5IP9D

Structure of rna polymerase ii-tfiif complex
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
221
structure length
180
Chain Sequence
MNVSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Transcription initiation complex structures elucidate DNA opening.
pubmed doi rcsb
molecule tags Transcription
source organism Saccharomyces cerevisiae
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 49
structure length 180
sequence length 221
ec nomenclature
pdb deposition date 2016-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 5ip9D02
4A3ID 5IYBD 5C3ED 2JA5D 4BBSD 2VUMD 3HOXD 4A3GD 4BY7D 5IP9D 5IP7D 2JA6D 3FKID 2R7ZD 3PO3D 2R93D 3HOUD 3AYHA 4A3FD 2JA8D 4BBRD 3HOVD 3HOYD 2B63D 3PO2D 5C4XD 2JA7D 4A3LD 5IYDD 3I4MD 1Y1WD 1WCMD 5FLMD 4A3DD 5IYCD 4A3MD 3H0GD 4A3KD 4A3JD 3H3VE 4A3BD 2C35A 2R92D 4A93D 1Y1VD 4A3ED 4A3CD 1Y14A 3HOZD 4BXXD 3I4ND 4BY1D 3HOWD 5C44D
chains in the Genus database with same CATH superfamily
4A3GD 2Y5YA 4WRLB 4ZW9A 4IU9A 3O7PA 4D2CA 2JA6D 4LEPA 1BCNA 5D22A 4IKVA 3BPLA 1WU3I 2O27A 1ETEA 1GA3A 3INKC 3OQ3A 4EXNA 4GC0A 4TPHA 4BY1D 1HWGA 2JA5D 3D85C 1EKUA 4YPGC 1KF9A 3DI2A 2LAGA 1ITFA 1LK3A 4LRLA 1EERA 1IRLA 1HWHA 5C65A 3HOYD 1PW4A 2PSMA 3N0PA 4ZYRA 1Y1WD 3G9VB 2Q98A 4O9HA 1EXZA 4A3KD 4YBQA 4W6VA 1HUWA 4YDYI 1Y6KL 2CYKA 5C3ED 1RW5A 4ZF7A 4NEMA 3S9DA 2CFPA 4O6KA 1BUYA 3QB7A 1IJZA 3HOUD 5C7XA 4TPGA 1BGEA 2LMSA 1Y6ML 1ALUA 4IKZA 4YB9D 4NN5A 1IL6A 2OQPA 3L5XA 4OH3A 1Y1VD 1FG9A 3BPOA 1A7MA 3VA2A 3HOVD 2O6IA 3DGCL 1ILKA 1PV6A 1CN4C 1GNCA 2L3OA 4U4TA 4QIQA 4MHLA 4TPJA 5D6KA 3L5WI 2XUTA 1HIJA 1Y6NL 3HHCA 1VLKA 3FKID 3D48P 4J4LC 1M4RA 2Z3QA 3DI3A 3WDOA 3NPZA 4YUEC 4IU8A 3QB1A 5LQBA 3HHRA 3H0GD 4PS4A 3QAZA 1RFBA 1INRA 3BPNA 2VUMD 2CFQA 5IP9D 4J05A 2V8NA 1M4CA 3LB6A 1BBNA 2E9WC 1IK0A 1N1FA 3UF2A 1LQSL 5TS9A 3O7QA 3PO3D 1BGDA 3PO2D 4NEJA 2ILKA 2HYMB 3SE3B 3OG4A 5EQHA 5FLMD 1CYLA 1D9CA 1PVHB 3BESL 1HZIA 