4YSZ | Genus

Total Genus 40

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	40
sequence length	129
structure length	129
Chain Sequence	TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Oxidoreductase/oxidoreductase inhibitor
publication title	Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria pubmed doi rcsb
molecule keywords	Succinate dehydrogenase flavoprotein
total genus	40
structure length	129
sequence length	129
chains with identical sequence	H
ec nomenclature
pdb deposition date	2015-03-17

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
D	PF05328	CybS	CybS, succinate dehydrogenase cytochrome B small subunit

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.1300.10	Mainly Alpha	Up-down Bundle	3 helical TM bundles of succinate and fumarate reductases	Fumarate reductase/succinate dehydrogenase, transmembrane subunit	4yszD00

4YTPC 3AEFC 3AE5D 4YSZC 2WDVD 3VR9C 2WU5D 4YT0C 3AE1D 3AEBC 2WDQD 3ABVD 2H89C 3AE4C 3P4SC 3P4RD 1YQ3C 3AE9C 3SFEC 3AECC 2B76D 3AEED 3AEGD 4YSYC 3AE7C 3CIRC 3AEAC 1NENC 2WQYC 2H88D 2WDRC 3P4QC 3SFDC 3AE8C 1YQ4C 4YTMD 4YSXD 2WS3C 3AE4D 3P4SD 1YQ3D 1ZP0D 1KFYC 3AE6C 2ACZD 5C3JC 1ZOYC 3AE2D 5C2TC 3P4PC 3VRAD 3AEDD 3VR8C 4YTND 3AE3C 4KX6C 1NEKC 4YTPD 2WU2C 3AEFD 1L0VC 4YSZD 2BS2C 1KFYD 2BS3C 3VR9D 1KF6C 3P4PD 3VRBC 2WP9C 4YT0D 3AEBD 1E7PC 2H89D 3AE9D 3AE5C 3SFED 3AECD 4YSYD 2WDVC 3AE7D 3CIRD 3AEAD 1NEND 4YXDC 2WU5C 2WQYD 2WDRD 3P4QD 3SFDD 3P4RC 3AE8D 1YQ4D 2WS3D 2BS4C 2B76C 3AEEC 3AE6D 5C3JD 1ZOYD 2FBWC 5C2TD 3AEGC 2H88C 3VR8D 4YXDD 3AE3D 4KX6D 1NEKD 4YTMC 4YSXC 2WU2D 1L0VD 1ZP0C 2ACZC 3AE2C 2FBWD 1KF6D 3VRAC 3AE1C 2WDQC 3ABVC 3AEDC 2WP9D 3VRBD 1QLBC 4YTNC
chains in the Genus database with same CATH superfamily

