4U4TA

Structure of a nitrate/nitrite antiporter nark in nitrate-bound inward-open state
Total Genus 185
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
185
sequence length
451
structure length
444
Chain Sequence
VITDWRPEDPAFWQQRGQRIASRNLWISVPCLLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGRRWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPKQKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWIWVPFLAIFTIAAWFGMNDLATQLPVLKRGHLWIMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGLLFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSDERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACVVITWAVYGRHSKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli str. k12 substr. mg1655
molecule keywords Nitrate/nitrite transporter NarK
total genus 185
structure length 444
sequence length 451
ec nomenclature
pdb deposition date 2014-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07690 MFS_1 Major Facilitator Superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4u4tA01
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4u4tA02
4IU9A 4TPHA 4U4WA 5D58A 5A2OA 4ZWBA 5EQGA 4YBQA 5D59A 4D2BA 4U4VA 4GBZA 4D2CA 4GBYA 4TPGA 4IKWA 4IKYA 2V8NA 4IKZA 2Y5YA 1PV6A 4TPJA 4LEPA 3O7QA 4ZW9A 5C65A 1PV7A 4D2DA 4LDSA 4Q65A 4OH3A 5A2NA 4GC0A 4PYPA 4QIQA 4IKVA 5D6KA 4XNIA 3WDOA 4ZYRA 5GXBA 4IU8A 2CFQA 4JR9A 4XNJA 4APSA 2CFPA 4YB9D 3O7PA 4W6VA 4IKXA 2XUTA 4OAAA 4JA3A 4U4TA 1PW4A 4UVMA 5EQIA 5EQHA 4J05A 4JREA 4ZWCA
chains in the Genus database with same CATH superfamily
1EMRA 1ETEA 2Q14A 3WCYI 2R93D 4YPGC 1RFBA 1IK0A 5IYDD 5D28B 3OQ3A 1PW6A 3O7PA 4ZF7A 1CNT1 1LK3A 1IL6A 1FG9A 3INKC 4A3ED 2JA7D 4WRLB 4DKCA 1EXZA 2CFQA 3QB1A 2KZ1A 1NBPA 3EJJA 3DLQI 1M4AA 1BGCA 1INRA 1HULA 2LMSA 2Y5YA 2ILKA 3S9DA 2INTA 4LDSA 5IP7D 1HGUA 1BP3A 2IL6A 2PSMA 3HOUD 2C35A 1Z92A 3B5KA 5KNHI 3D48P 3NCEA 1I1RB 1J7VL 4BBSD 4A3FD 5L6YC 3NPZA 5D70A 3HOYD 4GBZA 3BPNA 2V8NA 4IKZA 4TPJA 4A3GD 5C65A 1ILKA 1ALUA 4BBRD 3OG4A 3VA2A 5IYBD 2D9QA 1PY2A 4IKXA 1F6FA 4OAAA 3H3VE 1PW4A 3DI3A 1Y1WD 4X51A 5D58A 1CN4C 3NCFA 4U4VA 4A3ID 4A3MD 2ERJD 4IKYA 3I4MD 2Q7NB 4NI7A 1AXIA 4Q65A 4OH3A 1HWHA 1CYLA 4GC0A 5D6KA 