4U4VA

Structure of a nitrate/nitrite antiporter nark in apo inward-open state
Total Genus 180
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
180
sequence length
451
structure length
442
Chain Sequence
AVITDWRPEDPAFWQQRGQRIASRNLWISVPCLLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGRRWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPKQKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWIWVPFLAIFTIAAWFGMNDLATLPVLKRGHLWIMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGLLFLTLPTDQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSDERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACVVITWAVYGRHSKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK
pubmed doi rcsb
molecule tags Transport protein
source organism Escherichia coli str. k-12 substr. mg1655
molecule keywords Nitrate/nitrite transporter NarK
total genus 180
structure length 442
sequence length 451
ec nomenclature
pdb deposition date 2014-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07690 MFS_1 Major Facilitator Superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4u4vA01
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4u4vA02
4GBYA 4XNIA 4ZWBA 4YB9D 4TPGA 4D2DA 5C65A 2XUTA 4OH3A 4TPHA 1PV6A 2V8NA 3O7QA 4IKXA 4IKYA 4LEPA 4ZWCA 4YBQA 5A2OA 4XNJA 4IKVA 4JREA 4Q65A 4IKWA 4QIQA 5A2NA 4IU8A 4APSA 4TPJA 4IKZA 5D58A 5EQGA 4U4WA 4OAAA 1PW4A 5GXBA 4PYPA 5EQHA 4D2CA 4JR9A 4LDSA 2Y5YA 3WDOA 4ZYRA 5D59A 1PV7A 3O7PA 4U4VA 4UVMA 4J05A 4U4TA 4W6VA 5EQIA 4JA3A 5D6KA 2CFPA 4GC0A 4IU9A 4ZW9A 2CFQA 4D2BA 4GBZA
chains in the Genus database with same CATH superfamily
4YB9D 1RHGA 1B5LA 4OH3A 1IRLA 1M47A 3O7QA 1V7MV 5IYDD 4NEMA 4U4WA 3I4ND 1BCNA 3HHCA 1FG9A 4A93D 3O7PA 1CD9A 1ITFA 2ERJD 1PGRA 4GBYA 1ITMA 3LB6B 5FLMD 5EQHA 4D2CA 3LB6A 1IL6A 3QWRB 1HZIA 2JA6D 1RCBA 1BBNA 4W6VA 3DI2A 2JA8D 4NN7A 1GA3A 1IK0A 1JLIA 4DOHA 3QT2C 3EJJA 3UF5A 5A2NA 2GMFA 5D58A 2XQBA 5D28B 1F6FA 1HWHA 3S9DA 2L3OA 3HHRA 5D59A 1PV7A 2R93D 3SE4B 3BPNA 4LRLA 4WRLB 2CFPA 4NEJA 1VLKA 3WCYI 3I4MD 2E9WC 3PO2D 5C3ED 2R92D 3TGXB 4DKDA 2B5IA 4JA3A 5LQBA 2OQPA 4BY7D 1Z7CA 4ZWBA 4TPGA 1ITLA 4LEPA 1GNCA 5E4EA 4IKWA 2D48A 4OAAA 1HUWA 1D9CA 1ITIA 3HOXD 