1JLIA 3OG6A 5A2OA 4BY7D 3UX9A 1HULA 3B5KA 3PIVA 4RS1A 4X51A 3AYHA 2INTA 1RCBA 3NCEA 4ZWBA 4NI9A 4A3LD 3G6DA 4ZS7A 3IRHA 2O26A 3I4MD 4NKQC 4DKFA 4Q65A 2XQBA 3QWRB 1HIKA 4A3BD 4APSA 1Y14A 2GMFA 4IKYA 4PYPA 5IP7D 2R7ZD 2D48A 1M4AA 1ITLA 5D70A 1M48A 1FYHA 3NCCA 4JA3A 3I4ND 3UF5A 1IARA 4DKCA 1M47A 4NI7A 2B8UA 4IKWA 4JREA 4CNIC 4YQXA 4EXPA 4NN7A 1A22A 3N06A 4BXXD 1AXIA 4I77Z 5FUCA 4GRWA 4XNJA 1EMRA 1EVSA 5L6YC 2B91A 1M49A 1QVNA 2D9QA 1F6FA 4FA8E 1YKBA 1B5LA 1V7NV 4GS7A 1PY2A 4BBSD 4IKXA 3HOXD 3SE4B 5EQIA 5D59A 1Z7CA 3D87A 3NCBA 2Q14A 2B8XA 1V7MV 1NBPA 3H3VE 2R92D 3MZGA 4U4WA 5D28B 4XNIA 2B90A 4A3ID 4OAAA 4UVMA 3EJJA 3DUHC 2H24A 4DKDA 3UEZE 4DOHA 3TGXB 1PGRA 1I1RB 5C4XD 1ITMA 1F45B 4DKEA 1J7VL 3DLQI 2Z3RA 5KNHI 4A3JD 4A93D 4LDSA 4U4VA 2Q7NB 1P9MB 4NN6A 3HOWD 5C44D 5IYBD 1HGUA 5E4EA 1D9GA 1ITIA 4GBZA 5A2NA 1CD9A 2JA8D 2JA7D 5IYDD 1BGCA 1Z92A 4A3MD 5D72A 4D2DA 2C35A 2ERJD 4GBYA 4A3CD 3HOZD 3HMXB 2KZ1A 2B5IA 2IL6A 5FHXA 2L3YA 4BBRD 1LKIA 4JR9A 2B63D 5D58A 1PV7A 1SCFA 1AU1A 1M4BA 3QT2C 4A3DD 5IYCD 3NCFA 3EW3A 3PIWA 4D2BA 1AX8A 5D71A 2B8YA 2R93D 4A3FD 2B8ZA 3LB6B 4ZWCA 5GXBA 1RHGA 1WCMD 5EQGA 1CNT1 3Q1SI 4Z5RD 1CSGA 4A3ED 1PW6A 1BP3A 3WCYI
chains in the Genus database with same CATH topology
4A3ID 3EJJA 3DUHC 4WRLB 1HIJA 1Y6NL 3HHCA 4A3GD 5IP7D 2JA6D 1VLKA 3FKID 2H24A 3D48P 2R7ZD 4J4LC 1M4RA 4DKDA 3UEZE 4DOHA 1BCNA 2Z3QA 5D22A 3DI3A 2D48A 3TGXB 1PGRA 1I1RB 3BPLA 5C4XD 3NPZA 1M4AA 1ITMA 4YUEC 1ITLA 1WU3I 2O27A 1F45B 4DKEA 1ETEA 3QB1A 1J7VL 3DLQI 3INKC 3HHRA 5D70A 5LQBA 2Z3RA 1GA3A 1M48A 5KNHI 3H0GD 1FYHA 4PS4A 4A3JD 3QAZA 1RFBA 4A93D 3NCCA 3OQ3A 4EXNA 1INRA 2Q7NB 3I4ND 3UF5A 1P9MB 4NN6A 4BY1D 5C44D 3BPNA 3HOWD 1HWGA 5IYBD 3D85C 1HGUA 1EKUA 2JA5D 4YPGC 2VUMD 5E4EA 1D9GA 5IP9D 1IARA 1KF9A 4DKCA 1M47A 3DI2A 1ITIA 2LAGA 4NI7A 1ITFA 1LK3A 2B8UA 4LRLA 1EERA 1M4CA 1CD9A 1IRLA 1HWHA 2JA8D 3HOYD 2PSMA 3N0PA 3LB6A 4CNIC 4YQXA 2JA7D 4EXPA 5IYDD 