5IYBD

Human core-pic in the open state
Total Genus 46
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
129
structure length
129
Chain Sequence
EEDASQLIFPKEFETAETLLNSEVHMLLEHRKQQNESAEDEQELSEVFMKTLNYTARFSRFKNRETIASVRSLLLQKKLHKFELACLANLCPETAEESKALIPSLEGRFEDEELQQILDDIQTKRSFQY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
molecule tags Transcription, transferase/dna
source organism Homo sapiens
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 46
structure length 129
sequence length 129
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF03874 RNA_pol_Rpb4 RNA polymerase Rpb4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.40 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; Growth Hormone; Chain: A; 5iybD00
4A3BD 2C35A 1Y1WD 4BXXD 3I4ND 4A3ID 4A3ED 5FLMD 2JA7D 2R92D 4A93D 5C3ED 4A3FD 3HOZD 5IP9D 4BBSD 5C44D 2R7ZD 5IYCD 3I4MD 3PO2D 5C4XD 3HOUD 3H3VE 2B63D 3HOXD 2JA6D 4A3DD 2JA5D 4A3KD 2JA8D 5IP7D 4BBRD 3HOYD 4A3CD 1WCMD 4BY1D 5IYBD 1Y1VD 2VUMD 3HOVD 3HOWD 5IYDD 4A3LD 2R93D 3FKID 3H0GD 4A3JD 4BY7D 3PO3D 3AYHA 4A3MD 4A3GD 1Y14A
chains in the Genus database with same CATH superfamily
3DLQI 1Z92A 2L3OA 1RCBA 1HIJA 1WU3I 3QB7A 4IKXA 1M47A 4PYPA 4MHLA 5D72A 1GA3A 1IRLA 1HIKA 3D48P 1ETEA 1BP3A 2GMFA 4NI9A 3G6DA 1EMRA 3IRHA 5D58A 1PW4A 3QAZA 5C7XA 4DKCA 4UVMA 1Y6NL 2V8NA 4A3KD 5GXBA 4TPJA 4A3LD 1AU1A 1M4CA 4A3BD 4YDYI 1CSGA 5C3ED 4LEPA 1IJZA 1V7NV 1FYHA 2O26A 1Z7CA 5EQIA 3D85C 4U4WA 4GRWA 1D9GA 2R93D 4A3JD 1M49A 3D87A 3HHRA 4OH3A 1M4RA 1HWHA 4CNIC 1P9MB 5TS9A 3LB6A 1EKUA 1HWGA 2E9WC 5IYCD 4JA3A 4YB9D 3QB1A 4A3DD 2JA8D 4BBRD 2VUMD 2Z3RA 1M4AA 4O6KA 1CN4C 1ITFA 1ILKA 4D2BA 1PGRA 5D6KA 4IKWA 1IK0A 4DKFA 1F6FA 1CD9A 2Q98A 1YKBA 2O6IA 1M48A 1CNT1 3DI3A 2JA5D 4DKEA 3I4ND 3S9DA 3BPLA 4A93D 1NBPA 5IP9D 3NCBA 3NCEA 3HOUD 1KF9A 3TGXB 2CYKA 1HGUA 2Y5YA 4BY7D 1Y6KL 1CYLA 2LMSA 4D2CA 1HULA 2B90A 1RFBA 4A3FD 2B8ZA 3H3VE 4IKZA 5D22A 4Q65A 