4YSYD

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with n-[(2,4-dichlorophenyl)methyl]-2-(trifluoromethyl)benzamide
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 39
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4ysyD00
3P4RC 4YT0D 3P4SD 3VR8D 3P4PC 2FBWC 1YQ3C 2BS2C 1L0VC 3AE8C 3VRAC 3CIRC 2WS3D 1ZP0C 3AEBD 3ABVD 3AE3C 3AEAD 4YTNC 3AE7D 3AE5C 2WQYD 2WU5D 3P4RD 1YQ4C 2B76C 1KF6C 3AE2C 1NEKC 3AEGC 3P4PD 2FBWD 1YQ3D 3VR9C 1L0VD 1NENC 1QLBC 3AE8D 4YSXC 3AEDD 2WP9C 3CIRD 3VRAD 4YSZC 2H88C 1ZP0D 3AE1C 3AE3D 2BS3C 2WDVC 3SFDC 4YTND 3AE5D 3AEFC 1ZOYD 4YTPC 4YSYC 1YQ4D 2B76D 1KF6D 1NEKD 3AE2D 3AEGD 3AEEC 3VR9D 1NEND 4YSXD 2WP9D 3AE4C 2H88D 3AE1D 2WDVD 5C2TC 3SFDD 3AEFD 3AE9C 4YTMC 4YSYD 4YTPD 3SFEC 4KX6C 3VRBC 5C3JC 3AEED 2H89C 3AE6C 3AE4D 3AECC 3P4QC 5C2TD 2WU2C 1KFYC 4YSZD 4YXDC 3AE9D 1E7PC 2ACZC 2WDQC 2WDRC 4YTMD 4YT0C 3P4SC 3AEDC 3VR8C 3SFED 4KX6D 5C3JD 3VRBD 2H89D 3AE6D 2BS4C 2WS3C 3AECD 3P4QD 3AEBC 1ZOYC 3ABVC 2WU2D 1KFYD 3AEAC 3AE7C 4YXDD 2WQYC 2WU5C 2ACZD 2WDQD 2WDRD
chains in the Genus database with same CATH superfamily
3P4RC 4YT0D 4DHJA 3P4SD 3VR8D 3P4PC 2FBWC 1YQ3C 2BS2C 1L0VC 3AE8C 3VRAC 3CIRC 2WS3D 1ZP0C 3AEBD 3ABVD 3AE3C 3AEAD 4YTNC 3AE7D 3AE5C 2WQYD 2WU5D 3P4RD 4I6LA 1YQ4C 2B76C 3VONA 1KF6C 3AE2C 1NEKC 3AEGC 3P4PD 2FBWD 1YQ3D 3VR9C 1L0VD 1NENC 1QLBC 3AE8D 1TFFA 3AEDD 2WP9C 3CIRD 4YSXC 3VRAD 4YSZC 2H88C 1ZP0D 4DDGA 3AE1C 3AE3D 2BS3C 2WDVC 3SFDC 4YTND 3AE5D 3AEFC 4FJVA 1ZOYD 4YTPC 4YSYC 1YQ4D 2B76D 1KF6D 1NEKD 3AE2D 3AEGD 3AEEC 3VR9D 4LDTA 1NEND 4YSXD 2WP9D 3AE4C 2H88D 3AE1D 2WDVD 5C2TC 3SFDD 3AEFD 3AE9C 4YTMC 4YSYD 4YTPD 3SFEC 4KX6C 3VRBC 5C3JC 3AEED 2H89C 3AE6C 4DHIB 3AE4D 3AECC 3P4QC 5C2TD 2ZFYA 2WU2C 1KFYC 4YSZD 4YXDC 3AE9D 1E7PC 2ACZC 2WDQC 2WDRC 4YTMD 4YT0C 3P4SC 3AEDC 3VR8C 3SFED 4KX6D 5C3JD 3VRBD 2H89D 4DHZA 3AE6D 2BS4C 2WS3C 3AECD 3P4QD 3AEBC 1ZOYC 3ABVC 2WU2D 1KFYD 3AEAC 4DDIA 3AE7C 4YXDD 2WQYC 2WU5C 2ACZD 2WDQD 2WDRD
chains in the Genus database with same CATH topology