1AXIA 3N06A 1CN4C 3PIWA 4ZS7A 1QVNA 4NI7A 3G9VB 1LK3A 1M48A 2O26A 4ZW9A 2B8YA 4O6KA 3SE3B 3L5XA 5A2OA 2O6IA 4XNJA 1WU3I 4BY1D 1ETEA 5EQGA 2B91A 2CYKA 1EVSA 1P9MB 3QAZA 1J7VL 4U4VA 3UX9A 3VA2A 1M4BA 1A22A 4A3MD 4IU9A 4O9HA 5D70A 3DUHC 3Q1SI 1HGUA 4YBQA 1Y6KL 1F45B 4A3FD 1M49A 4GS7A 1KF9A 4ZYRA 4PS4A 2H24A 4U4TA 4J4LC 3BPOA 1LQSL 1EXZA 1Y6ML 4YDYI 4BXXD 5C44D 3FKID 1CSGA 5IYBD 1EKUA 2O27A 2JA5D 3HOZD 4A3GD 2Q98A 1INRA 1I1RB 1CNT1 3N0PA 4A3CD 4DKFA 1YKBA 2B8UA 3EW3A 3HOVD 1PV6A 1HULA 4YUEC 5TS9A 5C4XD 4EXNA 4I77Z 5IP7D 1FYHA 2IL6A 4LDSA 5FHXA 2ILKA 1PY2A 4A3LD 2HYMB 3OG4A 4DKCA 4D2BA 5GXBA 4TPHA 1M4RA 2C35A 1BP3A 1Y1VD 1ALUA 4BBSD 1SCFA 3H0GD 2XUTA 3MZGA 3PO3D 1LKIA 1BGEA 4A3DD 1PW6A 5L6YC 4JREA 1PVHB 2Q7NB 1Z92A 4NKQC 1Y14A 3DGCL 2Y5YA 1IJZA 3NCBA 5KNHI 1M4CA 1RW5A 4D2DA 1CYLA 4YQXA 3D87A 5C65A 5IP9D 4IKVA 3HMXB 3DLQI 1HIJA 1EMRA 4MHLA 4RS1A 1AU1A 4A3JD 4A3BD 1A7MA 5IYCD 4NI9A 3NCFA 4EXPA 2B8ZA 5D22A 2Z3RA 4ZWCA 4IKXA 2B63D 2JA7D 4APSA 1EERA 1BUYA 1V7NV 2KZ1A 1AX8A 3D48P 2Q14A 5EQIA 1BGDA 2R7ZD 4BBRD 3HOWD 2LMSA 4CNIC 3PIVA 1M4AA 3UEZE 4A3ED 1IARA 4DKEA 2B8XA 4NN6A 3QB7A 1HWGA 4J05A 2VUMD 2INTA 5D6KA 4X51A 5C7XA 3D85C 3B5KA 2V8NA 3L5WI 1D9GA 1WCMD 4TPJA 3OG6A 4IKZA 3BESL 2Z3QA 4PYPA 3INKC 4JR9A 5FUCA 3DI3A 5D72A 3NCEA 4UVMA 3NPZA 1NBPA 3QB1A 3UF2A 4XNIA 3H3VE 4YPGC 1ILKA 4QIQA 1Y6NL 4IU8A 1HIKA 3AYHA 4A3KD 5D71A 2D9QA 3HOYD 1Y1WD 3NCCA 1BGCA 4NN5A 2L3YA 3IRHA 4FA8E 4GBZA 2PSMA 3BPLA 4A3ID 3HOUD 4IKYA 4Q65A 2LAGA 1PW4A 4Z5RD 3G6DA 1RFBA 3WDOA 1N1FA 4ZF7A 4GRWA 4GC0A 2B90A 2CFQA 3OQ3A
chains in the Genus database with same CATH topology
4GBYA 4XNIA 4ZWBA 4YB9D 4TPGA 4D2DA 5C65A 2XUTA 4OH3A 4TPHA 1PV6A 2V8NA 3O7QA 4IKXA 4IKYA 4LEPA 4ZWCA 4YBQA 5A2OA 4XNJA 4IKVA 4JREA 4Q65A 4IKWA 4QIQA 5A2NA 4IU8A 4APSA 4TPJA 4IKZA 5D58A 5EQGA 4U4WA 4OAAA 1PW4A 5GXBA 4PYPA 5EQHA 4D2CA 4JR9A 4LDSA 2Y5YA 3WDOA 4ZYRA 5D59A 1PV7A 3O7PA 4U4VA 4UVMA 4J05A 4U4TA 4W6VA 5EQIA 4JA3A 5D6KA 2CFPA 4GC0A 4IU9A 4ZW9A 2CFQA 4D2BA 4GBZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GBY A;  4XNI A;  4ZWB A;  4YB9 D;  4TPG A;  4D2D A;  5C65 A;  2XUT A;  4OH3 A;  4TPH A;  1PV6 A;  2V8N A;  3O7Q A;  4IKX A;  4IKY A;  4LEP A;  4ZWC