4YTPC 3AEFC 2ZFYA 3AE5D 4YSZC 2WDVD 3VR9C 2WU5D 4YT0C 3AE1D 3AEBC 2WDQD 3ABVD 2H89C 3AE4C 3P4SC 3P4RD 1YQ3C 3AE9C 4I6LA 3SFEC 3AECC 2B76D 3AEED 3AEGD 4YSYC 3AE7C 3CIRC 3AEAC 1NENC 2WQYC 2H88D 2WDRC 3P4QC 3SFDC 4DDGA 3AE8C 1YQ4C 4YTMD 4DHZA 4YSXD 2WS3C 3AE4D 3P4SD 1YQ3D 1ZP0D 4DDIA 1KFYC 3AE6C 2ACZD 5C3JC 1ZOYC 3AE2D 5C2TC 4DHIB 3P4PC 4DHJA 3VRAD 3AEDD 4FJVA 3VR8C 4YTND 3AE3C 4KX6C 1NEKC 4YTPD 2WU2C 3AEFD 1L0VC 4YSZD 2BS2C 1KFYD 2BS3C 3VR9D 1KF6C 3P4PD 3VRBC 2WP9C 4YT0D 3AEBD 1E7PC 2H89D 3AE9D 3AE5C 3SFED 3AECD 4YSYD 2WDVC 3AE7D 3CIRD 3AEAD 1NEND 4LDTA 4YXDC 1TFFA 2WU5C 2WQYD 2WDRD 3P4QD 3SFDD 3P4RC 3AE8D 1YQ4D 2WS3D 2BS4C 2B76C 3AEEC 3AE6D 5C3JD 1ZOYD 2FBWC 5C2TD 3AEGC 2H88C 3VR8D 4YXDD 3AE3D 4KX6D 1NEKD 4YTMC 4YSXC 2WU2D 1L0VD 1ZP0C 2ACZC 3AE2C 3VONA 2FBWD 1KF6D 3VRAC 3AE1C 2WDQC 3ABVC 3AEDC 2WP9D 3VRBD 1QLBC 4YTNC
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4YTP C;  3AEF C;  3AE5 D;  4YSZ C;  2WDV D;  3VR9 C;  2WU5 D;  4YT0 C;  3AE1 D;  3AEB C;  2WDQ D;  3ABV D;  2H89 C;  3AE4 C;  3P4S C;  3P4R D;  1YQ3 C;  3AE9 C;  3SFE C;  3AEC C;  2B76 D;  3AEE D;  3AEG D;  4YSY C;  3AE7 C;  3CIR C;  3AEA C;  1NEN C;  2WQY C;  2H88 D;  2WDR C;  3P4Q C;  3SFD C;  3AE8 C;  1YQ4 C;  4YTM D;  4YSX D;  2WS3 C;  3AE4 D;  3P4S D;  1YQ3 D;  1ZP0 D;  1KFY C;  3AE6 C;  2ACZ D;  5C3J C;  1ZOY C;  3AE2 D;  5C2T C;  3P4P C;  3VRA D;  3AED D;  3VR8 C;  4YTN D;  3AE3 C;  4KX6 C;  1NEK C;  4YTP D;  2WU2 C;  3AEF D;  1L0V C;  4YSZ D;  2BS2 C;  1KFY D;  2BS3 C;  3VR9 D;  1KF6 C;  3P4P D;  3VRB C;  2WP9 C;  4YT0 D;  3AEB D;  1E7P C;  2H89 D;  3AE9 D;  3AE5 C;  3SFE D;  3AEC D;  4YSY D;  2WDV C;  3AE7 D;  3CIR D;  3AEA D;  1NEN D;  4YXD C;  2WU5 C;  2WQY D;  2WDR D;  3P4Q D;  3SFD D;  3P4R C;  3AE8 D;  1YQ4 D;  2WS3 D;  2BS4 C;  2B76 C;  3AEE C;  3AE6 D;  5C3J D;  1ZOY D;  2FBW C;  5C2T D;  3AEG C;  2H88 C;  3VR8 D;  4YXD D;  3AE3 D;  4KX6 D;  1NEK D;  4YTM C;  4YSX C;  2WU2 D;  1L0V D;  1ZP0 C;  2ACZ C;  3AE2 C;  2FBW D;  1KF6 D;  3VRA C;  3AE1 C;  2WDQ C;  3ABV C;  3AED C;  2WP9 D;  3VRB D;  1QLB C;  4YTN C; 
#chains in the Genus database with same CATH topology