3N0PA 5E4EA 3UEZE 1BCNA 3WDOA 4ZWCA 4EXPA 4BBSD 4TPGA 1B5LA 4PS4A 1ITMA 4O9HA 3VA2A 4J05A 5A2NA 4GBYA 2HYMB 5FUCA 3PO2D 1LQSL 5IP7D 2H24A 2B5IA 5LQBA 2B91A 3H0GD 3SE4B 3HOWD 1GNCA 5FLMD 5EQGA 3NCFA 3EJJA 4U4VA 4W6VA 3NPZA 1J7VL 3WCYI 5FHXA 4A3CD 4ZF7A 3QWRB 5KNHI 3LB6B 4APSA 3SE3B 3BESL 4NEJA 4U4TA 3L5WI 1PVHB 3INKC 3UF2A 4ZYRA 4FA8E 1RW5A 5D71A 5C4XD 2B63D 3NCCA 5IYBD 3OG6A 3N06A 1BGDA 1HZIA 1QVNA 4JREA 4A3MD 3HOYD 2INTA 4JR9A 1LKIA 4TPHA 4NI7A 3DUHC 1FG9A 5EQHA 2R7ZD 5L6YC 4WRLB 3OG4A 3QT2C 4ZW9A 4NN7A 1Y14A 1PW6A 4J4LC 3BPNA 4YPGC 3HHCA 2JA7D 3HOZD 2KZ1A 3OQ3A 1BUYA 2JA6D 4ZWBA 1M4BA 2L3YA 4GBZA 3HMXB 1RHGA 1A7MA 4IKVA 4BXXD 1N1FA 4LDSA 4LRLA 4XNIA 5D28B 2Q7NB 4A3ED 2R92D 4NN5A 2IL6A 3UF5A 4QIQA 4ZS7A 3PIVA 5D70A 2B8UA 1AXIA 3B5KA 4IKYA 4EXNA 2D9QA 3BPOA 4OAAA 4Z5RD 1SCFA 4DOHA 2ERJD 2B8XA 3FKID 4YUEC 1LK3A 1ITIA 4A3GD 1EXZA 2CFPA 2Z3QA 3UX9A 2CFQA 4RS1A 3EW3A 3O7QA 4DKDA 2PSMA 1EERA 3O7PA 1IL6A 2XQBA 1PV7A 3I4MD 1A22A 1BBNA 4YBQA 4I77Z 1V7MV 4NKQC 4NN6A 3PIWA 1I1RB 1AX8A 5C65A 2XUTA 4D2DA 2C35A 2D48A 3DI2A 1IARA 5C44D 1Y6ML 2Q14A 1BGEA 4IU8A 1D9CA 2ILKA 3Q1SI 4IU9A 5IYDD 1JLIA 1PY2A 4X51A 3DGCL 4NEMA 2OQPA 5A2OA 3G9VB 1INRA 4GS7A 1BGCA 2LAGA 1Y1WD 4A3ID 2B8YA 1PV6A 1VLKA 4XNJA 1ITLA 1EVSA 3L5XA 3HOXD 2O27A 5D59A 4YQXA 1WCMD 1HUWA 1Y1VD 4BY1D 1F45B 3HOVD 1ALUA 4GC0A 3MZGA 3AYHA 3PO3D
chains in the Genus database with same CATH topology
3DLQI 1RHGA 1A7MA 1GNCA 4BXXD 1N1FA 4LRLA 5D28B 2Q7NB 4A3ED 1Z92A 1CN4C 2L3OA 5FLMD 1RCBA 2R92D 3NCFA 2IL6A 4NN5A 3UF5A 1HIJA 1WU3I 3QB7A 1ITFA 1ILKA 3EJJA 4ZS7A 1M47A 3PIVA 1PGRA 2B8UA 4MHLA 5D70A 1AXIA 1IK0A 3B5KA 4DOHA 3NPZA 4DKFA 1J7VL 1F6FA 3WCYI 5D72A 4EXNA 5FHXA 2D9QA 4A3CD 4ZF7A 1CD9A 3BPOA 3QWRB 1GA3A 4Z5RD 5KNHI 1SCFA 2Q98A 2ERJD 1IRLA 1HIKA 1YKBA 2B8XA 3D48P 1ETEA 1M48A 2O6IA 3LB6B 3SE3B 1CNT1 1BP3A 3FKID 3BESL 4NEJA 4YUEC 1LK3A 3L5WI 3HOWD 2GMFA 3DI3A 4A3GD 1ITIA 1EXZA 2JA5D 4NI9A 4DKEA 3G6DA 