A;  4YBQ A;  5A2O A;  4XNJ A;  4IKV A;  4JRE A;  4Q65 A;  4IKW A;  4QIQ A;  5A2N A;  4IU8 A;  4APS A;  4TPJ A;  4IKZ A;  5D58 A;  5EQG A;  4U4W A;  4OAA A;  1PW4 A;  5GXB A;  4PYP A;  5EQH A;  4D2C A;  4JR9 A;  4LDS A;  2Y5Y A;  3WDO A;  4ZYR A;  5D59 A;  1PV7 A;  3O7P A;  4U4V A;  4UVM A;  4J05 A;  4U4T A;  4W6V A;  5EQI A;  4JA3 A;  5D6K A;  2CFP A;  4GC0 A;  4IU9 A;  4ZW9 A;  2CFQ A;  4D2B A;  4GBZ A; 
#chains in the Genus database with same CATH topology
 4YB9 D;  1RHG A;  1B5L A;  4OH3 A;  1IRL A;  1M47 A;  3O7Q A;  1V7M V;  5IYD D;  4NEM A;  4U4W A;  3I4N D;  1BCN A;  3HHC A;  1FG9 A;  4A93 D;  3O7P A;  1CD9 A;  1ITF A;  2ERJ D;  1PGR A;  4GBY A;  1ITM A;  3LB6 B;  5FLM D;  5EQH A;  4D2C A;  3LB6 A;  1IL6 A;  3QWR B;  1HZI A;  2JA6 D;  1RCB A;  1BBN A;  4W6V A;  3DI2 A;  2JA8 D;  4NN7 A;  1GA3 A;  1IK0 A;  1JLI A;  4DOH A;  3QT2 C;  3EJJ A;  3UF5 A;  5A2N A;  2GMF A;  5D58 A;  2XQB A;  5D28 B;  1F6F A;  1HWH A;  3S9D A;  2L3O A;  3HHR A;  5D59 A;  1PV7 A;  2R93 D;  3SE4 B;  3BPN A;  4LRL A;  4WRL B;  2CFP A;  4NEJ A;  1VLK A;  3WCY I;  3I4M D;  2E9W C;  3PO2 D;  5C3E D;  2R92 D;  3TGX B;  4DKD A;  2B5I A;  4JA3 A;  5LQB A;  2OQP A;  4BY7 D;  1Z7C A;  4ZWB A;  4TPG A;  1ITL A;  4LEP A;  1GNC A;  5E4E A;  4IKW A;  2D48 A;  4OAA A;  1HUW A;  1D9C A;  1ITI A;  3HOX D;  1AXI A;  3N06 A;  1CN4 C;  3PIW A;  4ZS7 A;  1QVN A;  4NI7 A;  3G9V B;  1LK3 A;  1M48 A;  2O26 A;  4ZW9 A;  2B8Y A;  4O6K A;  3SE3 B;  3L5X A;  5A2O A;  2O6I A;  4XNJ A;  1WU3 I;  4BY1 D;  1ETE A;  5EQG A;  2B91 A;  2CYK A;  1EVS A;  1P9M B;  3QAZ A;  1J7V L;  4U4V A;  3UX9 A;  3VA2 A;  1M4B A;  1A22 A;  4A3M D;  4IU9 A;  4O9H A;  5D70 A;  3DUH C;  3Q1S I;  1HGU A;  4YBQ A;  1Y6K L;  1F45 B;  4A3F D;  1M49 A;  4GS7 A;  1KF9 A;  4ZYR A;  4PS4 A;  2H24 A;  4U4T A;  4J4L C;  3BPO A;  1LQS L;  1EXZ A;  1Y6M L;  4YDY I;  4BXX D;  5C44 D;  3FKI D;  1CSG A;  5IYB D;  1EKU A;  2O27 A;  2JA5 D;  3HOZ D;  4A3G D;  2Q98 A;  1INR A;  1I1R B;  1CNT 1;  3N0P A;  4A3C D;  4DKF A;  1YKB A;  2B8U A;  3EW3 A;  3HOV D;  1PV6 A;  1HUL A;  4YUE C;  5TS9 A;  5C4X D;  4EXN A;  4I77 Z;  5IP7 D;  1FYH A;  2IL6 A;  4LDS A;  5FHX A;  2ILK A;  1PY2 A;  4A3L