3SFED

Crystal structure of porcine mitochondrial respiratory complex ii bound with oxaloacetate and thiabendazole
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
102
structure length
102
Chain Sequence
SSKAASLHWTGERVVSVLLLGLLPAAYLNPCSAMDYSLAAALTLHGHWGIGQVVTDYVRGDALQKAAKAGLLALSAFTFAGLCYFNYHDVGICKAVAMLWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thiabendazole inhibits ubiquinone reduction activity of mitochondrial respiratory complex II via a water molecule mediated binding feature.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Succinate dehydrogenase [ubiquinone] flavoprotein subunit, m
total genus 43
structure length 102
sequence length 102
ec nomenclature
pdb deposition date 2011-06-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 3sfeD00
4YTMD 3AEFC 1YQ3D 1YQ4D 3AECC 3AEGC 2WU2C 3P4SD 3AE1D 3VR8C 2WDVC 4YXDD 3AE5D 3P4PC 3VRAC 3AE8D 3AEDD 2ACZD 4YSYD 2BS3C 2H89D 3VR9C 3P4RD 4KX6C 3SFEC 1NENC 3AEED 1ZP0D 3ABVD 5C2TD 2H88C 2WP9D 3AE9C 3VRBC 1NEKD 3CIRC 3AE2C 1KF6D 3AEAD 2WDQD 3AE3D 4YTND 1E7PC 2WDRC 4YT0D 4YSXC 1L0VD 4YSZC 2WQYD 3AE7D 3SFDC 2WS3C 3AECD 3AEBC 3AEGD 3AE8C 2WU2D 2WU5C 4YTPC 3P4QC 3VR8D 3P4RC 2WDVD 2B76C 3P4PD 3ABVC 1KFYC 3VR9D 4KX6D 3AE6C 3SFED 1NEND 3AE4D 2FBWC 1ZOYD 5C3JD 4YTMC 2H88D 1KF6C 1YQ3C 1YQ4C 2BS2C 3AEAC 3P4SC 3VRBD 3AE1C 3AEFD 4YXDC 3AE5C 3AEDC 2ACZC 4YSYC 2H89C 1QLBC 2WDRD 3AEEC 3VRAD 1ZP0C 4YSXD 5C2TC 4YSZD 2WP9C 3SFDD 2WS3D 3AEBD 2WU5D 4YTPD 1NEKC 3P4QD 2BS4C 2B76D 3AE9D 3AE4C 1KFYD 1ZOYC 2WDQC 3CIRD 5C3JC 3AE3C 4YTNC 3AE2D 3AE6D 4YT0C 1L0VC 2FBWD 2WQYC 3AE7C
chains in the Genus database with same CATH superfamily
4YTMD 3AEFC 1YQ3D 1YQ4D 3AECC 3AEGC 2WU2C 3P4SD 3AE1D 3VR8C 2WDVC 4YXDD 3AE5D 3P4PC 3VRAC 3AE8D 3AEDD 2ACZD 4YSYD 2BS3C 2H89D 1TFFA 3VR9C 3P4RD 4KX6C 3SFEC 1NENC 3AEED 1ZP0D 3ABVD 5C2TD 2H88C 2WP9D 3AE9C 3VRBC 1NEKD 3CIRC 3AE2C 1KF6D 3AEAD 2ZFYA 2WDQD 3AE3D 4YTND 1E7PC 2WDRC 4YT0D 4YSXC 1L0VD 4YSZC 2WQYD 3AE7D 3SFDC 4DHIB 2WS3C 3AECD 3AEBC 3AEGD 3AE8C 2WU2D 2WU5C 4YTPC 3P4QC 4I6LA 3VR8D 3P4RC 2WDVD 2B76C 3P4PD 3ABVC 1KFYC 3VR9D 4KX6D 3AE6C 4LDTA 3SFED 1NEND 3VONA 3AE4D 2FBWC 1ZOYD 5C3JD 4YTMC 2H88D 4DHJA 1KF6C 1YQ3C 1YQ4C 2BS2C 3AEAC 3P4SC 3VRBD 3AE1C 3AEFD 4YXDC 3AE5C 3AEDC 2ACZC 4DHZA 2H89C 4YSYC 1QLBC 2WDRD 3AEEC 3VRAD 4DDIA 1ZP0C 4YSXD 5C2TC 4YSZD 2WP9C 3SFDD 2WS3D 3AEBD 2WU5D 4YTPD 1NEKC 3P4QD 2BS4C 2B76D 3AE9D 3AE4C 1KFYD 4DDGA 1ZOYC 2WDQC 3CIRD 5C3JC 3AE3C 4YTNC 3AE2D 3AE6D 4FJVA 4YT0C 1L0VC 2FBWD 2WQYC 3AE7C