3N0PA 1B5LA 1M47A 4W6VA 4UVMA 1HIJA 2VUMD 3QB7A 2D48A 5C3ED 1KF9A 4BY7D 1ITIA 4BXXD 3NCBA 2XQBA 2Q98A 4NEMA 1ITMA 1M4RA 1P9MB 4YUEC 1LQSL 5A2NA 3G9VB 1GA3A 1HIKA 4IU9A 3PIVA 2B91A 5C4XD 3LB6B 1WCMD 4Z5RD 3BESL 4J4LC 1PGRA 1PV6A 4IKVA 4ZYRA 1BUYA 1CD9A 3AYHA 3PIWA 4A3JD 3QT2C 2CYKA 4DKFA 1IJZA 3DGCL 1A22A 5D22A 3QWRB 5A2OA 3BPLA 4D2CA 1WU3I 2O6IA 4ZW9A 4FA8E 4ZS7A 4PYPA 4NI9A 3PO3D 2H24A 4YQXA 2O26A 4MHLA 2R7ZD 3DI2A 4GRWA 2R92D 3PO2D 3MZGA 2B8ZA 4YDYI 4TPGA 3HOWD 1EVSA 2JA6D 1PV7A 4D2DA 4GS7A 1AX8A 4PS4A 3WDOA 4DKDA 1Y6ML 2CFPA 3HMXB 1V7MV 1ITLA 4NN5A 1IARA 1JLIA 1QVNA 4NKQC 1M49A 1PVHB 4BY1D 5FUCA 5TS9A 1GNCA 3EW3A 3UF2A 5IP9D 3I4ND 3SE4B 5E4EA 5FHXA 1D9GA 1EERA 3H0GD 4YBQA 4LRLA 5C44D 1Y6NL 5IYCD 1Y6KL 3HOZD 4DKEA 1HUWA 1V7NV 3D85C 3UF5A 4NN6A 3G6DA 3TGXB 1Z7CA 1HWGA 1BGDA 4ZWCA 3BPOA 2LAGA 2L3YA 5C7XA 4RS1A 4NN7A 3HHCA 1BCNA 1M4CA 4XNIA 4A3LD 4XNJA 4U4TA 4JREA 1FYHA 4A3BD 2HYMB 4A3DD 3QAZA 5LQBA 1EKUA 3HOXD 1M48A 4A3CD 4O6KA 5GXBA 3N06A 1RW5A 4EXNA 3LB6A 5EQIA 4NEJA 5EQHA 4J05A 4TPHA 2O27A 3NCCA 4A3KD 4I77Z 5D59A 2B5IA 3SE3B 4GBYA 3L5WI 4CNIC 3Q1SI 4LEPA 3O7QA 1YKBA 5D71A 1BGEA 1Y1VD 1M4BA 1D9CA 1CSGA 3FKID 1F45B 1IRLA 1N1FA 3IRHA 4U4WA 1AU1A 1ITFA 3OG6A 4D2BA 2B8XA 2B8UA 4EXPA 1HZIA 1A7MA 1LKIA 5D72A 1Y14A 2OQPA 3HOVD 4JR9A 4DOHA 3DUHC 1BBNA 2JA5D 1RCBA 4O9HA 2L3OA 4ZWBA 5EQGA 1RHGA 3UX9A 4IKWA 5FLMD 2Z3RA 3HHRA 2JA8D 4QIQA 4IU8A 3L5XA 3UEZE 2E9WC 2GMFA 4APSA 2B90A 4YB9D 2XUTA 1VLKA 3D87A 4JA3A 4A93D 2B63D 1SCFA 2Z3QA 2B8YA
chains in the Genus database with same CATH topology
4IU9A 4TPHA 4U4WA 5D58A 5A2OA 4ZWBA 5EQGA 4YBQA 5D59A 4D2BA 4U4VA 4GBZA 4D2CA 4GBYA 4TPGA 4IKWA 4IKYA 2V8NA 4IKZA 2Y5YA 1PV6A 4TPJA 4LEPA 3O7QA 4ZW9A 5C65A 1PV7A 4D2DA 4LDSA 4Q65A 4OH3A 5A2NA 4GC0A 4PYPA 4QIQA 4IKVA 5D6KA 4XNIA 3WDOA 4ZYRA 5GXBA 4IU8A 2CFQA 4JR9A 4XNJA 4APSA 2CFPA 4YB9D 3O7PA 4W6VA 4IKXA 2XUTA 4OAAA 4JA3A 4U4TA 1PW4A 4UVMA 5EQIA 5EQHA 4J05A 4JREA 4ZWCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IU9 A;  4TPH A;  4U4W A;  5D58 A;  5A2O A;  4ZWB A;  5EQG A;  4YBQ A;  5D59 A;  4D2B A;  4U4V A;  4GBZ A;  4D2C A;  4GBY A;  4TPG A;  4IKW A;  4IKY A;  2V8N A;  4IKZ A;  2Y5Y A;  1PV6 A;  