2IW4A

Crystal structure of basillus subtilis family ii inorganic pyrophosphatase mutant, h98q, in complex with pnp
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
307
structure length
307
Chain Sequence
EKILIFGHQNPDTDTICSAIAYADLKNKLGFNAEPVRLGQVNGETQYALDYFKQESPRLVETAANEVNGVILVDHNERQQSIKDIEEVQVLEVIDHQRIANFETAEPLYYRAEPVGCTATILNKMYKENNVKIEKEIAGLMLSAIISDSLLFKSPTCTDQDVAAAKELAEIAGVDAEEYGLNMLKAGADLSKKTVEELISLDAKEFTLGSKKVEIAQVNTVDIEDVKKRQAELEAVISKVVAEKNLDLFLLVITDILENDSLALAIGNEAAKVEKAFNVTLENNTALLKGVVSRKKQVVPVLTDAMA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Trimetal Site and Substrate Distortion in a Family II Inorganic Pyrophosphatase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Bacillus subtilis
molecule keywords MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE
total genus 110
structure length 307
sequence length 307
chains with identical sequence B
ec nomenclature ec 3.6.1.1: Inorganic diphosphatase.
pdb deposition date 2006-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01368 DHH DHH family
A PF02833 DHHA2 DHHA2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.310.20 Alpha Beta Roll Diaminopimelate Epimerase; Chain A, domain 1 Diaminopimelate Epimerase; Chain A, domain 1 2iw4A02
3.90.1640.10 Alpha Beta Alpha-Beta Complex inorganic pyrophosphatase (n-terminal core) inorganic pyrophosphatase (n-terminal core) 2iw4A01
3W5WA 2QB7A 4RPAA 2QB8A 2HAWA 2IW4A 3DEVA 1I74A 2EB0A 1WPPA 2QB6A 1WPNA 1K20A 1WPMA 2ENXA 1K23A 4LS9A 4PY9A
chains in the Genus database with same CATH superfamily
2HAWA 1BWZA 1W61A 4Q2HA 1SDJA 3FVEA 3ICJA 1U1WA 2ZXRA 4PY9A 2GKEA 2QB7A 2PVZA 2ZVFA 4LB0A 2ZXOA 4K7XA 4OA3A 1T6KA 1K20A 2ENXA 5GL3A 1S7JA 3G98A 4IJZA 4J9XA 2QB8A 2IW4A 2OTNA 4Q60A 5H2YA 1XUAA 1YM5A 3EDNA 3W5WA 1XUBA 4K7GB 1QY9A 2ZXPA 5IWEA 4J9WA 4FC5A 4LG3A 3EJXA 1U0KA 2EB0A 3PW9A 1WPNA 1WPMA 1K23A 1QYAA 2KW7A 4RPAA 5M47A 1TM0A 1GQZA 2PW0A 5GKXA 2QB6A 5H2GA 2YMAA 1U1XA 5GL4A 1W62A 3PVHA 3PTJA 4LS9A 2MPBA 2GKJA 2LT2A 5ANPA 4DUNA 3IGHX 1I74A 3EKMA 4DWZA 4JD7A 3WQZA 4JUUA 2KPTA 2Q9JA 5HA4A 1WPPA 4JBDA 4GL6A 3G7KA 2H9FA 3DEVA 4IK0A 1U1VA 5GL2A 2Q9HA 4K8LA 4JCIA 1IR6A 2AZPA
chains in the Genus database with same CATH topology
