4YTMD

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with n-biphenyl-3-yl-2-(trifluoromethyl)benzamide
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/oxidoreductase inhibitor
publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule keywords Succinate dehydrogenase flavoprotein
total genus 37
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4ytmD00
3AE7D 1ZP0D 3AE7C 2BS3C 1ZP0C 3VRAD 3VRAC 3P4PD 1NEND 3ABVD 3AE3D 3AEGD 4YTMD 5C2TD 2WQYD 4YTMC 2WS3D 5C2TC 2WQYC 2WS3C 1KF6C 4YSXC 3AEBC 2BS4C 3AE9D 3AEDD 2B76D 4YTND 3AEDC 2B76C 3AEED 3AEEC 1E7PC 3AE1D 4YT0C 3VR8D 3VR8C 2H89D 2H89C 3ABVC 1L0VD 3AE6C 1L0VC 3SFED 3SFEC 1KF6D 3P4RD 3AE4D 4YSXD 3AEBD 4YSYC 3P4RC 3AE4C 2H88D 1YQ3D 2H88C 1YQ3C 3P4QD 1NEKD 3P4QC 1NEKC 1YQ4D 2WU5D 1YQ4C 2WU5C 4YT0D 3AEFD 2WDVC 2WDRD 3AEFC 2FBWD 2WDRC 2FBWC 3AE6D 4YSYD 4YTPD 3VRBD 4YTPC 3VRBC 1KFYD 1KFYC 2BS2C 3AE2D 3AE2C 2ACZD 3AECD 3CIRD 2ACZC 3AECC 3CIRC 2WU2D 2WP9D 1ZOYD 2WU2C 2WP9C 3SFDD 1ZOYC 3AEAD 2WDVD 3AE8D 3SFDC 3AE8C 3AEAC 3P4PC 1NENC 3VR9D 4KX6D 3VR9C 3AE3C 3AEGC 4KX6C 5C3JD 5C3JC 2WDQD 3P4SD 2WDQC 3P4SC 4YSZD 3AE9C 4YSZC 3AE5D 4YTNC 4YXDD 3AE5C 4YXDC 3AE1C 1QLBC
chains in the Genus database with same CATH superfamily
3AE7D 1ZP0D 3AE7C 2BS3C 1ZP0C 3VRAD 3VRAC 3P4PD 1NEND 3ABVD 3AE3D 3AEGD 4YTMD 5C2TD 2WQYD 4YTMC 2WS3D 5C2TC 2WQYC 2WS3C 1KF6C 4YSXC 3AEBC 2BS4C 2ZFYA 3AE9D 4I6LA 3AEDD 2B76D 4YTND 3AEDC 2B76C 3AEED 3AEEC 1E7PC 3AE1D 4YT0C 3VR8D 3VR8C 2H89D 4LDTA 2H89C 3ABVC 1L0VD 3AE6C 1L0VC 3SFED 3SFEC 1KF6D 4DDIA 3P4RD 3AE4D 4YSXD 3AEBD 4YSYC 3P4RC 3AE4C 4DHIB 2H88D 1YQ3D 2H88C 1YQ3C 3P4QD 1NEKD 4DHZA 3P4QC 1NEKC 1YQ4D 2WU5D 1YQ4C 2WU5C 4YT0D 3AEFD 2WDVC 2WDRD 3AEFC 2FBWD 2WDRC 2FBWC 4FJVA 3VONA 4DHJA 3AE6D 4YSYD 4YTPD 3VRBD 4YTPC 3VRBC 1KFYD 1KFYC 2BS2C 3AE2D 3AE2C 2ACZD 3AECD 3CIRD 2ACZC 3AECC 3CIRC 2WU2D 2WP9D 1ZOYD 2WU2C 2WP9C 3SFDD 4DDGA 1ZOYC 3AEAD 2WDVD 3AE8D 3SFDC 3AE8C 3AEAC 3P4PC 1NENC 3VR9D 4KX6D 3VR9C 3AE3C 3AEGC 4KX6C 5C3JD 5C3JC 2WDQD 4YXDC 3P4SD 2WDQC 3P4SC 4YSZD 3AE9C 4YSZC 3AE5D 4YTNC 4YXDD 3AE5C 1TFFA 3AE1C 1QLBC
chains in the Genus database with same CATH topology