1BGCA 1Z92A 1BBNA 3G9VB 1Y1WD 2Q98A 2E9WC 4O9HA 4NN7A 1EXZA 1A22A 4A3KD 4A3MD 5D72A 1IK0A 1N1FA 2C35A 2ERJD 3N06A 1HUWA 4YDYI 1Y6KL 4A3CD 3HOZD 4BXXD 1AXIA 2CYKA 3HMXB 3UF2A 1LQSL 4I77Z 5C3ED 1RW5A 5TS9A 5FUCA 4ZF7A 4GRWA 4NEMA 2KZ1A 3S9DA 2B5IA 2IL6A 4O6KA 1BUYA 1EMRA 1BGDA 3QB7A 5FHXA 1IJZA 3HOUD 3PO3D 1EVSA 2L3YA 5C7XA 4BBRD 1LKIA 1BGEA 2LMSA 3PO2D 2B63D 1Y6ML 4NEJA 1ALUA 5L6YC 2B91A 1SCFA 2ILKA 1M49A 1AU1A 1M4BA 1QVNA 2HYMB 3SE3B 3QT2C 2D9QA 3OG4A 4NN5A 1IL6A 2OQPA 1F6FA 4FA8E 5FLMD 4A3DD 5IYCD 3L5XA 3NCFA 1CYLA 1YKBA 1D9CA 1PVHB 1Y1VD 1B5LA 1V7NV 1HZIA 1JLIA 3BESL 3EW3A 3OG6A 1FG9A 3PIWA 3BPOA 4GS7A 1PY2A 4BBSD 3HOXD 1AX8A 4BY7D 5D71A 3UX9A 2B8YA 1HULA 3B5KA 3PIVA 3SE4B 1A7MA 4RS1A 4X51A 2R93D 3AYHA 1Z7CA 3D87A 3VA2A 4A3FD 3NCBA 3HOVD 2INTA 2B8ZA 2O6IA 3DGCL 3LB6B 1RCBA 1ILKA 3NCEA 1CN4C 2Q14A 4NI9A 4A3LD 3G6DA 1GNCA 4ZS7A 3IRHA 2O26A 2L3OA 4NKQC 3I4MD 1RHGA 1WCMD 2GMFA 2B8XA 4DKFA 2XQBA 3QWRB 1V7MV 1CNT1 4MHLA 1NBPA 1HIKA 3Q1SI 3H3VE 4A3BD 4Z5RD 2R92D 3MZGA 1CSGA 4A3ED 1Y14A 1PW6A 3L5WI 5D28B 1BP3A 3WCYI 2B90A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3I D;  5IYB D;  5C3E D;  2JA5 D;  4BBS D;  2VUM D;  3HOX D;  4A3G D;  4BY7 D;  5IP9 D;  5IP7 D;  2JA6 D;  3FKI D;  2R7Z D;  3PO3 D;  2R93 D;  3HOU D;  3AYH A;  4A3F D;  2JA8 D;  4BBR D;  3HOV D;  3HOY D;  2B63 D;  3PO2 D;  5C4X D;  2JA7 D;  4A3L D;  5IYD D;  3I4M D;  1Y1W D;  1WCM D;  5FLM D;  4A3D D;  5IYC D;  4A3M D;  3H0G D;  4A3K D;  4A3J D;  3H3V E;  4A3B D;  2C35 A;  2R92 D;  4A93 D;  1Y1V D;  4A3E D;  4A3C D;  1Y14 A;  3HOZ D;  4BXX D;  3I4N D;  4BY1 D;  3HOW D;  5C44 D; 
#chains in the Genus database with same CATH topology