2Z3QA 1EMRA 3I4ND 3UX9A 3IRHA 4RS1A 3EW3A 4DKDA 3QAZA 1PVHB 3INKC 5C7XA 3S9DA 3BPLA 2PSMA 4A93D 1NBPA 1EERA 3UF2A 5IP9D 4DKCA 1IL6A 4FA8E 1RW5A 5D71A 2XQBA 3I4MD 5C4XD 1Y6NL 3NCBA 1A22A 3NCEA 3HOUD 1BBNA 2B63D 1KF9A 4I77Z 3TGXB 4A3KD 3NCCA 1V7MV 2CYKA 4NKQC 5IYBD 3OG6A 4NN6A 1HGUA 3PIWA 3N06A 1BGDA 1HZIA 1QVNA 4A3LD 1I1RB 4BY7D 1Y6KL 1AX8A 1CYLA 1AU1A 4A3MD 3HOYD 1M4CA 4A3BD 2INTA 2C35A 2LMSA 4YDYI 1HULA 1LKIA 2B90A 4NI7A 1CSGA 5C3ED 2D48A 1RFBA 3DUHC 1FG9A 3DI2A 4A3FD 1IJZA 1IARA 1V7NV 1Y6ML 5C44D 2Q14A 2R7ZD 1BGEA 1D9CA 2B8ZA 3H3VE 2ILKA 5D22A 5L6YC 4WRLB 3OG4A 3Q1SI 3N0PA 1FYHA 2O26A 1Z7CA 5IYDD 1JLIA 1PY2A 5E4EA 4X51A 3D85C 3DGCL 4GRWA 1D9GA 4NEMA 3UEZE 1BCNA 2OQPA 2R93D 1M49A 3D87A 3HHRA 4A3JD 3G9VB 1M4RA 3QT2C 4NN7A 1HWHA 1Y14A 4CNIC 1P9MB 1INRA 4EXPA 4BBSD 1PW6A 4GS7A 1BGCA 2LAGA 1B5LA 4PS4A 1ITMA 1Y1WD 4J4LC 4O9HA 5TS9A 3VA2A 3LB6A 4A3ID 2B8YA 3BPNA 4YPGC 3HHCA 2JA7D 1EKUA 3HOZD 1HWGA 1VLKA 2E9WC 2HYMB 2KZ1A 5FUCA 1ITLA 5IYCD 3PO2D 3OQ3A 3QB1A 1EVSA 1BUYA 3L5XA 3HOXD 2JA6D 4A3DD 2O27A 1LQSL 2JA8D 5IP7D 4BBRD 2H24A 4YQXA 1WCMD 1HUWA 1Y1VD 2B5IA 1F45B 5LQBA 4BY1D 2VUMD 3HOVD 1M4BA 2Z3RA 2L3YA 2B91A 1ALUA 3H0GD 3MZGA 3SE4B 3AYHA 3HMXB 3PO3D 1M4AA 4O6KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3B D;  2C35 A;  1Y1W D;  4BXX D;  3I4N D;  4A3I D;  4A3E D;  5FLM D;  2JA7 D;  2R92 D;  4A93 D;  5C3E D;  4A3F D;  3HOZ D;  5IP9 D;  4BBS D;  5C44 D;  2R7Z D;  5IYC D;  3I4M D;  3PO2 D;  5C4X D;  3HOU D;  3H3V E;  2B63 D;  3HOX D;  2JA6 D;  4A3D D;  2JA5 D;  4A3K D;  2JA8 D;  5IP7 D;  4BBR D;  3HOY D;  4A3C D;  1WCM D;  4BY1 D;  5IYB D;  1Y1V D;  2VUM D;  3HOV D;  3HOW D;  5IYD D;  4A3L D;  2R93 D;  3FKI D;  3H0G D;  4A3J D;  4BY7 D;  3PO3 D;  3AYH A;  4A3M D;  4A3G D;  1Y14 A; 
#chains in the Genus database with same CATH topology