4TPJ A;  4LEP A;  3O7Q A;  4ZW9 A;  5C65 A;  1PV7 A;  4D2D A;  4LDS A;  4Q65 A;  4OH3 A;  5A2N A;  4GC0 A;  4PYP A;  4QIQ A;  4IKV A;  5D6K A;  4XNI A;  3WDO A;  4ZYR A;  5GXB A;  4IU8 A;  2CFQ A;  4JR9 A;  4XNJ A;  4APS A;  2CFP A;  4YB9 D;  3O7P A;  4W6V A;  4IKX A;  2XUT A;  4OAA A;  4JA3 A;  4U4T A;  1PW4 A;  4UVM A;  5EQI A;  5EQH A;  4J05 A;  4JRE A;  4ZWC A; 
#chains in the Genus database with same CATH topology
 1EMR A;  1ETE A;  2Q14 A;  3WCY I;  2R93 D;  4YPG C;  1RFB A;  1IK0 A;  5IYD D;  5D28 B;  3OQ3 A;  1PW6 A;  3O7P A;  4ZF7 A;  1CNT 1;  1LK3 A;  1IL6 A;  1FG9 A;  3INK C;  4A3E D;  2JA7 D;  4WRL B;  4DKC A;  1EXZ A;  2CFQ A;  3QB1 A;  2KZ1 A;  1NBP A;  3EJJ A;  3DLQ I;  1M4A A;  1BGC A;  1INR A;  1HUL A;  2LMS A;  2Y5Y A;  2ILK A;  3S9D A;  2INT A;  4LDS A;  5IP7 D;  1HGU A;  1BP3 A;  2IL6 A;  2PSM A;  3HOU D;  2C35 A;  1Z92 A;  3B5K A;  5KNH I;  3D48 P;  3NCE A;  1I1R B;  1J7V L;  4BBS D;  4A3F D;  5L6Y C;  3NPZ A;  5D70 A;  3HOY D;  4GBZ A;  3BPN A;  2V8N A;  4IKZ A;  4TPJ A;  4A3G D;  5C65 A;  1ILK A;  1ALU A;  4BBR D;  3OG4 A;  3VA2 A;  5IYB D;  2D9Q A;  1PY2 A;  4IKX A;  1F6F A;  4OAA A;  3H3V E;  1PW4 A;  3DI3 A;  1Y1W D;  4X51 A;  5D58 A;  1CN4 C;  3NCF A;  4U4V A;  4A3I D;  4A3M D;  2ERJ D;  4IKY A;  3I4M D;  2Q7N B;  4NI7 A;  1AXI A;  4Q65 A;  4OH3 A;  1HWH A;  1CYL A;  4GC0 A;  5D6K A;  3N0P A;  1B5L A;  1M47 A;  4W6V A;  4UVM A;  1HIJ A;  2VUM D;  3QB7 A;  2D48 A;  5C3E D;  1KF9 A;  4BY7 D;  1ITI A;  4BXX D;  3NCB A;  2XQB A;  2Q98 A;  4NEM A;  1ITM A;  1M4R A;  1P9M B;  4YUE C;  1LQS L;  5A2N A;  3G9V B;  1GA3 A;  1HIK A;  4IU9 A;  3PIV A;  2B91 A;  5C4X D;  3LB6 B;  1WCM D;  4Z5R D;  3BES L;  4J4L C;  1PGR A;  1PV6 A;  4IKV A;  4ZYR A;  1BUY A;  1CD9 A;  3AYH A;  3PIW A;  4A3J D;  3QT2 C;  2CYK A;  4DKF A;  1IJZ A;  3DGC L;  1A22 A;  5D22 A;  3QWR B;  5A2O A;  3BPL A;  4D2C A;  1WU3 I;  2O6I A;  4ZW9 A;  4FA8 E;  4ZS7 A;  4PYP A;  4NI9 A;  3PO3 D;  2H24 A;  4YQX A;  2O26 A;  4MHL A;  2R7Z D;  3DI2 A;  4GRW A;  2R92 D;  3PO2 D;  3MZG A;  2B8Z A;  4YDY I;  4TPG A;  3HOW D;  1EVS A;  2JA6 D;  1PV7 A;  4D2D A;  4GS7 A;  1AX8 A;  4PS4 A;  3WDO A;  4DKD