5FLMD

Structure of transcribing mammalian rna polymerase ii
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
128
structure length
128
Chain Sequence
EEDASQLIFPKEFETAETLLNSEVHMLLEHRKQQNESAEDEQELSEVFMKTLNYTARFSRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGRFEDEELQQILDDIQTKRSFQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Transcribing Mammalian RNA Polymerase II
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE
total genus 43
structure length 128
sequence length 128
ec nomenclature
pdb deposition date 2015-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 5flmD00
2JA7D 4BXXD 2R93D 4A3KD 2VUMD 2JA5D 4BBSD 3I4ND 2JA8D 4A3GD 3PO2D 5C4XD 5C44D 5IYBD 3AYHA 5IYDD 5IYCD 2C35A 3I4MD 5FLMD 3H3VE 4A3ID 4A3FD 2JA6D 4A3ED 3HOWD 4BY1D 3H0GD 4A3DD 3PO3D 5IP7D 4A3BD 1Y1VD 3FKID 1Y1WD 3HOYD 3HOUD 1Y14A 3HOZD 5C3ED 2R7ZD 4BY7D 5IP9D 2R92D 3HOXD 3HOVD 1WCMD 4BBRD 4A3CD 2B63D 4A93D 4A3LD 4A3MD 4A3JD
chains in the Genus database with same CATH superfamily
4TPJA 4YQXA 3L5WI 1ITIA 2JA5D 2CYKA 3S9DA 2GMFA 3NCFA 5FLMD 1M49A 3DGCL 5GXBA 3G6DA 4U4TA 3G9VB 3HOZD 3EW3A 4LEPA 2R92D 1IRLA 4ZW9A 1HUWA 1ITLA 4RS1A 3OQ3A 4YDYI 3DI3A 1N1FA 4IU9A 4DKFA 4IKXA 4ZWBA 2JA6D 2INTA 5L6YC 4NI7A 1Y1VD 3HOYD 3BPOA 3HOXD 1CD9A 2XQBA 4A3LD 4A3MD 1KF9A 1INRA 3UF2A 2VUMD 1WU3I 1IL6A 2OQPA 3Q1SI 1M4AA 1CNT1 1BBNA 1Y1WD 1Z92A 1AXIA 4NEMA 2O27A 1Y6KL 2LMSA 4IU8A 4BBSD 3OG6A 3BPNA 1ITMA 2CFPA 5LQBA 3NCBA 4ZYRA 4LRLA 1IARA 4NN6A 4WRLB 4GS7A 4QIQA 1PW6A 1D9CA 1Y6NL 3SE3B 2O6IA 3D85C 3QAZA 2R93D 4EXPA 5D6KA 4JR9A 3H3VE 4YPGC 4NI9A 1HWHA 2O26A 2B91A 2B8XA 5C3ED 1Z7CA 3DUHC 2CFQA 2B63D 2XUTA 5EQGA 1FG9A 4PYPA 2L3OA 3I4ND 1EKUA 1EMRA 1RW5A 5TS9A 3D87A 4NEJA 5E4EA 2E9WC 3B5KA 1M4BA 2V8NA 4BBRD 4D2DA 4A93D 1M4RA 1AX8A 1NBPA 4YBQA 4D2CA 4I77Z 3INKC 5D22A 4Z5RD 1GNCA 4ZS7A 1VLKA 2ERJD 4IKVA 1I1RB 3I4MD 1CYLA 3HMXB 2B8YA 4GBZA 2H24A 4A3DD 5C7XA 3LB6A 2KZ1A 