3P4RC 4YT0D 3P4SD 3VR8D 3P4PC 2FBWC 1YQ3C 2BS2C 1L0VC 3AE8C 3VRAC 3CIRC 2WS3D 1ZP0C 3AEBD 3ABVD 3AE3C 3AEAD 4YTNC 3AE7D 3AE5C 2WQYD 2WU5D 3P4RD 1YQ4C 2B76C 1KF6C 3AE2C 1NEKC 3AEGC 3P4PD 2FBWD 1YQ3D 3VR9C 1L0VD 1NENC 1QLBC 3AE8D 4YSXC 3AEDD 2WP9C 3CIRD 3VRAD 4YSZC 2H88C 1ZP0D 3AE1C 3AE3D 2BS3C 2WDVC 3SFDC 4YTND 3AE5D 3AEFC 1ZOYD 4YTPC 4YSYC 1YQ4D 2B76D 1KF6D 1NEKD 3AE2D 3AEGD 3AEEC 3VR9D 1NEND 4YSXD 2WP9D 3AE4C 2H88D 3AE1D 2WDVD 5C2TC 3SFDD 3AEFD 3AE9C 4YTMC 4YSYD 4YTPD 3SFEC 4KX6C 3VRBC 5C3JC 3AEED 2H89C 3AE6C 3AE4D 3AECC 3P4QC 5C2TD 2WU2C 1KFYC 4YSZD 4YXDC 3AE9D 1E7PC 2ACZC 2WDQC 2WDRC 4YTMD 4YT0C 3P4SC 3AEDC 3VR8C 3SFED 4KX6D 5C3JD 3VRBD 2H89D 3AE6D 2BS4C 2WS3C 3AECD 3P4QD 3AEBC 1ZOYC 3ABVC 2WU2D 1KFYD 3AEAC 3AE7C 4YXDD 2WQYC 2WU5C 2ACZD 2WDQD 2WDRD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P4R C;  4YT0 D;  3P4S D;  3VR8 D;  3P4P C;  2FBW C;  1YQ3 C;  2BS2 C;  1L0V C;  3AE8 C;  3VRA C;  3CIR C;  2WS3 D;  1ZP0 C;  3AEB D;  3ABV D;  3AE3 C;  3AEA D;  4YTN C;  3AE7 D;  3AE5 C;  2WQY D;  2WU5 D;  3P4R D;  1YQ4 C;  2B76 C;  1KF6 C;  3AE2 C;  1NEK C;  3AEG C;  3P4P D;  2FBW D;  1YQ3 D;  3VR9 C;  1L0V D;  1NEN C;  1QLB C;  3AE8 D;  4YSX C;  3AED D;  2WP9 C;  3CIR D;  3VRA D;  4YSZ C;  2H88 C;  1ZP0 D;  3AE1 C;  3AE3 D;  2BS3 C;  2WDV C;  3SFD C;  4YTN D;  3AE5 D;  3AEF C;  1ZOY D;  4YTP C;  4YSY C;  1YQ4 D;  2B76 D;  1KF6 D;  1NEK D;  3AE2 D;  3AEG D;  3AEE C;  3VR9 D;  1NEN D;  4YSX D;  2WP9 D;  3AE4 C;  2H88 D;  3AE1 D;  2WDV D;  5C2T C;  3SFD D;  3AEF D;  3AE9 C;  4YTM C;  4YSY D;  4YTP D;  3SFE C;  4KX6 C;  3VRB C;  5C3J C;  3AEE D;  2H89 C;  3AE6 C;  3AE4 D;  3AEC C;  3P4Q C;  5C2T D;  2WU2 C;  1KFY C;  4YSZ D;  4YXD C;  3AE9 D;  1E7P C;  2ACZ C;  2WDQ C;  2WDR C;  4YTM D;  4YT0 C;  3P4S C;  3AED C;  3VR8 C;  3SFE D;  4KX6 D;  5C3J D;  3VRB D;  2H89 D;  3AE6 D;  2BS4 C;  2WS3 C;  3AEC D;  3P4Q D;  3AEB C;  1ZOY C;  3ABV C;  2WU2 D;  1KFY D;  3AEA C;  3AE7 C;  4YXD D;  2WQY C;  2WU5 C;  2ACZ D;  2WDQ D;  2WDR D; 
#chains in the Genus database with same CATH topology
 3P4R C;  4YT0 D;  4DHJ A;  3P4S D;  3VR8 D;  3P4P C;  2FBW C;  1YQ3 C;  2BS2 C;  1L0V C;  3AE8 C;  3VRA C;  3CIR C;  2WS3 D;  1ZP0 C;  3AEB D;  3ABV D;  3AE3 C;  3AEA D;  4YTN C;  3AE7 D;  3AE5 C;  2WQY D;  2WU5 D;  3P4R D;  4I6L A;  1YQ4 C;  2B76 C;  3VON A;  1KF6 C;  3AE2 C;  1NEK C;  3AEG C;  3P4P D;  2FBW D;  1YQ3 D;  3VR9 C;  1L0V D;  1NEN C;  1QLB C;  3AE8 D;  1TFF A;  