4ZW9A

Crystal structure of human glut3 bound to d-glucose in the outward-occluded conformation at 1.5 angstrom
Total Genus 224
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
470
structure length
470
Chain Sequence
MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFITKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of ligand recognition and transport by glucose transporters
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords Solute carrier family 2, facilitated glucose transporter mem
total genus 224
structure length 470
sequence length 470
ec nomenclature
pdb deposition date 2015-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00083 Sugar_tr Sugar (and other) transporter
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4zw9A00
2CFQA 5A2NA 4W6VA 4GC0A 4J05A 4IKYA 4IKXA 4UVMA 5EQIA 1PV7A 4OAAA 4U4VA 4U4WA 5D6KA 4ZW9A 5C65A 4ZWCA 2V8NA 3WDOA 4GBZA 4IKZA 4XNJA 2CFPA 3O7QA 4JR9A 4Q65A 4GBYA 4ZWBA 4IKWA 4JREA 4D2BA 5D58A 1PW4A 4IU9A 4QIQA 4XNIA 4U4TA 4D2CA 4LEPA 5EQGA 5GXBA 5D59A 4TPGA 5A2OA 4LDSA 4TPHA 4D2DA 4TPJA 1PV6A 4OH3A 2Y5YA 4IKVA 2XUTA 3O7PA 4IU8A 4JA3A 4PYPA 4YBQA 4YB9D 5EQHA 4APSA 4ZYRA
chains in the Genus database with same CATH superfamily
1HWHA 1Y1WD 1D9CA 4GC0A 4X51A 5EQIA 3PIWA 2H24A 3HHCA 3G9VB 1PY2A 2LMSA 2PSMA 2Q98A 3HOZD 2B63D 4FA8E 3N0PA 5EQGA 3EW3A 4TPHA 1IARA 3L5XA 3DI2A 4A3ID 1PW6A 1M49A 1IL6A 5FHXA 1WCMD 3MZGA 5D70A 1QVNA 4U4TA 4BBRD 5FUCA 1EKUA 3TGXB 1V7NV 4J05A 3QB7A 1BGCA 2JA5D 1PGRA 4U4WA 4Z5RD 5D28B 2CFPA 2B8YA 4EXPA 2D9QA 3HOXD 3Q1SI 4D2DA 4IKVA 4JA3A 4NN7A 2C35A 3DUHC 3HOUD 1LK3A 3BESL 2O27A 4CNIC 4LRLA 4EXNA 4IKZA 4ZWBA 4IKWA 2IL6A 1Z92A 3VA2A 1IK0A 3EJJA 4QIQA 3PO3D 3UF2A 3N06A 4O6KA 4TPJA 3NCEA 1RCBA 1ITIA 1RW5A 2E9WC 1PV7A 4ZS7A 1JLIA 3HOYD 2V8NA 3QAZA 2OQPA 4NN6A 1RHGA 3OQ3A 2INTA 3H0GD 1FYHA 5E4EA 1ITMA 4ZF7A 1LKIA 2XUTA 2JA6D 5EQHA 4ZYRA 1AU1A 5A2NA 1HIKA 1WU3I 4IKYA 4DKFA 4A3DD 1INRA 5D6KA 3QT2C 2Z3RA 4NEMA 2D48A 2Q7NB 4JREA 3NCBA 1M4AA 3OG4A 4DOHA 3BPLA 4YUEC 4YB9D 4PYPA 1IJZA 1BGDA 5IYBD 1M48A 2B8XA 4IKXA 1HIJA 2KZ1A 4I77Z 4MHLA 1B5LA 