3CIRC

E. coli quinol fumarate reductase frda t234a mutation
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
130
structure length
130
Chain Sequence
TTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A threonine on the active site loop controls transition state formation in Escherichia coli respiratory complex II.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Fumarate reductase flavoprotein subunit
total genus 41
structure length 130
sequence length 130
chains with identical sequence O
ec nomenclature
pdb deposition date 2008-03-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF02300 Fumarate_red_C Fumarate reductase subunit C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 3cirC00
3P4SC 5C3JD 3AE6D 3SFED 3VR9C 3VRBD 3AE4D 1NEKC 1ZP0C 3AE7D 1KF6D 1ZOYC 3AECD 3AE9D 1KFYC 3ABVC 3AEDC 3P4QD 4YT0C 1YQ4D 2WQYD 3AE5D 2WDVD 3AE6C 3SFEC 4YXDD 3VRBC 3AE4C 2B76D 3AE7C 1E7PC 1KF6C 3AECC 3AE9C 4KX6C 2H88D 2WU5D 3P4QC 4YSXD 1YQ4C 2WQYC 2FBWD 3CIRD 3AE5C 2BS4C 3VR8D 2WDVC 4YTND 4YXDC 4KX6D 2B76C 3P4PD 3AE8D 2H89D 4YSZD 2H88C 2WU5C 3SFDD 2ACZD 3AE3D 4YTMC 4YSXC 3AEEC 5C2TD 2FBWC 3CIRC 3VR8C 3AEAD 3AEBD 3AE1D 4YTNC 4YTPD 3AEGD 1L0VD 3P4PC 4YTMD 3AE8C 2H89C 3AEED 4YSZC 3VRAC 3SFDC 2ACZC 3AE3C 3AEFD 3P4RD 5C2TC 2WDRD 2WDQD 3AEAC 3AE1C 3AEBC 4YTPC 3VRAD 2WP9D 3AEGC 1L0VC 3AE2D 1NEND 4YT0D 3AEFC 3P4RC 2BS3C 1YQ3D 2WS3D 2WDRC 4YSYD 2WDQC 2WU2D 2BS2C 2WP9C 1QLBC 3P4SD 3AE2C 1NENC 3VR9D 1NEKD 1ZP0D 5C3JC 1ZOYD 1KFYD 1YQ3C 2WS3C 3ABVD 3AEDD 4YSYC 2WU2C
chains in the Genus database with same CATH superfamily
3P4SC 5C3JD 3AE6D 3SFED 3VR9C 3VRBD 3AE4D 1NEKC 1ZP0C 4DDIA 3AE7D 1KF6D 1ZOYC 3AECD 3AE9D 1KFYC 3ABVC 3AEDC 3P4QD 4YT0C 1YQ4D 2ZFYA 2WQYD 4DHIB 3AE5D 2WDVD 3AE6C 3SFEC 4YXDD 3VRBC 3AE4C 2B76D 3AE7C 1E7PC 1KF6C 3AECC 3AE9C 4KX6C 2H88D 2WU5D 3P4QC 4DHJA 4YSXD 1YQ4C 2WQYC 2FBWD 3CIRD 3AE5C 2BS4C 3VR8D 2WDVC 4YTND 4YXDC 4KX6D 2B76C 3P4PD 3AE8D 2H89D 4YSZD 2H88C 2WU5C 3SFDD 2ACZD 3AE3D 4YTMC 4YSXC 3VONA 3AEEC 5C2TD 2FBWC 3CIRC 4LDTA 3VR8C 3AEAD 3AEBD 3AE1D 4YTNC 4YTPD 3AEGD 1L0VD 3P4PC 4YTMD 3AE8C 4DDGA 2H89C 3AEED 4YSZC 3VRAC 3SFDC 2ACZC 3AE3C 3AEFD 3P4RD 5C2TC 2WDRD 2WDQD 3AEAC 3AE1C 3AEBC 4YTPC 3VRAD 2WP9D 3AEGC 1L0VC 3AE2D 1NEND 4YT0D 4DHZA 3AEFC 3P4RC 2BS3C 1YQ3D 2WS3D 2WDRC 4YSYD 2WDQC 2WU2D 2BS2C 2WP9C 1QLBC 4FJVA 3P4SD 3AE2C 4I6LA 1NENC 3VR9D 1TFFA 1NEKD 1ZP0D 5C3JC 1ZOYD 1KFYD 1YQ3C 2WS3C 3ABVD 3AEDD 4YSYC 2WU2C
