4YT0D

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with 2-methyl-n-[3-(1-methylethoxy)phenyl]benzamide.
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 41
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-03-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4yt0D00
2ACZD 1QLBC 2FBWC 3AE5C 3AEFC 3P4PC 3VR8D 2WDVC 2H89C 4YSZC 1YQ3C 3AE2C 3AECC 2WP9D 3P4RD 2B76C 4YSYD 5C3JD 3AEDC 4YTMD 1E7PC 4YT0C 1L0VD 3AE4C 2WDRC 4YSXC 1NEKC 3VRBC 2WQYC 4KX6D 2WU2C 3SFED 3VR9D 2BS4C 3CIRC 2H88D 3SFDD 3AEBD 2WS3C 3P4SD 1KF6D 3VR8C 4YTND 3AE8D 2WP9C 3P4RC 4YSYC 4YTMC 5C3JC 3AEED 1L0VC 2BS2C 3P4QD 3AEFD 1ZP0D 4KX6C 3AE3D 3SFEC 2H89D 4YSZD 3VR9C 3VRAD 1ZOYD 2H88C 3AEAD 3SFDC 1YQ4D 3AE9D 2ACZC 3AEDD 3P4SC 4YTPD 2BS3C 3ABVD 3AE7D 1KF6C 3VRBD 5C2TD 4YTNC 1NEND 3AEGD 2WU5D 3AE8C 4YXDD 2WDQD 3AE6D 3AEEC 3AE1D 1KFYD 2FBWD 3P4QC 3AE5D 3P4PD 2WS3D 1ZP0C 2WDVD 3AE3C 1YQ3D 3AE2D 3AECD 2B76D 3AEBC 3VRAC 1ZOYC 3AEAC 1YQ4C 3AE9C 4YT0D 3AE4D 2WDRD 4YTPC 3ABVC 3AE7C 1NEKD 4YSXD 2WQYD 5C2TC 1NENC 3AEGC 2WU5C 2WU2D 4YXDC 2WDQC 3AE6C 3CIRD 3AE1C 1KFYC
chains in the Genus database with same CATH superfamily
2ACZD 1QLBC 2FBWC 3AE5C 3AEFC 3P4PC 4FJVA 4DHZA 3VR8D 2WDVC 2ZFYA 2H89C 4YSZC 1YQ3C 4DDIA 3AE2C 3AECC 2WP9D 3P4RD 2B76C 4YSYD 5C3JD 3AEDC 4YTMD 1E7PC 4YT0C 1L0VD 3AE4C 2WDRC 4YSXC 1NEKC 3VRBC 4LDTA 2WQYC 4KX6D 4DDGA 2WU2C 3SFED 3VR9D 2BS4C 3CIRC 2H88D 3SFDD 3AEBD 2WS3C 3P4SD 1KF6D 3VR8C 4YTND 3AE8D 2WP9C 3P4RC 4YSYC 4YTMC 5C3JC 3AEED 1L0VC 2BS2C 3P4QD 3AEFD 1ZP0D 4KX6C 3AE3D 3SFEC 2H89D 4YSZD 3VR9C 3VRAD 1ZOYD 2H88C 3AEAD 4I6LA 1YQ4D 3AE9D 3SFDC 2ACZC 3AEDD 1TFFA 3P4SC 4YTPD 2BS3C 3ABVD 3AE7D 1KF6C 3VRBD 5C2TD 4YTNC 1NEND 3AEGD 2WU5D 4DHIB 3AE8C 4YXDD 2WDQD 4DHJA 3AE6D 3AEEC 3AE1D 1KFYD 2FBWD 3P4QC 3AE5D 3P4PD 2WS3D 1ZP0C 2WDVD 3AE3C 1YQ3D 3AE2D 3AECD 2B76D 3AEBC 3VRAC 1ZOYC 3AEAC 1YQ4C 3AE9C 4YT0D 3AE4D 2WDRD 4YTPC 3ABVC 3AE7C 1NEKD 4YSXD 2WQYD 3VONA 5C2TC 1NENC 3AEGC 2WU5C 2WU2D 4YXDC 2WDQC 3AE6C 3CIRD 3AE1C 1KFYC
chains in the Genus database with same CATH topology
