4LS9A

Structure of mycobacterial nrna homolog reveals multifunctional nuclease activities
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
319
structure length
319
Chain Sequence
GARVDARGAADLLTAASSVSVICHVYPDADTIGAGLALAQVLAASGKHVEVSFATPAQLPESLQSLPGGHLLVAPEAMRRDADLVVTVDIPSINRLGALSGLAGPGREVLVIDHHASNQLFGTANYIDPSADSTTMLVAELLDAWGKPIDEKVAHCLYAGLTTDTGSFRWATARAHRLAARLVELGVDNASISRTLLDTHPFAWLPMLSRVLATARLLPDALDGRGFVYAVVPHDEWSEARPEEVESIVDIVRTTQQAEVAAVFKEIEPMHWSVSMRAKSVNLASVASAFGGGGHPHAAGYSATGSADDVVQALARALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Unique subunit packing in mycobacterial nanoRNase leads to alternate substrate recognitions in DHH phosphodiesterases
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium smegmatis
molecule keywords DHH family protein
total genus 105
structure length 319
sequence length 319
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01368 DHH DHH family
A PF02272 DHHA1 DHHA1 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.310.30 Alpha Beta Roll Diaminopimelate Epimerase; Chain A, domain 1 Diaminopimelate Epimerase; Chain A, domain 1 4ls9A02
3.90.1640.10 Alpha Beta Alpha-Beta Complex inorganic pyrophosphatase (n-terminal core) inorganic pyrophosphatase (n-terminal core) 4ls9A01
2QB8A 3W5WA 4LS9A 2IW4A 3DEVA 2HAWA 1WPNA 4PY9A 2QB6A 2ZXPA 1K20A 1K23A 2QB7A 4RPAA 1IR6A 2ZXRA 2ZXOA 1WPMA 1WPPA 2EB0A 2ENXA 1I74A
chains in the Genus database with same CATH superfamily
1U1VA 1SDJA 1U0KA 4IK0A 2AZPA 2YMAA 3PVHA 5GL3A 1XUAA 2HAWA 3EKMA 4PY9A 2ZXPA 1YM5A 4OA3A 2Q9JA 1K20A 4RPAA 1IR6A 1I74A 2QB8A 2GKEA 3W5WA 4K7XA 4JBDA 2OTNA 5GKXA 3FVEA 4JUUA 4K8LA 4LS9A 1T6KA 3WQZA 1XUBA 2ZVFA 2QB7A 4DUNA 1WPPA 4JD7A 2KPTA 2Q9HA 4FC5A 4Q60A 2IW4A 3DEVA 4K7GB 1WPNA 4J9WA 5GL4A 5M47A 1TM0A 5GL2A 2LT2A 4GL6A 1U1XA 5HA4A 1BWZA 1W61A 5H2YA 2PVZA 1S7JA 2ZXRA 1WPMA 2EB0A 2H9FA 3ICJA 1W62A 4JCIA 4IJZA 3PTJA 4Q2HA 3EDNA 4LB0A 4J9XA 5IWEA 1QYAA 3EJXA 3PW9A 1U1WA 1GQZA 3G98A 2QB6A 2GKJA 2MPBA 2PW0A 4DWZA 3IGHX 5ANPA 5H2GA 1K23A 3G7KA 4LG3A 2ZXOA 1QY9A 2ENXA 2KW7A
chains in the Genus database with same CATH topology
