4YSZD

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with 2-iodo-n-[3-(1-methylethoxy)phenyl]benzamide
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 40
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4yszD00
1ZOYD 2ACZD 2WU5D 3VR8D 1ZP0D 3VR9C 4YTND 3CIRC 2H88C 3AE1D 2WQYD 5C3JC 2B76D 3SFDD 3AEED 4YXDD 3AEBC 3VRAC 2WDQD 2WU2D 3AECC 4YT0C 3P4RC 4YTMD 2FBWD 3AEAC 4YT0D 2WS3C 3AEDD 3P4QD 3P4PC 3AEAD 1L0VD 1ZOYC 4YTPD 2WU5C 3VR8C 1QLBC 1ZP0C 3SFED 4YTNC 1KF6D 3AE1C 3P4SD 3AE4C 2WQYC 4YSZD 2B76C 2WDVD 3AE7D 3SFDC 3AEEC 4YXDC 3AE4D 2WDQC 2WU2C 4YSXD 4KX6D 3AE3D 3AE6D 4YTMC 2FBWC 3AEDC 3P4QC 1NEKD 1L0VC 3AEFD 1YQ4D 4YTPC 3AEGD 2BS4C 3AE5D 2WDRD 3SFEC 1KFYD 1KF6C 3P4SC 4YSZC 2WDVC 3AE7C 3AE8C 1NEND 3ABVD 2H89D 4YSXC 3AE8D 4KX6C 3AE6C 3AE3C 2WP9D 1NEKC 3AEFC 1YQ4C 3AEGC 3AE2D 3AE5C 2WDRC 2BS3C 1KFYC 3VRBD 1YQ3D 4YSYC 3AE9D 5C2TD 4YSYD 1NENC 3ABVC 2H89C 3VR9D 3CIRD 2H88D 2WP9C 5C3JD 3AEBD 3VRAD 3AECD 3AE2C 3P4RD 3VRBC 1YQ3C 2BS2C 2ACZC 2WS3D 1E7PC 3P4PD 3AE9C 5C2TC
chains in the Genus database with same CATH superfamily
1ZOYD 2ACZD 2WU5D 3VR8D 1ZP0D 3VR9C 4YTND 3CIRC 2H88C 3AE1D 2WQYD 5C3JC 2B76D 3SFDD 3AEED 4YXDD 3AEBC 3VRAC 2WDQD 2WU2D 3AECC 4YT0C 3P4RC 4YTMD 2FBWD 3AEAC 4YT0D 2WS3C 3AEDD 3P4QD 3P4PC 3AEAD 1L0VD 1ZOYC 4YTPD 2WU5C 3VR8C 1QLBC 1ZP0C 3SFED 4YTNC 3VONA 1KF6D 3AE1C 3P4SD 3AE4C 2WQYC 4YSZD 2B76C 2WDVD 3AE7D 3SFDC 3AEEC 4YXDC 3AE4D 2WDQC 2WU2C 4LDTA 4YSXD 4KX6D 3AE3D 3AE6D 4YTMC 2FBWC 3AEDC 3P4QC 4I6LA 1NEKD 1L0VC 3AEFD 1YQ4D 4DDGA 4YTPC 3AEGD 2BS4C 3AE5D 2WDRD 4FJVA 1KFYD 3SFEC 1KF6C 3P4SC 4YSZC 2WDVC 3AE7C 3AE8C 1NEND 3ABVD 2H89D 4YSXC 3AE8D 4KX6C 3AE6C 3AE3C 2WP9D 1TFFA 1NEKC 3AEFC 1YQ4C 3AEGC 3AE2D 3AE5C 2WDRC 2BS3C 1KFYC 3VRBD 1YQ3D 4YSYC 4DDIA 4DHZA 3AE9D 5C2TD 4YSYD 4DHIB 1NENC 3ABVC 2H89C 3VR9D 3CIRD 2H88D 2WP9C 5C3JD 3AEBD 3VRAD 2ZFYA 3AECD 3AE2C 3P4RD 4DHJA 3VRBC 1YQ3C 2BS2C 2ACZC 2WS3D 1E7PC 3P4PD 3AE9C 5C2TC
chains in the Genus database with same CATH topology