 4YTP C;  3AEF C;  2ZFY A;  3AE5 D;  4YSZ C;  2WDV D;  3VR9 C;  2WU5 D;  4YT0 C;  3AE1 D;  3AEB C;  2WDQ D;  3ABV D;  2H89 C;  3AE4 C;  3P4S C;  3P4R D;  1YQ3 C;  3AE9 C;  4I6L A;  3SFE C;  3AEC C;  2B76 D;  3AEE D;  3AEG D;  4YSY C;  3AE7 C;  3CIR C;  3AEA C;  1NEN C;  2WQY C;  2H88 D;  2WDR C;  3P4Q C;  3SFD C;  4DDG A;  3AE8 C;  1YQ4 C;  4YTM D;  4DHZ A;  4YSX D;  2WS3 C;  3AE4 D;  3P4S D;  1YQ3 D;  1ZP0 D;  4DDI A;  1KFY C;  3AE6 C;  2ACZ D;  5C3J C;  1ZOY C;  3AE2 D;  5C2T C;  4DHI B;  3P4P C;  4DHJ A;  3VRA D;  3AED D;  4FJV A;  3VR8 C;  4YTN D;  3AE3 C;  4KX6 C;  1NEK C;  4YTP D;  2WU2 C;  3AEF D;  1L0V C;  4YSZ D;  2BS2 C;  1KFY D;  2BS3 C;  3VR9 D;  1KF6 C;  3P4P D;  3VRB C;  2WP9 C;  4YT0 D;  3AEB D;  1E7P C;  2H89 D;  3AE9 D;  3AE5 C;  3SFE D;  3AEC D;  4YSY D;  2WDV C;  3AE7 D;  3CIR D;  3AEA D;  1NEN D;  4LDT A;  4YXD C;  1TFF A;  2WU5 C;  2WQY D;  2WDR D;  3P4Q D;  3SFD D;  3P4R C;  3AE8 D;  1YQ4 D;  2WS3 D;  2BS4 C;  2B76 C;  3AEE C;  3AE6 D;  5C3J D;  1ZOY D;  2FBW C;  5C2T D;  3AEG C;  2H88 C;  3VR8 D;  4YXD D;  3AE3 D;  4KX6 D;  1NEK D;  4YTM C;  4YSX C;  2WU2 D;  1L0V D;  1ZP0 C;  2ACZ C;  3AE2 C;  3VON A;  2FBW D;  1KF6 D;  3VRA C;  3AE1 C;  2WDQ C;  3ABV C;  3AED C;  2WP9 D;  3VRB D;  1QLB C;  4YTN C; 
#chains in the Genus database with same CATH homology
 4YTP C;  3AEF C;  3AE5 D;  4YSZ C;  2WDV D;  3VR9 C;  2WU5 D;  4YT0 C;  3AE1 D;  3AEB C;  2WDQ D;  3ABV D;  2H89 C;  3AE4 C;  3P4S C;  3P4R D;  1YQ3 C;  3AE9 C;  3SFE C;  3AEC C;  2B76 D;  3AEE D;  3AEG D;  4YSY C;  3AE7 C;  3CIR C;  3AEA C;  1NEN C;  2WQY C;  2H88 D;  2WDR C;  3P4Q C;  3SFD C;  3AE8 C;  1YQ4 C;  4YTM D;  4YSX D;  2WS3 C;  3AE4 D;  3P4S D;  1YQ3 D;  1ZP0 D;  1KFY C;  3AE6 C;  2ACZ D;  5C3J C;  1ZOY C;  3AE2 D;  5C2T C;  3P4P C;  3VRA D;  3AED D;  3VR8 C;  4YTN D;  3AE3 C;  4KX6 C;  1NEK C;  4YTP D;  2WU2 C;  3AEF D;  1L0V C;  4YSZ D;  2BS2 C;  1KFY D;  2BS3 C;  3VR9 D;  1KF6 C;  3P4P D;  3VRB C;  2WP9 C;  4YT0 D;  3AEB D;  1E7P C;  2H89 D;  3AE9 D;  3AE5 C;  3SFE D;  3AEC D;  4YSY D;  2WDV C;  3AE7 D;  3CIR D;  3AEA D;  1NEN D;  4YXD C;  2WU5 C;  2WQY D;  2WDR D;  3P4Q D;  3SFD D;  3P4R C;  3AE8 D;  1YQ4 D;  2WS3 D;  2BS4 C;  2B76 C;  3AEE C;  3AE6 D;  5C3J D;  1ZOY D;  2FBW C;  5C2T D;  3AEG C;  2H88 C;  3VR8 D;  4YXD D;  3AE3 D;  4KX6 D;  1NEK D;  4YTM C;  4YSX C;  2WU2 D;  1L0V D;  1ZP0 C;  2ACZ C;  3AE2 C;  2FBW D;  1KF6 D;  3VRA C;  3AE1 C;  2WDQ C;  3ABV C;  3AED C;  2WP9 D;  3VRB D;  1QLB C;  4YTN C;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4YSZD

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations