5FLMD

Structure of transcribing mammalian rna polymerase ii
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
128
structure length
128
Chain Sequence
EEDASQLIFPKEFETAETLLNSEVHMLLEHRKQQNESAEDEQELSEVFMKTLNYTARFSRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGRFEDEELQQILDDIQTKRSFQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Transcribing Mammalian RNA Polymerase II
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASE
total genus 43
structure length 128
sequence length 128
ec nomenclature
pdb deposition date 2015-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 5flmD00
1Y1VD 2B63D 5IP7D 1Y1WD 3HOUD 5C3ED 5FLMD 4A3JD 4A3KD 2VUMD 3HOVD 5IYCD 3I4ND 5IYDD 4A3LD 3AYHA 5C44D 3H3VE 3HOYD 4A3ID 4A3GD 4A3FD 3I4MD 2C35A 1Y14A 2R92D 4A3MD 4BXXD 2R93D 2JA6D 5IP9D 4A3DD 4A93D 2JA7D 3HOXD 5C4XD 2JA8D 4A3ED 3HOZD 3HOWD 4A3CD 4BY7D 4BY1D 3H0GD 3PO2D 4A3BD 4BBSD 3PO3D 3FKID 2JA5D 4BBRD 2R7ZD 1WCMD 5IYBD
chains in the Genus database with same CATH superfamily
1Y1WD 4PYPA 1EERA 4DKDA 5IYCD 4A3LD 1ITLA 2CFQA 4JA3A 1KF9A 4DKFA 2O26A 3HOXD 5C4XD 3HOZD 4JREA 1PY2A 1B5LA 3G9VB 1ITFA 2B5IA 4D2CA 1ITIA 1WU3I 1SCFA 5D59A 3WCYI 1BCNA 1Y14A 4BXXD 4D2DA 1A7MA 1BP3A 4BY1D 4D2BA 4BBSD 4U4WA 1QVNA 5D72A 2Q98A 1IRLA 2ILKA 3DI2A 4TPHA 5EQGA 3HOYD 4NEJA 1HIJA 5D70A 5EQIA 3QWRB 4IKZA 4A3FD 2KZ1A 1J7VL 4A3DD 2JA7D 1YKBA 2ERJD 1FG9A 3LB6B 5D71A 1M48A 1EVSA 3QB1A 5D6KA 3HMXB 1HULA 1D9CA 2CFPA 4IU9A 2XUTA 3NPZA 1ITMA 4ZWBA 1VLKA 3LB6A 5GXBA 4A3JD 1HWGA 4YDYI 1JLIA 4NKQC 4O9HA 1BGEA 3B5KA 4NI7A 3NCFA 2O6IA 4APSA 2Q14A 3OG6A 3D87A 2B8ZA 1D9GA 1RW5A 1RCBA 1BGCA 3UEZE 2D48A 4ZWCA 3BPLA 1AX8A 4YB9D 1AXIA 3O7QA 2INTA 3H3VE 3EJJA 3SE3B 1GNCA 4Z5RD 2V8NA 2HYMB 1BUYA 5IP9D 4A93D 4XNIA 1F6FA 1EKUA 1Y6KL 3DLQI 5C3ED 4A3KD 1CSGA 2GMFA 4TPJA 3NCEA 2Z3QA 4JR9A 1CNT1 2XQBA 3I4MD 3L5XA 4EXPA 3INKC 3N06A 4YBQA 3BESL 3HOWD 1PV6A 5FUCA 1PW4A 3G6DA 3PO3D 1M4BA 