1ZOYD 2ACZD 2WU5D 3VR8D 1ZP0D 3VR9C 4YTND 3CIRC 2H88C 3AE1D 2WQYD 5C3JC 2B76D 3SFDD 3AEED 4YXDD 3AEBC 3VRAC 2WDQD 2WU2D 3AECC 4YT0C 3P4RC 4YTMD 2FBWD 3AEAC 4YT0D 2WS3C 3AEDD 3P4QD 3P4PC 3AEAD 1L0VD 1ZOYC 4YTPD 2WU5C 3VR8C 1QLBC 1ZP0C 3SFED 4YTNC 1KF6D 3AE1C 3P4SD 3AE4C 2WQYC 4YSZD 2B76C 2WDVD 3AE7D 3SFDC 3AEEC 4YXDC 3AE4D 2WDQC 2WU2C 4YSXD 4KX6D 3AE3D 3AE6D 4YTMC 2FBWC 3AEDC 3P4QC 1NEKD 1L0VC 3AEFD 1YQ4D 4YTPC 3AEGD 2BS4C 3AE5D 2WDRD 3SFEC 1KFYD 1KF6C 3P4SC 4YSZC 2WDVC 3AE7C 3AE8C 1NEND 3ABVD 2H89D 4YSXC 3AE8D 4KX6C 3AE6C 3AE3C 2WP9D 1NEKC 3AEFC 1YQ4C 3AEGC 3AE2D 3AE5C 2WDRC 2BS3C 1KFYC 3VRBD 1YQ3D 4YSYC 3AE9D 5C2TD 4YSYD 1NENC 3ABVC 2H89C 3VR9D 3CIRD 2H88D 2WP9C 5C3JD 3AEBD 3VRAD 3AECD 3AE2C 3P4RD 3VRBC 1YQ3C 2BS2C 2ACZC 2WS3D 1E7PC 3P4PD 3AE9C 5C2TC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZOY D;  2ACZ D;  2WU5 D;  3VR8 D;  1ZP0 D;  3VR9 C;  4YTN D;  3CIR C;  2H88 C;  3AE1 D;  2WQY D;  5C3J C;  2B76 D;  3SFD D;  3AEE D;  4YXD D;  3AEB C;  3VRA C;  2WDQ D;  2WU2 D;  3AEC C;  4YT0 C;  3P4R C;  4YTM D;  2FBW D;  3AEA C;  4YT0 D;  2WS3 C;  3AED D;  3P4Q D;  3P4P C;  3AEA D;  1L0V D;  1ZOY C;  4YTP D;  2WU5 C;  3VR8 C;  1QLB C;  1ZP0 C;  3SFE D;  4YTN C;  1KF6 D;  3AE1 C;  3P4S D;  3AE4 C;  2WQY C;  4YSZ D;  2B76 C;  2WDV D;  3AE7 D;  3SFD C;  3AEE C;  4YXD C;  3AE4 D;  2WDQ C;  2WU2 C;  4YSX D;  4KX6 D;  3AE3 D;  3AE6 D;  4YTM C;  2FBW C;  3AED C;  3P4Q C;  1NEK D;  1L0V C;  3AEF D;  1YQ4 D;  4YTP C;  3AEG D;  2BS4 C;  3AE5 D;  2WDR D;  3SFE C;  1KFY D;  1KF6 C;  3P4S C;  4YSZ C;  2WDV C;  3AE7 C;  3AE8 C;  1NEN D;  3ABV D;  2H89 D;  4YSX C;  3AE8 D;  4KX6 C;  3AE6 C;  3AE3 C;  2WP9 D;  1NEK C;  3AEF C;  1YQ4 C;  3AEG C;  3AE2 D;  3AE5 C;  2WDR C;  2BS3 C;  1KFY C;  3VRB D;  1YQ3 D;  4YSY C;  3AE9 D;  5C2T D;  4YSY D;  1NEN C;  3ABV C;  2H89 C;  3VR9 D;  3CIR D;  2H88 D;  2WP9 C;  5C3J D;  3AEB D;  3VRA D;  3AEC D;  3AE2 C;  3P4R D;  3VRB C;  1YQ3 C;  2BS2 C;  2ACZ C;  2WS3 D;  1E7P C;  3P4P D;  3AE9 C;  5C2T C; 
#chains in the Genus database with same CATH topology
 1ZOY D;  2ACZ D;  2WU5 D;  3VR8 D;  1ZP0 D;  3VR9 C;  4YTN D;  3CIR C;  2H88 C;  3AE1 D;  2WQY D;  5C3J C;  2B76 D;  3SFD D;  3AEE D;  4YXD D;  3AEB C;  3VRA C;  2WDQ D;  2WU2 D;  3AEC C;  4YT0 C;  3P4R C;  4YTM D;  2FBW D;  3AEA C;  4YT0 D;  2WS3 C;  3AED D;  3P4Q D;  3P4P C;  3AEA D;  1L0V D;  1ZOY C;  4YTP D;  2WU5 C;  3VR8 C;  1QLB C;  1ZP0 C;  3SFE D;  4YTN C;  3VON A;  1KF6 