4YSZC

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with 2-iodo-n-[3-(1-methylethoxy)phenyl]benzamide
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
153
structure length
153
Chain Sequence
EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 57
structure length 153
sequence length 153
chains with identical sequence G
ec nomenclature
pdb deposition date 2015-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01127 Sdh_cyt Succinate dehydrogenase/Fumarate reductase transmembrane subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4yszC00
3SFDC 4KX6D 2WDRC 3CIRC 1ZOYD 3AEGC 3AEAC 2WP9C 3AEDC 1YQ4C 4YTPC 2H88D 3AE4D 1KFYD 3AE8D 3AE6D 1NEKC 2WDVD 3P4RD 3P4QD 1L0VC 2BS3C 3AEBD 3AECC 3AE5D 5C2TD 4KX6C 2FBWD 3VR9D 3AE2D 2H89C 1ZOYC 1QLBC 3AE4C 1KFYC 3AE8C 4YTND 2WQYD 3AE9D 3P4RC 3P4QC 2ACZC 4YSZC 4YTMC 3VRBD 1ZP0C 5C2TC 4YSYC 2WDQD 2FBWC 3AE3D 3AEFC 2WU5D 2B76C 3AE7D 3AE1D 2BS2C 3P4PC 2WQYC 4YXDD 3SFED 3ABVD 2WDQC 3AEED 2WU2D 3VRAD 4YSXD 3AE3C 2H88C 2BS4C 3AE6C 2WDVC 1KF6D 3AE1C 3AEBC 3SFDD 3AE5C 2WDRD 4YT0D 3P4SD 4YXDC 3VR9C 3AE2C 2WP9D 3AEDD 1YQ4D 4YTPD 4YSXC 3VR8D 4YTNC 1E7PC 5C3JD 1YQ3D 3AE9C 1KF6C 3AECD 3VRBC 4YT0C 3P4SC 1NEND 2H89D 2WU5C 2WS3D 3AE7C 3VR8C 4YTMD 2ACZD 4YSZD 5C3JC 1YQ3C 3CIRD 1ZP0D 3AEGD 3SFEC 3AEAD 4YSYD 3ABVC 3AEFD 3AEEC 1NENC 2WU2C 3VRAC 1NEKD 2B76D 2WS3C 1L0VD 3P4PD
chains in the Genus database with same CATH superfamily
3SFDC 4KX6D 2WDRC 3CIRC 1ZOYD 3AEGC 3AEAC 2WP9C 2ZFYA 3AEDC 4I6LA 1YQ4C 4YTPC 2H88D 3AE4D 1KFYD 3AE8D 3AE6D 1NEKC 2WDVD 3P4RD 3P4QD 1L0VC 2BS3C 3AEBD 3AECC 3AE5D 5C2TD 4DHJA 4KX6C 2FBWD 3VR9D 3AE2D 2H89C 1ZOYC 1QLBC 3AE4C 1KFYC 3AE8C 4YTND 1TFFA 2WQYD 3AE9D 3P4RC 3P4QC 2ACZC 4YSZC 4YTMC 3VRBD 1ZP0C 5C2TC 4YSYC 2WDQD 2FBWC 3AE3D 3AEFC 2WU5D 4DDGA 4DDIA 2B76C 3AE7D 3AE1D 2BS2C 3P4PC 2WQYC 4YXDD 3SFED 3ABVD 2WDQC 3AEED 2WU2D 3VRAD 4YSXD 3AE3C 2H88C 2BS4C 3AE6C 2WDVC 1KF6D 3AE1C 3AEBC 3SFDD 3AE5C 2WDRD 4YT0D 3P4SD 4YXDC 3VR9C 3AE2C 2WP9D 3AEDD 1YQ4D 4YTPD 4YSXC 3VR8D 4YTNC 1E7PC 3VONA 5C3JD 1YQ3D 3AE9C 1KF6C 3AECD 4DHIB 4DHZA 3VRBC 4YT0C 3P4SC 1NEND 2H89D 2WU5C 4FJVA 2WS3D 3AE7C 3VR8C 4YTMD 2ACZD 4YSZD 5C3JC 1YQ3C 3CIRD 1ZP0D 3AEGD 3SFEC 3AEAD 4YSYD 3ABVC 3AEFD 3AEEC 1NENC 2WU2C 3VRAC 1NEKD 2B76D 2WS3C 1L0VD 3P4PD 4LDTA
chains in the Genus database with same CATH topology
