4YT0C

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with 2-methyl-n-[3-(1-methylethoxy)phenyl]benzamide.
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
153
structure length
153
Chain Sequence
EKTPIQVWGWDYLMRQRALKRPIAPHLTIYKPQMTWMVSGLHRVTGCAMAGTLLIGGVGFSVLPLDFTTFVEFIRGLGIPWVILDTFKFIIAFPIAFHTLNGIRFIGFDMAKGTDIPSIYRGAYLVLGLAALISLAVVVYPRWERHKKATLPT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 53
structure length 153
sequence length 153
chains with identical sequence G
ec nomenclature
pdb deposition date 2015-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01127 Sdh_cyt Succinate dehydrogenase/Fumarate reductase transmembrane subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4yt0C00
4KX6D 1YQ3D 2H88D 3SFDC 3AEED 3P4QD 1KFYD 1ZOYC 3P4SC 3VRBD 1KF6D 2WQYD 4YSYD 1ZP0C 4YTPC 2WDVC 2WU5D 3AE8D 1L0VC 3P4RD 2B76C 3AEBD 3CIRD 4YSZC 3AE9C 2FBWD 2WDRC 3AEDD 2WP9D 4YTMD 4YXDD 4YSXC 2BS2C 1NENC 3AEFC 3AE7C 3VRAC 2H89D 3AE6D 3SFED 3AE4C 1NEKC 2BS3C 3ABVC 3P4PD 2WS3C 3VR9D 3AE2D 3VR8D 3AE3D 1YQ4C 3AE1C 4YTNC 3AEAD 2ACZD 2WQYC 1ZP0D 4YT0D 4YTPD 4YSYC 2WDVD 2WDQC 5C3JC 1E7PC 1L0VD 3AEGD 3AE5D 5C2TD 3AEBC 2WU2D 4YSZD 3AECC 3CIRC 2FBWC 2BS4C 2WDRD 4KX6C 3SFDD 1NEND 1YQ3C 3AEFD 2H88C 3AE6C 3AEEC 3ABVD 1ZOYD 3P4QC 1KFYC 3P4SD 3VRBC 1KF6C 3P4PC 2WS3D 3VR9C 3AE2C 2WU5C 3AE8C 1YQ4D 3VR8C 3AE3C 2B76D 3P4RC 3AE1D 4YTND 1QLBC 3AEAC 2ACZC 3AE9D 2WDQD 4YT0C 5C3JD 3AEDC 2WP9C 4YSXD 3AEGC 4YXDC 4YTMC 3AE7D 3AE5C 5C2TC 3VRAD 3AECD 2H89C 2WU2C 3SFEC 3AE4D 1NEKD
chains in the Genus database with same CATH superfamily
4KX6D 1YQ3D 2H88D 2ZFYA 3SFDC 3AEED 3P4QD 1KFYD 1ZOYC 3VONA 3P4SC 3VRBD 1KF6D 2WQYD 4DDIA 4YSYD 1ZP0C 4YTPC 2WDVC 2WU5D 3AE8D 1L0VC 3P4RD 2B76C 3AEBD 3CIRD 4YSZC 3AE9C 2FBWD 2WDRC 3AEDD 2WP9D 4YTMD 4YXDD 4YSXC 2BS2C 1NENC 3AEFC 3AE7C 3VRAC 2H89D 4DDGA 3AE6D 3SFED 3AE4C 1NEKC 2BS3C 3ABVC 3P4PD 2WS3C 3VR9D 3AE2D 3VR8D 3AE3D 1YQ4C 4I6LA 3AE1C 4YTNC 3AEAD 2ACZD 2WQYC 4DHZA 1ZP0D 4YT0D 4YTPD 4YSYC 2WDVD 2WDQC 5C3JC 1E7PC 1L0VD 3AEGD 1TFFA 3AE5D 5C2TD 3AEBC 4FJVA 2WU2D 4YSZD 3AECC 3CIRC 4DHIB 2FBWC 2BS4C 2WDRD 4KX6C 3SFDD 1NEND 1YQ3C 3AEFD 2H88C 3AE6C 3AEEC 3ABVD 1ZOYD 3P4QC 1KFYC 3P4SD 3VRBC 1KF6C 3P4PC 2WS3D 3VR9C 3AE2C 2WU5C 3AE8C 1YQ4D 3VR8C 3AE3C 2B76D 3P4RC 4LDTA 3AE1D 4YTND 1QLBC 3AEAC 2ACZC 3AE9D 2WDQD 4YT0C 5C3JD 4DHJA 3AEDC 2WP9C 4YSXD 3AEGC 4YXDC 4YTMC 3AE7D 3AE5C 5C2TC 3VRAD 3AECD 2H89C 2WU2C 3SFEC 3AE4D 1NEKD