1M48A 3UEZE 4DKCA 4A3KD 3BPLA 4FA8E 3EJJA 4Q65A 5A2OA 4A3FD 1V7NV 1RHGA 5D71A 4LDSA 2R7ZD 4D2BA 4BY7D 4DKEA 4ZWCA 1BGCA 5A2NA 4IKWA 1EVSA 5FHXA 5C4XD 5D59A 4IKYA 2Z3QA 1A7MA 1J7VL 2D9QA 3VA2A 4OAAA 1F6FA 1EXZA 4O6KA 3H0GD 1SCFA 4YB9D 1V7MV 4EXNA 3O7QA 4DOHA 5FUCA 3QB1A 4BY1D 2LAGA 4BXXD 3IRHA 2Q7NB 1LQSL 4J4LC 2JA8D 4APSA 1BUYA 3WCYI 3HHCA 1HIKA 3NCCA 4A3ED 4IKZA 1LKIA 3WDOA 3QWRB 1HIJA 4A3BD 4X51A 2PSMA 3LB6B 3HOVD 1PY2A 1JLIA 4U4VA 1CSGA 1HWGA 1D9GA 1IJZA 4A3GD 3SE4B 2Q98A 4GC0A 5IYDD 1PW4A 4DKDA 2L3YA 3BESL 1IK0A 3PO3D 3HOUD 1Y6ML 1LK3A 1PVHB 4A3CD 4OH3A 2ILKA 3NCEA 3DI2A 1P9MB 5IYBD 1PGRA 2Q14A 4O9HA 4GRWA 1BGDA 1Y14A 4PS4A 1WCMD 1RFBA 1QVNA 1CN4C 2B90A 1F45B 4MHLA 2HYMB 1PV7A 2Y5YA 4J05A 1BCNA 4JREA 5IYCD 4NN7A 1HGUA 2IL6A 4ZF7A 3N0PA 4TPGA 1PV6A 2B5IA 5C65A 4A3JD 2JA7D 3N06A 4U4WA 4YUEC 1M4CA 5D58A 2Z3RA 5C44D 3PIWA 1M47A 1HULA 5D72A 3UF5A 4A3ID 1GA3A 3UX9A 3HHRA 5IP7D 5EQHA 1ETEA 1HZIA 3NPZA 4W6VA 1AU1A 1YKBA 3PO2D 3MZGA 3O7PA 3AYHA 3L5XA 4XNIA 1ITFA 3HOWD 1A22A 3PIVA 3TGXB 1B5LA 4XNJA 5EQIA 3OG4A 2D48A 3QT2C 1RCBA 1ALUA 3DLQI 4JA3A 4CNIC 1EERA 1BP3A 1FYHA 1ILKA 5D28B 2C35A 5KNHI 2B8ZA 1BGEA 4NN5A 5D70A 2B8UA 4TPHA 3QB7A 3FKID 4NKQC 3D48P 4GBYA 5IP9D 4UVMA
chains in the Genus database with same CATH topology
1BGCA 3SE3B 2O6IA 3D85C 3QAZA 3L5WI 4YQXA 1EVSA 2JA5D 2R93D 1BCNA 1ITIA 2CYKA 5FHXA 4EXPA 3S9DA 5C4XD 1A7MA 2Z3QA 1J7VL 2D9QA 3VA2A 5IYCD 2GMFA 3NCFA 5FLMD 3H3VE 1F6FA 4NN7A 1HGUA 2IL6A 1EXZA 1M49A 3DGCL 4YPGC 4ZF7A 4O6KA 1HWHA 2O26A 3G6DA 3H0GD 4NI9A 1SCFA 3N0PA 1V7MV 2B91A 4EXNA 3G9VB 2B8XA 5C3ED 3EW3A 3HOZD 1Z7CA 4DOHA 3DUHC 2R92D 1IRLA 1HUWA 5FUCA 2B5IA 3QB1A 2B63D 4BY1D 4A3JD 2JA7D 1ITLA 2LAGA 1FG9A 4RS1A 3OQ3A 4BXXD 3IRHA 2L3OA 1LQSL 3N06A 2Q7NB 4YDYI 4J4LC 3I4ND 4YUEC 2JA8D 1M4CA 1EKUA 2Z3RA 1BUYA 1EMRA 1M47A 3PIWA 5C44D 3DI3A 1HULA 3WCYI 1RW5A 1N1FA 3HHCA 5D72A 3UF5A 5TS9A 4DKFA 1HIKA 3D87A 4A3ID 3NCCA 2JA6D 