1PVHB 2B8UA 1FYHA 3HOUD 4WRLB 3QT2C 3DGCL 1I1RB 3TGXB 4YUEC 4GC0A 2C35A 1INRA 1BBNA 3SE4B 4ZYRA 4IKXA 1HIKA 4YQXA 1NBPA 4XNJA 3NCBA 4ZF7A 3Q1SI 3MZGA 2B91A 1Y6NL 3PIVA 4NN7A 4NN6A 4U4TA 1CD9A 3DI3A 3L5WI 3BPOA 5FHXA 5A2NA 4DKCA 1V7NV 1IK0A 5FLMD 5TS9A 4DKEA 4ZS7A 2OQPA 4W6VA 3HHRA 4YPGC 4GRWA 4A3ED 4A3BD 4DOHA 5L6YC 1WCMD 4QIQA 2B63D 3NCCA 5IP7D 1V7MV 4GBYA 3I4ND 3DUHC 3AYHA 3QB7A 4NEMA 3UX9A 5C44D 1RFBA 3WDOA 5E4EA 1ALUA 3D85C 2LMSA 2B90A 1Z92A 1ETEA 4BY7D 4TPGA 1Y6ML 1GA3A 4UVMA 1IARA 5IYBD 1N1FA 3EW3A 3OQ3A 2B8YA 3S9DA 4OAAA 1PGRA 4LDSA 1M4RA 4NI9A 3BPNA 4IU8A 4J4LC 1CYLA 4BBRD 1M4CA 1Z7CA 3N0PA 1BGDA 1PW6A 3HHCA 4LEPA 2H24A 4O6KA 2LAGA 3UF5A 1EMRA 4NN5A 2O27A 5EQHA 4I77Z 3UF2A 2R93D 1IJZA 2CYKA 2L3YA 3H0GD 1LK3A 1P9MB 1M47A 2IL6A 5LQBA 3VA2A 1LQSL 3QAZA 2E9WC 1ILKA 1M4AA 2VUMD 1HGUA 3HOVD 3OG4A 4IKWA 2Y5YA 4IKYA 1HWHA 1F45B 4X51A 2B8XA 3PIWA 1AU1A 4MHLA 3O7PA 4A3CD 3IRHA 4LRLA 5KNHI 1PV7A 4RS1A 4FA8E 2JA5D 1M49A 1Y1VD 5D28B 5IYDD 4A3ID 4A3GD 3D48P 1EXZA 2Z3RA 4A3MD 2JA6D 4IKVA 2JA8D 4PS4A 1HUWA 5D22A 4ZW9A 3PO2D 1A22A 5A2OA 1RHGA 2D9QA 2R7ZD 4GBZA 2L3OA 4CNIC 4EXNA 5D58A 1IL6A 5C65A 1CN4C 4U4VA 4GS7A 4J05A 2R92D 1HZIA 5C7XA 4OH3A 1LKIA 2Q7NB 3FKID 2PSMA 4Q65A
chains in the Genus database with same CATH topology
1ITMA 1Z7CA 3N0PA 1BGDA 1PW6A 3NCBA 1VLKA 3LB6A 4ZF7A 3HHCA 1Y1WD 2H24A 4O6KA 4A3JD 2LAGA 1EERA 1HWGA 3UF5A 4YDYI 4DKDA 5IYCD 2PSMA 4A3LD 1EMRA 3Q1SI 4NN5A 3MZGA 2B91A 1JLIA 1Y6NL 2O27A 4NKQC 3PIVA 4NN7A 4O9HA 1ITLA 1BGEA 3B5KA 4NN6A 3NCFA 4NI7A 2O6IA 1CD9A 1KF9A 4I77Z 4DKFA 3DI3A 3UF2A 2O26A 3L5WI 2R93D 1IJZA 2CYKA 2Q14A 3BPOA 3OG6A 3HOXD 5C4XD 3HOZD 2L3YA 3D87A 5FHXA 3H0GD 2B8ZA 1D9GA 1LK3A 1P9MB 1PY2A 1RW5A 1M47A 2IL6A 1RCBA 1BGCA 3UEZE 3VA2A 4DKCA 1LQSL 1B5LA 3QAZA 5LQBA 2D48A 1V7NV 3BPLA 3G9VB 1ITFA 1AX8A 2E9WC 2B5IA 1ILKA 1IK0A 1M4AA 2VUMD 5FLMD 1ITIA 5TS9A 1HGUA 4DKEA 3HOVD 1AXIA 3OG4A 4ZS7A 2INTA 3H3VE 1WU3I 