chains in the Genus database with same CATH topology
4YTMD 3AEFC 1YQ3D 1YQ4D 3AECC 3AEGC 2WU2C 3P4SD 3AE1D 3VR8C 2WDVC 4YXDD 3AE5D 3P4PC 3VRAC 3AE8D 3AEDD 2ACZD 4YSYD 2BS3C 2H89D 3VR9C 3P4RD 4KX6C 3SFEC 1NENC 3AEED 1ZP0D 3ABVD 5C2TD 2H88C 2WP9D 3AE9C 3VRBC 1NEKD 3CIRC 3AE2C 1KF6D 3AEAD 2WDQD 3AE3D 4YTND 1E7PC 2WDRC 4YT0D 4YSXC 1L0VD 4YSZC 2WQYD 3AE7D 3SFDC 2WS3C 3AECD 3AEBC 3AEGD 3AE8C 2WU2D 2WU5C 4YTPC 3P4QC 3VR8D 3P4RC 2WDVD 2B76C 3P4PD 3ABVC 1KFYC 3VR9D 4KX6D 3AE6C 3SFED 1NEND 3AE4D 2FBWC 1ZOYD 5C3JD 4YTMC 2H88D 1KF6C 1YQ3C 1YQ4C 2BS2C 3AEAC 3P4SC 3VRBD 3AE1C 3AEFD 4YXDC 3AE5C 3AEDC 2ACZC 4YSYC 2H89C 1QLBC 2WDRD 3AEEC 3VRAD 1ZP0C 4YSXD 5C2TC 4YSZD 2WP9C 3SFDD 2WS3D 3AEBD 2WU5D 4YTPD 1NEKC 3P4QD 2BS4C 2B76D 3AE9D 3AE4C 1KFYD 1ZOYC 2WDQC 3CIRD 5C3JC 3AE3C 4YTNC 3AE2D 3AE6D 4YT0C 1L0VC 2FBWD 2WQYC 3AE7C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YTM D;  3AEF C;  1YQ3 D;  1YQ4 D;  3AEC C;  3AEG C;  2WU2 C;  3P4S D;  3AE1 D;  3VR8 C;  2WDV C;  4YXD D;  3AE5 D;  3P4P C;  3VRA C;  3AE8 D;  3AED D;  2ACZ D;  4YSY D;  2BS3 C;  2H89 D;  3VR9 C;  3P4R D;  4KX6 C;  3SFE C;  1NEN C;  3AEE D;  1ZP0 D;  3ABV D;  5C2T D;  2H88 C;  2WP9 D;  3AE9 C;  3VRB C;  1NEK D;  3CIR C;  3AE2 C;  1KF6 D;  3AEA D;  2WDQ D;  3AE3 D;  4YTN D;  1E7P C;  2WDR C;  4YT0 D;  4YSX C;  1L0V D;  4YSZ C;  2WQY D;  3AE7 D;  3SFD C;  2WS3 C;  3AEC D;  3AEB C;  3AEG D;  3AE8 C;  2WU2 D;  2WU5 C;  4YTP C;  3P4Q C;  3VR8 D;  3P4R C;  2WDV D;  2B76 C;  3P4P D;  3ABV C;  1KFY C;  3VR9 D;  4KX6 D;  3AE6 C;  3SFE D;  1NEN D;  3AE4 D;  2FBW C;  1ZOY D;  5C3J D;  4YTM C;  2H88 D;  1KF6 C;  1YQ3 C;  1YQ4 C;  2BS2 C;  3AEA C;  3P4S C;  3VRB D;  3AE1 C;  3AEF D;  4YXD C;  3AE5 C;  3AED C;  2ACZ C;  4YSY C;  2H89 C;  1QLB C;  2WDR D;  3AEE C;  3VRA D;  1ZP0 C;  4YSX D;  5C2T C;  4YSZ D;  2WP9 C;  3SFD D;  2WS3 D;  3AEB D;  2WU5 D;  4YTP D;  1NEK C;  3P4Q D;  2BS4 C;  2B76 D;  3AE9 D;  3AE4 C;  1KFY D;  1ZOY C;  2WDQ C;  3CIR D;  5C3J C;  3AE3 C;  4YTN C;  3AE2 D;  3AE6 D;  4YT0 C;  1L0V C;  2FBW D;  2WQY C;  3AE7 C; 
#chains in the Genus database with same CATH topology