 3DLQ I;  1Z92 A;  2L3O A;  1RCB A;  1HIJ A;  1WU3 I;  3QB7 A;  4IKX A;  1M47 A;  4PYP A;  4MHL A;  5D72 A;  1GA3 A;  1IRL A;  1HIK A;  3D48 P;  1ETE A;  1BP3 A;  2GMF A;  4NI9 A;  3G6D A;  1EMR A;  3IRH A;  5D58 A;  1PW4 A;  3QAZ A;  5C7X A;  4DKC A;  4UVM A;  1Y6N L;  2V8N A;  4A3K D;  5GXB A;  4TPJ A;  4A3L D;  1AU1 A;  1M4C A;  4A3B D;  4YDY I;  1CSG A;  5C3E D;  4LEP A;  1IJZ A;  1V7N V;  1FYH A;  2O26 A;  1Z7C A;  5EQI A;  3D85 C;  4U4W A;  4GRW A;  1D9G A;  2R93 D;  4A3J D;  1M49 A;  3D87 A;  3HHR A;  4OH3 A;  1M4R A;  1HWH A;  4CNI C;  1P9M B;  5TS9 A;  3LB6 A;  1EKU A;  1HWG A;  2E9W C;  5IYC D;  4JA3 A;  4YB9 D;  3QB1 A;  4A3D D;  2JA8 D;  4BBR D;  2VUM D;  2Z3R A;  1M4A A;  4O6K A;  1CN4 C;  1ITF A;  1ILK A;  4D2B A;  1PGR A;  5D6K A;  4IKW A;  1IK0 A;  4DKF A;  1F6F A;  1CD9 A;  2Q98 A;  1YKB A;  2O6I A;  1M48 A;  1CNT 1;  3DI3 A;  2JA5 D;  4DKE A;  3I4N D;  3S9D A;  3BPL A;  4A93 D;  1NBP A;  5IP9 D;  3NCB A;  3NCE A;  3HOU D;  1KF9 A;  3TGX B;  2CYK A;  1HGU A;  2Y5Y A;  4BY7 D;  1Y6K L;  1CYL A;  2LMS A;  4D2C A;  1HUL A;  2B90 A;  1RFB A;  4A3F D;  2B8Z A;  3H3V E;  4IKZ A;  5D22 A;  4Q65 A;  3N0P A;  5E4E A;  3UEZ E;  1BCN A;  3WDO A;  4ZWC A;  4EXP A;  4BBS D;  4TPG A;  1B5L A;  4PS4 A;  1ITM A;  4O9H A;  3VA2 A;  4J05 A;  5A2N A;  4GBY A;  2HYM B;  5FUC A;  3PO2 D;  1LQS L;  5IP7 D;  2H24 A;  2B5I A;  5LQB A;  2B91 A;  3H0G D;  3SE4 B;  3HOW D;  1GNC A;  5FLM D;  5EQG A;  3NCF A;  3EJJ A;  4U4V A;  4W6V A;  3NPZ A;  1J7V L;  3WCY I;  5FHX A;  4A3C D;  4ZF7 A;  3QWR B;  5KNH I;  3LB6 B;  4APS A;  3SE3 B;  3BES L;  4NEJ A;  4U4T A;  3L5W I;  1PVH B;  3INK C;  3UF2 A;  4ZYR A;  4FA8 E;  1RW5 A;  5D71 A;  5C4X D;  2B63 D;  3NCC A;  5IYB D;  3OG6 A;  3N06 A;  1BGD A;  1HZI A;  1QVN A;  4JRE A;  4A3M D;  3HOY D;  2INT A;  4JR9 A;  1LKI A;  4TPH A;  4NI7 A;  3DUH C;  1FG9 A;  5EQH A;  2R7Z D;  5L6Y C;  4WRL B;  3OG4 A;  3QT2 C;  4ZW9 A;  4NN7 A;  1Y14 A;  1PW6 A;  4J4L C;  3BPN A;  4YPG C;  3HHC A;  2JA7 D;  3HOZ D;  2KZ1 A;  3OQ3 A;  