4RPAA

Crystal structure of inorganic pyrophosphatase from staphylococcus aureus in complex with mn2+
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
308
structure length
306
Chain Sequence
AKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVSAETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIANFETAGPLYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTTQQDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of inorganic pyrophosphatase from Staphylococcus aureus reveals conformational flexibility of the active site.
pubmed doi rcsb
molecule tags Hydrolase
source organism Staphylococcus aureus
molecule keywords Probable manganese-dependent inorganic pyrophosphatase
total genus 98
structure length 306
sequence length 308
chains with identical sequence B
ec nomenclature ec 3.6.1.1: Inorganic diphosphatase.
pdb deposition date 2014-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01368 DHH DHH family
A PF02833 DHHA2 DHHA2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.310.20 Alpha Beta Roll Diaminopimelate Epimerase; Chain A, domain 1 Diaminopimelate Epimerase; Chain A, domain 1 4rpaA02
3.90.1640.10 Alpha Beta Alpha-Beta Complex inorganic pyrophosphatase (n-terminal core) inorganic pyrophosphatase (n-terminal core) 4rpaA01
2QB8A 1K23A 2IW4A 4LS9A 3W5WA 2HAWA 1K20A 4RPAA 2ENXA 2QB7A 2EB0A 1WPMA 2QB6A 1WPNA 4PY9A 3DEVA 1I74A 1WPPA
chains in the Genus database with same CATH superfamily
1XUBA 1BWZA 5ANPA 2LT2A 1WPMA 3EDNA 2KW7A 3PW9A 2GKEA 1K23A 2GKJA 4JUUA 4Q2HA 1U1WA 3G7KA 2Q9JA 4DWZA 5GL4A 1W61A 4K8LA 2PW0A 1U0KA 2PVZA 2HAWA 2EB0A 2H9FA 3IGHX 1YM5A 3G98A 4DUNA 1K20A 4RPAA 3FVEA 2ZXPA 4Q60A 1WPPA 1SDJA 2ZXRA 4K7GB 4LS9A 3PTJA 1XUAA 3PVHA 4J9WA 2ENXA 5GL2A 4FC5A 1QY9A 3DEVA 5H2YA 2QB8A 2OTNA 1U1XA 5GL3A 4J9XA 5M47A 5IWEA 3EKMA 4GL6A 4PY9A 1TM0A 4IK0A 5H2GA 4OA3A 1WPNA 2KPTA 1IR6A 5GKXA 4LB0A 3WQZA 3ICJA 1U1VA 2MPBA 4JD7A 4LG3A 2AZPA 2Q9HA 4IJZA 4JBDA 2ZXOA 4JCIA 2QB7A 2ZVFA 1I74A 3EJXA 5HA4A 1S7JA 2IW4A 1W62A 1T6KA 4K7XA 1GQZA 2YMAA 3W5WA 1QYAA 2QB6A
chains in the Genus database with same CATH topology