3AE7D 1ZP0D 3AE7C 2BS3C 1ZP0C 3VRAD 3VRAC 3P4PD 1NEND 3ABVD 3AE3D 3AEGD 4YTMD 5C2TD 2WQYD 4YTMC 2WS3D 5C2TC 2WQYC 2WS3C 1KF6C 4YSXC 3AEBC 2BS4C 3AE9D 3AEDD 2B76D 4YTND 3AEDC 2B76C 3AEED 3AEEC 1E7PC 3AE1D 4YT0C 3VR8D 3VR8C 2H89D 2H89C 3ABVC 1L0VD 3AE6C 1L0VC 3SFED 3SFEC 1KF6D 3P4RD 3AE4D 4YSXD 3AEBD 4YSYC 3P4RC 3AE4C 2H88D 1YQ3D 2H88C 1YQ3C 3P4QD 1NEKD 3P4QC 1NEKC 1YQ4D 2WU5D 1YQ4C 2WU5C 4YT0D 3AEFD 2WDVC 2WDRD 3AEFC 2FBWD 2WDRC 2FBWC 3AE6D 4YSYD 4YTPD 3VRBD 4YTPC 3VRBC 1KFYD 1KFYC 2BS2C 3AE2D 3AE2C 2ACZD 3AECD 3CIRD 2ACZC 3AECC 3CIRC 2WU2D 2WP9D 1ZOYD 2WU2C 2WP9C 3SFDD 1ZOYC 3AEAD 2WDVD 3AE8D 3SFDC 3AE8C 3AEAC 3P4PC 1NENC 3VR9D 4KX6D 3VR9C 3AE3C 3AEGC 4KX6C 5C3JD 5C3JC 2WDQD 3P4SD 2WDQC 3P4SC 4YSZD 3AE9C 4YSZC 3AE5D 4YTNC 4YXDD 3AE5C 4YXDC 3AE1C 1QLBC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AE7 D;  1ZP0 D;  3AE7 C;  2BS3 C;  1ZP0 C;  3VRA D;  3VRA C;  3P4P D;  1NEN D;  3ABV D;  3AE3 D;  3AEG D;  4YTM D;  5C2T D;  2WQY D;  4YTM C;  2WS3 D;  5C2T C;  2WQY C;  2WS3 C;  1KF6 C;  4YSX C;  3AEB C;  2BS4 C;  3AE9 D;  3AED D;  2B76 D;  4YTN D;  3AED C;  2B76 C;  3AEE D;  3AEE C;  1E7P C;  3AE1 D;  4YT0 C;  3VR8 D;  3VR8 C;  2H89 D;  2H89 C;  3ABV C;  1L0V D;  3AE6 C;  1L0V C;  3SFE D;  3SFE C;  1KF6 D;  3P4R D;  3AE4 D;  4YSX D;  3AEB D;  4YSY C;  3P4R C;  3AE4 C;  2H88 D;  1YQ3 D;  2H88 C;  1YQ3 C;  3P4Q D;  1NEK D;  3P4Q C;  1NEK C;  1YQ4 D;  2WU5 D;  1YQ4 C;  2WU5 C;  4YT0 D;  3AEF D;  2WDV C;  2WDR D;  3AEF C;  2FBW D;  2WDR C;  2FBW C;  3AE6 D;  4YSY D;  4YTP D;  3VRB D;  4YTP C;  3VRB C;  1KFY D;  1KFY C;  2BS2 C;  3AE2 D;  3AE2 C;  2ACZ D;  3AEC D;  3CIR D;  2ACZ C;  3AEC C;  3CIR C;  2WU2 D;  2WP9 D;  1ZOY D;  2WU2 C;  2WP9 C;  3SFD D;  1ZOY C;  3AEA D;  2WDV D;  3AE8 D;  3SFD C;  3AE8 C;  3AEA C;  3P4P C;  1NEN C;  3VR9 D;  4KX6 D;  3VR9 C;  3AE3 C;  3AEG C;  4KX6 C;  5C3J D;  5C3J C;  2WDQ D;  3P4S D;  2WDQ C;  3P4S C;  4YSZ D;  3AE9 C;  4YSZ C;  3AE5 D;  4YTN C;  4YXD D;  3AE5 C;  4YXD C;  3AE1 C;  1QLB C; 
#chains in the Genus database with same CATH topology
 3AE7 D;  1ZP0 D;  3AE7 C;  2BS3 C;  1ZP0 C;  3VRA D;  3VRA C;  3P4P D;  1NEN D;  3ABV D;  3AE3 D;  3AEG D;  4YTM D;  5C2T D;  2WQY D;  4YTM C;  2WS3 D;  5C2T C;  2WQY C;  2WS3 C;  1KF6 C;  4YSX C;  3AEB C;  2BS4 C;  2ZFY A;  3AE9 D;  4I6L A;  3AED D;  2B76 D;  4YTN D;  3AED C;  2B76 C;  3AEE D;  3AEE C;  1E7P C;  3AE1 D;  4YT0 C;  