3VRAC

Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode ascaris suum with the specific inhibitor atpenin a5
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
153
structure length
153
Chain Sequence
EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/oxidoreductase inhibitor
publication title Crystal structure of mitochondrial quinol-fumarate reductase from parasitic nematode Ascaris suum
rcsb
molecule keywords Flavoprotein subunit of complex II
total genus 48
structure length 153
sequence length 153
chains with identical sequence G
ec nomenclature
pdb deposition date 2012-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01127 Sdh_cyt Succinate dehydrogenase/Fumarate reductase transmembrane subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 3vraC00
2WS3C 1ZP0C 3AEBD 3CIRD 2BS4C 2WU2D 1QLBC 4YTMD 1YQ3C 3VRBC 2ACZD 2WDRD 2WP9C 3SFDC 1ZP0D 3SFEC 3P4PC 3VR9C 5C2TC 3AEFC 1YQ3D 3VRBD 2WP9D 3SFDD 3AE2C 1ZOYC 2H88C 3AEDC 3AE4C 3SFED 3P4PD 4YXDC 3AE8C 3VR9D 5C2TD 3AEFD 3AEGC 1NEKC 5C3JC 3AE2D 1ZOYD 3AE7C 3AE9C 4YSXC 2H88D 3AEDD 2WU5C 3AECC 3AE4D 4YXDD 2BS3C 3AE8D 2WDVC 2WQYC 3AEGD 2WS3D 1NEKD 5C3JD 3AE7D 3AEAC 3AE9D 4YSXD 3VRAC 3P4SC 4KX6C 2WU5D 3AECD 2WDVD 2WQYD 1L0VC 4YSZC 1KFYC 3AE6C 2FBWC 3VRAD 3P4SD 4KX6D 2WDQC 2H89C 1L0VD 4YSZD 1KFYD 3AE6D 2FBWD 2WDQD 2H89D 4YT0C 3AE1C 3AE5C 4YSYC 3AEEC 3AE3C 4YT0D 3VR8C 3ABVC 3AEAD 1YQ4C 3AE1D 3AE5D 4YTPC 1NENC 1E7PC 2B76C 4YSYD 3P4QC 1KF6C 3AEED 3AE3D 3P4RC 3VR8D 3ABVD 4YTNC 1YQ4D 3AEBC 1NEND 2B76D 3CIRC 4YTPD 2WU2C 3P4QD 1KF6D 2BS2C 3P4RD 4YTMC 2ACZC 2WDRC 4YTND
chains in the Genus database with same CATH superfamily
2WS3C 1ZP0C 3AEBD 3CIRD 2BS4C 2WU2D 4DHZA 1QLBC 4YTMD 1YQ3C 3VRBC 2ACZD 2WDRD 2WP9C 3SFDC 1ZP0D 3SFEC 3P4PC 3VR9C 5C2TC 3AEFC 1YQ3D 3VRBD 2WP9D 3SFDD 3AE2C 1ZOYC 2H88C 3AEDC 3AE4C 3SFED 3P4PD 4YXDC 4FJVA 3AE8C 3VR9D 5C2TD 3AEFD 3AEGC 1NEKC 5C3JC 3AE2D 1ZOYD 3AE7C 3AE9C 4YSXC 2H88D 3AEDD 4DHIB 2WU5C 3AECC 3AE4D 4YXDD 2BS3C 3AE8D 2WDVC 2WQYC 4LDTA 3AEGD 2WS3D 1NEKD 5C3JD 3AE7D 3AEAC 3AE9D 4YSXD 3VRAC 3P4SC 4KX6C 2WU5D 3AECD 2WDVD 4I6LA 2WQYD 1L0VC 4YSZC 4DDIA 1KFYC 3AE6C 2FBWC 3VRAD 3P4SD 4KX6D 2WDQC 2H89C 2ZFYA 1L0VD 4YSZD 1KFYD 3AE6D 2FBWD 1TFFA 2WDQD 2H89D 4YT0C 3AE1C 3AE5C 4YSYC 3AEEC 3AE3C 4YT0D 3VR8C 3ABVC 3AEAD 1YQ4C 3AE1D 3AE5D 4YTPC 1NENC 1E7PC 2B76C 4YSYD 3P4QC 1KF6C 3AEED 3AE3D 3VONA 4DHJA 3P4RC 3VR8D 3ABVD 4YTNC 1YQ4D 3AEBC 1NEND 2B76D 3CIRC 4YTPD 2WU2C 3P4QD 1KF6D 2BS2C 3P4RD 4YTMC 2ACZC 2WDRC 4YTND 4DDGA