2OQPA 1SCFA 3EJJA 3HHRA 3SE3B 3WCYI 1HWHA 1F45B 1GNCA 4X51A 2B8XA 1BCNA 1Y14A 4Z5RD 3PIWA 4BXXD 1AU1A 2HYMB 4YPGC 1BUYA 5IP9D 4A93D 1A7MA 4MHLA 1BP3A 4GRWA 3IRHA 4A3ED 4A3CD 1F6FA 4BY1D 4A3BD 4LRLA 4BBSD 1EKUA 4DOHA 4RS1A 5KNHI 4FA8E 2JA5D 5L6YC 1WCMD 1M49A 1QVNA 5D72A 1Y1VD 2Q98A 2B63D 5D28B 1IRLA 1Y6KL 2ILKA 3NCCA 5IP7D 3DLQI 5C3ED 4A3KD 1CSGA 3DI2A 2GMFA 1V7MV 3NCEA 2Z3QA 3I4ND 3DUHC 5IYDD 3AYHA 3QB7A 4NEMA 3UX9A 5C44D 3HOYD 4NEJA 1RFBA 4A3ID 5E4EA 1HIJA 1ALUA 1CNT1 3D85C 5D70A 2XQBA 4A3GD 3D48P 1EXZA 3QWRB 2LMSA 2Z3RA 4A3FD 3I4MD 2KZ1A 3L5XA 4EXPA 3INKC 2B90A 4A3MD 1Z92A 2JA6D 1J7VL 4A3DD 2JA7D 1ETEA 3N06A 2JA8D 4PS4A 3BESL 3HOWD 4BY7D 1YKBA 1HUWA 5D22A 5FUCA 3PO2D 3G6DA 1Y6ML 1GA3A 3PO3D 1M4BA 1PVHB 2ERJD 1IARA 1A22A 1RHGA 2D9QA 2B8UA 5IYBD 2R7ZD 1N1FA 3EW3A 2L3OA 4CNIC 4EXNA 1FYHA 3OQ3A 1FG9A 3LB6B 3HOUD 1IL6A 5D71A 1M48A 1EVSA 2B8YA 1CN4C 3QT2C 4WRLB 3S9DA 3DGCL 3NPZA 1I1RB 3QB1A 3TGXB 4YUEC 1PGRA 2C35A 4GS7A 2R92D 3HMXB 1INRA 1BBNA 3SE4B 1HULA 1HZIA 5C7XA 1M4RA 4NI9A 3BPNA 1D9CA 1LKIA 2Q7NB 4J4LC 1CYLA 1HIKA 3FKID 1NBPA 4YQXA 4BBRD 1M4CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Y1V D;  2B63 D;  5IP7 D;  1Y1W D;  3HOU D;  5C3E D;  5FLM D;  4A3J D;  4A3K D;  2VUM D;  3HOV D;  5IYC D;  3I4N D;  5IYD D;  4A3L D;  3AYH A;  5C44 D;  3H3V E;  3HOY D;  4A3I D;  4A3G D;  4A3F D;  3I4M D;  2C35 A;  1Y14 A;  2R92 D;  4A3M D;  4BXX D;  2R93 D;  2JA6 D;  5IP9 D;  4A3D D;  4A93 D;  2JA7 D;  3HOX D;  5C4X D;  2JA8 D;  4A3E D;  3HOZ D;  3HOW D;  4A3C D;  4BY7 D;  4BY1 D;  3H0G D;  3PO2 D;  4A3B D;  4BBS D;  3PO3 D;  3FKI D;  2JA5 D;  4BBR D;  2R7Z D;  1WCM D;  5IYB D; 
#chains in the Genus database with same CATH topology
