3AEAD

Crystal structure of porcine heart mitochondrial complex ii bound with n-(3-dimethylaminomethyl-phenyl)-2-trifluoromethyl-benzamide
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
102
structure length
102
Chain Sequence
SSKAASLHWTGERVVSVLLLGLLPAAYLNPCSAMDYSLAAALTLHGHWGIGQVVTDYVRGDALQKAAKAGLLALSAFTFAGLCYFNYHDVGICKAVAMLWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase [ubiquinone] flavoprotein subunit, m
total genus 38
structure length 102
sequence length 102
ec nomenclature
pdb deposition date 2010-02-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 3aeaD00
1NEKC 4YTPC 1L0VC 2B76D 3P4PC 2H89D 2B76C 4YT0D 2H88D 4YXDC 4YT0C 2H88C 1NEND 4KX6D 1NENC 4YTND 4KX6C 3AE6D 4YTNC 5C2TD 1ZOYD 3AE6C 3AE9D 5C2TC 2WDRD 4YSZD 2ACZD 2WS3D 1ZOYC 3AE9C 2WDRC 4YSZC 2ACZC 5C3JD 1YQ4D 2WS3C 2BS4C 3AEFD 4YTMD 5C3JC 1YQ4C 3AE1D 3AEFC 3CIRD 3P4SD 4YTMC 2H89C 3VRAD 4YSYD 3AE1C 4YSXD 3CIRC 3P4SC 3AE4D 3AEAD 3VRAC 1KF6D 3VRBD 4YSYC 4YSXC 3AEAC 1QLBC 1KF6C 3AEGD 2WU5D 3AEGC 3P4RD 2WU5C 3AE5D 3AEED 3P4RC 3AEDD 3AE5C 3AEEC 2BS3C 3AE7D 2WP9D 3VR8D 3AE7C 2WP9C 3VR9D 3VR8C 1YQ3D 3VR9C 2WQYD 3AE4C 3SFDD 1YQ3C 3VRBC 1NEKD 2WQYC 3SFDC 3P4PD 1KFYD 3AE3D 2WDVD 4YXDD 1KFYC 3AE3C 2WDVC 3P4QD 2BS2C 3AECD 2FBWD 3P4QC 3AEDC 3AECC 3ABVD 1E7PC 2FBWC 3AE2D 3ABVC 2WU2D 3SFED 3AE8D 2WDQD 3AEBD 3AE2C 1ZP0D 3SFEC 2WU2C 3AE8C 2WDQC 3AEBC 1ZP0C 4YTPD 1L0VD
chains in the Genus database with same CATH superfamily
1TFFA 1NEKC 4YTPC 1L0VC 2B76D 4DHIB 3P4PC 2H89D 4I6LA 2B76C 4YT0D 2H88D 4DHZA 4YXDC 4YT0C 2H88C 1NEND 4KX6D 1NENC 4YTND 4KX6C 3AE6D 4YTNC 5C2TD 1ZOYD 3AE6C 3AE9D 5C2TC 2WDRD 4YSZD 2ACZD 2WS3D 1ZOYC 3AE9C 2WDRC 4YSZC 2ACZC 5C3JD 1YQ4D 2WS3C 2BS4C 3AEFD 4YTMD 5C3JC 1YQ4C 3AE1D 3AEFC 3CIRD 3P4SD 4YTMC 2H89C 3VRAD 4YSYD 3AE1C 4YSXD 3CIRC 3P4SC 3AE4D 3AEAD 3VRAC 1KF6D 3VRBD 4YSYC 4YSXC 3AEAC 1QLBC 1KF6C 3AEGD 4FJVA 2WU5D 3AEGC 3P4RD 2WU5C 4DDGA 3AE5D 3AEED 3P4RC 3AEDD 3AE5C 3AEEC 2BS3C 3AE7D 2WP9D 3VR8D 3AE7C 2WP9C 3VR9D 3VR8C 1YQ3D 4DHJA 4DDIA 3VR9C 2WQYD 3AE4C 3VONA 3SFDD 1YQ3C 3VRBC 1NEKD 2WQYC 3SFDC 3P4PD 1KFYD 3AE3D 2WDVD 2ZFYA 4YXDD 1KFYC 3AE3C 2WDVC 3P4QD 2BS2C 3AECD 2FBWD 3P4QC 3AEDC 4LDTA 3AECC 3ABVD 1E7PC 2FBWC 3AE2D 3ABVC 2WU2D 3SFED 3AE8D 2WDQD 3AEBD 3AE2C 1ZP0D 3SFEC 2WU2C 3AE8C 2WDQC 3AEBC 1ZP0C 4YTPD 1L0VD
chains in the Genus database with same CATH topology
