4YT0C

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with 2-methyl-n-[3-(1-methylethoxy)phenyl]benzamide.
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
153
structure length
153
Chain Sequence
EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 53
structure length 153
sequence length 153
chains with identical sequence G
ec nomenclature
pdb deposition date 2015-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01127 Sdh_cyt Succinate dehydrogenase/Fumarate reductase transmembrane subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4yt0C00
2WQYC 1ZP0C 1NEKC 3ABVD 3AE8D 5C3JD 1KFYC 4YSXC 3P4QC 3SFDC 1ZP0D 1YQ3C 1KFYD 2WDVD 3AEDD 3P4QD 3SFDD 1YQ3D 3CIRC 2WU2D 4KX6C 4YSYD 3AE9C 4YXDC 3CIRD 2WDQC 2WU5D 3SFEC 1NENC 4YXDD 2WS3C 2FBWC 3SFED 1L0VC 2H88D 2ACZC 4YTND 3AE5C 3VRBC 3AE6C 1L0VD 2WP9C 2WQYD 1NEKD 3AE5D 3VRBD 1KF6C 3AECC 3AEEC 4YSXD 3P4RC 5C2TC 2B76C 4YT0C 3AEED 1YQ4C 2B76D 2BS4C 4YT0D 4KX6D 1ZOYC 3AE9D 2WDQD 3AEAC 3P4SC 3VR9C 1NEND 2WS3D 4YSZC 3P4SD 2FBWD 3AE1C 2ACZD 4YSZD 3AEGC 3VR8C 4YTPC 3AEFC 3AE6D 2WP9D 1QLBC 3AEBC 1KF6D 3AE4C 3VR8D 4YTPD 3AECD 3AE3C 4YTMC 2H89C 3P4RD 5C2TD 3ABVC 4YTMD 2BS2C 1YQ4D 3AE7C 3P4PC 1ZOYD 2WDVC 3AEDC 3AE7D 3AEAD 3P4PD 3VR9D 3AE2C 2WU2C 4YSYC 3AE1D 3AE2D 3VRAC 1E7PC 2WU5C 2WDRC 3AEGD 2BS3C 3AEFD 3VRAD 2WDRD 3AEBD 2H88C 3AE4D 4YTNC 3AE8C 5C3JC 3AE3D 2H89D
chains in the Genus database with same CATH superfamily
2WQYC 1ZP0C 1NEKC 3ABVD 3AE8D 5C3JD 1KFYC 2ZFYA 4YSXC 3P4QC 3SFDC 1ZP0D 1YQ3C 1KFYD 2WDVD 3AEDD 3P4QD 3SFDD 1YQ3D 3CIRC 2WU2D 4KX6C 4YSYD 3AE9C 4I6LA 4YXDC 3CIRD 2WDQC 2WU5D 3SFEC 1NENC 4YXDD 2WS3C 4FJVA 2FBWC 3SFED 1L0VC 1TFFA 2H88D 2ACZC 4YTND 3AE5C 3VRBC 3AE6C 1L0VD 2WP9C 2WQYD 1NEKD 3AE5D 3VRBD 1KF6C 3AECC 3AEEC 4YSXD 3P4RC 5C2TC 2B76C 4YT0C 4DHJA 3AEED 1YQ4C 2B76D 2BS4C 4YT0D 4KX6D 1ZOYC 3AE9D 2WDQD 3AEAC 3P4SC 3VR9C 1NEND 2WS3D 4YSZC 3P4SD 2FBWD 3AE1C 3VONA 2ACZD 4YSZD 3AEGC 3VR8C 4YTPC 3AEFC 3AE6D 2WP9D 1QLBC 3AEBC 1KF6D 3AE4C 3VR8D 4YTPD 4DDIA 4DDGA 3AECD 3AE3C 4YTMC 2H89C 3P4RD 5C2TD 3ABVC 4YTMD 2BS2C 1YQ4D 3AE7C 3P4PC 1ZOYD 2WDVC 3AEDC 3AE7D 3AEAD 3P4PD 3VR9D 3AE2C 2WU2C 4YSYC 4LDTA 3AE1D 3AE2D 3VRAC 1E7PC 2WU5C 2WDRC 3AEGD 2BS3C 3AEFD 3VRAD 2WDRD 3AEBD 4DHZA 2H88C 3AE4D 4YTNC 3AE8C 5C3JC 3AE3D 4DHIB 2H89D
chains in the Genus database with same CATH topology