chains in the Genus database with same CATH topology
2WS3C 1ZP0C 3AEBD 3CIRD 2BS4C 2WU2D 1QLBC 4YTMD 1YQ3C 3VRBC 2ACZD 2WDRD 2WP9C 3SFDC 1ZP0D 3SFEC 3P4PC 3VR9C 5C2TC 3AEFC 1YQ3D 3VRBD 2WP9D 3SFDD 3AE2C 1ZOYC 2H88C 3AEDC 3AE4C 3SFED 3P4PD 4YXDC 3AE8C 3VR9D 5C2TD 3AEFD 3AEGC 1NEKC 5C3JC 3AE2D 1ZOYD 3AE7C 3AE9C 4YSXC 2H88D 3AEDD 2WU5C 3AECC 3AE4D 4YXDD 2BS3C 3AE8D 2WDVC 2WQYC 3AEGD 2WS3D 1NEKD 5C3JD 3AE7D 3AEAC 3AE9D 4YSXD 3VRAC 3P4SC 4KX6C 2WU5D 3AECD 2WDVD 2WQYD 1L0VC 4YSZC 1KFYC 3AE6C 2FBWC 3VRAD 3P4SD 4KX6D 2WDQC 2H89C 1L0VD 4YSZD 1KFYD 3AE6D 2FBWD 2WDQD 2H89D 4YT0C 3AE1C 3AE5C 4YSYC 3AEEC 3AE3C 4YT0D 3VR8C 3ABVC 3AEAD 1YQ4C 3AE1D 3AE5D 4YTPC 1NENC 1E7PC 2B76C 4YSYD 3P4QC 1KF6C 3AEED 3AE3D 3P4RC 3VR8D 3ABVD 4YTNC 1YQ4D 3AEBC 1NEND 2B76D 3CIRC 4YTPD 2WU2C 3P4QD 1KF6D 2BS2C 3P4RD 4YTMC 2ACZC 2WDRC 4YTND
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WS3 C;  1ZP0 C;  3AEB D;  3CIR D;  2BS4 C;  2WU2 D;  1QLB C;  4YTM D;  1YQ3 C;  3VRB C;  2ACZ D;  2WDR D;  2WP9 C;  3SFD C;  1ZP0 D;  3SFE C;  3P4P C;  3VR9 C;  5C2T C;  3AEF C;  1YQ3 D;  3VRB D;  2WP9 D;  3SFD D;  3AE2 C;  1ZOY C;  2H88 C;  3AED C;  3AE4 C;  3SFE D;  3P4P D;  4YXD C;  3AE8 C;  3VR9 D;  5C2T D;  3AEF D;  3AEG C;  1NEK C;  5C3J C;  3AE2 D;  1ZOY D;  3AE7 C;  3AE9 C;  4YSX C;  2H88 D;  3AED D;  2WU5 C;  3AEC C;  3AE4 D;  4YXD D;  2BS3 C;  3AE8 D;  2WDV C;  2WQY C;  3AEG D;  2WS3 D;  1NEK D;  5C3J D;  3AE7 D;  3AEA C;  3AE9 D;  4YSX D;  3VRA C;  3P4S C;  4KX6 C;  2WU5 D;  3AEC D;  2WDV D;  2WQY D;  1L0V C;  4YSZ C;  1KFY C;  3AE6 C;  2FBW C;  3VRA D;  3P4S D;  4KX6 D;  2WDQ C;  2H89 C;  1L0V D;  4YSZ D;  1KFY D;  3AE6 D;  2FBW D;  2WDQ D;  2H89 D;  4YT0 C;  3AE1 C;  3AE5 C;  4YSY C;  3AEE C;  3AE3 C;  4YT0 D;  3VR8 C;  3ABV C;  3AEA D;  1YQ4 C;  3AE1 D;  3AE5 D;  4YTP C;  1NEN C;  1E7P C;  2B76 C;  4YSY D;  3P4Q C;  1KF6 C;  3AEE D;  3AE3 D;  3P4R C;  3VR8 D;  3ABV D;  4YTN C;  1YQ4 D;  3AEB C;  1NEN D;  2B76 D;  3CIR C;  4YTP D;  2WU2 C;  3P4Q D;  1KF6 D;  2BS2 C;  3P4R D;  4YTM C;  2ACZ C;  2WDR C;  4YTN D; 
#chains in the Genus database with same CATH topology