 1Y1W D;  4PYP A;  1EER A;  4DKD A;  5IYC D;  4A3L D;  1ITL A;  2CFQ A;  4JA3 A;  1KF9 A;  4DKF A;  2O26 A;  3HOX D;  5C4X D;  3HOZ D;  4JRE A;  1PY2 A;  1B5L A;  3G9V B;  1ITF A;  2B5I A;  4D2C A;  1ITI A;  1WU3 I;  1SCF A;  5D59 A;  3WCY I;  1BCN A;  1Y14 A;  4BXX D;  4D2D A;  1A7M A;  1BP3 A;  4BY1 D;  4D2B A;  4BBS D;  4U4W A;  1QVN A;  5D72 A;  2Q98 A;  1IRL A;  2ILK A;  3DI2 A;  4TPH A;  5EQG A;  3HOY D;  4NEJ A;  1HIJ A;  5D70 A;  5EQI A;  3QWR B;  4IKZ A;  4A3F D;  2KZ1 A;  1J7V L;  4A3D D;  2JA7 D;  1YKB A;  2ERJ D;  1FG9 A;  3LB6 B;  5D71 A;  1M48 A;  1EVS A;  3QB1 A;  5D6K A;  3HMX B;  1HUL A;  1D9C A;  2CFP A;  4IU9 A;  2XUT A;  3NPZ A;  1ITM A;  4ZWB A;  1VLK A;  3LB6 A;  5GXB A;  4A3J D;  1HWG A;  4YDY I;  1JLI A;  4NKQ C;  4O9H A;  1BGE A;  3B5K A;  4NI7 A;  3NCF A;  2O6I A;  4APS A;  2Q14 A;  3OG6 A;  3D87 A;  2B8Z A;  1D9G A;  1RW5 A;  1RCB A;  1BGC A;  3UEZ E;  2D48 A;  4ZWC A;  3BPL A;  1AX8 A;  4YB9 D;  1AXI A;  3O7Q A;  2INT A;  3H3V E;  3EJJ A;  3SE3 B;  1GNC A;  4Z5R D;  2V8N A;  2HYM B;  1BUY A;  5IP9 D;  4A93 D;  4XNI A;  1F6F A;  1EKU A;  1Y6K L;  3DLQ I;  5C3E D;  4A3K D;  1CSG A;  2GMF A;  4TPJ A;  3NCE A;  2Z3Q A;  4JR9 A;  1CNT 1;  2XQB A;  3I4M D;  3L5X A;  4EXP A;  3INK C;  3N06 A;  4YBQ A;  3BES L;  3HOW D;  1PV6 A;  5FUC A;  1PW4 A;  3G6D A;  3PO3 D;  1M4B A;  1PVH B;  2B8U A;  1FYH A;  3HOU D;  4WRL B;  3QT2 C;  3DGC L;  1I1R B;  3TGX B;  4YUE C;  4GC0 A;  2C35 A;  1INR A;  1BBN A;  3SE4 B;  4ZYR A;  4IKX A;  1HIK A;  4YQX A;  1NBP A;  4XNJ A;  3NCB A;  4ZF7 A;  3Q1S I;  3MZG A;  2B91 A;  1Y6N L;  3PIV A;  4NN7 A;  4NN6 A;  4U4T A;  1CD9 A;  3DI3 A;  3L5W I;  3BPO A;  5FHX A;  5A2N A;  4DKC A;  1V7N V;  1IK0 A;  5FLM D;  5TS9 A;  4DKE A;  4ZS7 A;  2OQP A;  4W6V A;  3HHR A;  4YPG C;  4GRW A;  4A3E D;  4A3B D;  4DOH A;  5L6Y C;  1WCM D;  4QIQ A;  2B63 D;  3NCC A;  5IP7 D;  1V7M V;  4GBY A;  3I4N D;  3DUH C;  3AYH A;  3QB7 A;  4NEM A;  3UX9 A;  5C44 D;  1RFB A;  3WDO A;  5E4E A;  1ALU A;  3D85 C;  2LMS A;  2B90 A;  1Z92 A;  1ETE A;  4BY7 D;  4TPG A;  1Y6M L;  1GA3 A;  4UVM A;  1IAR A;  5IYB