2INTA 4NEJA 4A3ED 1GA3A 1LKIA 3UX9A 5E4EA 5L6YC 3HHRA 2E9WC 3QWRB 1HIJA 5IP7D 4A3BD 1ETEA 3B5KA 1Y1VD 4X51A 4NI7A 3HOYD 2PSMA 3BPOA 1HZIA 3LB6B 1M4BA 3HOXD 1CD9A 3HOVD 2XQBA 3NPZA 4BBRD 1PY2A 4A93D 4A3LD 1M4RA 4A3MD 1AU1A 1JLIA 1AX8A 1NBPA 1KF9A 1INRA 1CSGA 1YKBA 3UF2A 1HWGA 2VUMD 1WU3I 1D9GA 1IJZA 4I77Z 4A3GD 3SE4B 3INKC 3MZGA 3PO2D 5D22A 4Z5RD 2Q98A 1GNCA 3AYHA 5IYDD 4ZS7A 1IL6A 1VLKA 2ERJD 1I1RB 2OQPA 3I4MD 3HMXB 2B8YA 3L5XA 3Q1SI 1CYLA 4DKDA 2L3YA 3BESL 1M4AA 1IK0A 1ITFA 3HOWD 1CNT1 1A22A 3PO3D 2H24A 3PIVA 3TGXB 1BBNA 1B5LA 5C7XA 4A3DD 1Y1WD 3HOUD 3LB6A 1Z92A 1AXIA 3OG4A 4NEMA 2D48A 1Y6ML 1LK3A 1PVHB 2KZ1A 1M48A 3QT2C 1RCBA 3UEZE 4A3CD 1ALUA 2O27A 2ILKA 3DLQI 1Y6KL 3NCEA 2LMSA 4CNIC 4DKCA 1EERA 2B90A 3BPLA 1BP3A 4A3KD 1FYHA 3OG6A 4FA8E 3DI2A 4BBSD 3BPNA 1ILKA 3EJJA 1P9MB 5IYBD 1PGRA 5D28B 1ITMA 2C35A 5KNHI 2B8ZA 3NCBA 1BGEA 4NN5A 5D70A 5LQBA 4A3FD 2Q14A 4O9HA 1V7NV 4GRWA 1RHGA 2B8UA 5D71A 3QB7A 1BGDA 3FKID 4LRLA 4NKQC 1IARA 1Y14A 3D48P 4NN6A 2R7ZD 4BY7D 4WRLB 5IP9D 4PS4A 4GS7A 1WCMD 1RFBA 1PW6A 1CN4C 1QVNA 1D9CA 1Y6NL 1F45B 4MHLA 2HYMB 4DKEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JA7 D;  4BXX D;  2R93 D;  4A3K D;  2VUM D;  2JA5 D;  4BBS D;  3I4N D;  2JA8 D;  4A3G D;  3PO2 D;  5C4X D;  5C44 D;  5IYB D;  3AYH A;  5IYD D;  5IYC D;  2C35 A;  3I4M D;  5FLM D;  3H3V E;  4A3I D;  4A3F D;  2JA6 D;  4A3E D;  3HOW D;  4BY1 D;  3H0G D;  4A3D D;  3PO3 D;  5IP7 D;  4A3B D;  1Y1V D;  3FKI D;  1Y1W D;  3HOY D;  3HOU D;  1Y14 A;  3HOZ D;  5C3E D;  2R7Z D;  4BY7 D;  5IP9 D;  2R92 D;  3HOX D;  3HOV D;  1WCM D;  4BBR D;  4A3C D;  2B63 D;  4A93 D;  4A3L D;  4A3M D;  4A3J D; 
#chains in the Genus database with same CATH topology