3SFDC 4KX6D 2WDRC 3CIRC 1ZOYD 3AEGC 3AEAC 2WP9C 3AEDC 1YQ4C 4YTPC 2H88D 3AE4D 1KFYD 3AE8D 3AE6D 1NEKC 2WDVD 3P4RD 3P4QD 1L0VC 2BS3C 3AEBD 3AECC 3AE5D 5C2TD 4KX6C 2FBWD 3VR9D 3AE2D 2H89C 1ZOYC 1QLBC 3AE4C 1KFYC 3AE8C 4YTND 2WQYD 3AE9D 3P4RC 3P4QC 2ACZC 4YSZC 4YTMC 3VRBD 1ZP0C 5C2TC 4YSYC 2WDQD 2FBWC 3AE3D 3AEFC 2WU5D 2B76C 3AE7D 3AE1D 2BS2C 3P4PC 2WQYC 4YXDD 3SFED 3ABVD 2WDQC 3AEED 2WU2D 3VRAD 4YSXD 3AE3C 2H88C 2BS4C 3AE6C 2WDVC 1KF6D 3AE1C 3AEBC 3SFDD 3AE5C 2WDRD 4YT0D 3P4SD 4YXDC 3VR9C 3AE2C 2WP9D 3AEDD 1YQ4D 4YTPD 4YSXC 3VR8D 4YTNC 1E7PC 5C3JD 1YQ3D 3AE9C 1KF6C 3AECD 3VRBC 4YT0C 3P4SC 1NEND 2H89D 2WU5C 2WS3D 3AE7C 3VR8C 4YTMD 2ACZD 4YSZD 5C3JC 1YQ3C 3CIRD 1ZP0D 3AEGD 3SFEC 3AEAD 4YSYD 3ABVC 3AEFD 3AEEC 1NENC 2WU2C 3VRAC 1NEKD 2B76D 2WS3C 1L0VD 3P4PD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SFD C;  4KX6 D;  2WDR C;  3CIR C;  1ZOY D;  3AEG C;  3AEA C;  2WP9 C;  3AED C;  1YQ4 C;  4YTP C;  2H88 D;  3AE4 D;  1KFY D;  3AE8 D;  3AE6 D;  1NEK C;  2WDV D;  3P4R D;  3P4Q D;  1L0V C;  2BS3 C;  3AEB D;  3AEC C;  3AE5 D;  5C2T D;  4KX6 C;  2FBW D;  3VR9 D;  3AE2 D;  2H89 C;  1ZOY C;  1QLB C;  3AE4 C;  1KFY C;  3AE8 C;  4YTN D;  2WQY D;  3AE9 D;  3P4R C;  3P4Q C;  2ACZ C;  4YSZ C;  4YTM C;  3VRB D;  1ZP0 C;  5C2T C;  4YSY C;  2WDQ D;  2FBW C;  3AE3 D;  3AEF C;  2WU5 D;  2B76 C;  3AE7 D;  3AE1 D;  2BS2 C;  3P4P C;  2WQY C;  4YXD D;  3SFE D;  3ABV D;  2WDQ C;  3AEE D;  2WU2 D;  3VRA D;  4YSX D;  3AE3 C;  2H88 C;  2BS4 C;  3AE6 C;  2WDV C;  1KF6 D;  3AE1 C;  3AEB C;  3SFD D;  3AE5 C;  2WDR D;  4YT0 D;  3P4S D;  4YXD C;  3VR9 C;  3AE2 C;  2WP9 D;  3AED D;  1YQ4 D;  4YTP D;  4YSX C;  3VR8 D;  4YTN C;  1E7P C;  5C3J D;  1YQ3 D;  3AE9 C;  1KF6 C;  3AEC D;  3VRB C;  4YT0 C;  3P4S C;  1NEN D;  2H89 D;  2WU5 C;  2WS3 D;  3AE7 C;  3VR8 C;  4YTM D;  2ACZ D;  4YSZ D;  5C3J C;  1YQ3 C;  3CIR D;  1ZP0 D;  3AEG D;  3SFE C;  3AEA D;  4YSY D;  3ABV C;  3AEF D;  3AEE C;  1NEN C;  2WU2 C;  3VRA C;  1NEK D;  2B76 D;  2WS3 C;  1L0V D;  3P4P D; 
#chains in the Genus database with same CATH topology