2ACZD 1QLBC 2FBWC 3AE5C 3AEFC 3P4PC 3VR8D 2WDVC 2H89C 4YSZC 1YQ3C 3AE2C 3AECC 2WP9D 3P4RD 2B76C 4YSYD 5C3JD 3AEDC 4YTMD 1E7PC 4YT0C 1L0VD 3AE4C 2WDRC 4YSXC 1NEKC 3VRBC 2WQYC 4KX6D 2WU2C 3SFED 3VR9D 2BS4C 3CIRC 2H88D 3SFDD 3AEBD 2WS3C 3P4SD 1KF6D 3VR8C 4YTND 3AE8D 2WP9C 3P4RC 4YSYC 4YTMC 5C3JC 3AEED 1L0VC 2BS2C 3P4QD 3AEFD 1ZP0D 4KX6C 3AE3D 3SFEC 2H89D 4YSZD 3VR9C 3VRAD 1ZOYD 2H88C 3AEAD 3SFDC 1YQ4D 3AE9D 2ACZC 3AEDD 3P4SC 4YTPD 2BS3C 3ABVD 3AE7D 1KF6C 3VRBD 5C2TD 4YTNC 1NEND 3AEGD 2WU5D 3AE8C 4YXDD 2WDQD 3AE6D 3AEEC 3AE1D 1KFYD 2FBWD 3P4QC 3AE5D 3P4PD 2WS3D 1ZP0C 2WDVD 3AE3C 1YQ3D 3AE2D 3AECD 2B76D 3AEBC 3VRAC 1ZOYC 3AEAC 1YQ4C 3AE9C 4YT0D 3AE4D 2WDRD 4YTPC 3ABVC 3AE7C 1NEKD 4YSXD 2WQYD 5C2TC 1NENC 3AEGC 2WU5C 2WU2D 4YXDC 2WDQC 3AE6C 3CIRD 3AE1C 1KFYC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ACZ D;  1QLB C;  2FBW C;  3AE5 C;  3AEF C;  3P4P C;  3VR8 D;  2WDV C;  2H89 C;  4YSZ C;  1YQ3 C;  3AE2 C;  3AEC C;  2WP9 D;  3P4R D;  2B76 C;  4YSY D;  5C3J D;  3AED C;  4YTM D;  1E7P C;  4YT0 C;  1L0V D;  3AE4 C;  2WDR C;  4YSX C;  1NEK C;  3VRB C;  2WQY C;  4KX6 D;  2WU2 C;  3SFE D;  3VR9 D;  2BS4 C;  3CIR C;  2H88 D;  3SFD D;  3AEB D;  2WS3 C;  3P4S D;  1KF6 D;  3VR8 C;  4YTN D;  3AE8 D;  2WP9 C;  3P4R C;  4YSY C;  4YTM C;  5C3J C;  3AEE D;  1L0V C;  2BS2 C;  3P4Q D;  3AEF D;  1ZP0 D;  4KX6 C;  3AE3 D;  3SFE C;  2H89 D;  4YSZ D;  3VR9 C;  3VRA D;  1ZOY D;  2H88 C;  3AEA D;  3SFD C;  1YQ4 D;  3AE9 D;  2ACZ C;  3AED D;  3P4S C;  4YTP D;  2BS3 C;  3ABV D;  3AE7 D;  1KF6 C;  3VRB D;  5C2T D;  4YTN C;  1NEN D;  3AEG D;  2WU5 D;  3AE8 C;  4YXD D;  2WDQ D;  3AE6 D;  3AEE C;  3AE1 D;  1KFY D;  2FBW D;  3P4Q C;  3AE5 D;  3P4P D;  2WS3 D;  1ZP0 C;  2WDV D;  3AE3 C;  1YQ3 D;  3AE2 D;  3AEC D;  2B76 D;  3AEB C;  3VRA C;  1ZOY C;  3AEA C;  1YQ4 C;  3AE9 C;  4YT0 D;  3AE4 D;  2WDR D;  4YTP C;  3ABV C;  3AE7 C;  1NEK D;  4YSX D;  2WQY D;  5C2T C;  1NEN C;  3AEG C;  2WU5 C;  2WU2 D;  4YXD C;  2WDQ C;  3AE6 C;  3CIR D;  3AE1 C;  1KFY C; 
#chains in the Genus database with same CATH topology
 2ACZ D;  1QLB C;  2FBW C;  3AE5 C;  3AEF C;  3P4P C;  4FJV A;  4DHZ A;  3VR8 D;  2WDV C;  2ZFY A;  2H89 C;  4YSZ C;  1YQ3 C;  4DDI A;  3AE2 C;  3AEC C;  2WP9 D;  3P4R D;  2B76 C;  4YSY D;  5C3J D;  3AED C;  4YTM D;  1E7P C;  4YT0 C;  1L0V D;  3AE4 C;  2WDR C;  4YSX C;  1NEK C;  3VRB C;  4LDT A;  2WQY C;  4KX6 D;  4DDG A;  2WU2 C;  3SFE D;  3VR9 D;  2BS4 C;  3CIR