3P4SC

Crystal structure of menaquinol:fumarate oxidoreductase in complex with a 3-nitropropionate adduct
Total Genus 40
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
130
structure length
130
Chain Sequence
TTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli 042
molecule keywords Fumarate reductase flavoprotein subunit
total genus 40
structure length 130
sequence length 130
chains with identical sequence O
ec nomenclature
pdb deposition date 2010-10-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF02300 Fumarate_red_C Fumarate reductase subunit C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 3p4sC00
1KF6C 2WQYC 1KF6D 2WQYD 1YQ3C 3AE7C 1YQ3D 3AE7D 3AE6C 1QLBC 3AE5D 3VR8C 3AE3C 3AE6D 3VR8D 3AE3D 2BS2C 2WU2C 1NENC 3AE1C 4YSXC 2WU2D 1NEND 3AE1D 4YSXD 1L0VC 1NEKC 4YT0C 1L0VD 1NEKD 4YT0D 1ZOYC 2BS4C 2ACZC 3AEEC 1ZOYD 2ACZD 3AEED 3P4QC 4YSYC 3VRBC 3AEAC 3P4QD 4YSYD 3VRBD 3AEAD 3ABVC 2H89C 3P4PC 3ABVD 2H89D 3P4PD 1ZP0C 4YSZC 1ZP0D 4YSZD 5C2TC 5C2TD 3AE5C 3AE9C 3AECC 3AE9D 3AECD 2WS3C 4YXDC 2WS3D 4YXDD 3AE4C 3AE4D 2WU5C 2WU5D 3SFEC 3SFED 4KX6C 1KFYC 4KX6D 1KFYD 3AEDC 2FBWC 3AEDD 2WDVC 2FBWD 3P4SC 2WDVD 3AEFC 3AEGC 3P4SD 3AEFD 3AEGD 3VRAC 3VRAD 2B76C 2H88C 2B76D 2H88D 4YTPC 3SFDC 2BS3C 4YTPD 3SFDD 3AE8C 2WDQC 3CIRC 3AE8D 2WDQD 3CIRD 4YTMC 4YTMD 1YQ4C 3VR9C 1YQ4D 3VR9D 2WDRC 1E7PC 2WDRD 4YTNC 5C3JC 3AE2C 5C3JD 4YTND 3P4RC 3AE2D 2WP9C 3P4RD 3AEBC 2WP9D 3AEBD
chains in the Genus database with same CATH superfamily
1KF6C 2WQYC 1KF6D 2WQYD 3VONA 1YQ3C 3AE7C 4I6LA 1YQ3D 3AE7D 3AE6C 1QLBC 3AE5D 3VR8C 3AE3C 3AE6D 3VR8D 3AE3D 2BS2C 4DHJA 2WU2C 1NENC 3AE1C 4YSXC 2WU2D 1NEND 3AE1D 4YSXD 1L0VC 1NEKC 4LDTA 1TFFA 4YT0C 1L0VD 1NEKD 4YT0D 1ZOYC 2BS4C 2ACZC 3AEEC 1ZOYD 2ACZD 3AEED 3P4QC 4YSYC 3VRBC 3AEAC 3P4QD 4YSYD 3VRBD 3AEAD 3ABVC 2H89C 3P4PC 3ABVD 2H89D 3P4PD 1ZP0C 4YSZC 1ZP0D 4YSZD 5C2TC 5C2TD 3AE5C 3AE9C 3AECC 3AE9D 4FJVA 3AECD 2WS3C 4YXDC 2WS3D 4YXDD 3AE4C 3AE4D 2WU5C 2WU5D 3SFEC 3SFED 4KX6C 1KFYC 4KX6D 1KFYD 3AEDC 2FBWC 3AEDD 2WDVC 2FBWD 3P4SC 2WDVD 3AEFC 3AEGC 3P4SD 3AEFD 3AEGD 3VRAC 4DHIB 3VRAD 2B76C 2H88C 2B76D 2H88D 2ZFYA 4YTPC 3SFDC 2BS3C 4YTPD 3SFDD 3AE8C 2WDQC 4DDGA 3CIRC 3AE8D 2WDQD 3CIRD 4YTMC 4YTMD 1YQ4C 3VR9C 1YQ4D 4DHZA 3VR9D 2WDRC 1E7PC 2WDRD 4YTNC 5C3JC 3AE2C 5C3JD 4YTND 3P4RC 3AE2D 2WP9C 3P4RD 3AEBC 2WP9D 3AEBD 4DDIA
