EQG A;  5D58 A;  3O7Q A;  1PV6 A;  2CFP A;  4LEP A;  4QIQ A;  4APS A;  4D2B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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