2O6IA 4Q65A 1KF9A 4GBYA 4YQXA 4O9HA 4NKQC 1Y6NL 5D58A 4D2CA 2B5IA 3DGCL 5D59A 4GRWA 1BP3A 2LAGA 5D71A 4UVMA 3OG6A 5KNHI 1M4RA 1BGEA 3FKID 4NI9A 1N1FA 4DKEA 3UEZE 5LQBA 2R7ZD 3D87A 4YDYI 2CFQA 3LB6B 1F45B 5IP9D 4W6VA 1M4CA 3IRHA 3QB1A 4A3JD 1AXIA 1GA3A 4A3FD 1BCNA 3QWRB 3I4ND 1NBPA 3G6DA 4NI7A 1M4BA 1VLKA 4DKDA 3D48P 3WCYI 4A3ED 2ERJD 4YPGC 1ITLA 3UF5A 3DLQI 5C65A 4ZW9A 4NEJA 5C44D 4LEPA 1Y1VD 4RS1A 1PV6A 1PVHB 1EVSA 3HMXB 1Y6ML 3D85C 2ILKA 4GS7A 1HULA 2JA8D 1CD9A 5IYDD 4OAAA 4U4VA 1I1RB 2L3OA 4BBSD 4JR9A 4A3BD 3I4MD 4A3KD 5GXBA 3DI3A 5A2OA 2GMFA 3O7PA 4IU8A 4APSA 4A93D 3SE3B 1F6FA 5IP7D 4PS4A 3BPOA 3WDOA 5D72A 5L6YC 1ITFA 4D2BA 5D22A 3B5KA 2XQBA 4NN5A 3NCFA 1ETEA 5TS9A 1J7VL 2Y5YA 4BXXD 3PO2D 1CNT1 1CSGA 4BY1D 3L5WI 1EMRA 4A3CD 1IRLA 3HHRA 1YKBA 4ZWCA 2B91A 1P9MB 3INKC 1EERA 2O26A 4GBZA 1AX8A 4A3LD 2Z3QA 4LDSA 4BY7D 1BBNA 1CYLA 3H3VE 4A3GD 1M47A 3NCCA 3LB6A 2CYKA 3PIVA 1SCFA 2JA7D 1ILKA 4XNJA 3O7QA 2R92D 3NPZA 5C3ED 1EXZA 1PW4A 5C4XD 2B8ZA 2B8UA 4TPGA 1LQSL 1RFBA 5C7XA 4YBQA 3HOWD 2HYMB 1HGUA 1GNCA 1HWGA 2VUMD 1HUWA 1Z7CA 1A7MA 2Q14A 1BUYA 4J4LC 2B90A 1V7MV 4IU9A 4XNIA 4A3MD 3HOVD 2R93D 1ALUA 2L3YA 1FG9A 3BPNA 1D9GA 3SE4B 3S9DA 5IYCD 1Y14A 5FLMD 3UX9A 1Y6KL 4DKCA 3AYHA 1A22A 4WRLB 4OH3A 1CN4C 1HZIA
chains in the Genus database with same CATH topology
2CFQA 5A2NA 4W6VA 4GC0A 4J05A 4IKYA 4IKXA 4UVMA 5EQIA 1PV7A 4OAAA 4U4VA 4U4WA 5D6KA 4ZW9A 5C65A 4ZWCA 2V8NA 3WDOA 4GBZA 4IKZA 4XNJA 2CFPA 3O7QA 4JR9A 4Q65A 4GBYA 4ZWBA 4IKWA 4JREA 4D2BA 5D58A 1PW4A 4IU9A 4QIQA 4XNIA 4U4TA 4D2CA 4LEPA 5EQGA 5GXBA 5D59A 4TPGA 5A2OA 4LDSA 4TPHA 4D2DA 4TPJA 1PV6A 4OH3A 2Y5YA 4IKVA 2XUTA 3O7PA 4IU8A 4JA3A 4PYPA 4YBQA 4YB9D 5EQHA 4APSA 4ZYRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CFQ A;  5A2N A;  4W6V A;  4GC0 A;  4J05 A;  4IKY A;  4IKX A;  4UVM A;  5EQI A;  1PV7 A;  4OAA A;  4U4V A;  4U4W A;  5D6K A;  4ZW9 A;  5C65 A;  4ZWC A;  2V8N A;  3WDO A;  4GBZ A;  4IKZ A;  4XNJ A;  2CFP A;  3O7Q A;  4JR9 A;  4Q65 A;  4GBY A;  4ZWB A;  4IKW A;  4JRE A;  4D2B A;  5D58 A;  1PW4 A;  4IU9 A;  4QIQ A;  4XNI A;  4U4T A;  4D2C A;  4LEP A;  5EQG A;  5GXB A;  5D59 A;  4TPG A;  5A2O A;  4LDS A;  4TPH A;  4D2D A;  4TPJ A;  1PV6 A;  4OH3 A;  2Y5Y A;  4IKV A;  2XUT A;  3O7P A;  4IU8 A;  4JA3 A;  4PYP A;  4YBQ A;  4YB9 D;  5EQH A;  4APS A;  4ZYR A; 