 4TPJ A;  4YQX A;  3L5W I;  1ITI A;  2JA5 D;  2CYK A;  3S9D A;  2GMF A;  3NCF A;  5FLM D;  1M49 A;  3DGC L;  5GXB A;  3G6D A;  4U4T A;  3G9V B;  3HOZ D;  3EW3 A;  4LEP A;  2R92 D;  1IRL A;  4ZW9 A;  1HUW A;  1ITL A;  4RS1 A;  3OQ3 A;  4YDY I;  3DI3 A;  1N1F A;  4IU9 A;  4DKF A;  4IKX A;  4ZWB A;  2JA6 D;  2INT A;  5L6Y C;  4NI7 A;  1Y1V D;  3HOY D;  3BPO A;  3HOX D;  1CD9 A;  2XQB A;  4A3L D;  4A3M D;  1KF9 A;  1INR A;  3UF2 A;  2VUM D;  1WU3 I;  1IL6 A;  2OQP A;  3Q1S I;  1M4A A;  1CNT 1;  1BBN A;  1Y1W D;  1Z92 A;  1AXI A;  4NEM A;  2O27 A;  1Y6K L;  2LMS A;  4IU8 A;  4BBS D;  3OG6 A;  3BPN A;  1ITM A;  2CFP A;  5LQB A;  3NCB A;  4ZYR A;  4LRL A;  1IAR A;  4NN6 A;  4WRL B;  4GS7 A;  4QIQ A;  1PW6 A;  1D9C A;  1Y6N L;  3SE3 B;  2O6I A;  3D85 C;  3QAZ A;  2R93 D;  4EXP A;  5D6K A;  4JR9 A;  3H3V E;  4YPG C;  4NI9 A;  1HWH A;  2O26 A;  2B91 A;  2B8X A;  5C3E D;  1Z7C A;  3DUH C;  2CFQ A;  2B63 D;  2XUT A;  5EQG A;  1FG9 A;  4PYP A;  2L3O A;  3I4N D;  1EKU A;  1EMR A;  1RW5 A;  5TS9 A;  3D87 A;  4NEJ A;  5E4E A;  2E9W C;  3B5K A;  1M4B A;  2V8N A;  4BBR D;  4D2D A;  4A93 D;  1M4R A;  1AX8 A;  1NBP A;  4YBQ A;  4D2C A;  4I77 Z;  3INK C;  5D22 A;  4Z5R D;  1GNC A;  4ZS7 A;  1VLK A;  2ERJ D;  4IKV A;  1I1R B;  3I4M D;  1CYL A;  3HMX B;  2B8Y A;  4GBZ A;  2H24 A;  4A3D D;  5C7X A;  3LB6 A;  2KZ1 A;  1M48 A;  3UEZ E;  4DKC A;  4A3K D;  3BPL A;  4FA8 E;  3EJJ A;  4Q65 A;  5A2O A;  4A3F D;  1V7N V;  1RHG A;  5D71 A;  4LDS A;  2R7Z D;  4D2B A;  4BY7 D;  4DKE A;  4ZWC A;  1BGC A;  5A2N A;  4IKW A;  1EVS A;  5FHX A;  5C4X D;  5D59 A;  4IKY A;  2Z3Q A;  1A7M A;  1J7V L;  2D9Q A;  3VA2 A;  4OAA A;  1F6F A;  1EXZ A;  4O6K A;  3H0G D;  1SCF A;  4YB9 D;  1V7M V;  4EXN A;  3O7Q A;  4DOH A;  5FUC A;  3QB1 A;  4BY1 D;  2LAG A;  4BXX D;  3IRH A;  2Q7N B;  1LQS L;  4J4L C;  2JA8 D;  4APS A;  1BUY A;  3WCY I;  3HHC A;  1HIK A;  3NCC A;  4A3E D;  4IKZ A;  1LKI A;  3WDO A;  3QWR B;  1HIJ A;  4A3B D;  4X51 A;  2PSM A;  3LB6 B;  3HOV D;  1PY2 A;  1JLI A;  4U4V A;  1CSG A;  1HWG A;  1D9G A;  1IJZ A;  4A3G D;  3SE4 B;  2Q98 A;  4GC0 A;  5IYD D;  1PW4 A;  