1NEKC 4YTPC 1L0VC 2B76D 3P4PC 2H89D 2B76C 4YT0D 2H88D 4YXDC 4YT0C 2H88C 1NEND 4KX6D 1NENC 4YTND 4KX6C 3AE6D 4YTNC 5C2TD 1ZOYD 3AE6C 3AE9D 5C2TC 2WDRD 4YSZD 2ACZD 2WS3D 1ZOYC 3AE9C 2WDRC 4YSZC 2ACZC 5C3JD 1YQ4D 2WS3C 2BS4C 3AEFD 4YTMD 5C3JC 1YQ4C 3AE1D 3AEFC 3CIRD 3P4SD 4YTMC 2H89C 3VRAD 4YSYD 3AE1C 4YSXD 3CIRC 3P4SC 3AE4D 3AEAD 3VRAC 1KF6D 3VRBD 4YSYC 4YSXC 3AEAC 1QLBC 1KF6C 3AEGD 2WU5D 3AEGC 3P4RD 2WU5C 3AE5D 3AEED 3P4RC 3AEDD 3AE5C 3AEEC 2BS3C 3AE7D 2WP9D 3VR8D 3AE7C 2WP9C 3VR9D 3VR8C 1YQ3D 3VR9C 2WQYD 3AE4C 3SFDD 1YQ3C 3VRBC 1NEKD 2WQYC 3SFDC 3P4PD 1KFYD 3AE3D 2WDVD 4YXDD 1KFYC 3AE3C 2WDVC 3P4QD 2BS2C 3AECD 2FBWD 3P4QC 3AEDC 3AECC 3ABVD 1E7PC 2FBWC 3AE2D 3ABVC 2WU2D 3SFED 3AE8D 2WDQD 3AEBD 3AE2C 1ZP0D 3SFEC 2WU2C 3AE8C 2WDQC 3AEBC 1ZP0C 4YTPD 1L0VD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NEK C;  4YTP C;  1L0V C;  2B76 D;  3P4P C;  2H89 D;  2B76 C;  4YT0 D;  2H88 D;  4YXD C;  4YT0 C;  2H88 C;  1NEN D;  4KX6 D;  1NEN C;  4YTN D;  4KX6 C;  3AE6 D;  4YTN C;  5C2T D;  1ZOY D;  3AE6 C;  3AE9 D;  5C2T C;  2WDR D;  4YSZ D;  2ACZ D;  2WS3 D;  1ZOY C;  3AE9 C;  2WDR C;  4YSZ C;  2ACZ C;  5C3J D;  1YQ4 D;  2WS3 C;  2BS4 C;  3AEF D;  4YTM D;  5C3J C;  1YQ4 C;  3AE1 D;  3AEF C;  3CIR D;  3P4S D;  4YTM C;  2H89 C;  3VRA D;  4YSY D;  3AE1 C;  4YSX D;  3CIR C;  3P4S C;  3AE4 D;  3AEA D;  3VRA C;  1KF6 D;  3VRB D;  4YSY C;  4YSX C;  3AEA C;  1QLB C;  1KF6 C;  3AEG D;  2WU5 D;  3AEG C;  3P4R D;  2WU5 C;  3AE5 D;  3AEE D;  3P4R C;  3AED D;  3AE5 C;  3AEE C;  2BS3 C;  3AE7 D;  2WP9 D;  3VR8 D;  3AE7 C;  2WP9 C;  3VR9 D;  3VR8 C;  1YQ3 D;  3VR9 C;  2WQY D;  3AE4 C;  3SFD D;  1YQ3 C;  3VRB C;  1NEK D;  2WQY C;  3SFD C;  3P4P D;  1KFY D;  3AE3 D;  2WDV D;  4YXD D;  1KFY C;  3AE3 C;  2WDV C;  3P4Q D;  2BS2 C;  3AEC D;  2FBW D;  3P4Q C;  3AED C;  3AEC C;  3ABV D;  1E7P C;  2FBW C;  3AE2 D;  3ABV C;  2WU2 D;  3SFE D;  3AE8 D;  2WDQ D;  3AEB D;  3AE2 C;  1ZP0 D;  3SFE C;  2WU2 C;  3AE8 C;  2WDQ C;  3AEB C;  1ZP0 C;  4YTP D;  1L0V D; 
#chains in the Genus database with same CATH topology