 4A3G D;  2Y5Y A;  4WRL B;  4ZW9 A;  4IU9 A;  3O7P A;  4D2C A;  2JA6 D;  4LEP A;  1BCN A;  5D22 A;  4IKV A;  3BPL A;  1WU3 I;  2O27 A;  1ETE A;  1GA3 A;  3INK C;  3OQ3 A;  4EXN A;  4GC0 A;  4TPH A;  4BY1 D;  1HWG A;  2JA5 D;  3D85 C;  1EKU A;  4YPG C;  1KF9 A;  3DI2 A;  2LAG A;  1ITF A;  1LK3 A;  4LRL A;  1EER A;  1IRL A;  1HWH A;  5C65 A;  3HOY D;  1PW4 A;  2PSM A;  3N0P A;  4ZYR A;  1Y1W D;  3G9V B;  2Q98 A;  4O9H A;  1EXZ A;  4A3K D;  4YBQ A;  4W6V A;  1HUW A;  4YDY I;  1Y6K L;  2CYK A;  5C3E D;  1RW5 A;  4ZF7 A;  4NEM A;  3S9D A;  2CFP A;  4O6K A;  1BUY A;  3QB7 A;  1IJZ A;  3HOU D;  5C7X A;  4TPG A;  1BGE A;  2LMS A;  1Y6M L;  1ALU A;  4IKZ A;  4YB9 D;  4NN5 A;  1IL6 A;  2OQP A;  3L5X A;  4OH3 A;  1Y1V D;  1FG9 A;  3BPO A;  1A7M A;  3VA2 A;  3HOV D;  2O6I A;  3DGC L;  1ILK A;  1PV6 A;  1CN4 C;  1GNC A;  2L3O A;  4U4T A;  4QIQ A;  4MHL A;  4TPJ A;  5D6K A;  3L5W I;  2XUT A;  1HIJ A;  1Y6N L;  3HHC A;  1VLK A;  3FKI D;  3D48 P;  4J4L C;  1M4R A;  2Z3Q A;  3DI3 A;  3WDO A;  3NPZ A;  4YUE C;  4IU8 A;  3QB1 A;  5LQB A;  3HHR A;  3H0G D;  4PS4 A;  3QAZ A;  1RFB A;  1INR A;  3BPN A;  2VUM D;  2CFQ A;  5IP9 D;  4J05 A;  2V8N A;  1M4C A;  3LB6 A;  1BBN A;  2E9W C;  1IK0 A;  1N1F A;  3UF2 A;  1LQS L;  5TS9 A;  3O7Q A;  3PO3 D;  1BGD A;  3PO2 D;  4NEJ A;  2ILK A;  2HYM B;  3SE3 B;  3OG4 A;  5EQH A;  5FLM D;  1CYL A;  1D9C A;  1PVH B;  3BES L;  1HZI A;  1JLI A;  3OG6 A;  5A2O A;  4BY7 D;  3UX9 A;  1HUL A;  3B5K A;  3PIV A;  4RS1 A;  4X51 A;  3AYH A;  2INT A;  1RCB A;  3NCE A;  4ZWB A;  4NI9 A;  4A3L D;  3G6D A;  4ZS7 A;  3IRH A;  2O26 A;  3I4M D;  4NKQ C;  4DKF A;  4Q65 A;  2XQB A;  3QWR B;  1HIK A;  4A3B D;  4APS A;  1Y14 A;  2GMF A;  4IKY A;  4PYP A;  5IP7 D;  2R7Z D;  2D48 A;  1M4A A;  1ITL A;  5D70 A;  1M48 A;  1FYH A;  3NCC A;  4JA3 A;  3I4N D;  3UF5 A;  1IAR A;  4DKC A;  1M47 A;  4NI7 A;  2B8U A;  4IKW A;  4JRE A;  4CNI C;  4YQX A;  4EXP A;  4NN7 A;  1A22 A;  3N06 A;  4BXX D;  1AXI A;  4I77 Z;  5FUC A;  4GRW A;  4XNJ A;  1EMR A;  1EVS A;  5L6Y C;  2B91 A;  1M49 A;  1QVN A;  2D9Q A;  1F6F A;  4FA8 E;  1YKB A;  1B5L A;  1V7N V;  4GS7 A;  1PY2 