4DKD A;  2L3Y A;  3BES L;  1IK0 A;  3PO3 D;  3HOU D;  1Y6M L;  1LK3 A;  1PVH B;  4A3C D;  4OH3 A;  2ILK A;  3NCE A;  3DI2 A;  1P9M B;  5IYB D;  1PGR A;  2Q14 A;  4O9H A;  4GRW A;  1BGD A;  1Y14 A;  4PS4 A;  1WCM D;  1RFB A;  1QVN A;  1CN4 C;  2B90 A;  1F45 B;  4MHL A;  2HYM B;  1PV7 A;  2Y5Y A;  4J05 A;  1BCN A;  4JRE A;  5IYC D;  4NN7 A;  1HGU A;  2IL6 A;  4ZF7 A;  3N0P A;  4TPG A;  1PV6 A;  2B5I A;  5C65 A;  4A3J D;  2JA7 D;  3N06 A;  4U4W A;  4YUE C;  1M4C A;  5D58 A;  2Z3R A;  5C44 D;  3PIW A;  1M47 A;  1HUL A;  5D72 A;  3UF5 A;  4A3I D;  1GA3 A;  3UX9 A;  3HHR A;  5IP7 D;  5EQH A;  1ETE A;  1HZI A;  3NPZ A;  4W6V A;  1AU1 A;  1YKB A;  3PO2 D;  3MZG A;  3O7P A;  3AYH A;  3L5X A;  4XNI A;  1ITF A;  3HOW D;  1A22 A;  3PIV A;  3TGX B;  1B5L A;  4XNJ A;  5EQI A;  3OG4 A;  2D48 A;  3QT2 C;  1RCB A;  1ALU A;  3DLQ I;  4JA3 A;  4CNI C;  1EER A;  1BP3 A;  1FYH A;  1ILK A;  5D28 B;  2C35 A;  5KNH I;  2B8Z A;  1BGE A;  4NN5 A;  5D70 A;  2B8U A;  4TPH A;  3QB7 A;  3FKI D;  4NKQ C;  3D48 P;  4GBY A;  5IP9 D;  4UVM A; 
#chains in the Genus database with same CATH homology
 1BGC A;  3SE3 B;  2O6I A;  3D85 C;  3QAZ A;  3L5W I;  4YQX A;  1EVS A;  2JA5 D;  2R93 D;  1BCN A;  1ITI A;  2CYK A;  5FHX A;  4EXP A;  3S9D A;  5C4X D;  1A7M A;  2Z3Q A;  1J7V L;  2D9Q A;  3VA2 A;  5IYC D;  2GMF A;  3NCF A;  5FLM D;  3H3V E;  1F6F A;  4NN7 A;  1HGU A;  2IL6 A;  1EXZ A;  1M49 A;  3DGC L;  4YPG C;  4ZF7 A;  4O6K A;  1HWH A;  2O26 A;  3G6D A;  3H0G D;  4NI9 A;  1SCF A;  3N0P A;  1V7M V;  2B91 A;  4EXN A;  3G9V B;  2B8X A;  5C3E D;  3EW3 A;  3HOZ D;  1Z7C A;  4DOH A;  3DUH C;  2R92 D;  1IRL A;  1HUW A;  5FUC A;  2B5I A;  3QB1 A;  2B63 D;  4BY1 D;  4A3J D;  2JA7 D;  1ITL A;  2LAG A;  1FG9 A;  4RS1 A;  3OQ3 A;  4BXX D;  3IRH A;  2L3O A;  1LQS L;  3N06 A;  2Q7N B;  4YDY I;  4J4L C;  3I4N D;  4YUE C;  2JA8 D;  1M4C A;  1EKU A;  2Z3R A;  1BUY A;  1EMR A;  