2WQYC 1ZP0C 1NEKC 3ABVD 3AE8D 5C3JD 1KFYC 4YSXC 3P4QC 3SFDC 1ZP0D 1YQ3C 1KFYD 2WDVD 3AEDD 3P4QD 3SFDD 1YQ3D 3CIRC 2WU2D 4KX6C 4YSYD 3AE9C 4YXDC 3CIRD 2WDQC 2WU5D 3SFEC 1NENC 4YXDD 2WS3C 2FBWC 3SFED 1L0VC 2H88D 2ACZC 4YTND 3AE5C 3VRBC 3AE6C 1L0VD 2WP9C 2WQYD 1NEKD 3AE5D 3VRBD 1KF6C 3AECC 3AEEC 4YSXD 3P4RC 5C2TC 2B76C 4YT0C 3AEED 1YQ4C 2B76D 2BS4C 4YT0D 4KX6D 1ZOYC 3AE9D 2WDQD 3AEAC 3P4SC 3VR9C 1NEND 2WS3D 4YSZC 3P4SD 2FBWD 3AE1C 2ACZD 4YSZD 3AEGC 3VR8C 4YTPC 3AEFC 3AE6D 2WP9D 1QLBC 3AEBC 1KF6D 3AE4C 3VR8D 4YTPD 3AECD 3AE3C 4YTMC 2H89C 3P4RD 5C2TD 3ABVC 4YTMD 2BS2C 1YQ4D 3AE7C 3P4PC 1ZOYD 2WDVC 3AEDC 3AE7D 3AEAD 3P4PD 3VR9D 3AE2C 2WU2C 4YSYC 3AE1D 3AE2D 3VRAC 1E7PC 2WU5C 2WDRC 3AEGD 2BS3C 3AEFD 3VRAD 2WDRD 3AEBD 2H88C 3AE4D 4YTNC 3AE8C 5C3JC 3AE3D 2H89D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WQY C;  1ZP0 C;  1NEK C;  3ABV D;  3AE8 D;  5C3J D;  1KFY C;  4YSX C;  3P4Q C;  3SFD C;  1ZP0 D;  1YQ3 C;  1KFY D;  2WDV D;  3AED D;  3P4Q D;  3SFD D;  1YQ3 D;  3CIR C;  2WU2 D;  4KX6 C;  4YSY D;  3AE9 C;  4YXD C;  3CIR D;  2WDQ C;  2WU5 D;  3SFE C;  1NEN C;  4YXD D;  2WS3 C;  2FBW C;  3SFE D;  1L0V C;  2H88 D;  2ACZ C;  4YTN D;  3AE5 C;  3VRB C;  3AE6 C;  1L0V D;  2WP9 C;  2WQY D;  1NEK D;  3AE5 D;  3VRB D;  1KF6 C;  3AEC C;  3AEE C;  4YSX D;  3P4R C;  5C2T C;  2B76 C;  4YT0 C;  3AEE D;  1YQ4 C;  2B76 D;  2BS4 C;  4YT0 D;  4KX6 D;  1ZOY C;  3AE9 D;  2WDQ D;  3AEA C;  3P4S C;  3VR9 C;  1NEN D;  2WS3 D;  4YSZ C;  3P4S D;  2FBW D;  3AE1 C;  2ACZ D;  4YSZ D;  3AEG C;  3VR8 C;  4YTP C;  3AEF C;  3AE6 D;  2WP9 D;  1QLB C;  3AEB C;  1KF6 D;  3AE4 C;  3VR8 D;  4YTP D;  3AEC D;  3AE3 C;  4YTM C;  2H89 C;  3P4R D;  5C2T D;  3ABV C;  4YTM D;  2BS2 C;  1YQ4 D;  3AE7 C;  3P4P C;  1ZOY D;  2WDV C;  3AED C;  3AE7 D;  3AEA D;  3P4P D;  3VR9 D;  3AE2 C;  2WU2 C;  4YSY C;  3AE1 D;  3AE2 D;  3VRA C;  1E7P C;  2WU5 C;  2WDR C;  3AEG D;  2BS3 C;  3AEF D;  3VRA D;  2WDR D;  3AEB D;  2H88 C;  3AE4 D;  4YTN C;  3AE8 C;  5C3J C;  3AE3 D;  2H89 D; 
#chains in the Genus database with same CATH topology
