4YSYC

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with n-[(2,4-dichlorophenyl)methyl]-2-(trifluoromethyl)benzamide
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
153
structure length
153
Chain Sequence
EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 55
structure length 153
sequence length 153
chains with identical sequence G
ec nomenclature
pdb deposition date 2015-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01127 Sdh_cyt Succinate dehydrogenase/Fumarate reductase transmembrane subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4ysyC00
4YXDC 2WU2C 3AEAD 2WDRC 3AEGC 2WDVD 3AE2D 3AECD 4YTND 5C3JD 4YSXD 2B76D 3VR9C 3ABVD 3AEBD 5C2TD 1YQ4D 3AE3D 3P4RD 4YXDD 2WP9C 3AEDC 3AE8D 2WDRD 3AEGD 1KFYC 2WS3C 2FBWD 2ACZD 1YQ3C 3AE4D 4YSZD 3P4QC 3VR8C 3AE8C 2H89C 1NEKC 2FBWC 2ACZC 3SFDC 3AE4C 2WP9D 4YSZC 3AEDD 4YT0C 3AE1C 1KFYD 2WS3D 3CIRC 2BS4C 1YQ3D 3AE5D 3VRBC 4YTMC 3P4QD 3VR8D 4YSYC 2H89D 3P4PD 1QLBC 1NEKD 1E7PC 3AEFD 3SFDD 3AE5C 4YT0D 4YTPD 3AE1D 3VRAD 3P4PC 3CIRD 2BS3C 2WDQC 3VRBD 4YTMD 3AEFC 4YSYD 4YTPC 3SFEC 3VRAC 1ZP0C 2BS2C 3AE9C 3AE7D 3AE6C 1KF6C 2H88D 2WDQD 1NENC 2WQYC 1L0VC 3P4SC 3SFED 3AE7C 2WU5D 2H88C 3AEAC 1ZP0D 2WDVC 3AECC 3AE2C 3AE9D 1ZOYD 3AEED 1KF6D 3AE6D 4KX6D 4YTNC 2WU2D 4YSXC 5C3JC 2B76C 2WU5C 3ABVC 3AEBC 1NEND 2WQYD 1L0VD 5C2TC 3P4SD 1YQ4C 3AE3C 1ZOYC 3AEEC 3VR9D 3P4RC 4KX6C
chains in the Genus database with same CATH superfamily
4YXDC 2WU2C 3AEAD 2WDRC 4DHJA 3AEGC 2WDVD 3AE2D 3AECD 2ZFYA 4DDIA 4YTND 5C3JD 4YSXD 2B76D 3VR9C 3ABVD 3AEBD 5C2TD 1YQ4D 3AE3D 3P4RD 4YXDD 2WP9C 3AEDC 3AE8D 2WDRD 3AEGD 4DDGA 1KFYC 2WS3C 4DHIB 2FBWD 2ACZD 1YQ3C 3AE4D 4YSZD 3P4QC 3VR8C 3AE8C 2H89C 1NEKC 2FBWC 2ACZC 3SFDC 3AE4C 2WP9D 4YSZC 3AEDD 4YT0C 3AE1C 1KFYD 2WS3D 3CIRC 2BS4C 1YQ3D 3AE5D 3VRBC 4YTMC 3P4QD 4LDTA 3VR8D 4YSYC 2H89D 3P4PD 1QLBC 1NEKD 1E7PC 1TFFA 3AEFD 3SFDD 3AE5C 4YT0D 4YTPD 3AE1D 3VRAD 3VONA 3P4PC 4I6LA 3CIRD 2BS3C 2WDQC 3VRBD 4YTMD 3AEFC 4YSYD 4YTPC 3SFEC 3VRAC 4FJVA 1ZP0C 2BS2C 3AE9C 3AE7D 3AE6C 1KF6C 2H88D 2WDQD 1NENC 2WQYC 1L0VC 3P4SC 3SFED 3AE7C 2WU5D 2H88C 3AEAC 1ZP0D 2WDVC 3AECC 3AE2C 3AE9D 1ZOYD 3AEED 1KF6D 3AE6D 4KX6D 4YTNC 2WU2D 4YSXC 5C3JC 2B76C 2WU5C 3ABVC 3AEBC 1NEND 2WQYD 1L0VD 5C2TC 3P4SD 4DHZA 1YQ4C 3AE3C 1ZOYC 3AEEC 3VR9D 3P4RC 4KX6C
chains in the Genus database with same CATH topology