chains in the Genus database with same CATH topology
3P4SC 5C3JD 3AE6D 3SFED 3VR9C 3VRBD 3AE4D 1NEKC 1ZP0C 3AE7D 1KF6D 1ZOYC 3AECD 3AE9D 1KFYC 3ABVC 3AEDC 3P4QD 4YT0C 1YQ4D 2WQYD 3AE5D 2WDVD 3AE6C 3SFEC 4YXDD 3VRBC 3AE4C 2B76D 3AE7C 1E7PC 1KF6C 3AECC 3AE9C 4KX6C 2H88D 2WU5D 3P4QC 4YSXD 1YQ4C 2WQYC 2FBWD 3CIRD 3AE5C 2BS4C 3VR8D 2WDVC 4YTND 4YXDC 4KX6D 2B76C 3P4PD 3AE8D 2H89D 4YSZD 2H88C 2WU5C 3SFDD 2ACZD 3AE3D 4YTMC 4YSXC 3AEEC 5C2TD 2FBWC 3CIRC 3VR8C 3AEAD 3AEBD 3AE1D 4YTNC 4YTPD 3AEGD 1L0VD 3P4PC 4YTMD 3AE8C 2H89C 3AEED 4YSZC 3VRAC 3SFDC 2ACZC 3AE3C 3AEFD 3P4RD 5C2TC 2WDRD 2WDQD 3AEAC 3AE1C 3AEBC 4YTPC 3VRAD 2WP9D 3AEGC 1L0VC 3AE2D 1NEND 4YT0D 3AEFC 3P4RC 2BS3C 1YQ3D 2WS3D 2WDRC 4YSYD 2WDQC 2WU2D 2BS2C 2WP9C 1QLBC 3P4SD 3AE2C 1NENC 3VR9D 1NEKD 1ZP0D 5C3JC 1ZOYD 1KFYD 1YQ3C 2WS3C 3ABVD 3AEDD 4YSYC 2WU2C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P4S C;  5C3J D;  3AE6 D;  3SFE D;  3VR9 C;  3VRB D;  3AE4 D;  1NEK C;  1ZP0 C;  3AE7 D;  1KF6 D;  1ZOY C;  3AEC D;  3AE9 D;  1KFY C;  3ABV C;  3AED C;  3P4Q D;  4YT0 C;  1YQ4 D;  2WQY D;  3AE5 D;  2WDV D;  3AE6 C;  3SFE C;  4YXD D;  3VRB C;  3AE4 C;  2B76 D;  3AE7 C;  1E7P C;  1KF6 C;  3AEC C;  3AE9 C;  4KX6 C;  2H88 D;  2WU5 D;  3P4Q C;  4YSX D;  1YQ4 C;  2WQY C;  2FBW D;  3CIR D;  3AE5 C;  2BS4 C;  3VR8 D;  2WDV C;  4YTN D;  4YXD C;  4KX6 D;  2B76 C;  3P4P D;  3AE8 D;  2H89 D;  4YSZ D;  2H88 C;  2WU5 C;  3SFD D;  2ACZ D;  3AE3 D;  4YTM C;  4YSX C;  3AEE C;  5C2T D;  2FBW C;  3CIR C;  3VR8 C;  3AEA D;  3AEB D;  3AE1 D;  4YTN C;  4YTP D;  3AEG D;  1L0V D;  3P4P C;  4YTM D;  3AE8 C;  2H89 C;  3AEE D;  4YSZ C;  3VRA C;  3SFD C;  2ACZ C;  3AE3 C;  3AEF D;  3P4R D;  5C2T C;  2WDR D;  2WDQ D;  3AEA C;  3AE1 C;  3AEB C;  4YTP C;  3VRA D;  2WP9 D;  3AEG C;  1L0V C;  3AE2 D;  1NEN D;  4YT0 D;  3AEF C;  3P4R C;  2BS3 C;  1YQ3 D;  2WS3 D;  2WDR C;  4YSY D;  2WDQ C;  2WU2 D;  2BS2 C;  2WP9 C;  1QLB C;  3P4S D;  3AE2 C;  1NEN C;  3VR9 D;  1NEK D;  1ZP0 D;  5C3J C;  1ZOY D;  1KFY D;  1YQ3 C;  2WS3 C;  3ABV D;  3AED D;  4YSY C;  2WU2 C; 
#chains in the Genus database with same CATH topology