1U1VA 1SDJA 1U0KA 4IK0A 2AZPA 2YMAA 3PVHA 5GL3A 1XUAA 2HAWA 3EKMA 4PY9A 2ZXPA 1YM5A 4OA3A 2Q9JA 1K20A 4RPAA 1IR6A 1I74A 2QB8A 2GKEA 3W5WA 4K7XA 4JBDA 2OTNA 5GKXA 3FVEA 4JUUA 4K8LA 4LS9A 1T6KA 3WQZA 1XUBA 2ZVFA 2QB7A 4DUNA 1WPPA 4JD7A 2KPTA 2Q9HA 4FC5A 4Q60A 2IW4A 3DEVA 4K7GB 1WPNA 4J9WA 5GL4A 5M47A 1TM0A 5GL2A 2LT2A 4GL6A 1U1XA 5HA4A 1BWZA 1W61A 5H2YA 2PVZA 1S7JA 2ZXRA 1WPMA 2EB0A 2H9FA 3ICJA 1W62A 4JCIA 4IJZA 3PTJA 4Q2HA 3EDNA 4LB0A 4J9XA 5IWEA 1QYAA 3EJXA 3PW9A 1U1WA 1GQZA 3G98A 2QB6A 2GKJA 2MPBA 2PW0A 4DWZA 3IGHX 5ANPA 5H2GA 1K23A 3G7KA 4LG3A 2ZXOA 1QY9A 2ENXA 2KW7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QB8 A;  3W5W A;  4LS9 A;  2IW4 A;  3DEV A;  2HAW A;  1WPN A;  4PY9 A;  2QB6 A;  2ZXP A;  1K20 A;  1K23 A;  2QB7 A;  4RPA A;  1IR6 A;  2ZXR A;  2ZXO A;  1WPM A;  1WPP A;  2EB0 A;  2ENX A;  1I74 A; 
#chains in the Genus database with same CATH topology
 1U1V A;  1SDJ A;  1U0K A;  4IK0 A;  2AZP A;  2YMA A;  3PVH A;  5GL3 A;  1XUA A;  2HAW A;  3EKM A;  4PY9 A;  2ZXP A;  1YM5 A;  4OA3 A;  2Q9J A;  1K20 A;  4RPA A;  1IR6 A;  1I74 A;  2QB8 A;  2GKE A;  3W5W A;  4K7X A;  4JBD A;  2OTN A;  5GKX A;  3FVE A;  4JUU A;  4K8L A;  4LS9 A;  1T6K A;  3WQZ A;  1XUB A;  2ZVF A;  2QB7 A;  4DUN A;  1WPP A;  4JD7 A;  2KPT A;  2Q9H A;  4FC5 A;  4Q60 A;  2IW4 A;  3DEV A;  4K7G B;  1WPN A;  4J9W A;  5GL4 A;  5M47 A;  1TM0 A;  5GL2 A;  2LT2 A;  4GL6 A;  1U1X A;  5HA4 A;  1BWZ A;  1W61 A;  5H2Y A;  2PVZ A;  1S7J A;  2ZXR A;  1WPM A;  2EB0 A;  2H9F A;  3ICJ A;  1W62 A;  4JCI A;  4IJZ A;  3PTJ A;  4Q2H A;  3EDN A;  4LB0 A;  4J9X A;  5IWE A;  1QYA A;  3EJX A;  3PW9 A;  1U1W A;  1GQZ A;  3G98 A;  2QB6 A;  2GKJ A;  2MPB A;  2PW0 A;  4DWZ A;  3IGH X;  5ANP A;  5H2G A;  1K23 A;  3G7K A;  4LG3 A;  2ZXO A;  1QY9 A;  2ENX A;  2KW7 A; 
#chains in the Genus database with same CATH homology
 1U1V A;  1SDJ A;  1U0K A;  4IK0 A;  2AZP A;  2YMA A;  3PVH A;  5GL3 A;  1XUA A;  2HAW A;  3EKM A;  4PY9 A;  2ZXP A;  1YM5 A;  4OA3 A;  2Q9J A;  1K20 A;  4RPA A;  1IR6 A;  1I74 A;  2QB8 A;  2GKE A;  3W5W A;  4K7X A;  4JBD A;  2OTN A;  5GKX A;  3FVE A;  4JUU A;  4K8L A;  4LS9 A;  1T6K A;  3WQZ A;  1XUB A;  2ZVF A;  2QB7 A;  4DUN A;  1WPP A;  4JD7 A;  2KPT A;  2Q9H A;  4FC5 A;  4Q60 A;  2IW4 A;  3DEV A;  4K7G B;  1WPN A;  4J9W A;  5GL4 A;  5M47 A;  1TM0 A;  5GL2 A;  2LT2 A;  4GL6 A;  1U1X A;  5HA4 A;  1BWZ A;  1W61 A;  5H2Y A;  2PVZ A;  1S7J A;  2ZXR A;  1WPM A;  2EB0 A;  2H9F A;  3ICJ A;  1W62 A;  4JCI A;  4IJZ A;  3PTJ A;  4Q2H A;  3EDN A;  4LB0 A;  4J9X A;  5IWE A;  1QYA A;  3EJX A;  3PW9 A;  1U1W A;  1GQZ A;  3G98 A;  2QB6 A;  2GKJ A;  2MPB A;  2PW0 A;  4DWZ A;  3IGH X;  5ANP A;  5H2G A;  1K23 A;  3G7K A;  4LG3 A;  2ZXO A;  1QY9 A;  2ENX A;  2KW7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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