chains in the Genus database with same CATH topology
1KF6C 2WQYC 1KF6D 2WQYD 1YQ3C 3AE7C 1YQ3D 3AE7D 3AE6C 1QLBC 3AE5D 3VR8C 3AE3C 3AE6D 3VR8D 3AE3D 2BS2C 2WU2C 1NENC 3AE1C 4YSXC 2WU2D 1NEND 3AE1D 4YSXD 1L0VC 1NEKC 4YT0C 1L0VD 1NEKD 4YT0D 1ZOYC 2BS4C 2ACZC 3AEEC 1ZOYD 2ACZD 3AEED 3P4QC 4YSYC 3VRBC 3AEAC 3P4QD 4YSYD 3VRBD 3AEAD 3ABVC 2H89C 3P4PC 3ABVD 2H89D 3P4PD 1ZP0C 4YSZC 1ZP0D 4YSZD 5C2TC 5C2TD 3AE5C 3AE9C 3AECC 3AE9D 3AECD 2WS3C 4YXDC 2WS3D 4YXDD 3AE4C 3AE4D 2WU5C 2WU5D 3SFEC 3SFED 4KX6C 1KFYC 4KX6D 1KFYD 3AEDC 2FBWC 3AEDD 2WDVC 2FBWD 3P4SC 2WDVD 3AEFC 3AEGC 3P4SD 3AEFD 3AEGD 3VRAC 3VRAD 2B76C 2H88C 2B76D 2H88D 4YTPC 3SFDC 2BS3C 4YTPD 3SFDD 3AE8C 2WDQC 3CIRC 3AE8D 2WDQD 3CIRD 4YTMC 4YTMD 1YQ4C 3VR9C 1YQ4D 3VR9D 2WDRC 1E7PC 2WDRD 4YTNC 5C3JC 3AE2C 5C3JD 4YTND 3P4RC 3AE2D 2WP9C 3P4RD 3AEBC 2WP9D 3AEBD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KF6 C;  2WQY C;  1KF6 D;  2WQY D;  1YQ3 C;  3AE7 C;  1YQ3 D;  3AE7 D;  3AE6 C;  1QLB C;  3AE5 D;  3VR8 C;  3AE3 C;  3AE6 D;  3VR8 D;  3AE3 D;  2BS2 C;  2WU2 C;  1NEN C;  3AE1 C;  4YSX C;  2WU2 D;  1NEN D;  3AE1 D;  4YSX D;  1L0V C;  1NEK C;  4YT0 C;  1L0V D;  1NEK D;  4YT0 D;  1ZOY C;  2BS4 C;  2ACZ C;  3AEE C;  1ZOY D;  2ACZ D;  3AEE D;  3P4Q C;  4YSY C;  3VRB C;  3AEA C;  3P4Q D;  4YSY D;  3VRB D;  3AEA D;  3ABV C;  2H89 C;  3P4P C;  3ABV D;  2H89 D;  3P4P D;  1ZP0 C;  4YSZ C;  1ZP0 D;  4YSZ D;  5C2T C;  5C2T D;  3AE5 C;  3AE9 C;  3AEC C;  3AE9 D;  3AEC D;  2WS3 C;  4YXD C;  2WS3 D;  4YXD D;  3AE4 C;  3AE4 D;  2WU5 C;  2WU5 D;  3SFE C;  3SFE D;  4KX6 C;  1KFY C;  4KX6 D;  1KFY D;  3AED C;  2FBW C;  3AED D;  2WDV C;  2FBW D;  3P4S C;  2WDV D;  3AEF C;  3AEG C;  3P4S D;  3AEF D;  3AEG D;  3VRA C;  3VRA D;  2B76 C;  2H88 C;  2B76 D;  2H88 D;  4YTP C;  3SFD C;  2BS3 C;  4YTP D;  3SFD D;  3AE8 C;  2WDQ C;  3CIR C;  3AE8 D;  2WDQ D;  3CIR D;  4YTM C;  4YTM D;  1YQ4 C;  3VR9 C;  1YQ4 D;  3VR9 D;  2WDR C;  1E7P C;  2WDR D;  4YTN C;  5C3J C;  3AE2 C;  5C3J D;  4YTN D;  3P4R C;  3AE2 D;  2WP9 C;  3P4R D;  3AEB C;  2WP9 D;  3AEB D; 
#chains in the Genus database with same CATH topology