A;  4BBS D;  4IKX A;  3HOX D;  3SE4 B;  5EQI A;  5D59 A;  1Z7C A;  3D87 A;  3NCB A;  2Q14 A;  2B8X A;  1V7M V;  1NBP A;  3H3V E;  2R92 D;  3MZG A;  4U4W A;  5D28 B;  4XNI A;  2B90 A;  4A3I D;  4OAA A;  4UVM A;  3EJJ A;  3DUH C;  2H24 A;  4DKD A;  3UEZ E;  4DOH A;  3TGX B;  1PGR A;  1I1R B;  5C4X D;  1ITM A;  1F45 B;  4DKE A;  1J7V L;  3DLQ I;  2Z3R A;  5KNH I;  4A3J D;  4A93 D;  4LDS A;  4U4V A;  2Q7N B;  1P9M B;  4NN6 A;  3HOW D;  5C44 D;  5IYB D;  1HGU A;  5E4E A;  1D9G A;  1ITI A;  4GBZ A;  5A2N A;  1CD9 A;  2JA8 D;  2JA7 D;  5IYD D;  1BGC A;  1Z92 A;  4A3M D;  5D72 A;  4D2D A;  2C35 A;  2ERJ D;  4GBY A;  4A3C D;  3HOZ D;  3HMX B;  2KZ1 A;  2B5I A;  2IL6 A;  5FHX A;  2L3Y A;  4BBR D;  1LKI A;  4JR9 A;  2B63 D;  5D58 A;  1PV7 A;  1SCF A;  1AU1 A;  1M4B A;  3QT2 C;  4A3D D;  5IYC D;  3NCF A;  3EW3 A;  3PIW A;  4D2B A;  1AX8 A;  5D71 A;  2B8Y A;  2R93 D;  4A3F D;  2B8Z A;  3LB6 B;  4ZWC A;  5GXB A;  1RHG A;  1WCM D;  5EQG A;  1CNT 1;  3Q1S I;  4Z5R D;  1CSG A;  4A3E D;  1PW6 A;  1BP3 A;  3WCY I; 
#chains in the Genus database with same CATH homology
 4A3I D;  3EJJ A;  3DUH C;  4WRL B;  1HIJ A;  1Y6N L;  3HHC A;  4A3G D;  5IP7 D;  2JA6 D;  1VLK A;  3FKI D;  2H24 A;  3D48 P;  2R7Z D;  4J4L C;  1M4R A;  4DKD A;  3UEZ E;  4DOH A;  1BCN A;  2Z3Q A;  5D22 A;  3DI3 A;  2D48 A;  3TGX B;  1PGR A;  1I1R B;  3BPL A;  5C4X D;  3NPZ A;  1M4A A;  1ITM A;  4YUE C;  1ITL A;  1WU3 I;  2O27 A;  1F45 B;  4DKE A;  1ETE A;  3QB1 A;  1J7V L;  3DLQ I;  3INK C;  3HHR A;  5D70 A;  5LQB A;  2Z3R A;  1GA3 A;  1M48 A;  5KNH I;  3H0G D;  1FYH A;  4PS4 A;  4A3J D;  3QAZ A;  1RFB A;  4A93 D;  3NCC A;  3OQ3 A;  4EXN A;  1INR A;  2Q7N B;  3I4N D;  3UF5 A;  1P9M B;  4NN6 A;  4BY1 D;  5C44 D;  3BPN A;  3HOW D;  1HWG A;  5IYB D;  3D85 C;  1HGU A;  1EKU A;  2JA5 D;  4YPG C;  2VUM D;  5E4E A;  1D9G A;  5IP9 D;  1IAR A;  1KF9 A;  4DKC A;  1M47 A;  3DI2 A;  