 3P4S C;  5C3J D;  3AE6 D;  3SFE D;  3VR9 C;  3VRB D;  3AE4 D;  1NEK C;  1ZP0 C;  4DDI A;  3AE7 D;  1KF6 D;  1ZOY C;  3AEC D;  3AE9 D;  1KFY C;  3ABV C;  3AED C;  3P4Q D;  4YT0 C;  1YQ4 D;  2ZFY A;  2WQY D;  4DHI B;  3AE5 D;  2WDV D;  3AE6 C;  3SFE C;  4YXD D;  3VRB C;  3AE4 C;  2B76 D;  3AE7 C;  1E7P C;  1KF6 C;  3AEC C;  3AE9 C;  4KX6 C;  2H88 D;  2WU5 D;  3P4Q C;  4DHJ A;  4YSX D;  1YQ4 C;  2WQY C;  2FBW D;  3CIR D;  3AE5 C;  2BS4 C;  3VR8 D;  2WDV C;  4YTN D;  4YXD C;  4KX6 D;  2B76 C;  3P4P D;  3AE8 D;  2H89 D;  4YSZ D;  2H88 C;  2WU5 C;  3SFD D;  2ACZ D;  3AE3 D;  4YTM C;  4YSX C;  3VON A;  3AEE C;  5C2T D;  2FBW C;  3CIR C;  4LDT A;  3VR8 C;  3AEA D;  3AEB D;  3AE1 D;  4YTN C;  4YTP D;  3AEG D;  1L0V D;  3P4P C;  4YTM D;  3AE8 C;  4DDG A;  2H89 C;  3AEE D;  4YSZ C;  3VRA C;  3SFD C;  2ACZ C;  3AE3 C;  3AEF D;  3P4R D;  5C2T C;  2WDR D;  2WDQ D;  3AEA C;  3AE1 C;  3AEB C;  4YTP C;  3VRA D;  2WP9 D;  3AEG C;  1L0V C;  3AE2 D;  1NEN D;  4YT0 D;  4DHZ A;  3AEF C;  3P4R C;  2BS3 C;  1YQ3 D;  2WS3 D;  2WDR C;  4YSY D;  2WDQ C;  2WU2 D;  2BS2 C;  2WP9 C;  1QLB C;  4FJV A;  3P4S D;  3AE2 C;  4I6L A;  1NEN C;  3VR9 D;  1TFF A;  1NEK D;  1ZP0 D;  5C3J C;  1ZOY D;  1KFY D;  1YQ3 C;  2WS3 C;  3ABV D;  3AED D;  4YSY C;  2WU2 C; 
#chains in the Genus database with same CATH homology
 3P4S C;  5C3J D;  3AE6 D;  3SFE D;  3VR9 C;  3VRB D;  3AE4 D;  1NEK C;  1ZP0 C;  3AE7 D;  1KF6 D;  1ZOY C;  3AEC D;  3AE9 D;  1KFY C;  3ABV C;  3AED C;  3P4Q D;  4YT0 C;  1YQ4 D;  2WQY D;  3AE5 D;  2WDV D;  3AE6 C;  3SFE C;  4YXD D;  3VRB C;  3AE4 C;  2B76 D;  3AE7 C;  1E7P C;  1KF6 C;  3AEC C;  3AE9 C;  4KX6 C;  2H88 D;  2WU5 D;  3P4Q C;  4YSX D;  1YQ4 C;  2WQY C;  2FBW D;  3CIR D;  3AE5 C;  2BS4 C;  3VR8 D;  2WDV C;  4YTN D;  4YXD C;  4KX6 D;  2B76 C;  3P4P D;  3AE8 D;  2H89 D;  4YSZ D;  2H88 C;  2WU5 C;  3SFD D;  2ACZ D;  3AE3 D;  4YTM C;  4YSX C;  3AEE C;  5C2T D;  2FBW C;  3CIR C;  3VR8 C;  3AEA D;  3AEB D;  3AE1 D;  4YTN C;  4YTP D;  3AEG D;  1L0V D;  3P4P C;  4YTM D;  3AE8 C;  2H89 C;  3AEE D;  4YSZ C;  3VRA C;  3SFD C;  2ACZ C;  3AE3 C;  3AEF D;  3P4R D;  5C2T C;  2WDR D;  2WDQ D;  3AEA C;  3AE1 C;  3AEB C;  4YTP C;  3VRA D;  2WP9 D;  3AEG C;  1L0V C;  3AE2 D;  1NEN D;  4YT0 D;  3AEF C;  3P4R C;  2BS3 C;  1YQ3 D;  2WS3 D;  2WDR C;  4YSY D;  2WDQ C;  2WU2 D;  2BS2 C;  2WP9 C;  1QLB C;  3P4S D;  3AE2 C;  1NEN C;  3VR9 D;  1NEK D;  1ZP0 D;  5C3J C;  1ZOY D;  1KFY D;  1YQ3 C;  2WS3 C;  3ABV D;  3AED D;  4YSY C;  2WU2 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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