 2WQY C;  1ZP0 C;  1NEK C;  3ABV D;  3AE8 D;  5C3J D;  1KFY C;  2ZFY A;  4YSX C;  3P4Q C;  3SFD C;  1ZP0 D;  1YQ3 C;  1KFY D;  2WDV D;  3AED D;  3P4Q D;  3SFD D;  1YQ3 D;  3CIR C;  2WU2 D;  4KX6 C;  4YSY D;  3AE9 C;  4I6L A;  4YXD C;  3CIR D;  2WDQ C;  2WU5 D;  3SFE C;  1NEN C;  4YXD D;  2WS3 C;  4FJV A;  2FBW C;  3SFE D;  1L0V C;  1TFF A;  2H88 D;  2ACZ C;  4YTN D;  3AE5 C;  3VRB C;  3AE6 C;  1L0V D;  2WP9 C;  2WQY D;  1NEK D;  3AE5 D;  3VRB D;  1KF6 C;  3AEC C;  3AEE C;  4YSX D;  3P4R C;  5C2T C;  2B76 C;  4YT0 C;  4DHJ A;  3AEE D;  1YQ4 C;  2B76 D;  2BS4 C;  4YT0 D;  4KX6 D;  1ZOY C;  3AE9 D;  2WDQ D;  3AEA C;  3P4S C;  3VR9 C;  1NEN D;  2WS3 D;  4YSZ C;  3P4S D;  2FBW D;  3AE1 C;  3VON A;  2ACZ D;  4YSZ D;  3AEG C;  3VR8 C;  4YTP C;  3AEF C;  3AE6 D;  2WP9 D;  1QLB C;  3AEB C;  1KF6 D;  3AE4 C;  3VR8 D;  4YTP D;  4DDI A;  4DDG A;  3AEC D;  3AE3 C;  4YTM C;  2H89 C;  3P4R D;  5C2T D;  3ABV C;  4YTM D;  2BS2 C;  1YQ4 D;  3AE7 C;  3P4P C;  1ZOY D;  2WDV C;  3AED C;  3AE7 D;  3AEA D;  3P4P D;  3VR9 D;  3AE2 C;  2WU2 C;  4YSY C;  4LDT A;  3AE1 D;  3AE2 D;  3VRA C;  1E7P C;  2WU5 C;  2WDR C;  3AEG D;  2BS3 C;  3AEF D;  3VRA D;  2WDR D;  3AEB D;  4DHZ A;  2H88 C;  3AE4 D;  4YTN C;  3AE8 C;  5C3J C;  3AE3 D;  4DHI B;  2H89 D; 
#chains in the Genus database with same CATH homology
 2WQY C;  1ZP0 C;  1NEK C;  3ABV D;  3AE8 D;  5C3J D;  1KFY C;  4YSX C;  3P4Q C;  3SFD C;  1ZP0 D;  1YQ3 C;  1KFY D;  2WDV D;  3AED D;  3P4Q D;  3SFD D;  1YQ3 D;  3CIR C;  2WU2 D;  4KX6 C;  4YSY D;  3AE9 C;  4YXD C;  3CIR D;  2WDQ C;  2WU5 D;  3SFE C;  1NEN C;  4YXD D;  2WS3 C;  2FBW C;  3SFE D;  1L0V C;  2H88 D;  2ACZ C;  4YTN D;  3AE5 C;  3VRB C;  3AE6 C;  1L0V D;  2WP9 C;  2WQY D;  1NEK D;  3AE5 D;  3VRB D;  1KF6 C;  3AEC C;  3AEE C;  4YSX D;  3P4R C;  5C2T C;  2B76 C;  4YT0 C;  3AEE D;  1YQ4 C;  2B76 D;  2BS4 C;  4YT0 D;  4KX6 D;  1ZOY C;  3AE9 D;  2WDQ D;  3AEA C;  3P4S C;  3VR9 C;  1NEN D;  2WS3 D;  4YSZ C;  3P4S D;  2FBW D;  3AE1 C;  2ACZ D;  4YSZ D;  3AEG C;  3VR8 C;  4YTP C;  3AEF C;  3AE6 D;  2WP9 D;  1QLB C;  3AEB C;  1KF6 D;  3AE4 C;  3VR8 D;  4YTP D;  3AEC D;  3AE3 C;  4YTM C;  2H89 C;  3P4R D;  5C2T D;  3ABV C;  4YTM D;  2BS2 C;  1YQ4 D;  3AE7 C;  3P4P C;  1ZOY D;  2WDV C;  3AED C;  3AE7 D;  3AEA D;  3P4P D;  3VR9 D;  3AE2 C;  2WU2 C;  4YSY C;  3AE1 D;  3AE2 D;  3VRA C;  1E7P C;  2WU5 C;  2WDR C;  3AEG D;  2BS3 C;  3AEF D;  3VRA D;  2WDR D;  3AEB D;  2H88 C;  3AE4 D;  4YTN C;  3AE8 C;  5C3J C;  3AE3 D;  2H89 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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