4LS9A

Structure of mycobacterial nrna homolog reveals multifunctional nuclease activities
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
319
structure length
319
Chain Sequence
GARVDARGAADLLTAASSVSVICHVYPDADTIGAGLALAQVLAASGKHVEVSFATPAQLPESLQSLPGGHLLVAPEAMRRDADLVVTVDIPSINRLGALSGLAGPGREVLVIDHHASNQLFGTANYIDPSADSTTMLVAELLDAWGKPIDEKVAHCLYAGLTTDTGSFRWATARAHRLAARLVELGVDNASISRTLLDTHPFAWLPMLSRVLATARLLPDALDGRGFVYAVVPHDEWSEARPEEVESIVDIVRTTQQAEVAAVFKEIEPMHWSVSMRAKSVNLASVASAFGGGGHPHAAGYSATGSADDVVQALARALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Mycobacterium smegmatis
publication title Unique subunit packing in mycobacterial nanoRNase leads to alternate substrate recognitions in DHH phosphodiesterases
pubmed doi rcsb
molecule keywords DHH family protein
total genus 105
structure length 319
sequence length 319
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01368 DHH DHH family
A PF02272 DHHA1 DHHA1 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.310.30 Alpha Beta Roll Diaminopimelate Epimerase; Chain A, domain 1 Diaminopimelate Epimerase; Chain A, domain 1 4ls9A02
3.90.1640.10 Alpha Beta Alpha-Beta Complex inorganic pyrophosphatase (n-terminal core) inorganic pyrophosphatase (n-terminal core) 4ls9A01
3W5WA 2ZXRA 2QB7A 1WPNA 1WPMA 4LS9A 2ENXA 1WPPA 2ZXPA 4PY9A 1IR6A 2HAWA 1K20A 2QB8A 2QB6A 1K23A 4RPAA 2ZXOA 3DEVA 2EB0A 2IW4A 1I74A
chains in the Genus database with same CATH superfamily
3G7KA 5GL4A 2ZVFA 5GKXA 1XUAA 4JCIA 1QYAA 1QY9A 4Q60A 3FVEA 4LB0A 4PY9A 2MPBA 2EB0A 3PW9A 2Q9JA 1W61A 1GQZA 5M47A 1W62A 3PTJA 4OA3A 3W5WA 4JUUA 5H2YA 4DUNA 4GL6A 1WPMA 5H2GA 2ZXPA 5GL3A 2PW0A 1T6KA 4JD7A 1YM5A 1K23A 2QB6A 2H9FA 5GL2A 3DEVA 1XUBA 2YMAA 1S7JA 4J9WA 1U1WA 1U1VA 2AZPA 2KW7A 1TM0A 3WQZA 4JBDA 1WPNA 4IK0A 4LS9A 2ENXA 1WPPA 3EKMA 4K7GB 2OTNA 1IR6A 2HAWA 1K20A 2QB8A 2ZXOA 3EJXA 5ANPA 4K8LA 4LG3A 4DWZA 2IW4A 3PVHA 1I74A 2GKJA 2PVZA 4J9XA 1BWZA 4K7XA 2Q9HA 2ZXRA 2QB7A 1SDJA 1U0KA 3G98A 3ICJA 4Q2HA 2GKEA 5HA4A 1U1XA 4FC5A 3EDNA 2LT2A 4RPAA 3IGHX 5IWEA 2KPTA 4IJZA
chains in the Genus database with same CATH topology