1ITI A;  2LAG A;  4NI7 A;  1ITF A;  1LK3 A;  2B8U A;  4LRL A;  1EER A;  1M4C A;  1CD9 A;  1IRL A;  1HWH A;  2JA8 D;  3HOY D;  2PSM A;  3N0P A;  3LB6 A;  4CNI C;  4YQX A;  2JA7 D;  4EXP A;  5IYD D;  1BGC A;  1Z92 A;  1BBN A;  3G9V B;  1Y1W D;  2Q98 A;  2E9W C;  4O9H A;  4NN7 A;  1EXZ A;  1A22 A;  4A3K D;  4A3M D;  5D72 A;  1IK0 A;  1N1F A;  2C35 A;  2ERJ D;  3N06 A;  1HUW A;  4YDY I;  1Y6K L;  4A3C D;  3HOZ D;  4BXX D;  1AXI A;  2CYK A;  3HMX B;  3UF2 A;  1LQS L;  4I77 Z;  5C3E D;  1RW5 A;  5TS9 A;  5FUC A;  4ZF7 A;  4GRW A;  4NEM A;  2KZ1 A;  3S9D A;  2B5I A;  2IL6 A;  4O6K A;  1BUY A;  1EMR A;  1BGD A;  3QB7 A;  5FHX A;  1IJZ A;  3HOU D;  3PO3 D;  1EVS A;  2L3Y A;  5C7X A;  4BBR D;  1LKI A;  1BGE A;  2LMS A;  3PO2 D;  2B63 D;  1Y6M L;  4NEJ A;  1ALU A;  5L6Y C;  2B91 A;  1SCF A;  2ILK A;  1M49 A;  1AU1 A;  1M4B A;  1QVN A;  2HYM B;  3SE3 B;  3QT2 C;  2D9Q A;  3OG4 A;  4NN5 A;  1IL6 A;  2OQP A;  1F6F A;  4FA8 E;  5FLM D;  4A3D D;  5IYC D;  3L5X A;  3NCF A;  1CYL A;  1YKB A;  1D9C A;  1PVH B;  1Y1V D;  1B5L A;  1V7N V;  1HZI A;  1JLI A;  3BES L;  3EW3 A;  3OG6 A;  1FG9 A;  3PIW A;  3BPO A;  4GS7 A;  1PY2 A;  4BBS D;  3HOX D;  1AX8 A;  4BY7 D;  5D71 A;  3UX9 A;  2B8Y A;  1HUL A;  3B5K A;  3PIV A;  3SE4 B;  1A7M A;  4RS1 A;  4X51 A;  2R93 D;  3AYH A;  1Z7C A;  3D87 A;  3VA2 A;  4A3F D;  3NCB A;  3HOV D;  2INT A;  2B8Z A;  2O6I A;  3DGC L;  3LB6 B;  1RCB A;  1ILK A;  3NCE A;  1CN4 C;  2Q14 A;  4NI9 A;  4A3L D;  3G6D A;  1GNC A;  4ZS7 A;  3IRH A;  2O26 A;  2L3O A;  4NKQ C;  3I4M D;  1RHG A;  1WCM D;  2GMF A;  2B8X A;  4DKF A;  2XQB A;  3QWR B;  1V7M V;  1CNT 1;  4MHL A;  1NBP A;  1HIK A;  3Q1S I;  3H3V E;  4A3B D;  4Z5R D;  2R92 D;  3MZG A;  1CSG A;  4A3E D;  1Y14 A;  1PW6 A;  3L5W I;  5D28 B;  1BP3 A;  3WCY I;  2B90 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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