 3SFD C;  4KX6 D;  2WDR C;  3CIR C;  1ZOY D;  3AEG C;  3AEA C;  2WP9 C;  2ZFY A;  3AED C;  4I6L A;  1YQ4 C;  4YTP C;  2H88 D;  3AE4 D;  1KFY D;  3AE8 D;  3AE6 D;  1NEK C;  2WDV D;  3P4R D;  3P4Q D;  1L0V C;  2BS3 C;  3AEB D;  3AEC C;  3AE5 D;  5C2T D;  4DHJ A;  4KX6 C;  2FBW D;  3VR9 D;  3AE2 D;  2H89 C;  1ZOY C;  1QLB C;  3AE4 C;  1KFY C;  3AE8 C;  4YTN D;  1TFF A;  2WQY D;  3AE9 D;  3P4R C;  3P4Q C;  2ACZ C;  4YSZ C;  4YTM C;  3VRB D;  1ZP0 C;  5C2T C;  4YSY C;  2WDQ D;  2FBW C;  3AE3 D;  3AEF C;  2WU5 D;  4DDG A;  4DDI A;  2B76 C;  3AE7 D;  3AE1 D;  2BS2 C;  3P4P C;  2WQY C;  4YXD D;  3SFE D;  3ABV D;  2WDQ C;  3AEE D;  2WU2 D;  3VRA D;  4YSX D;  3AE3 C;  2H88 C;  2BS4 C;  3AE6 C;  2WDV C;  1KF6 D;  3AE1 C;  3AEB C;  3SFD D;  3AE5 C;  2WDR D;  4YT0 D;  3P4S D;  4YXD C;  3VR9 C;  3AE2 C;  2WP9 D;  3AED D;  1YQ4 D;  4YTP D;  4YSX C;  3VR8 D;  4YTN C;  1E7P C;  3VON A;  5C3J D;  1YQ3 D;  3AE9 C;  1KF6 C;  3AEC D;  4DHI B;  4DHZ A;  3VRB C;  4YT0 C;  3P4S C;  1NEN D;  2H89 D;  2WU5 C;  4FJV A;  2WS3 D;  3AE7 C;  3VR8 C;  4YTM D;  2ACZ D;  4YSZ D;  5C3J C;  1YQ3 C;  3CIR D;  1ZP0 D;  3AEG D;  3SFE C;  3AEA D;  4YSY D;  3ABV C;  3AEF D;  3AEE C;  1NEN C;  2WU2 C;  3VRA C;  1NEK D;  2B76 D;  2WS3 C;  1L0V D;  3P4P D;  4LDT A; 
#chains in the Genus database with same CATH homology
 3SFD C;  4KX6 D;  2WDR C;  3CIR C;  1ZOY D;  3AEG C;  3AEA C;  2WP9 C;  3AED C;  1YQ4 C;  4YTP C;  2H88 D;  3AE4 D;  1KFY D;  3AE8 D;  3AE6 D;  1NEK C;  2WDV D;  3P4R D;  3P4Q D;  1L0V C;  2BS3 C;  3AEB D;  3AEC C;  3AE5 D;  5C2T D;  4KX6 C;  2FBW D;  3VR9 D;  3AE2 D;  2H89 C;  1ZOY C;  1QLB C;  3AE4 C;  1KFY C;  3AE8 C;  4YTN D;  2WQY D;  3AE9 D;  3P4R C;  3P4Q C;  2ACZ C;  4YSZ C;  4YTM C;  3VRB D;  1ZP0 C;  5C2T C;  4YSY C;  2WDQ D;  2FBW C;  3AE3 D;  3AEF C;  2WU5 D;  2B76 C;  3AE7 D;  3AE1 D;  2BS2 C;  3P4P C;  2WQY C;  4YXD D;  3SFE D;  3ABV D;  2WDQ C;  3AEE D;  2WU2 D;  3VRA D;  4YSX D;  3AE3 C;  2H88 C;  2BS4 C;  3AE6 C;  2WDV C;  1KF6 D;  3AE1 C;  3AEB C;  3SFD D;  3AE5 C;  2WDR D;  4YT0 D;  3P4S D;  4YXD C;  3VR9 C;  3AE2 C;  2WP9 D;  3AED D;  1YQ4 D;  4YTP D;  4YSX C;  3VR8 D;  4YTN C;  1E7P C;  5C3J D;  1YQ3 D;  3AE9 C;  1KF6 C;  3AEC D;  3VRB C;  4YT0 C;  3P4S C;  1NEN D;  2H89 D;  2WU5 C;  2WS3 D;  3AE7 C;  3VR8 C;  4YTM D;  2ACZ D;  4YSZ D;  5C3J C;  1YQ3 C;  3CIR D;  1ZP0 D;  3AEG D;  3SFE C;  3AEA D;  4YSY D;  3ABV C;  3AEF D;  3AEE C;  1NEN C;  2WU2 C;  3VRA C;  1NEK D;  2B76 D;  2WS3 C;  1L0V D;  3P4P D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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