A;  1Y6M L;  2CFP A;  3HMX B;  1V7M V;  1ITL A;  4NN5 A;  1IAR A;  1JLI A;  1QVN A;  4NKQ C;  1M49 A;  1PVH B;  4BY1 D;  5FUC A;  5TS9 A;  1GNC A;  3EW3 A;  3UF2 A;  5IP9 D;  3I4N D;  3SE4 B;  5E4E A;  5FHX A;  1D9G A;  1EER A;  3H0G D;  4YBQ A;  4LRL A;  5C44 D;  1Y6N L;  5IYC D;  1Y6K L;  3HOZ D;  4DKE A;  1HUW A;  1V7N V;  3D85 C;  3UF5 A;  4NN6 A;  3G6D A;  3TGX B;  1Z7C A;  1HWG A;  1BGD A;  4ZWC A;  3BPO A;  2LAG A;  2L3Y A;  5C7X A;  4RS1 A;  4NN7 A;  3HHC A;  1BCN A;  1M4C A;  4XNI A;  4A3L D;  4XNJ A;  4U4T A;  4JRE A;  1FYH A;  4A3B D;  2HYM B;  4A3D D;  3QAZ A;  5LQB A;  1EKU A;  3HOX D;  1M48 A;  4A3C D;  4O6K A;  5GXB A;  3N06 A;  1RW5 A;  4EXN A;  3LB6 A;  5EQI A;  4NEJ A;  5EQH A;  4J05 A;  4TPH A;  2O27 A;  3NCC A;  4A3K D;  4I77 Z;  5D59 A;  2B5I A;  3SE3 B;  4GBY A;  3L5W I;  4CNI C;  3Q1S I;  4LEP A;  3O7Q A;  1YKB A;  5D71 A;  1BGE A;  1Y1V D;  1M4B A;  1D9C A;  1CSG A;  3FKI D;  1F45 B;  1IRL A;  1N1F A;  3IRH A;  4U4W A;  1AU1 A;  1ITF A;  3OG6 A;  4D2B A;  2B8X A;  2B8U A;  4EXP A;  1HZI A;  1A7M A;  1LKI A;  5D72 A;  1Y14 A;  2OQP A;  3HOV D;  4JR9 A;  4DOH A;  3DUH C;  1BBN A;  2JA5 D;  1RCB A;  4O9H A;  2L3O A;  4ZWB A;  5EQG A;  1RHG A;  3UX9 A;  4IKW A;  5FLM D;  2Z3R A;  3HHR A;  2JA8 D;  4QIQ A;  4IU8 A;  3L5X A;  3UEZ E;  2E9W C;  2GMF A;  4APS A;  2B90 A;  4YB9 D;  2XUT A;  1VLK A;  3D87 A;  4JA3 A;  4A93 D;  2B63 D;  1SCF A;  2Z3Q A;  2B8Y A; 
#chains in the Genus database with same CATH homology
 4IU9 A;  4TPH A;  4U4W A;  5D58 A;  5A2O A;  4ZWB A;  5EQG A;  4YBQ A;  5D59 A;  4D2B A;  4U4V A;  4GBZ A;  4D2C A;  4GBY A;  4TPG A;  4IKW A;  4IKY A;  2V8N A;  4IKZ A;  2Y5Y A;  1PV6 A;  4TPJ A;  4LEP A;  3O7Q A;  4ZW9 A;  5C65 A;  1PV7 A;  4D2D A;  4LDS A;  4Q65 A;  4OH3 A;  5A2N A;  4GC0 A;  4PYP A;  4QIQ A;  4IKV A;  5D6K A;  4XNI A;  3WDO A;  4ZYR A;  5GXB A;  4IU8 A;  2CFQ A;  4JR9 A;  4XNJ A;  4APS A;  2CFP A;  4YB9 D;  3O7P A;  4W6V A;  4IKX A;  2XUT A;  4OAA A;  4JA3 A;  4U4T A;  1PW4 A;  4UVM A;  5EQI A;  5EQH A;  4J05 A;  4JRE A;  4ZWC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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