3VR8 D;  3VR8 C;  2H89 D;  4LDT A;  2H89 C;  3ABV C;  1L0V D;  3AE6 C;  1L0V C;  3SFE D;  3SFE C;  1KF6 D;  4DDI A;  3P4R D;  3AE4 D;  4YSX D;  3AEB D;  4YSY C;  3P4R C;  3AE4 C;  4DHI B;  2H88 D;  1YQ3 D;  2H88 C;  1YQ3 C;  3P4Q D;  1NEK D;  4DHZ A;  3P4Q C;  1NEK C;  1YQ4 D;  2WU5 D;  1YQ4 C;  2WU5 C;  4YT0 D;  3AEF D;  2WDV C;  2WDR D;  3AEF C;  2FBW D;  2WDR C;  2FBW C;  4FJV A;  3VON A;  4DHJ A;  3AE6 D;  4YSY D;  4YTP D;  3VRB D;  4YTP C;  3VRB C;  1KFY D;  1KFY C;  2BS2 C;  3AE2 D;  3AE2 C;  2ACZ D;  3AEC D;  3CIR D;  2ACZ C;  3AEC C;  3CIR C;  2WU2 D;  2WP9 D;  1ZOY D;  2WU2 C;  2WP9 C;  3SFD D;  4DDG A;  1ZOY C;  3AEA D;  2WDV D;  3AE8 D;  3SFD C;  3AE8 C;  3AEA C;  3P4P C;  1NEN C;  3VR9 D;  4KX6 D;  3VR9 C;  3AE3 C;  3AEG C;  4KX6 C;  5C3J D;  5C3J C;  2WDQ D;  4YXD C;  3P4S D;  2WDQ C;  3P4S C;  4YSZ D;  3AE9 C;  4YSZ C;  3AE5 D;  4YTN C;  4YXD D;  3AE5 C;  1TFF A;  3AE1 C;  1QLB C; 
#chains in the Genus database with same CATH homology
 3AE7 D;  1ZP0 D;  3AE7 C;  2BS3 C;  1ZP0 C;  3VRA D;  3VRA C;  3P4P D;  1NEN D;  3ABV D;  3AE3 D;  3AEG D;  4YTM D;  5C2T D;  2WQY D;  4YTM C;  2WS3 D;  5C2T C;  2WQY C;  2WS3 C;  1KF6 C;  4YSX C;  3AEB C;  2BS4 C;  3AE9 D;  3AED D;  2B76 D;  4YTN D;  3AED C;  2B76 C;  3AEE D;  3AEE C;  1E7P C;  3AE1 D;  4YT0 C;  3VR8 D;  3VR8 C;  2H89 D;  2H89 C;  3ABV C;  1L0V D;  3AE6 C;  1L0V C;  3SFE D;  3SFE C;  1KF6 D;  3P4R D;  3AE4 D;  4YSX D;  3AEB D;  4YSY C;  3P4R C;  3AE4 C;  2H88 D;  1YQ3 D;  2H88 C;  1YQ3 C;  3P4Q D;  1NEK D;  3P4Q C;  1NEK C;  1YQ4 D;  2WU5 D;  1YQ4 C;  2WU5 C;  4YT0 D;  3AEF D;  2WDV C;  2WDR D;  3AEF C;  2FBW D;  2WDR C;  2FBW C;  3AE6 D;  4YSY D;  4YTP D;  3VRB D;  4YTP C;  3VRB C;  1KFY D;  1KFY C;  2BS2 C;  3AE2 D;  3AE2 C;  2ACZ D;  3AEC D;  3CIR D;  2ACZ C;  3AEC C;  3CIR C;  2WU2 D;  2WP9 D;  1ZOY D;  2WU2 C;  2WP9 C;  3SFD D;  1ZOY C;  3AEA D;  2WDV D;  3AE8 D;  3SFD C;  3AE8 C;  3AEA C;  3P4P C;  1NEN C;  3VR9 D;  4KX6 D;  3VR9 C;  3AE3 C;  3AEG C;  4KX6 C;  5C3J D;  5C3J C;  2WDQ D;  3P4S D;  2WDQ C;  3P4S C;  4YSZ D;  3AE9 C;  4YSZ C;  3AE5 D;  4YTN C;  4YXD D;  3AE5 C;  4YXD C;  3AE1 C;  1QLB C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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