 2WS3 C;  1ZP0 C;  3AEB D;  3CIR D;  2BS4 C;  2WU2 D;  4DHZ A;  1QLB C;  4YTM D;  1YQ3 C;  3VRB C;  2ACZ D;  2WDR D;  2WP9 C;  3SFD C;  1ZP0 D;  3SFE C;  3P4P C;  3VR9 C;  5C2T C;  3AEF C;  1YQ3 D;  3VRB D;  2WP9 D;  3SFD D;  3AE2 C;  1ZOY C;  2H88 C;  3AED C;  3AE4 C;  3SFE D;  3P4P D;  4YXD C;  4FJV A;  3AE8 C;  3VR9 D;  5C2T D;  3AEF D;  3AEG C;  1NEK C;  5C3J C;  3AE2 D;  1ZOY D;  3AE7 C;  3AE9 C;  4YSX C;  2H88 D;  3AED D;  4DHI B;  2WU5 C;  3AEC C;  3AE4 D;  4YXD D;  2BS3 C;  3AE8 D;  2WDV C;  2WQY C;  4LDT A;  3AEG D;  2WS3 D;  1NEK D;  5C3J D;  3AE7 D;  3AEA C;  3AE9 D;  4YSX D;  3VRA C;  3P4S C;  4KX6 C;  2WU5 D;  3AEC D;  2WDV D;  4I6L A;  2WQY D;  1L0V C;  4YSZ C;  4DDI A;  1KFY C;  3AE6 C;  2FBW C;  3VRA D;  3P4S D;  4KX6 D;  2WDQ C;  2H89 C;  2ZFY A;  1L0V D;  4YSZ D;  1KFY D;  3AE6 D;  2FBW D;  1TFF A;  2WDQ D;  2H89 D;  4YT0 C;  3AE1 C;  3AE5 C;  4YSY C;  3AEE C;  3AE3 C;  4YT0 D;  3VR8 C;  3ABV C;  3AEA D;  1YQ4 C;  3AE1 D;  3AE5 D;  4YTP C;  1NEN C;  1E7P C;  2B76 C;  4YSY D;  3P4Q C;  1KF6 C;  3AEE D;  3AE3 D;  3VON A;  4DHJ A;  3P4R C;  3VR8 D;  3ABV D;  4YTN C;  1YQ4 D;  3AEB C;  1NEN D;  2B76 D;  3CIR C;  4YTP D;  2WU2 C;  3P4Q D;  1KF6 D;  2BS2 C;  3P4R D;  4YTM C;  2ACZ C;  2WDR C;  4YTN D;  4DDG A; 
#chains in the Genus database with same CATH homology
 2WS3 C;  1ZP0 C;  3AEB D;  3CIR D;  2BS4 C;  2WU2 D;  1QLB C;  4YTM D;  1YQ3 C;  3VRB C;  2ACZ D;  2WDR D;  2WP9 C;  3SFD C;  1ZP0 D;  3SFE C;  3P4P C;  3VR9 C;  5C2T C;  3AEF C;  1YQ3 D;  3VRB D;  2WP9 D;  3SFD D;  3AE2 C;  1ZOY C;  2H88 C;  3AED C;  3AE4 C;  3SFE D;  3P4P D;  4YXD C;  3AE8 C;  3VR9 D;  5C2T D;  3AEF D;  3AEG C;  1NEK C;  5C3J C;  3AE2 D;  1ZOY D;  3AE7 C;  3AE9 C;  4YSX C;  2H88 D;  3AED D;  2WU5 C;  3AEC C;  3AE4 D;  4YXD D;  2BS3 C;  3AE8 D;  2WDV C;  2WQY C;  3AEG D;  2WS3 D;  1NEK D;  5C3J D;  3AE7 D;  3AEA C;  3AE9 D;  4YSX D;  3VRA C;  3P4S C;  4KX6 C;  2WU5 D;  3AEC D;  2WDV D;  2WQY D;  1L0V C;  4YSZ C;  1KFY C;  3AE6 C;  2FBW C;  3VRA D;  3P4S D;  4KX6 D;  2WDQ C;  2H89 C;  1L0V D;  4YSZ D;  1KFY D;  3AE6 D;  2FBW D;  2WDQ D;  2H89 D;  4YT0 C;  3AE1 C;  3AE5 C;  4YSY C;  3AEE C;  3AE3 C;  4YT0 D;  3VR8 C;  3ABV C;  3AEA D;  1YQ4 C;  3AE1 D;  3AE5 D;  4YTP C;  1NEN C;  1E7P C;  2B76 C;  4YSY D;  3P4Q C;  1KF6 C;  3AEE D;  3AE3 D;  3P4R C;  3VR8 D;  3ABV D;  4YTN C;  1YQ4 D;  3AEB C;  1NEN D;  2B76 D;  3CIR C;  4YTP D;  2WU2 C;  3P4Q D;  1KF6 D;  2BS2 C;  3P4R D;  4YTM C;  2ACZ C;  2WDR C;  4YTN D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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