 4YTM D;  3AEF C;  1YQ3 D;  1YQ4 D;  3AEC C;  3AEG C;  2WU2 C;  3P4S D;  3AE1 D;  3VR8 C;  2WDV C;  4YXD D;  3AE5 D;  3P4P C;  3VRA C;  3AE8 D;  3AED D;  2ACZ D;  4YSY D;  2BS3 C;  2H89 D;  1TFF A;  3VR9 C;  3P4R D;  4KX6 C;  3SFE C;  1NEN C;  3AEE D;  1ZP0 D;  3ABV D;  5C2T D;  2H88 C;  2WP9 D;  3AE9 C;  3VRB C;  1NEK D;  3CIR C;  3AE2 C;  1KF6 D;  3AEA D;  2ZFY A;  2WDQ D;  3AE3 D;  4YTN D;  1E7P C;  2WDR C;  4YT0 D;  4YSX C;  1L0V D;  4YSZ C;  2WQY D;  3AE7 D;  3SFD C;  4DHI B;  2WS3 C;  3AEC D;  3AEB C;  3AEG D;  3AE8 C;  2WU2 D;  2WU5 C;  4YTP C;  3P4Q C;  4I6L A;  3VR8 D;  3P4R C;  2WDV D;  2B76 C;  3P4P D;  3ABV C;  1KFY C;  3VR9 D;  4KX6 D;  3AE6 C;  4LDT A;  3SFE D;  1NEN D;  3VON A;  3AE4 D;  2FBW C;  1ZOY D;  5C3J D;  4YTM C;  2H88 D;  4DHJ A;  1KF6 C;  1YQ3 C;  1YQ4 C;  2BS2 C;  3AEA C;  3P4S C;  3VRB D;  3AE1 C;  3AEF D;  4YXD C;  3AE5 C;  3AED C;  2ACZ C;  4DHZ A;  2H89 C;  4YSY C;  1QLB C;  2WDR D;  3AEE C;  3VRA D;  4DDI A;  1ZP0 C;  4YSX D;  5C2T C;  4YSZ D;  2WP9 C;  3SFD D;  2WS3 D;  3AEB D;  2WU5 D;  4YTP D;  1NEK C;  3P4Q D;  2BS4 C;  2B76 D;  3AE9 D;  3AE4 C;  1KFY D;  4DDG A;  1ZOY C;  2WDQ C;  3CIR D;  5C3J C;  3AE3 C;  4YTN C;  3AE2 D;  3AE6 D;  4FJV A;  4YT0 C;  1L0V C;  2FBW D;  2WQY C;  3AE7 C; 
#chains in the Genus database with same CATH homology
 4YTM D;  3AEF C;  1YQ3 D;  1YQ4 D;  3AEC C;  3AEG C;  2WU2 C;  3P4S D;  3AE1 D;  3VR8 C;  2WDV C;  4YXD D;  3AE5 D;  3P4P C;  3VRA C;  3AE8 D;  3AED D;  2ACZ D;  4YSY D;  2BS3 C;  2H89 D;  3VR9 C;  3P4R D;  4KX6 C;  3SFE C;  1NEN C;  3AEE D;  1ZP0 D;  3ABV D;  5C2T D;  2H88 C;  2WP9 D;  3AE9 C;  3VRB C;  1NEK D;  3CIR C;  3AE2 C;  1KF6 D;  3AEA D;  2WDQ D;  3AE3 D;  4YTN D;  1E7P C;  2WDR C;  4YT0 D;  4YSX C;  1L0V D;  4YSZ C;  2WQY D;  3AE7 D;  3SFD C;  2WS3 C;  3AEC D;  3AEB C;  3AEG D;  3AE8 C;  2WU2 D;  2WU5 C;  4YTP C;  3P4Q C;  3VR8 D;  3P4R C;  2WDV D;  2B76 C;  3P4P D;  3ABV C;  1KFY C;  3VR9 D;  4KX6 D;  3AE6 C;  3SFE D;  1NEN D;  3AE4 D;  2FBW C;  1ZOY D;  5C3J D;  4YTM C;  2H88 D;  1KF6 C;  1YQ3 C;  1YQ4 C;  2BS2 C;  3AEA C;  3P4S C;  3VRB D;  3AE1 C;  3AEF D;  4YXD C;  3AE5 C;  3AED C;  2ACZ C;  4YSY C;  2H89 C;  1QLB C;  2WDR D;  3AEE C;  3VRA D;  1ZP0 C;  4YSX D;  5C2T C;  4YSZ D;  2WP9 C;  3SFD D;  2WS3 D;  3AEB D;  2WU5 D;  4YTP D;  1NEK C;  3P4Q D;  2BS4 C;  2B76 D;  3AE9 D;  3AE4 C;  1KFY D;  1ZOY C;  2WDQ C;  3CIR D;  5C3J C;  3AE3 C;  4YTN C;  3AE2 D;  3AE6 D;  4YT0 C;  1L0V C;  2FBW D;  2WQY C;  3AE7 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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