4YXDC 2WU2C 3AEAD 2WDRC 3AEGC 2WDVD 3AE2D 3AECD 4YTND 5C3JD 4YSXD 2B76D 3VR9C 3ABVD 3AEBD 5C2TD 1YQ4D 3AE3D 3P4RD 4YXDD 2WP9C 3AEDC 3AE8D 2WDRD 3AEGD 1KFYC 2WS3C 2FBWD 2ACZD 1YQ3C 3AE4D 4YSZD 3P4QC 3VR8C 3AE8C 2H89C 1NEKC 2FBWC 2ACZC 3SFDC 3AE4C 2WP9D 4YSZC 3AEDD 4YT0C 3AE1C 1KFYD 2WS3D 3CIRC 2BS4C 1YQ3D 3AE5D 3VRBC 4YTMC 3P4QD 3VR8D 4YSYC 2H89D 3P4PD 1QLBC 1NEKD 1E7PC 3AEFD 3SFDD 3AE5C 4YT0D 4YTPD 3AE1D 3VRAD 3P4PC 3CIRD 2BS3C 2WDQC 3VRBD 4YTMD 3AEFC 4YSYD 4YTPC 3SFEC 3VRAC 1ZP0C 2BS2C 3AE9C 3AE7D 3AE6C 1KF6C 2H88D 2WDQD 1NENC 2WQYC 1L0VC 3P4SC 3SFED 3AE7C 2WU5D 2H88C 3AEAC 1ZP0D 2WDVC 3AECC 3AE2C 3AE9D 1ZOYD 3AEED 1KF6D 3AE6D 4KX6D 4YTNC 2WU2D 4YSXC 5C3JC 2B76C 2WU5C 3ABVC 3AEBC 1NEND 2WQYD 1L0VD 5C2TC 3P4SD 1YQ4C 3AE3C 1ZOYC 3AEEC 3VR9D 3P4RC 4KX6C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YXD C;  2WU2 C;  3AEA D;  2WDR C;  3AEG C;  2WDV D;  3AE2 D;  3AEC D;  4YTN D;  5C3J D;  4YSX D;  2B76 D;  3VR9 C;  3ABV D;  3AEB D;  5C2T D;  1YQ4 D;  3AE3 D;  3P4R D;  4YXD D;  2WP9 C;  3AED C;  3AE8 D;  2WDR D;  3AEG D;  1KFY C;  2WS3 C;  2FBW D;  2ACZ D;  1YQ3 C;  3AE4 D;  4YSZ D;  3P4Q C;  3VR8 C;  3AE8 C;  2H89 C;  1NEK C;  2FBW C;  2ACZ C;  3SFD C;  3AE4 C;  2WP9 D;  4YSZ C;  3AED D;  4YT0 C;  3AE1 C;  1KFY D;  2WS3 D;  3CIR C;  2BS4 C;  1YQ3 D;  3AE5 D;  3VRB C;  4YTM C;  3P4Q D;  3VR8 D;  4YSY C;  2H89 D;  3P4P D;  1QLB C;  1NEK D;  1E7P C;  3AEF D;  3SFD D;  3AE5 C;  4YT0 D;  4YTP D;  3AE1 D;  3VRA D;  3P4P C;  3CIR D;  2BS3 C;  2WDQ C;  3VRB D;  4YTM D;  3AEF C;  4YSY D;  4YTP C;  3SFE C;  3VRA C;  1ZP0 C;  2BS2 C;  3AE9 C;  3AE7 D;  3AE6 C;  1KF6 C;  2H88 D;  2WDQ D;  1NEN C;  2WQY C;  1L0V C;  3P4S C;  3SFE D;  3AE7 C;  2WU5 D;  2H88 C;  3AEA C;  1ZP0 D;  2WDV C;  3AEC C;  3AE2 C;  3AE9 D;  1ZOY D;  3AEE D;  1KF6 D;  3AE6 D;  4KX6 D;  4YTN C;  2WU2 D;  4YSX C;  5C3J C;  2B76 C;  2WU5 C;  3ABV C;  3AEB C;  1NEN D;  2WQY D;  1L0V D;  5C2T C;  3P4S D;  1YQ4 C;  3AE3 C;  1ZOY C;  3AEE C;  3VR9 D;  3P4R C;  4KX6 C; 
#chains in the Genus database with same CATH topology