C;  2H88 D;  3SFD D;  3AEB D;  2WS3 C;  3P4S D;  1KF6 D;  3VR8 C;  4YTN D;  3AE8 D;  2WP9 C;  3P4R C;  4YSY C;  4YTM C;  5C3J C;  3AEE D;  1L0V C;  2BS2 C;  3P4Q D;  3AEF D;  1ZP0 D;  4KX6 C;  3AE3 D;  3SFE C;  2H89 D;  4YSZ D;  3VR9 C;  3VRA D;  1ZOY D;  2H88 C;  3AEA D;  4I6L A;  1YQ4 D;  3AE9 D;  3SFD C;  2ACZ C;  3AED D;  1TFF A;  3P4S C;  4YTP D;  2BS3 C;  3ABV D;  3AE7 D;  1KF6 C;  3VRB D;  5C2T D;  4YTN C;  1NEN D;  3AEG D;  2WU5 D;  4DHI B;  3AE8 C;  4YXD D;  2WDQ D;  4DHJ A;  3AE6 D;  3AEE C;  3AE1 D;  1KFY D;  2FBW D;  3P4Q C;  3AE5 D;  3P4P D;  2WS3 D;  1ZP0 C;  2WDV D;  3AE3 C;  1YQ3 D;  3AE2 D;  3AEC D;  2B76 D;  3AEB C;  3VRA C;  1ZOY C;  3AEA C;  1YQ4 C;  3AE9 C;  4YT0 D;  3AE4 D;  2WDR D;  4YTP C;  3ABV C;  3AE7 C;  1NEK D;  4YSX D;  2WQY D;  3VON A;  5C2T C;  1NEN C;  3AEG C;  2WU5 C;  2WU2 D;  4YXD C;  2WDQ C;  3AE6 C;  3CIR D;  3AE1 C;  1KFY C; 
#chains in the Genus database with same CATH homology
 2ACZ D;  1QLB C;  2FBW C;  3AE5 C;  3AEF C;  3P4P C;  3VR8 D;  2WDV C;  2H89 C;  4YSZ C;  1YQ3 C;  3AE2 C;  3AEC C;  2WP9 D;  3P4R D;  2B76 C;  4YSY D;  5C3J D;  3AED C;  4YTM D;  1E7P C;  4YT0 C;  1L0V D;  3AE4 C;  2WDR C;  4YSX C;  1NEK C;  3VRB C;  2WQY C;  4KX6 D;  2WU2 C;  3SFE D;  3VR9 D;  2BS4 C;  3CIR C;  2H88 D;  3SFD D;  3AEB D;  2WS3 C;  3P4S D;  1KF6 D;  3VR8 C;  4YTN D;  3AE8 D;  2WP9 C;  3P4R C;  4YSY C;  4YTM C;  5C3J C;  3AEE D;  1L0V C;  2BS2 C;  3P4Q D;  3AEF D;  1ZP0 D;  4KX6 C;  3AE3 D;  3SFE C;  2H89 D;  4YSZ D;  3VR9 C;  3VRA D;  1ZOY D;  2H88 C;  3AEA D;  3SFD C;  1YQ4 D;  3AE9 D;  2ACZ C;  3AED D;  3P4S C;  4YTP D;  2BS3 C;  3ABV D;  3AE7 D;  1KF6 C;  3VRB D;  5C2T D;  4YTN C;  1NEN D;  3AEG D;  2WU5 D;  3AE8 C;  4YXD D;  2WDQ D;  3AE6 D;  3AEE C;  3AE1 D;  1KFY D;  2FBW D;  3P4Q C;  3AE5 D;  3P4P D;  2WS3 D;  1ZP0 C;  2WDV D;  3AE3 C;  1YQ3 D;  3AE2 D;  3AEC D;  2B76 D;  3AEB C;  3VRA C;  1ZOY C;  3AEA C;  1YQ4 C;  3AE9 C;  4YT0 D;  3AE4 D;  2WDR D;  4YTP C;  3ABV C;  3AE7 C;  1NEK D;  4YSX D;  2WQY D;  5C2T C;  1NEN C;  3AEG C;  2WU5 C;  2WU2 D;  4YXD C;  2WDQ C;  3AE6 C;  3CIR D;  3AE1 C;  1KFY C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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