chains in the Genus database with same CATH topology
4KX6D 1YQ3D 2H88D 3SFDC 3AEED 3P4QD 1KFYD 1ZOYC 3P4SC 3VRBD 1KF6D 2WQYD 4YSYD 1ZP0C 4YTPC 2WDVC 2WU5D 3AE8D 1L0VC 3P4RD 2B76C 3AEBD 3CIRD 4YSZC 3AE9C 2FBWD 2WDRC 3AEDD 2WP9D 4YTMD 4YXDD 4YSXC 2BS2C 1NENC 3AEFC 3AE7C 3VRAC 2H89D 3AE6D 3SFED 3AE4C 1NEKC 2BS3C 3ABVC 3P4PD 2WS3C 3VR9D 3AE2D 3VR8D 3AE3D 1YQ4C 3AE1C 4YTNC 3AEAD 2ACZD 2WQYC 1ZP0D 4YT0D 4YTPD 4YSYC 2WDVD 2WDQC 5C3JC 1E7PC 1L0VD 3AEGD 3AE5D 5C2TD 3AEBC 2WU2D 4YSZD 3AECC 3CIRC 2FBWC 2BS4C 2WDRD 4KX6C 3SFDD 1NEND 1YQ3C 3AEFD 2H88C 3AE6C 3AEEC 3ABVD 1ZOYD 3P4QC 1KFYC 3P4SD 3VRBC 1KF6C 3P4PC 2WS3D 3VR9C 3AE2C 2WU5C 3AE8C 1YQ4D 3VR8C 3AE3C 2B76D 3P4RC 3AE1D 4YTND 1QLBC 3AEAC 2ACZC 3AE9D 2WDQD 4YT0C 5C3JD 3AEDC 2WP9C 4YSXD 3AEGC 4YXDC 4YTMC 3AE7D 3AE5C 5C2TC 3VRAD 3AECD 2H89C 2WU2C 3SFEC 3AE4D 1NEKD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KX6 D;  1YQ3 D;  2H88 D;  3SFD C;  3AEE D;  3P4Q D;  1KFY D;  1ZOY C;  3P4S C;  3VRB D;  1KF6 D;  2WQY D;  4YSY D;  1ZP0 C;  4YTP C;  2WDV C;  2WU5 D;  3AE8 D;  1L0V C;  3P4R D;  2B76 C;  3AEB D;  3CIR D;  4YSZ C;  3AE9 C;  2FBW D;  2WDR C;  3AED D;  2WP9 D;  4YTM D;  4YXD D;  4YSX C;  2BS2 C;  1NEN C;  3AEF C;  3AE7 C;  3VRA C;  2H89 D;  3AE6 D;  3SFE D;  3AE4 C;  1NEK C;  2BS3 C;  3ABV C;  3P4P D;  2WS3 C;  3VR9 D;  3AE2 D;  3VR8 D;  3AE3 D;  1YQ4 C;  3AE1 C;  4YTN C;  3AEA D;  2ACZ D;  2WQY C;  1ZP0 D;  4YT0 D;  4YTP D;  4YSY C;  2WDV D;  2WDQ C;  5C3J C;  1E7P C;  1L0V D;  3AEG D;  3AE5 D;  5C2T D;  3AEB C;  2WU2 D;  4YSZ D;  3AEC C;  3CIR C;  2FBW C;  2BS4 C;  2WDR D;  4KX6 C;  3SFD D;  1NEN D;  1YQ3 C;  3AEF D;  2H88 C;  3AE6 C;  3AEE C;  3ABV D;  1ZOY D;  3P4Q C;  1KFY C;  3P4S D;  3VRB C;  1KF6 C;  3P4P C;  2WS3 D;  3VR9 C;  3AE2 C;  2WU5 C;  3AE8 C;  1YQ4 D;  3VR8 C;  3AE3 C;  2B76 D;  3P4R C;  3AE1 D;  4YTN D;  1QLB C;  3AEA C;  2ACZ C;  3AE9 D;  2WDQ D;  4YT0 C;  5C3J D;  3AED C;  2WP9 C;  4YSX D;  3AEG C;  4YXD C;  4YTM C;  3AE7 D;  3AE5 C;  5C2T C;  3VRA D;  3AEC D;  2H89 C;  2WU2 C;  3SFE C;  3AE4 D;  1NEK D; 
#chains in the Genus database with same CATH topology