D;  2HYM B;  3OG4 A;  4DKC A;  4D2B A;  5GXB A;  4TPH A;  1M4R A;  2C35 A;  1BP3 A;  1Y1V D;  1ALU A;  4BBS D;  1SCF A;  3H0G D;  2XUT A;  3MZG A;  3PO3 D;  1LKI A;  1BGE A;  4A3D D;  1PW6 A;  5L6Y C;  4JRE A;  1PVH B;  2Q7N B;  1Z92 A;  4NKQ C;  1Y14 A;  3DGC L;  2Y5Y A;  1IJZ A;  3NCB A;  5KNH I;  1M4C A;  1RW5 A;  4D2D A;  1CYL A;  4YQX A;  3D87 A;  5C65 A;  5IP9 D;  4IKV A;  3HMX B;  3DLQ I;  1HIJ A;  1EMR A;  4MHL A;  4RS1 A;  1AU1 A;  4A3J D;  4A3B D;  1A7M A;  5IYC D;  4NI9 A;  3NCF A;  4EXP A;  2B8Z A;  5D22 A;  2Z3R A;  4ZWC A;  4IKX A;  2B63 D;  2JA7 D;  4APS A;  1EER A;  1BUY A;  1V7N V;  2KZ1 A;  1AX8 A;  3D48 P;  2Q14 A;  5EQI A;  1BGD A;  2R7Z D;  4BBR D;  3HOW D;  2LMS A;  4CNI C;  3PIV A;  1M4A A;  3UEZ E;  4A3E D;  1IAR A;  4DKE A;  2B8X A;  4NN6 A;  3QB7 A;  1HWG A;  4J05 A;  2VUM D;  2INT A;  5D6K A;  4X51 A;  5C7X A;  3D85 C;  3B5K A;  2V8N A;  3L5W I;  1D9G A;  1WCM D;  4TPJ A;  3OG6 A;  4IKZ A;  3BES L;  2Z3Q A;  4PYP A;  3INK C;  4JR9 A;  5FUC A;  3DI3 A;  5D72 A;  3NCE A;  4UVM A;  3NPZ A;  1NBP A;  3QB1 A;  3UF2 A;  4XNI A;  3H3V E;  4YPG C;  1ILK A;  4QIQ A;  1Y6N L;  4IU8 A;  1HIK A;  3AYH A;  4A3K D;  5D71 A;  2D9Q A;  3HOY D;  1Y1W D;  3NCC A;  1BGC A;  4NN5 A;  2L3Y A;  3IRH A;  4FA8 E;  4GBZ A;  2PSM A;  3BPL A;  4A3I D;  3HOU D;  4IKY A;  4Q65 A;  2LAG A;  1PW4 A;  4Z5R D;  3G6D A;  1RFB A;  3WDO A;  1N1F A;  4ZF7 A;  4GRW A;  4GC0 A;  2B90 A;  2CFQ A;  3OQ3 A; 
#chains in the Genus database with same CATH homology
 4GBY A;  4XNI A;  4ZWB A;  4YB9 D;  4TPG A;  4D2D A;  5C65 A;  2XUT A;  4OH3 A;  4TPH A;  1PV6 A;  2V8N A;  3O7Q A;  4IKX A;  4IKY A;  4LEP A;  4ZWC A;  4YBQ A;  5A2O A;  4XNJ A;  4IKV A;  4JRE A;  4Q65 A;  4IKW A;  4QIQ A;  5A2N A;  4IU8 A;  4APS A;  4TPJ A;  4IKZ A;  5D58 A;  5EQG A;  4U4W A;  4OAA A;  1PW4 A;  5GXB A;  4PYP A;  5EQH A;  4D2C A;  4JR9 A;  4LDS A;  2Y5Y A;  3WDO A;  4ZYR A;  5D59 A;  1PV7 A;  3O7P A;  4U4V A;  4UVM A;  4J05 A;  4U4T A;  4W6V A;  5EQI A;  4JA3 A;  5D6K A;  2CFP A;  4GC0 A;  4IU9 A;  4ZW9 A;  2CFQ A;  4D2B A;  4GBZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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