4LS9A

Structure of mycobacterial nrna homolog reveals multifunctional nuclease activities
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
319
structure length
319
Chain Sequence
GARVDARGAADLLTAASSVSVICHVYPDADTIGAGLALAQVLAASGKHVEVSFATPAQLPESLQSLPGGHLLVAPEAMRRDADLVVTVDIPSINRLGALSGLAGPGREVLVIDHHASNQLFGTANYIDPSADSTTMLVAELLDAWGKPIDEKVAHCLYAGLTTDTGSFRWATARAHRLAARLVELGVDNASISRTLLDTHPFAWLPMLSRVLATARLLPDALDGRGFVYAVVPHDEWSEARPEEVESIVDIVRTTQQAEVAAVFKEIEPMHWSVSMRAKSVNLASVASAFGGGGHPHAAGYSATGSADDVVQALARALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Unique subunit packing in mycobacterial nanoRNase leads to alternate substrate recognitions in DHH phosphodiesterases
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium smegmatis
molecule keywords DHH family protein
total genus 105
structure length 319
sequence length 319
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01368 DHH DHH family
A PF02272 DHHA1 DHHA1 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.310.30 Alpha Beta Roll Diaminopimelate Epimerase; Chain A, domain 1 Diaminopimelate Epimerase; Chain A, domain 1 4ls9A02
3.90.1640.10 Alpha Beta Alpha-Beta Complex inorganic pyrophosphatase (n-terminal core) inorganic pyrophosphatase (n-terminal core) 4ls9A01
2ZXRA 4RPAA 2ZXPA 3DEVA 3W5WA 4PY9A 1K23A 2EB0A 2QB6A 1WPPA 2ENXA 2HAWA 1I74A 2ZXOA 1K20A 1WPMA 2QB7A 1WPNA 4LS9A 2QB8A 1IR6A 2IW4A
chains in the Genus database with same CATH superfamily
4K8LA 5IWEA 4LB0A 5M47A 2EB0A 4K7XA 4GL6A 2HAWA 4OA3A 4K7GB 2Q9HA 5GL2A 3EDNA 5H2YA 3EJXA 4LS9A 3IGHX 4FC5A 2ZXRA 1T6KA 3PTJA 5GKXA 2QB6A 3G98A 1YM5A 1GQZA 2Q9JA 1S7JA 3G7KA 1BWZA 5GL4A 2GKEA 1U0KA 1K20A 2ZXOA 4J9WA 1WPMA 1QYAA 5HA4A 2H9FA 5GL3A 1WPNA 3EKMA 4J9XA 2QB8A 4Q60A 1IR6A 2MPBA 1U1XA 2IW4A 4DUNA 4Q2HA 2AZPA 3DEVA 4IK0A 1W61A 2PVZA 2GKJA 2ENXA 2KPTA 3FVEA 4IJZA 1TM0A 4JBDA 1XUAA 2OTNA 2KW7A 2QB7A 4JCIA 3WQZA 2PW0A 1XUBA 4LG3A 1W62A 1U1VA 1SDJA 4JUUA 4RPAA 3ICJA 3PVHA 2ZXPA 3W5WA 1K23A 4PY9A 4DWZA 1WPPA 2LT2A 1U1WA 1I74A 5ANPA 2YMAA 2ZVFA 1QY9A 5H2GA 3PW9A 4JD7A
chains in the Genus database with same CATH topology