D;  3AE1 C;  3P4S D;  3AE4 C;  2WQY C;  4YSZ D;  2B76 C;  2WDV D;  3AE7 D;  3SFD C;  3AEE C;  4YXD C;  3AE4 D;  2WDQ C;  2WU2 C;  4LDT A;  4YSX D;  4KX6 D;  3AE3 D;  3AE6 D;  4YTM C;  2FBW C;  3AED C;  3P4Q C;  4I6L A;  1NEK D;  1L0V C;  3AEF D;  1YQ4 D;  4DDG A;  4YTP C;  3AEG D;  2BS4 C;  3AE5 D;  2WDR D;  4FJV A;  1KFY D;  3SFE C;  1KF6 C;  3P4S C;  4YSZ C;  2WDV C;  3AE7 C;  3AE8 C;  1NEN D;  3ABV D;  2H89 D;  4YSX C;  3AE8 D;  4KX6 C;  3AE6 C;  3AE3 C;  2WP9 D;  1TFF A;  1NEK C;  3AEF C;  1YQ4 C;  3AEG C;  3AE2 D;  3AE5 C;  2WDR C;  2BS3 C;  1KFY C;  3VRB D;  1YQ3 D;  4YSY C;  4DDI A;  4DHZ A;  3AE9 D;  5C2T D;  4YSY D;  4DHI B;  1NEN C;  3ABV C;  2H89 C;  3VR9 D;  3CIR D;  2H88 D;  2WP9 C;  5C3J D;  3AEB D;  3VRA D;  2ZFY A;  3AEC D;  3AE2 C;  3P4R D;  4DHJ A;  3VRB C;  1YQ3 C;  2BS2 C;  2ACZ C;  2WS3 D;  1E7P C;  3P4P D;  3AE9 C;  5C2T C; 
#chains in the Genus database with same CATH homology
 1ZOY D;  2ACZ D;  2WU5 D;  3VR8 D;  1ZP0 D;  3VR9 C;  4YTN D;  3CIR C;  2H88 C;  3AE1 D;  2WQY D;  5C3J C;  2B76 D;  3SFD D;  3AEE D;  4YXD D;  3AEB C;  3VRA C;  2WDQ D;  2WU2 D;  3AEC C;  4YT0 C;  3P4R C;  4YTM D;  2FBW D;  3AEA C;  4YT0 D;  2WS3 C;  3AED D;  3P4Q D;  3P4P C;  3AEA D;  1L0V D;  1ZOY C;  4YTP D;  2WU5 C;  3VR8 C;  1QLB C;  1ZP0 C;  3SFE D;  4YTN C;  1KF6 D;  3AE1 C;  3P4S D;  3AE4 C;  2WQY C;  4YSZ D;  2B76 C;  2WDV D;  3AE7 D;  3SFD C;  3AEE C;  4YXD C;  3AE4 D;  2WDQ C;  2WU2 C;  4YSX D;  4KX6 D;  3AE3 D;  3AE6 D;  4YTM C;  2FBW C;  3AED C;  3P4Q C;  1NEK D;  1L0V C;  3AEF D;  1YQ4 D;  4YTP C;  3AEG D;  2BS4 C;  3AE5 D;  2WDR D;  3SFE C;  1KFY D;  1KF6 C;  3P4S C;  4YSZ C;  2WDV C;  3AE7 C;  3AE8 C;  1NEN D;  3ABV D;  2H89 D;  4YSX C;  3AE8 D;  4KX6 C;  3AE6 C;  3AE3 C;  2WP9 D;  1NEK C;  3AEF C;  1YQ4 C;  3AEG C;  3AE2 D;  3AE5 C;  2WDR C;  2BS3 C;  1KFY C;  3VRB D;  1YQ3 D;  4YSY C;  3AE9 D;  5C2T D;  4YSY D;  1NEN C;  3ABV C;  2H89 C;  3VR9 D;  3CIR D;  2H88 D;  2WP9 C;  5C3J D;  3AEB D;  3VRA D;  3AEC D;  3AE2 C;  3P4R D;  3VRB C;  1YQ3 C;  2BS2 C;  2ACZ C;  2WS3 D;  1E7P C;  3P4P D;  3AE9 C;  5C2T C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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