1XUBA 1BWZA 5ANPA 2LT2A 1WPMA 3EDNA 2KW7A 3PW9A 2GKEA 1K23A 2GKJA 4JUUA 4Q2HA 1U1WA 3G7KA 2Q9JA 4DWZA 5GL4A 1W61A 4K8LA 2PW0A 1U0KA 2PVZA 2HAWA 2EB0A 2H9FA 3IGHX 1YM5A 3G98A 4DUNA 1K20A 4RPAA 3FVEA 2ZXPA 4Q60A 1WPPA 1SDJA 2ZXRA 4K7GB 4LS9A 3PTJA 1XUAA 3PVHA 4J9WA 2ENXA 5GL2A 4FC5A 1QY9A 3DEVA 5H2YA 2QB8A 2OTNA 1U1XA 5GL3A 4J9XA 5M47A 5IWEA 3EKMA 4GL6A 4PY9A 1TM0A 4IK0A 5H2GA 4OA3A 1WPNA 2KPTA 1IR6A 5GKXA 4LB0A 3WQZA 3ICJA 1U1VA 2MPBA 4JD7A 4LG3A 2AZPA 2Q9HA 4IJZA 4JBDA 2ZXOA 4JCIA 2QB7A 2ZVFA 1I74A 3EJXA 5HA4A 1S7JA 2IW4A 1W62A 1T6KA 4K7XA 1GQZA 2YMAA 3W5WA 1QYAA 2QB6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QB8 A;  1K23 A;  2IW4 A;  4LS9 A;  3W5W A;  2HAW A;  1K20 A;  4RPA A;  2ENX A;  2QB7 A;  2EB0 A;  1WPM A;  2QB6 A;  1WPN A;  4PY9 A;  3DEV A;  1I74 A;  1WPP A; 
#chains in the Genus database with same CATH topology
 1XUB A;  1BWZ A;  5ANP A;  2LT2 A;  1WPM A;  3EDN A;  2KW7 A;  3PW9 A;  2GKE A;  1K23 A;  2GKJ A;  4JUU A;  4Q2H A;  1U1W A;  3G7K A;  2Q9J A;  4DWZ A;  5GL4 A;  1W61 A;  4K8L A;  2PW0 A;  1U0K A;  2PVZ A;  2HAW A;  2EB0 A;  2H9F A;  3IGH X;  1YM5 A;  3G98 A;  4DUN A;  1K20 A;  4RPA A;  3FVE A;  2ZXP A;  4Q60 A;  1WPP A;  1SDJ A;  2ZXR A;  4K7G B;  4LS9 A;  3PTJ A;  1XUA A;  3PVH A;  4J9W A;  2ENX A;  5GL2 A;  4FC5 A;  1QY9 A;  3DEV A;  5H2Y A;  2QB8 A;  2OTN A;  1U1X A;  5GL3 A;  4J9X A;  5M47 A;  5IWE A;  3EKM A;  4GL6 A;  4PY9 A;  1TM0 A;  4IK0 A;  5H2G A;  4OA3 A;  1WPN A;  2KPT A;  1IR6 A;  5GKX A;  4LB0 A;  3WQZ A;  3ICJ A;  1U1V A;  2MPB A;  4JD7 A;  4LG3 A;  2AZP A;  2Q9H A;  4IJZ A;  4JBD A;  2ZXO A;  4JCI A;  2QB7 A;  2ZVF A;  1I74 A;  3EJX A;  5HA4 A;  1S7J A;  2IW4 A;  1W62 A;  1T6K A;  4K7X A;  1GQZ A;  2YMA A;  3W5W A;  1QYA A;  2QB6 A; 
#chains in the Genus database with same CATH homology
 1XUB A;  1BWZ A;  5ANP A;  2LT2 A;  1WPM A;  3EDN A;  2KW7 A;  3PW9 A;  2GKE A;  1K23 A;  2GKJ A;  4JUU A;  4Q2H A;  1U1W A;  3G7K A;  2Q9J A;  4DWZ A;  5GL4 A;  1W61 A;  4K8L A;  2PW0 A;  1U0K A;  2PVZ A;  2HAW A;  2EB0 A;  2H9F A;  3IGH X;  1YM5 A;  3G98 A;  4DUN A;  1K20 A;  4RPA A;  3FVE A;  2ZXP A;  4Q60 A;  1WPP A;  1SDJ A;  2ZXR A;  4K7G B;  4LS9 A;  3PTJ A;  1XUA A;  3PVH A;  4J9W A;  2ENX A;  5GL2 A;  4FC5 A;  1QY9 A;  3DEV A;  5H2Y A;  2QB8 A;  2OTN A;  1U1X A;  5GL3 A;  4J9X A;  5M47 A;  5IWE A;  3EKM A;  4GL6 A;  4PY9 A;  1TM0 A;  4IK0 A;  5H2G A;  4OA3 A;  1WPN A;  2KPT A;  1IR6 A;  5GKX A;  4LB0 A;  3WQZ A;  3ICJ A;  1U1V A;  2MPB A;  4JD7 A;  4LG3 A;  2AZP A;  2Q9H A;  4IJZ A;  4JBD A;  2ZXO A;  4JCI A;  2QB7 A;  2ZVF A;  1I74 A;  3EJX A;  5HA4 A;  1S7J A;  2IW4 A;  1W62 A;  1T6K A;  4K7X A;  1GQZ A;  2YMA A;  3W5W A;  1QYA A;  2QB6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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