 1TFF A;  1NEK C;  4YTP C;  1L0V C;  2B76 D;  4DHI B;  3P4P C;  2H89 D;  4I6L A;  2B76 C;  4YT0 D;  2H88 D;  4DHZ A;  4YXD C;  4YT0 C;  2H88 C;  1NEN D;  4KX6 D;  1NEN C;  4YTN D;  4KX6 C;  3AE6 D;  4YTN C;  5C2T D;  1ZOY D;  3AE6 C;  3AE9 D;  5C2T C;  2WDR D;  4YSZ D;  2ACZ D;  2WS3 D;  1ZOY C;  3AE9 C;  2WDR C;  4YSZ C;  2ACZ C;  5C3J D;  1YQ4 D;  2WS3 C;  2BS4 C;  3AEF D;  4YTM D;  5C3J C;  1YQ4 C;  3AE1 D;  3AEF C;  3CIR D;  3P4S D;  4YTM C;  2H89 C;  3VRA D;  4YSY D;  3AE1 C;  4YSX D;  3CIR C;  3P4S C;  3AE4 D;  3AEA D;  3VRA C;  1KF6 D;  3VRB D;  4YSY C;  4YSX C;  3AEA C;  1QLB C;  1KF6 C;  3AEG D;  4FJV A;  2WU5 D;  3AEG C;  3P4R D;  2WU5 C;  4DDG A;  3AE5 D;  3AEE D;  3P4R C;  3AED D;  3AE5 C;  3AEE C;  2BS3 C;  3AE7 D;  2WP9 D;  3VR8 D;  3AE7 C;  2WP9 C;  3VR9 D;  3VR8 C;  1YQ3 D;  4DHJ A;  4DDI A;  3VR9 C;  2WQY D;  3AE4 C;  3VON A;  3SFD D;  1YQ3 C;  3VRB C;  1NEK D;  2WQY C;  3SFD C;  3P4P D;  1KFY D;  3AE3 D;  2WDV D;  2ZFY A;  4YXD D;  1KFY C;  3AE3 C;  2WDV C;  3P4Q D;  2BS2 C;  3AEC D;  2FBW D;  3P4Q C;  3AED C;  4LDT A;  3AEC C;  3ABV D;  1E7P C;  2FBW C;  3AE2 D;  3ABV C;  2WU2 D;  3SFE D;  3AE8 D;  2WDQ D;  3AEB D;  3AE2 C;  1ZP0 D;  3SFE C;  2WU2 C;  3AE8 C;  2WDQ C;  3AEB C;  1ZP0 C;  4YTP D;  1L0V D; 
#chains in the Genus database with same CATH homology
 1NEK C;  4YTP C;  1L0V C;  2B76 D;  3P4P C;  2H89 D;  2B76 C;  4YT0 D;  2H88 D;  4YXD C;  4YT0 C;  2H88 C;  1NEN D;  4KX6 D;  1NEN C;  4YTN D;  4KX6 C;  3AE6 D;  4YTN C;  5C2T D;  1ZOY D;  3AE6 C;  3AE9 D;  5C2T C;  2WDR D;  4YSZ D;  2ACZ D;  2WS3 D;  1ZOY C;  3AE9 C;  2WDR C;  4YSZ C;  2ACZ C;  5C3J D;  1YQ4 D;  2WS3 C;  2BS4 C;  3AEF D;  4YTM D;  5C3J C;  1YQ4 C;  3AE1 D;  3AEF C;  3CIR D;  3P4S D;  4YTM C;  2H89 C;  3VRA D;  4YSY D;  3AE1 C;  4YSX D;  3CIR C;  3P4S C;  3AE4 D;  3AEA D;  3VRA C;  1KF6 D;  3VRB D;  4YSY C;  4YSX C;  3AEA C;  1QLB C;  1KF6 C;  3AEG D;  2WU5 D;  3AEG C;  3P4R D;  2WU5 C;  3AE5 D;  3AEE D;  3P4R C;  3AED D;  3AE5 C;  3AEE C;  2BS3 C;  3AE7 D;  2WP9 D;  3VR8 D;  3AE7 C;  2WP9 C;  3VR9 D;  3VR8 C;  1YQ3 D;  3VR9 C;  2WQY D;  3AE4 C;  3SFD D;  1YQ3 C;  3VRB C;  1NEK D;  2WQY C;  3SFD C;  3P4P D;  1KFY D;  3AE3 D;  2WDV D;  4YXD D;  1KFY C;  3AE3 C;  2WDV C;  3P4Q D;  2BS2 C;  3AEC D;  2FBW D;  3P4Q C;  3AED C;  3AEC C;  3ABV D;  1E7P C;  2FBW C;  3AE2 D;  3ABV C;  2WU2 D;  3SFE D;  3AE8 D;  2WDQ D;  3AEB D;  3AE2 C;  1ZP0 D;  3SFE C;  2WU2 C;  3AE8 C;  2WDQ C;  3AEB C;  1ZP0 C;  4YTP D;  1L0V D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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