3AED D;  2WP9 C;  3CIR D;  4YSX C;  3VRA D;  4YSZ C;  2H88 C;  1ZP0 D;  4DDG A;  3AE1 C;  3AE3 D;  2BS3 C;  2WDV C;  3SFD C;  4YTN D;  3AE5 D;  3AEF C;  4FJV A;  1ZOY D;  4YTP C;  4YSY C;  1YQ4 D;  2B76 D;  1KF6 D;  1NEK D;  3AE2 D;  3AEG D;  3AEE C;  3VR9 D;  4LDT A;  1NEN D;  4YSX D;  2WP9 D;  3AE4 C;  2H88 D;  3AE1 D;  2WDV D;  5C2T C;  3SFD D;  3AEF D;  3AE9 C;  4YTM C;  4YSY D;  4YTP D;  3SFE C;  4KX6 C;  3VRB C;  5C3J C;  3AEE D;  2H89 C;  3AE6 C;  4DHI B;  3AE4 D;  3AEC C;  3P4Q C;  5C2T D;  2ZFY A;  2WU2 C;  1KFY C;  4YSZ D;  4YXD C;  3AE9 D;  1E7P C;  2ACZ C;  2WDQ C;  2WDR C;  4YTM D;  4YT0 C;  3P4S C;  3AED C;  3VR8 C;  3SFE D;  4KX6 D;  5C3J D;  3VRB D;  2H89 D;  4DHZ A;  3AE6 D;  2BS4 C;  2WS3 C;  3AEC D;  3P4Q D;  3AEB C;  1ZOY C;  3ABV C;  2WU2 D;  1KFY D;  3AEA C;  4DDI A;  3AE7 C;  4YXD D;  2WQY C;  2WU5 C;  2ACZ D;  2WDQ D;  2WDR D; 
#chains in the Genus database with same CATH homology
 3P4R C;  4YT0 D;  3P4S D;  3VR8 D;  3P4P C;  2FBW C;  1YQ3 C;  2BS2 C;  1L0V C;  3AE8 C;  3VRA C;  3CIR C;  2WS3 D;  1ZP0 C;  3AEB D;  3ABV D;  3AE3 C;  3AEA D;  4YTN C;  3AE7 D;  3AE5 C;  2WQY D;  2WU5 D;  3P4R D;  1YQ4 C;  2B76 C;  1KF6 C;  3AE2 C;  1NEK C;  3AEG C;  3P4P D;  2FBW D;  1YQ3 D;  3VR9 C;  1L0V D;  1NEN C;  1QLB C;  3AE8 D;  4YSX C;  3AED D;  2WP9 C;  3CIR D;  3VRA D;  4YSZ C;  2H88 C;  1ZP0 D;  3AE1 C;  3AE3 D;  2BS3 C;  2WDV C;  3SFD C;  4YTN D;  3AE5 D;  3AEF C;  1ZOY D;  4YTP C;  4YSY C;  1YQ4 D;  2B76 D;  1KF6 D;  1NEK D;  3AE2 D;  3AEG D;  3AEE C;  3VR9 D;  1NEN D;  4YSX D;  2WP9 D;  3AE4 C;  2H88 D;  3AE1 D;  2WDV D;  5C2T C;  3SFD D;  3AEF D;  3AE9 C;  4YTM C;  4YSY D;  4YTP D;  3SFE C;  4KX6 C;  3VRB C;  5C3J C;  3AEE D;  2H89 C;  3AE6 C;  3AE4 D;  3AEC C;  3P4Q C;  5C2T D;  2WU2 C;  1KFY C;  4YSZ D;  4YXD C;  3AE9 D;  1E7P C;  2ACZ C;  2WDQ C;  2WDR C;  4YTM D;  4YT0 C;  3P4S C;  3AED C;  3VR8 C;  3SFE D;  4KX6 D;  5C3J D;  3VRB D;  2H89 D;  3AE6 D;  2BS4 C;  2WS3 C;  3AEC D;  3P4Q D;  3AEB C;  1ZOY C;  3ABV C;  2WU2 D;  1KFY D;  3AEA C;  3AE7 C;  4YXD D;  2WQY C;  2WU5 C;  2ACZ D;  2WDQ D;  2WDR D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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