1BUY A;  2JA6 D;  4ZWB A;  1M4B A;  2L3Y A;  4GBZ A;  3HMX B;  1RHG A;  1A7M A;  4IKV A;  4BXX D;  1N1F A;  4LDS A;  4LRL A;  4XNI A;  5D28 B;  2Q7N B;  4A3E D;  2R92 D;  4NN5 A;  2IL6 A;  3UF5 A;  4QIQ A;  4ZS7 A;  3PIV A;  5D70 A;  2B8U A;  1AXI A;  3B5K A;  4IKY A;  4EXN A;  2D9Q A;  3BPO A;  4OAA A;  4Z5R D;  1SCF A;  4DOH A;  2ERJ D;  2B8X A;  3FKI D;  4YUE C;  1LK3 A;  1ITI A;  4A3G D;  1EXZ A;  2CFP A;  2Z3Q A;  3UX9 A;  2CFQ A;  4RS1 A;  3EW3 A;  3O7Q A;  4DKD A;  2PSM A;  1EER A;  3O7P A;  1IL6 A;  2XQB A;  1PV7 A;  3I4M D;  1A22 A;  1BBN A;  4YBQ A;  4I77 Z;  1V7M V;  4NKQ C;  4NN6 A;  3PIW A;  1I1R B;  1AX8 A;  5C65 A;  2XUT A;  4D2D A;  2C35 A;  2D48 A;  3DI2 A;  1IAR A;  5C44 D;  1Y6M L;  2Q14 A;  1BGE A;  4IU8 A;  1D9C A;  2ILK A;  3Q1S I;  4IU9 A;  5IYD D;  1JLI A;  1PY2 A;  4X51 A;  3DGC L;  4NEM A;  2OQP A;  5A2O A;  3G9V B;  1INR A;  4GS7 A;  1BGC A;  2LAG A;  1Y1W D;  4A3I D;  2B8Y A;  1PV6 A;  1VLK A;  4XNJ A;  1ITL A;  1EVS A;  3L5X A;  3HOX D;  2O27 A;  5D59 A;  4YQX A;  1WCM D;  1HUW A;  1Y1V D;  4BY1 D;  1F45 B;  3HOV D;  1ALU A;  4GC0 A;  3MZG A;  3AYH A;  3PO3 D; 
#chains in the Genus database with same CATH homology
 3DLQ I;  1RHG A;  1A7M A;  1GNC A;  4BXX D;  1N1F A;  4LRL A;  5D28 B;  2Q7N B;  4A3E D;  1Z92 A;  1CN4 C;  2L3O A;  5FLM D;  1RCB A;  2R92 D;  3NCF A;  2IL6 A;  4NN5 A;  3UF5 A;  1HIJ A;  1WU3 I;  3QB7 A;  1ITF A;  1ILK A;  3EJJ A;  4ZS7 A;  1M47 A;  3PIV A;  1PGR A;  2B8U A;  4MHL A;  5D70 A;  1AXI A;  1IK0 A;  3B5K A;  4DOH A;  3NPZ A;  4DKF A;  1J7V L;  1F6F A;  3WCY I;  5D72 A;  4EXN A;  5FHX A;  2D9Q A;  4A3C D;  4ZF7 A;  1CD9 A;  3BPO A;  3QWR B;  1GA3 A;  4Z5R D;  5KNH I;  1SCF A;  2Q98 A;  2ERJ D;  1IRL A;  1HIK A;  1YKB A;  2B8X A;  3D48 P;  1ETE A;  1M48 A;  2O6I A;  3LB6 B;  3SE3 B;  1CNT 1;  1BP3 A;  3FKI D;  3BES L;  4NEJ A;  4YUE C;  1LK3 A;  3L5W I;  3HOW D;  2GMF A;  3DI3 A;  4A3G D;  