D;  1N1F A;  3EW3 A;  3OQ3 A;  2B8Y A;  3S9D A;  4OAA A;  1PGR A;  4LDS A;  1M4R A;  4NI9 A;  3BPN A;  4IU8 A;  4J4L C;  1CYL A;  4BBR D;  1M4C A;  1Z7C A;  3N0P A;  1BGD A;  1PW6 A;  3HHC A;  4LEP A;  2H24 A;  4O6K A;  2LAG A;  3UF5 A;  1EMR A;  4NN5 A;  2O27 A;  5EQH A;  4I77 Z;  3UF2 A;  2R93 D;  1IJZ A;  2CYK A;  2L3Y A;  3H0G D;  1LK3 A;  1P9M B;  1M47 A;  2IL6 A;  5LQB A;  3VA2 A;  1LQS L;  3QAZ A;  2E9W C;  1ILK A;  1M4A A;  2VUM D;  1HGU A;  3HOV D;  3OG4 A;  4IKW A;  2Y5Y A;  4IKY A;  1HWH A;  1F45 B;  4X51 A;  2B8X A;  3PIW A;  1AU1 A;  4MHL A;  3O7P A;  4A3C D;  3IRH A;  4LRL A;  5KNH I;  1PV7 A;  4RS1 A;  4FA8 E;  2JA5 D;  1M49 A;  1Y1V D;  5D28 B;  5IYD D;  4A3I D;  4A3G D;  3D48 P;  1EXZ A;  2Z3R A;  4A3M D;  2JA6 D;  4IKV A;  2JA8 D;  4PS4 A;  1HUW A;  5D22 A;  4ZW9 A;  3PO2 D;  1A22 A;  5A2O A;  1RHG A;  2D9Q A;  2R7Z D;  4GBZ A;  2L3O A;  4CNI C;  4EXN A;  5D58 A;  1IL6 A;  5C65 A;  1CN4 C;  4U4V A;  4GS7 A;  4J05 A;  2R92 D;  1HZI A;  5C7X A;  4OH3 A;  1LKI A;  2Q7N B;  3FKI D;  2PSM A;  4Q65 A; 
#chains in the Genus database with same CATH homology
 1ITM A;  1Z7C A;  3N0P A;  1BGD A;  1PW6 A;  3NCB A;  1VLK A;  3LB6 A;  4ZF7 A;  3HHC A;  1Y1W D;  2H24 A;  4O6K A;  4A3J D;  2LAG A;  1EER A;  1HWG A;  3UF5 A;  4YDY I;  4DKD A;  5IYC D;  2PSM A;  4A3L D;  1EMR A;  3Q1S I;  4NN5 A;  3MZG A;  2B91 A;  1JLI A;  1Y6N L;  2O27 A;  4NKQ C;  3PIV A;  4NN7 A;  4O9H A;  1ITL A;  1BGE A;  3B5K A;  4NN6 A;  3NCF A;  4NI7 A;  2O6I A;  1CD9 A;  1KF9 A;  4I77 Z;  4DKF A;  3DI3 A;  3UF2 A;  2O26 A;  3L5W I;  2R93 D;  1IJZ A;  2CYK A;  2Q14 A;  3BPO A;  3OG6 A;  3HOX D;  5C4X D;  3HOZ D;  2L3Y A;  3D87 A;  5FHX A;  3H0G D;  2B8Z A;  1D9G A;  1LK3 A;  1P9M B;  1PY2 A;  1RW5 A;  1M47 A;  2IL6 A;  1RCB A;  1BGC A;  3UEZ E;  3VA2 A;  4DKC A;  1LQS L;  1B5L A;  3QAZ A;  5LQB A;  2D48 A;  1V7N V;  3BPL A;  3G9V B;  1ITF A;  1AX8 A;  