#chains in the Genus database with same CATH topology
 1HWH A;  1Y1W D;  1D9C A;  4GC0 A;  4X51 A;  5EQI A;  3PIW A;  2H24 A;  3HHC A;  3G9V B;  1PY2 A;  2LMS A;  2PSM A;  2Q98 A;  3HOZ D;  2B63 D;  4FA8 E;  3N0P A;  5EQG A;  3EW3 A;  4TPH A;  1IAR A;  3L5X A;  3DI2 A;  4A3I D;  1PW6 A;  1M49 A;  1IL6 A;  5FHX A;  1WCM D;  3MZG A;  5D70 A;  1QVN A;  4U4T A;  4BBR D;  5FUC A;  1EKU A;  3TGX B;  1V7N V;  4J05 A;  3QB7 A;  1BGC A;  2JA5 D;  1PGR A;  4U4W A;  4Z5R D;  5D28 B;  2CFP A;  2B8Y A;  4EXP A;  2D9Q A;  3HOX D;  3Q1S I;  4D2D A;  4IKV A;  4JA3 A;  4NN7 A;  2C35 A;  3DUH C;  3HOU D;  1LK3 A;  3BES L;  2O27 A;  4CNI C;  4LRL A;  4EXN A;  4IKZ A;  4ZWB A;  4IKW A;  2IL6 A;  1Z92 A;  3VA2 A;  1IK0 A;  3EJJ A;  4QIQ A;  3PO3 D;  3UF2 A;  3N06 A;  4O6K A;  4TPJ A;  3NCE A;  1RCB A;  1ITI A;  1RW5 A;  2E9W C;  1PV7 A;  4ZS7 A;  1JLI A;  3HOY D;  2V8N A;  3QAZ A;  2OQP A;  4NN6 A;  1RHG A;  3OQ3 A;  2INT A;  3H0G D;  1FYH A;  5E4E A;  1ITM A;  4ZF7 A;  1LKI A;  2XUT A;  2JA6 D;  5EQH A;  4ZYR A;  1AU1 A;  5A2N A;  1HIK A;  1WU3 I;  4IKY A;  4DKF A;  4A3D D;  1INR A;  5D6K A;  3QT2 C;  2Z3R A;  4NEM A;  2D48 A;  2Q7N B;  4JRE A;  3NCB A;  1M4A A;  3OG4 A;  4DOH A;  3BPL A;  4YUE C;  4YB9 D;  4PYP A;  1IJZ A;  1BGD A;  5IYB D;  1M48 A;  2B8X A;  4IKX A;  1HIJ A;  2KZ1 A;  4I77 Z;  4MHL A;  1B5L A;  2O6I A;  4Q65 A;  1KF9 A;  4GBY A;  4YQX A;  4O9H A;  4NKQ C;  1Y6N L;  5D58 A;  4D2C A;  2B5I A;  3DGC L;  5D59 A;  4GRW A;  1BP3 A;  2LAG A;  5D71 A;  4UVM A;  3OG6 A;  5KNH I;  1M4R A;  1BGE A;  3FKI D;  4NI9 A;  1N1F A;  4DKE A;  3UEZ E;  5LQB A;  2R7Z D;  3D87 A;  4YDY I;  2CFQ A;  3LB6 B;  1F45 B;  5IP9 D;  4W6V A;  1M4C A;  3IRH A;  3QB1 A;  4A3J D;  1AXI A;  1GA3 A;  4A3F D;  1BCN A;  3QWR B;  3I4N D;  1NBP A;  3G6D A;  4NI7 A;  1M4B A;  1VLK A;  4DKD A;  3D48 P;  3WCY I;  4A3E D;  2ERJ D;  