1ITI A;  1EXZ A;  2JA5 D;  4NI9 A;  4DKE A;  3G6D A;  2Z3Q A;  1EMR A;  3I4N D;  3UX9 A;  3IRH A;  4RS1 A;  3EW3 A;  4DKD A;  3QAZ A;  1PVH B;  3INK C;  5C7X A;  3S9D A;  3BPL A;  2PSM A;  4A93 D;  1NBP A;  1EER A;  3UF2 A;  5IP9 D;  4DKC A;  1IL6 A;  4FA8 E;  1RW5 A;  5D71 A;  2XQB A;  3I4M D;  5C4X D;  1Y6N L;  3NCB A;  1A22 A;  3NCE A;  3HOU D;  1BBN A;  2B63 D;  1KF9 A;  4I77 Z;  3TGX B;  4A3K D;  3NCC A;  1V7M V;  2CYK A;  4NKQ C;  5IYB D;  3OG6 A;  4NN6 A;  1HGU A;  3PIW A;  3N06 A;  1BGD A;  1HZI A;  1QVN A;  4A3L D;  1I1R B;  4BY7 D;  1Y6K L;  1AX8 A;  1CYL A;  1AU1 A;  4A3M D;  3HOY D;  1M4C A;  4A3B D;  2INT A;  2C35 A;  2LMS A;  4YDY I;  1HUL A;  1LKI A;  2B90 A;  4NI7 A;  1CSG A;  5C3E D;  2D48 A;  1RFB A;  3DUH C;  1FG9 A;  3DI2 A;  4A3F D;  1IJZ A;  1IAR A;  1V7N V;  1Y6M L;  5C44 D;  2Q14 A;  2R7Z D;  1BGE A;  1D9C A;  2B8Z A;  3H3V E;  2ILK A;  5D22 A;  5L6Y C;  4WRL B;  3OG4 A;  3Q1S I;  3N0P A;  1FYH A;  2O26 A;  1Z7C A;  5IYD D;  1JLI A;  1PY2 A;  5E4E A;  4X51 A;  3D85 C;  3DGC L;  4GRW A;  1D9G A;  4NEM A;  3UEZ E;  1BCN A;  2OQP A;  2R93 D;  1M49 A;  3D87 A;  3HHR A;  4A3J D;  3G9V B;  1M4R A;  3QT2 C;  4NN7 A;  1HWH A;  1Y14 A;  4CNI C;  1P9M B;  1INR A;  4EXP A;  4BBS D;  1PW6 A;  4GS7 A;  1BGC A;  2LAG A;  1B5L A;  4PS4 A;  1ITM A;  1Y1W D;  4J4L C;  4O9H A;  5TS9 A;  3VA2 A;  3LB6 A;  4A3I D;  2B8Y A;  3BPN A;  4YPG C;  3HHC A;  2JA7 D;  1EKU A;  3HOZ D;  1HWG A;  1VLK A;  2E9W C;  2HYM B;  2KZ1 A;  5FUC A;  1ITL A;  5IYC D;  3PO2 D;  3OQ3 A;  3QB1 A;  1EVS A;  1BUY A;  3L5X A;  3HOX D;  2JA6 D;  4A3D D;  2O27 A;  1LQS L;  2JA8 D;  5IP7 D;  4BBR D;  2H24 A;  4YQX A;  1WCM D;  1HUW A;  1Y1V D;  2B5I A;  1F45 B;  5LQB A;  4BY1 D;  2VUM D;  3HOV D;  1M4B A;  2Z3R A;  2L3Y A;  2B91 A;  1ALU A;  3H0G D;  3MZG A;  3SE4 B;  3AYH A;  3HMX B;  3PO3 D;  1M4A A;  4O6K A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...