 1KF6 C;  2WQY C;  1KF6 D;  2WQY D;  3VON A;  1YQ3 C;  3AE7 C;  4I6L A;  1YQ3 D;  3AE7 D;  3AE6 C;  1QLB C;  3AE5 D;  3VR8 C;  3AE3 C;  3AE6 D;  3VR8 D;  3AE3 D;  2BS2 C;  4DHJ A;  2WU2 C;  1NEN C;  3AE1 C;  4YSX C;  2WU2 D;  1NEN D;  3AE1 D;  4YSX D;  1L0V C;  1NEK C;  4LDT A;  1TFF A;  4YT0 C;  1L0V D;  1NEK D;  4YT0 D;  1ZOY C;  2BS4 C;  2ACZ C;  3AEE C;  1ZOY D;  2ACZ D;  3AEE D;  3P4Q C;  4YSY C;  3VRB C;  3AEA C;  3P4Q D;  4YSY D;  3VRB D;  3AEA D;  3ABV C;  2H89 C;  3P4P C;  3ABV D;  2H89 D;  3P4P D;  1ZP0 C;  4YSZ C;  1ZP0 D;  4YSZ D;  5C2T C;  5C2T D;  3AE5 C;  3AE9 C;  3AEC C;  3AE9 D;  4FJV A;  3AEC D;  2WS3 C;  4YXD C;  2WS3 D;  4YXD D;  3AE4 C;  3AE4 D;  2WU5 C;  2WU5 D;  3SFE C;  3SFE D;  4KX6 C;  1KFY C;  4KX6 D;  1KFY D;  3AED C;  2FBW C;  3AED D;  2WDV C;  2FBW D;  3P4S C;  2WDV D;  3AEF C;  3AEG C;  3P4S D;  3AEF D;  3AEG D;  3VRA C;  4DHI B;  3VRA D;  2B76 C;  2H88 C;  2B76 D;  2H88 D;  2ZFY A;  4YTP C;  3SFD C;  2BS3 C;  4YTP D;  3SFD D;  3AE8 C;  2WDQ C;  4DDG A;  3CIR C;  3AE8 D;  2WDQ D;  3CIR D;  4YTM C;  4YTM D;  1YQ4 C;  3VR9 C;  1YQ4 D;  4DHZ A;  3VR9 D;  2WDR C;  1E7P C;  2WDR D;  4YTN C;  5C3J C;  3AE2 C;  5C3J D;  4YTN D;  3P4R C;  3AE2 D;  2WP9 C;  3P4R D;  3AEB C;  2WP9 D;  3AEB D;  4DDI A; 
#chains in the Genus database with same CATH homology
 1KF6 C;  2WQY C;  1KF6 D;  2WQY D;  1YQ3 C;  3AE7 C;  1YQ3 D;  3AE7 D;  3AE6 C;  1QLB C;  3AE5 D;  3VR8 C;  3AE3 C;  3AE6 D;  3VR8 D;  3AE3 D;  2BS2 C;  2WU2 C;  1NEN C;  3AE1 C;  4YSX C;  2WU2 D;  1NEN D;  3AE1 D;  4YSX D;  1L0V C;  1NEK C;  4YT0 C;  1L0V D;  1NEK D;  4YT0 D;  1ZOY C;  2BS4 C;  2ACZ C;  3AEE C;  1ZOY D;  2ACZ D;  3AEE D;  3P4Q C;  4YSY C;  3VRB C;  3AEA C;  3P4Q D;  4YSY D;  3VRB D;  3AEA D;  3ABV C;  2H89 C;  3P4P C;  3ABV D;  2H89 D;  3P4P D;  1ZP0 C;  4YSZ C;  1ZP0 D;  4YSZ D;  5C2T C;  5C2T D;  3AE5 C;  3AE9 C;  3AEC C;  3AE9 D;  3AEC D;  2WS3 C;  4YXD C;  2WS3 D;  4YXD D;  3AE4 C;  3AE4 D;  2WU5 C;  2WU5 D;  3SFE C;  3SFE D;  4KX6 C;  1KFY C;  4KX6 D;  1KFY D;  3AED C;  2FBW C;  3AED D;  2WDV C;  2FBW D;  3P4S C;  2WDV D;  3AEF C;  3AEG C;  3P4S D;  3AEF D;  3AEG D;  3VRA C;  3VRA D;  2B76 C;  2H88 C;  2B76 D;  2H88 D;  4YTP C;  3SFD C;  2BS3 C;  4YTP D;  3SFD D;  3AE8 C;  2WDQ C;  3CIR C;  3AE8 D;  2WDQ D;  3CIR D;  4YTM C;  4YTM D;  1YQ4 C;  3VR9 C;  1YQ4 D;  3VR9 D;  2WDR C;  1E7P C;  2WDR D;  4YTN C;  5C3J C;  3AE2 C;  5C3J D;  4YTN D;  3P4R C;  3AE2 D;  2WP9 C;  3P4R D;  3AEB C;  2WP9 D;  3AEB D; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...