4K8LA 5IWEA 4LB0A 5M47A 2EB0A 4K7XA 4GL6A 2HAWA 4OA3A 4K7GB 2Q9HA 5GL2A 3EDNA 5H2YA 3EJXA 4LS9A 3IGHX 4FC5A 2ZXRA 1T6KA 3PTJA 5GKXA 2QB6A 3G98A 1YM5A 1GQZA 2Q9JA 1S7JA 3G7KA 1BWZA 5GL4A 2GKEA 1U0KA 1K20A 2ZXOA 4J9WA 1WPMA 1QYAA 5HA4A 2H9FA 5GL3A 1WPNA 3EKMA 4J9XA 2QB8A 4Q60A 1IR6A 2MPBA 1U1XA 2IW4A 4DUNA 4Q2HA 2AZPA 3DEVA 4IK0A 1W61A 2PVZA 2GKJA 2ENXA 2KPTA 3FVEA 4IJZA 1TM0A 4JBDA 1XUAA 2OTNA 2KW7A 2QB7A 4JCIA 3WQZA 2PW0A 1XUBA 4LG3A 1W62A 1U1VA 1SDJA 4JUUA 4RPAA 3ICJA 3PVHA 2ZXPA 3W5WA 1K23A 4PY9A 4DWZA 1WPPA 2LT2A 1U1WA 1I74A 5ANPA 2YMAA 2ZVFA 1QY9A 5H2GA 3PW9A 4JD7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZXR A;  4RPA A;  2ZXP A;  3DEV A;  3W5W A;  4PY9 A;  1K23 A;  2EB0 A;  2QB6 A;  1WPP A;  2ENX A;  2HAW A;  1I74 A;  2ZXO A;  1K20 A;  1WPM A;  2QB7 A;  1WPN A;  4LS9 A;  2QB8 A;  1IR6 A;  2IW4 A; 
#chains in the Genus database with same CATH topology
 4K8L A;  5IWE A;  4LB0 A;  5M47 A;  2EB0 A;  4K7X A;  4GL6 A;  2HAW A;  4OA3 A;  4K7G B;  2Q9H A;  5GL2 A;  3EDN A;  5H2Y A;  3EJX A;  4LS9 A;  3IGH X;  4FC5 A;  2ZXR A;  1T6K A;  3PTJ A;  5GKX A;  2QB6 A;  3G98 A;  1YM5 A;  1GQZ A;  2Q9J A;  1S7J A;  3G7K A;  1BWZ A;  5GL4 A;  2GKE A;  1U0K A;  1K20 A;  2ZXO A;  4J9W A;  1WPM A;  1QYA A;  5HA4 A;  2H9F A;  5GL3 A;  1WPN A;  3EKM A;  4J9X A;  2QB8 A;  4Q60 A;  1IR6 A;  2MPB A;  1U1X A;  2IW4 A;  4DUN A;  4Q2H A;  2AZP A;  3DEV A;  4IK0 A;  1W61 A;  2PVZ A;  2GKJ A;  2ENX A;  2KPT A;  3FVE A;  4IJZ A;  1TM0 A;  4JBD A;  1XUA A;  2OTN A;  2KW7 A;  2QB7 A;  4JCI A;  3WQZ A;  2PW0 A;  1XUB A;  4LG3 A;  1W62 A;  1U1V A;  1SDJ A;  4JUU A;  4RPA A;  3ICJ A;  3PVH A;  2ZXP A;  3W5W A;  1K23 A;  4PY9 A;  4DWZ A;  1WPP A;  2LT2 A;  1U1W A;  1I74 A;  5ANP A;  2YMA A;  2ZVF A;  1QY9 A;  5H2G A;  3PW9 A;  4JD7 A; 
#chains in the Genus database with same CATH homology
 4K8L A;  5IWE A;  4LB0 A;  5M47 A;  2EB0 A;  4K7X A;  4GL6 A;  2HAW A;  4OA3 A;  4K7G B;  2Q9H A;  5GL2 A;  3EDN A;  5H2Y A;  3EJX A;  4LS9 A;  3IGH X;  4FC5 A;  2ZXR A;  1T6K A;  3PTJ A;  5GKX A;  2QB6 A;  3G98 A;  1YM5 A;  1GQZ A;  2Q9J A;  1S7J A;  3G7K A;  1BWZ A;  5GL4 A;  2GKE A;  1U0K A;  1K20 A;  2ZXO A;  4J9W A;  1WPM A;  1QYA A;  5HA4 A;  2H9F A;  5GL3 A;  1WPN A;  3EKM A;  4J9X A;  2QB8 A;  4Q60 A;  1IR6 A;  2MPB A;  1U1X A;  2IW4 A;  4DUN A;  4Q2H A;  2AZP A;  3DEV A;  4IK0 A;  1W61 A;  2PVZ A;  2GKJ A;  2ENX A;  2KPT A;  3FVE A;  4IJZ A;  1TM0 A;  4JBD A;  1XUA A;  2OTN A;  2KW7 A;  2QB7 A;  4JCI A;  3WQZ A;  2PW0 A;  1XUB A;  4LG3 A;  1W62 A;  1U1V A;  1SDJ A;  4JUU A;  4RPA A;  3ICJ A;  3PVH A;  2ZXP A;  3W5W A;  1K23 A;  4PY9 A;  4DWZ A;  1WPP A;  2LT2 A;  1U1W A;  1I74 A;  5ANP A;  2YMA A;  2ZVF A;  1QY9 A;  5H2G A;  3PW9 A;  4JD7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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