2E9W C;  2B5I A;  1ILK A;  1IK0 A;  1M4A A;  2VUM D;  5FLM D;  1ITI A;  5TS9 A;  1HGU A;  4DKE A;  3HOV D;  1AXI A;  3OG4 A;  4ZS7 A;  2INT A;  3H3V E;  1WU3 I;  2OQP A;  1SCF A;  3EJJ A;  3HHR A;  3SE3 B;  3WCY I;  1HWH A;  1F45 B;  1GNC A;  4X51 A;  2B8X A;  1BCN A;  1Y14 A;  4Z5R D;  3PIW A;  4BXX D;  1AU1 A;  2HYM B;  4YPG C;  1BUY A;  5IP9 D;  4A93 D;  1A7M A;  4MHL A;  1BP3 A;  4GRW A;  3IRH A;  4A3E D;  4A3C D;  1F6F A;  4BY1 D;  4A3B D;  4LRL A;  4BBS D;  1EKU A;  4DOH A;  4RS1 A;  5KNH I;  4FA8 E;  2JA5 D;  5L6Y C;  1WCM D;  1M49 A;  1QVN A;  5D72 A;  1Y1V D;  2Q98 A;  2B63 D;  5D28 B;  1IRL A;  1Y6K L;  2ILK A;  3NCC A;  5IP7 D;  3DLQ I;  5C3E D;  4A3K D;  1CSG A;  3DI2 A;  2GMF A;  1V7M V;  3NCE A;  2Z3Q A;  3I4N D;  3DUH C;  5IYD D;  3AYH A;  3QB7 A;  4NEM A;  3UX9 A;  5C44 D;  3HOY D;  4NEJ A;  1RFB A;  4A3I D;  5E4E A;  1HIJ A;  1ALU A;  1CNT 1;  3D85 C;  5D70 A;  2XQB A;  4A3G D;  3D48 P;  1EXZ A;  3QWR B;  2LMS A;  2Z3R A;  4A3F D;  3I4M D;  2KZ1 A;  3L5X A;  4EXP A;  3INK C;  2B90 A;  4A3M D;  1Z92 A;  2JA6 D;  1J7V L;  4A3D D;  2JA7 D;  1ETE A;  3N06 A;  2JA8 D;  4PS4 A;  3BES L;  3HOW D;  4BY7 D;  1YKB A;  1HUW A;  5D22 A;  5FUC A;  3PO2 D;  3G6D A;  1Y6M L;  1GA3 A;  3PO3 D;  1M4B A;  1PVH B;  2ERJ D;  1IAR A;  1A22 A;  1RHG A;  2D9Q A;  2B8U A;  5IYB D;  2R7Z D;  1N1F A;  3EW3 A;  2L3O A;  4CNI C;  4EXN A;  1FYH A;  3OQ3 A;  1FG9 A;  3LB6 B;  3HOU D;  1IL6 A;  5D71 A;  1M48 A;  1EVS A;  2B8Y A;  1CN4 C;  3QT2 C;  4WRL B;  3S9D A;  3DGC L;  3NPZ A;  1I1R B;  3QB1 A;  3TGX B;  4YUE C;  1PGR A;  2C35 A;  4GS7 A;  2R92 D;  3HMX B;  1INR A;  1BBN A;  3SE4 B;  1HUL A;  1HZI A;  5C7X A;  1M4R A;  4NI9 A;  3BPN A;  1D9C A;  1LKI A;  2Q7N B;  4J4L C;  1CYL A;  1HIK A;  3FKI D;  1NBP A;  4YQX A;  4BBR D;  1M4C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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