 4YXD C;  2WU2 C;  3AEA D;  2WDR C;  4DHJ A;  3AEG C;  2WDV D;  3AE2 D;  3AEC D;  2ZFY A;  4DDI A;  4YTN D;  5C3J D;  4YSX D;  2B76 D;  3VR9 C;  3ABV D;  3AEB D;  5C2T D;  1YQ4 D;  3AE3 D;  3P4R D;  4YXD D;  2WP9 C;  3AED C;  3AE8 D;  2WDR D;  3AEG D;  4DDG A;  1KFY C;  2WS3 C;  4DHI B;  2FBW D;  2ACZ D;  1YQ3 C;  3AE4 D;  4YSZ D;  3P4Q C;  3VR8 C;  3AE8 C;  2H89 C;  1NEK C;  2FBW C;  2ACZ C;  3SFD C;  3AE4 C;  2WP9 D;  4YSZ C;  3AED D;  4YT0 C;  3AE1 C;  1KFY D;  2WS3 D;  3CIR C;  2BS4 C;  1YQ3 D;  3AE5 D;  3VRB C;  4YTM C;  3P4Q D;  4LDT A;  3VR8 D;  4YSY C;  2H89 D;  3P4P D;  1QLB C;  1NEK D;  1E7P C;  1TFF A;  3AEF D;  3SFD D;  3AE5 C;  4YT0 D;  4YTP D;  3AE1 D;  3VRA D;  3VON A;  3P4P C;  4I6L A;  3CIR D;  2BS3 C;  2WDQ C;  3VRB D;  4YTM D;  3AEF C;  4YSY D;  4YTP C;  3SFE C;  3VRA C;  4FJV A;  1ZP0 C;  2BS2 C;  3AE9 C;  3AE7 D;  3AE6 C;  1KF6 C;  2H88 D;  2WDQ D;  1NEN C;  2WQY C;  1L0V C;  3P4S C;  3SFE D;  3AE7 C;  2WU5 D;  2H88 C;  3AEA C;  1ZP0 D;  2WDV C;  3AEC C;  3AE2 C;  3AE9 D;  1ZOY D;  3AEE D;  1KF6 D;  3AE6 D;  4KX6 D;  4YTN C;  2WU2 D;  4YSX C;  5C3J C;  2B76 C;  2WU5 C;  3ABV C;  3AEB C;  1NEN D;  2WQY D;  1L0V D;  5C2T C;  3P4S D;  4DHZ A;  1YQ4 C;  3AE3 C;  1ZOY C;  3AEE C;  3VR9 D;  3P4R C;  4KX6 C; 
#chains in the Genus database with same CATH homology
 4YXD C;  2WU2 C;  3AEA D;  2WDR C;  3AEG C;  2WDV D;  3AE2 D;  3AEC D;  4YTN D;  5C3J D;  4YSX D;  2B76 D;  3VR9 C;  3ABV D;  3AEB D;  5C2T D;  1YQ4 D;  3AE3 D;  3P4R D;  4YXD D;  2WP9 C;  3AED C;  3AE8 D;  2WDR D;  3AEG D;  1KFY C;  2WS3 C;  2FBW D;  2ACZ D;  1YQ3 C;  3AE4 D;  4YSZ D;  3P4Q C;  3VR8 C;  3AE8 C;  2H89 C;  1NEK C;  2FBW C;  2ACZ C;  3SFD C;  3AE4 C;  2WP9 D;  4YSZ C;  3AED D;  4YT0 C;  3AE1 C;  1KFY D;  2WS3 D;  3CIR C;  2BS4 C;  1YQ3 D;  3AE5 D;  3VRB C;  4YTM C;  3P4Q D;  3VR8 D;  4YSY C;  2H89 D;  3P4P D;  1QLB C;  1NEK D;  1E7P C;  3AEF D;  3SFD D;  3AE5 C;  4YT0 D;  4YTP D;  3AE1 D;  3VRA D;  3P4P C;  3CIR D;  2BS3 C;  2WDQ C;  3VRB D;  4YTM D;  3AEF C;  4YSY D;  4YTP C;  3SFE C;  3VRA C;  1ZP0 C;  2BS2 C;  3AE9 C;  3AE7 D;  3AE6 C;  1KF6 C;  2H88 D;  2WDQ D;  1NEN C;  2WQY C;  1L0V C;  3P4S C;  3SFE D;  3AE7 C;  2WU5 D;  2H88 C;  3AEA C;  1ZP0 D;  2WDV C;  3AEC C;  3AE2 C;  3AE9 D;  1ZOY D;  3AEE D;  1KF6 D;  3AE6 D;  4KX6 D;  4YTN C;  2WU2 D;  4YSX C;  5C3J C;  2B76 C;  2WU5 C;  3ABV C;  3AEB C;  1NEN D;  2WQY D;  1L0V D;  5C2T C;  3P4S D;  1YQ4 C;  3AE3 C;  1ZOY C;  3AEE C;  3VR9 D;  3P4R C;  4KX6 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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