4YPG C;  1ITL A;  3UF5 A;  3DLQ I;  5C65 A;  4ZW9 A;  4NEJ A;  5C44 D;  4LEP A;  1Y1V D;  4RS1 A;  1PV6 A;  1PVH B;  1EVS A;  3HMX B;  1Y6M L;  3D85 C;  2ILK A;  4GS7 A;  1HUL A;  2JA8 D;  1CD9 A;  5IYD D;  4OAA A;  4U4V A;  1I1R B;  2L3O A;  4BBS D;  4JR9 A;  4A3B D;  3I4M D;  4A3K D;  5GXB A;  3DI3 A;  5A2O A;  2GMF A;  3O7P A;  4IU8 A;  4APS A;  4A93 D;  3SE3 B;  1F6F A;  5IP7 D;  4PS4 A;  3BPO A;  3WDO A;  5D72 A;  5L6Y C;  1ITF A;  4D2B A;  5D22 A;  3B5K A;  2XQB A;  4NN5 A;  3NCF A;  1ETE A;  5TS9 A;  1J7V L;  2Y5Y A;  4BXX D;  3PO2 D;  1CNT 1;  1CSG A;  4BY1 D;  3L5W I;  1EMR A;  4A3C D;  1IRL A;  3HHR A;  1YKB A;  4ZWC A;  2B91 A;  1P9M B;  3INK C;  1EER A;  2O26 A;  4GBZ A;  1AX8 A;  4A3L D;  2Z3Q A;  4LDS A;  4BY7 D;  1BBN A;  1CYL A;  3H3V E;  4A3G D;  1M47 A;  3NCC A;  3LB6 A;  2CYK A;  3PIV A;  1SCF A;  2JA7 D;  1ILK A;  4XNJ A;  3O7Q A;  2R92 D;  3NPZ A;  5C3E D;  1EXZ A;  1PW4 A;  5C4X D;  2B8Z A;  2B8U A;  4TPG A;  1LQS L;  1RFB A;  5C7X A;  4YBQ A;  3HOW D;  2HYM B;  1HGU A;  1GNC A;  1HWG A;  2VUM D;  1HUW A;  1Z7C A;  1A7M A;  2Q14 A;  1BUY A;  4J4L C;  2B90 A;  1V7M V;  4IU9 A;  4XNI A;  4A3M D;  3HOV D;  2R93 D;  1ALU A;  2L3Y A;  1FG9 A;  3BPN A;  1D9G A;  3SE4 B;  3S9D A;  5IYC D;  1Y14 A;  5FLM D;  3UX9 A;  1Y6K L;  4DKC A;  3AYH A;  1A22 A;  4WRL B;  4OH3 A;  1CN4 C;  1HZI A; 
#chains in the Genus database with same CATH homology
 2CFQ A;  5A2N A;  4W6V A;  4GC0 A;  4J05 A;  4IKY A;  4IKX A;  4UVM A;  5EQI A;  1PV7 A;  4OAA A;  4U4V A;  4U4W A;  5D6K A;  4ZW9 A;  5C65 A;  4ZWC A;  2V8N A;  3WDO A;  4GBZ A;  4IKZ A;  4XNJ A;  2CFP A;  3O7Q A;  4JR9 A;  4Q65 A;  4GBY A;  4ZWB A;  4IKW A;  4JRE A;  4D2B A;  5D58 A;  1PW4 A;  4IU9 A;  4QIQ A;  4XNI A;  4U4T A;  4D2C A;  4LEP A;  5EQG A;  5GXB A;  5D59 A;  4TPG A;  5A2O A;  4LDS A;  4TPH A;  4D2D A;  4TPJ A;  1PV6 A;  4OH3 A;  2Y5Y A;  4IKV A;  2XUT A;  3O7P A;  4IU8 A;  4JA3 A;  4PYP A;  4YBQ A;  4YB9 D;  5EQH A;  4APS A;  4ZYR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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