 4KX6 D;  1YQ3 D;  2H88 D;  2ZFY A;  3SFD C;  3AEE D;  3P4Q D;  1KFY D;  1ZOY C;  3VON A;  3P4S C;  3VRB D;  1KF6 D;  2WQY D;  4DDI A;  4YSY D;  1ZP0 C;  4YTP C;  2WDV C;  2WU5 D;  3AE8 D;  1L0V C;  3P4R D;  2B76 C;  3AEB D;  3CIR D;  4YSZ C;  3AE9 C;  2FBW D;  2WDR C;  3AED D;  2WP9 D;  4YTM D;  4YXD D;  4YSX C;  2BS2 C;  1NEN C;  3AEF C;  3AE7 C;  3VRA C;  2H89 D;  4DDG A;  3AE6 D;  3SFE D;  3AE4 C;  1NEK C;  2BS3 C;  3ABV C;  3P4P D;  2WS3 C;  3VR9 D;  3AE2 D;  3VR8 D;  3AE3 D;  1YQ4 C;  4I6L A;  3AE1 C;  4YTN C;  3AEA D;  2ACZ D;  2WQY C;  4DHZ A;  1ZP0 D;  4YT0 D;  4YTP D;  4YSY C;  2WDV D;  2WDQ C;  5C3J C;  1E7P C;  1L0V D;  3AEG D;  1TFF A;  3AE5 D;  5C2T D;  3AEB C;  4FJV A;  2WU2 D;  4YSZ D;  3AEC C;  3CIR C;  4DHI B;  2FBW C;  2BS4 C;  2WDR D;  4KX6 C;  3SFD D;  1NEN D;  1YQ3 C;  3AEF D;  2H88 C;  3AE6 C;  3AEE C;  3ABV D;  1ZOY D;  3P4Q C;  1KFY C;  3P4S D;  3VRB C;  1KF6 C;  3P4P C;  2WS3 D;  3VR9 C;  3AE2 C;  2WU5 C;  3AE8 C;  1YQ4 D;  3VR8 C;  3AE3 C;  2B76 D;  3P4R C;  4LDT A;  3AE1 D;  4YTN D;  1QLB C;  3AEA C;  2ACZ C;  3AE9 D;  2WDQ D;  4YT0 C;  5C3J D;  4DHJ A;  3AED C;  2WP9 C;  4YSX D;  3AEG C;  4YXD C;  4YTM C;  3AE7 D;  3AE5 C;  5C2T C;  3VRA D;  3AEC D;  2H89 C;  2WU2 C;  3SFE C;  3AE4 D;  1NEK D; 
#chains in the Genus database with same CATH homology
 4KX6 D;  1YQ3 D;  2H88 D;  3SFD C;  3AEE D;  3P4Q D;  1KFY D;  1ZOY C;  3P4S C;  3VRB D;  1KF6 D;  2WQY D;  4YSY D;  1ZP0 C;  4YTP C;  2WDV C;  2WU5 D;  3AE8 D;  1L0V C;  3P4R D;  2B76 C;  3AEB D;  3CIR D;  4YSZ C;  3AE9 C;  2FBW D;  2WDR C;  3AED D;  2WP9 D;  4YTM D;  4YXD D;  4YSX C;  2BS2 C;  1NEN C;  3AEF C;  3AE7 C;  3VRA C;  2H89 D;  3AE6 D;  3SFE D;  3AE4 C;  1NEK C;  2BS3 C;  3ABV C;  3P4P D;  2WS3 C;  3VR9 D;  3AE2 D;  3VR8 D;  3AE3 D;  1YQ4 C;  3AE1 C;  4YTN C;  3AEA D;  2ACZ D;  2WQY C;  1ZP0 D;  4YT0 D;  4YTP D;  4YSY C;  2WDV D;  2WDQ C;  5C3J C;  1E7P C;  1L0V D;  3AEG D;  3AE5 D;  5C2T D;  3AEB C;  2WU2 D;  4YSZ D;  3AEC C;  3CIR C;  2FBW C;  2BS4 C;  2WDR D;  4KX6 C;  3SFD D;  1NEN D;  1YQ3 C;  3AEF D;  2H88 C;  3AE6 C;  3AEE C;  3ABV D;  1ZOY D;  3P4Q C;  1KFY C;  3P4S D;  3VRB C;  1KF6 C;  3P4P C;  2WS3 D;  3VR9 C;  3AE2 C;  2WU5 C;  3AE8 C;  1YQ4 D;  3VR8 C;  3AE3 C;  2B76 D;  3P4R C;  3AE1 D;  4YTN D;  1QLB C;  3AEA C;  2ACZ C;  3AE9 D;  2WDQ D;  4YT0 C;  5C3J D;  3AED C;  2WP9 C;  4YSX D;  3AEG C;  4YXD C;  4YTM C;  3AE7 D;  3AE5 C;  5C2T C;  3VRA D;  3AEC D;  2H89 C;  2WU2 C;  3SFE C;  3AE4 D;  1NEK D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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