3G7KA 5GL4A 2ZVFA 5GKXA 1XUAA 4JCIA 1QYAA 1QY9A 4Q60A 3FVEA 4LB0A 4PY9A 2MPBA 2EB0A 3PW9A 2Q9JA 1W61A 1GQZA 5M47A 1W62A 3PTJA 4OA3A 3W5WA 4JUUA 5H2YA 4DUNA 4GL6A 1WPMA 5H2GA 2ZXPA 5GL3A 2PW0A 1T6KA 4JD7A 1YM5A 1K23A 2QB6A 2H9FA 5GL2A 3DEVA 1XUBA 2YMAA 1S7JA 4J9WA 1U1WA 1U1VA 2AZPA 2KW7A 1TM0A 3WQZA 4JBDA 1WPNA 4IK0A 4LS9A 2ENXA 1WPPA 3EKMA 4K7GB 2OTNA 1IR6A 2HAWA 1K20A 2QB8A 2ZXOA 3EJXA 5ANPA 4K8LA 4LG3A 4DWZA 2IW4A 3PVHA 1I74A 2GKJA 2PVZA 4J9XA 1BWZA 4K7XA 2Q9HA 2ZXRA 2QB7A 1SDJA 1U0KA 3G98A 3ICJA 4Q2HA 2GKEA 5HA4A 1U1XA 4FC5A 3EDNA 2LT2A 4RPAA 3IGHX 5IWEA 2KPTA 4IJZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3W5W A;  2ZXR A;  2QB7 A;  1WPN A;  1WPM A;  4LS9 A;  2ENX A;  1WPP A;  2ZXP A;  4PY9 A;  1IR6 A;  2HAW A;  1K20 A;  2QB8 A;  2QB6 A;  1K23 A;  4RPA A;  2ZXO A;  3DEV A;  2EB0 A;  2IW4 A;  1I74 A; 
#chains in the Genus database with same CATH topology
 3G7K A;  5GL4 A;  2ZVF A;  5GKX A;  1XUA A;  4JCI A;  1QYA A;  1QY9 A;  4Q60 A;  3FVE A;  4LB0 A;  4PY9 A;  2MPB A;  2EB0 A;  3PW9 A;  2Q9J A;  1W61 A;  1GQZ A;  5M47 A;  1W62 A;  3PTJ A;  4OA3 A;  3W5W A;  4JUU A;  5H2Y A;  4DUN A;  4GL6 A;  1WPM A;  5H2G A;  2ZXP A;  5GL3 A;  2PW0 A;  1T6K A;  4JD7 A;  1YM5 A;  1K23 A;  2QB6 A;  2H9F A;  5GL2 A;  3DEV A;  1XUB A;  2YMA A;  1S7J A;  4J9W A;  1U1W A;  1U1V A;  2AZP A;  2KW7 A;  1TM0 A;  3WQZ A;  4JBD A;  1WPN A;  4IK0 A;  4LS9 A;  2ENX A;  1WPP A;  3EKM A;  4K7G B;  2OTN A;  1IR6 A;  2HAW A;  1K20 A;  2QB8 A;  2ZXO A;  3EJX A;  5ANP A;  4K8L A;  4LG3 A;  4DWZ A;  2IW4 A;  3PVH A;  1I74 A;  2GKJ A;  2PVZ A;  4J9X A;  1BWZ A;  4K7X A;  2Q9H A;  2ZXR A;  2QB7 A;  1SDJ A;  1U0K A;  3G98 A;  3ICJ A;  4Q2H A;  2GKE A;  5HA4 A;  1U1X A;  4FC5 A;  3EDN A;  2LT2 A;  4RPA A;  3IGH X;  5IWE A;  2KPT A;  4IJZ A; 
#chains in the Genus database with same CATH homology
 3G7K A;  5GL4 A;  2ZVF A;  5GKX A;  1XUA A;  4JCI A;  1QYA A;  1QY9 A;  4Q60 A;  3FVE A;  4LB0 A;  4PY9 A;  2MPB A;  2EB0 A;  3PW9 A;  2Q9J A;  1W61 A;  1GQZ A;  5M47 A;  1W62 A;  3PTJ A;  4OA3 A;  3W5W A;  4JUU A;  5H2Y A;  4DUN A;  4GL6 A;  1WPM A;  5H2G A;  2ZXP A;  5GL3 A;  2PW0 A;  1T6K A;  4JD7 A;  1YM5 A;  1K23 A;  2QB6 A;  2H9F A;  5GL2 A;  3DEV A;  1XUB A;  2YMA A;  1S7J A;  4J9W A;  1U1W A;  1U1V A;  2AZP A;  2KW7 A;  1TM0 A;  3WQZ A;  4JBD A;  1WPN A;  4IK0 A;  4LS9 A;  2ENX A;  1WPP A;  3EKM A;  4K7G B;  2OTN A;  1IR6 A;  2HAW A;  1K20 A;  2QB8 A;  2ZXO A;  3EJX A;  5ANP A;  4K8L A;  4LG3 A;  4DWZ A;  2IW4 A;  3PVH A;  1I74 A;  2GKJ A;  2PVZ A;  4J9X A;  1BWZ A;  4K7X A;  2Q9H A;  2ZXR A;  2QB7 A;  1SDJ A;  1U0K A;  3G98 A;  3ICJ A;  4Q2H A;  2GKE A;  5HA4 A;  1U1X A;  4FC5 A;  3EDN A;  2LT2 A;  4RPA A;  3IGH X;  5IWE A;  2KPT A;  4IJZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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