2HAWA 1BWZA 1W61A 4Q2HA 1SDJA 3FVEA 3ICJA 1U1WA 2ZXRA 4PY9A 2GKEA 2QB7A 2PVZA 2ZVFA 4LB0A 2ZXOA 4K7XA 4OA3A 1T6KA 1K20A 2ENXA 5GL3A 1S7JA 3G98A 4IJZA 4J9XA 2QB8A 2IW4A 2OTNA 4Q60A 5H2YA 1XUAA 1YM5A 3EDNA 3W5WA 1XUBA 4K7GB 1QY9A 2ZXPA 5IWEA 4J9WA 4FC5A 4LG3A 3EJXA 1U0KA 2EB0A 3PW9A 1WPNA 1WPMA 1K23A 1QYAA 2KW7A 4RPAA 5M47A 1TM0A 1GQZA 2PW0A 5GKXA 2QB6A 5H2GA 2YMAA 1U1XA 5GL4A 1W62A 3PVHA 3PTJA 4LS9A 2MPBA 2GKJA 2LT2A 5ANPA 4DUNA 3IGHX 1I74A 3EKMA 4DWZA 4JD7A 3WQZA 4JUUA 2KPTA 2Q9JA 5HA4A 1WPPA 4JBDA 4GL6A 3G7KA 2H9FA 3DEVA 4IK0A 1U1VA 5GL2A 2Q9HA 4K8LA 4JCIA 1IR6A 2AZPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W5W A;  2QB7 A;  4RPA A;  2QB8 A;  2HAW A;  2IW4 A;  3DEV A;  1I74 A;  2EB0 A;  1WPP A;  2QB6 A;  1WPN A;  1K20 A;  1WPM A;  2ENX A;  1K23 A;  4LS9 A;  4PY9 A; 
#chains in the Genus database with same CATH topology
 2HAW A;  1BWZ A;  1W61 A;  4Q2H A;  1SDJ A;  3FVE A;  3ICJ A;  1U1W A;  2ZXR A;  4PY9 A;  2GKE A;  2QB7 A;  2PVZ A;  2ZVF A;  4LB0 A;  2ZXO A;  4K7X A;  4OA3 A;  1T6K A;  1K20 A;  2ENX A;  5GL3 A;  1S7J A;  3G98 A;  4IJZ A;  4J9X A;  2QB8 A;  2IW4 A;  2OTN A;  4Q60 A;  5H2Y A;  1XUA A;  1YM5 A;  3EDN A;  3W5W A;  1XUB A;  4K7G B;  1QY9 A;  2ZXP A;  5IWE A;  4J9W A;  4FC5 A;  4LG3 A;  3EJX A;  1U0K A;  2EB0 A;  3PW9 A;  1WPN A;  1WPM A;  1K23 A;  1QYA A;  2KW7 A;  4RPA A;  5M47 A;  1TM0 A;  1GQZ A;  2PW0 A;  5GKX A;  2QB6 A;  5H2G A;  2YMA A;  1U1X A;  5GL4 A;  1W62 A;  3PVH A;  3PTJ A;  4LS9 A;  2MPB A;  2GKJ A;  2LT2 A;  5ANP A;  4DUN A;  3IGH X;  1I74 A;  3EKM A;  4DWZ A;  4JD7 A;  3WQZ A;  4JUU A;  2KPT A;  2Q9J A;  5HA4 A;  1WPP A;  4JBD A;  4GL6 A;  3G7K A;  2H9F A;  3DEV A;  4IK0 A;  1U1V A;  5GL2 A;  2Q9H A;  4K8L A;  4JCI A;  1IR6 A;  2AZP A; 
#chains in the Genus database with same CATH homology
 2HAW A;  1BWZ A;  1W61 A;  4Q2H A;  1SDJ A;  3FVE A;  3ICJ A;  1U1W A;  2ZXR A;  4PY9 A;  2GKE A;  2QB7 A;  2PVZ A;  2ZVF A;  4LB0 A;  2ZXO A;  4K7X A;  4OA3 A;  1T6K A;  1K20 A;  2ENX A;  5GL3 A;  1S7J A;  3G98 A;  4IJZ A;  4J9X A;  2QB8 A;  2IW4 A;  2OTN A;  4Q60 A;  5H2Y A;  1XUA A;  1YM5 A;  3EDN A;  3W5W A;  1XUB A;  4K7G B;  1QY9 A;  2ZXP A;  5IWE A;  4J9W A;  4FC5 A;  4LG3 A;  3EJX A;  1U0K A;  2EB0 A;  3PW9 A;  1WPN A;  1WPM A;  1K23 A;  1QYA A;  2KW7 A;  4RPA A;  5M47 A;  1TM0 A;  1GQZ A;  2PW0 A;  5GKX A;  2QB6 A;  5H2G A;  2YMA A;  1U1X A;  5GL4 A;  1W62 A;  3PVH A;  3PTJ A;  4LS9 A;  2MPB A;  2GKJ A;  2LT2 A;  5ANP A;  4DUN A;  3IGH X;  1I74 A;  3EKM A;  4DWZ A;  4JD7 A;  3WQZ A;  4JUU A;  2KPT A;  2Q9J A;  5HA4 A;  1WPP A;  4JBD A;  4GL6 A;  3G7K A;  2H9F A;  3DEV A;  4IK0 A;  1U1V A;  5GL2 A;  2Q9H A;  4K8L A;  4JCI A;  1IR6 A;  2AZP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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