1M47 A;  3PIW A;  5C44 D;  3DI3 A;  1HUL A;  3WCY I;  1RW5 A;  1N1F A;  3HHC A;  5D72 A;  3UF5 A;  5TS9 A;  4DKF A;  1HIK A;  3D87 A;  4A3I D;  3NCC A;  2JA6 D;  2INT A;  4NEJ A;  4A3E D;  1GA3 A;  1LKI A;  3UX9 A;  5E4E A;  5L6Y C;  3HHR A;  2E9W C;  3QWR B;  1HIJ A;  5IP7 D;  4A3B D;  1ETE A;  3B5K A;  1Y1V D;  4X51 A;  4NI7 A;  3HOY D;  2PSM A;  3BPO A;  1HZI A;  3LB6 B;  1M4B A;  3HOX D;  1CD9 A;  3HOV D;  2XQB A;  3NPZ A;  4BBR D;  1PY2 A;  4A93 D;  4A3L D;  1M4R A;  4A3M D;  1AU1 A;  1JLI A;  1AX8 A;  1NBP A;  1KF9 A;  1INR A;  1CSG A;  1YKB A;  3UF2 A;  1HWG A;  2VUM D;  1WU3 I;  1D9G A;  1IJZ A;  4I77 Z;  4A3G D;  3SE4 B;  3INK C;  3MZG A;  3PO2 D;  5D22 A;  4Z5R D;  2Q98 A;  1GNC A;  3AYH A;  5IYD D;  4ZS7 A;  1IL6 A;  1VLK A;  2ERJ D;  1I1R B;  2OQP A;  3I4M D;  3HMX B;  2B8Y A;  3L5X A;  3Q1S I;  1CYL A;  4DKD A;  2L3Y A;  3BES L;  1M4A A;  1IK0 A;  1ITF A;  3HOW D;  1CNT 1;  1A22 A;  3PO3 D;  2H24 A;  3PIV A;  3TGX B;  1BBN A;  1B5L A;  5C7X A;  4A3D D;  1Y1W D;  3HOU D;  3LB6 A;  1Z92 A;  1AXI A;  3OG4 A;  4NEM A;  2D48 A;  1Y6M L;  1LK3 A;  1PVH B;  2KZ1 A;  1M48 A;  3QT2 C;  1RCB A;  3UEZ E;  4A3C D;  1ALU A;  2O27 A;  2ILK A;  3DLQ I;  1Y6K L;  3NCE A;  2LMS A;  4CNI C;  4DKC A;  1EER A;  2B90 A;  3BPL A;  1BP3 A;  4A3K D;  1FYH A;  3OG6 A;  4FA8 E;  3DI2 A;  4BBS D;  3BPN A;  1ILK A;  3EJJ A;  1P9M B;  5IYB D;  1PGR A;  5D28 B;  1ITM A;  2C35 A;  5KNH I;  2B8Z A;  3NCB A;  1BGE A;  4NN5 A;  5D70 A;  5LQB A;  4A3F D;  2Q14 A;  4O9H A;  1V7N V;  4GRW A;  1RHG A;  2B8U A;  5D71 A;  3QB7 A;  1BGD A;  3FKI D;  4LRL A;  4NKQ C;  1IAR A;  1Y14 A;  3D48 P;  4NN6 A;  2R7Z D;  4BY7 D;  4WRL B;  5IP9 D;  4PS4 A;  4GS7 A;  1WCM D;  1RFB A;  1PW6 A;  1CN4 C;  1QVN A;  1D9C A;  1Y6N L;  1F45 B;  4MHL A;  2HYM B;  4DKE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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