4YTMD

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with n-biphenyl-3-yl-2-(trifluoromethyl)benzamide
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 37
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4ytmD00
2WP9D 2WU2C 3VR8D 3P4RC 1NEKD 5C2TC 2WDQD 4YT0D 3AE8C 4YTPC 3AE7C 3SFED 3AE5D 1E7PC 1QLBC 3VR9C 3AE2D 2WP9C 3VR8C 1NEKC 1YQ4C 2WDQC 2ACZD 4YT0C 2WU2D 4YXDD 2WU5D 3SFEC 3AE5C 2BS3C 1KFYC 5C2TD 3ABVD 3VR9D 3AEAD 2ACZC 2WQYD 4YXDC 2WU5C 2BS4C 3P4SC 1NENC 3P4QD 1YQ4D 3AE4C 3ABVC 2WDRD 1KFYD 3AE1D 3CIRD 4YSYD 3AEAC 3AECD 2WQYC 3P4QC 3P4PD 3P4SD 1NEND 1YQ3D 2WDRC 3AE3D 3AE1C 3CIRC 4YSXD 1L0VD 4YSYC 3AE4D 3AECC 3SFDD 5C3JD 4YSZD 3AEFC 3P4PC 2WDVD 1YQ3C 3AEGD 3AE3C 4YSXC 1L0VC 3AEED 3AE9D 3AE6D 2B76D 3AEBD 3SFDC 4YSZC 5C3JC 1ZP0D 1ZOYD 3AEDD 2WDVC 3AEFD 3AEGC 3AEEC 3AE9C 2WS3D 3AE6C 4YTND 3VRAD 4YTMC 2B76C 3AEBC 1ZP0C 2BS2C 1ZOYC 3AEDC 4YTNC 2WS3C 3VRAC 3VRBC 2FBWD 1KF6C 4YTMD 2H89D 2H88D 4KX6D 3P4RD 3AE8D 4YTPD 3AE2C 3AE7D 2FBWC 2H89C 2H88C 3VRBD 1KF6D 4KX6C
chains in the Genus database with same CATH superfamily
2WP9D 2WU2C 3VR8D 3P4RC 1NEKD 5C2TC 2WDQD 4YT0D 3AE8C 4YTPC 3AE7C 3SFED 3AE5D 1E7PC 1QLBC 3VR9C 3AE2D 2WP9C 3VR8C 4FJVA 1NEKC 1YQ4C 2WDQC 2ACZD 4YT0C 2WU2D 4YXDD 2WU5D 3SFEC 3AE5C 2BS3C 1KFYC 5C2TD 3ABVD 3VR9D 3AEAD 4LDTA 2ACZC 2WQYD 4YXDC 4DHJA 2WU5C 2BS4C 3P4SC 1NENC 3P4QD 4DDGA 1YQ4D 3VONA 3AE4C 3ABVC 2WDRD 1KFYD 3AE1D 3CIRD 4YSYD 3AEAC 3AECD 2WQYC 3P4QC 3P4PD 3P4SD 1NEND 1YQ3D 2WDRC 3AE3D 3AE1C 3CIRC 4YSXD 1L0VD 4YSYC 3AE4D 3AECC 4DDIA 3SFDD 5C3JD 4YSZD 3AEFC 3P4PC 2WDVD 1YQ3C 3AEGD 3AE3C 4YSXC 1L0VC 3AEED 3AE9D 2ZFYA 3AE6D 2B76D 3AEBD 3SFDC 4YSZC 5C3JC 1ZP0D 1ZOYD 3AEDD 2WDVC 3AEFD 3AEGC 3AEEC 3AE9C 2WS3D 3AE6C 4YTND 3VRAD 4YTMC 4DHZA 2B76C 3AEBC 1ZP0C 2BS2C 1ZOYC 3AEDC 1TFFA 4YTNC 2WS3C 3VRAC 3VRBC 2FBWD 1KF6C 4DHIB 4I6LA 4YTMD 2H89D 2H88D 4KX6D 3P4RD 3AE8D 4YTPD 3AE2C 3AE7D 2FBWC 2H89C 2H88C 3VRBD 1KF6D 4KX6C
chains in the Genus database with same CATH topology
2WP9D 2WU2C 3VR8D 3P4RC 1NEKD 5C2TC 2WDQD 4YT0D 3AE8C 4YTPC 3AE7C 3SFED 3AE5D 1E7PC 1QLBC 3VR9C 3AE2D 2WP9C 3VR8C 1NEKC 1YQ4C 2WDQC 2ACZD 4YT0C 2WU2D 4YXDD 2WU5D 3SFEC 3AE5C 2BS3C 1KFYC 5C2TD 3ABVD 3VR9D 3AEAD 2ACZC 2WQYD 4YXDC 2WU5C 2BS4C 3P4SC 1NENC 3P4QD 1YQ4D 3AE4C 3ABVC 2WDRD 1KFYD 3AE1D 3CIRD 4YSYD 3AEAC 3AECD 2WQYC 3P4QC 3P4PD 3P4SD 1NEND 1YQ3D 2WDRC 3AE3D 3AE1C 3CIRC 4YSXD 1L0VD 4YSYC 3AE4D 3AECC 3SFDD 5C3JD 4YSZD 3AEFC 3P4PC 2WDVD 1YQ3C 3AEGD 3AE3C 4YSXC 1L0VC 3AEED 3AE9D 3AE6D 2B76D 3AEBD 3SFDC 4YSZC 5C3JC 1ZP0D 1ZOYD 3AEDD 2WDVC 3AEFD 3AEGC 3AEEC 3AE9C 2WS3D 3AE6C 4YTND 3VRAD 4YTMC 2B76C 3AEBC 1ZP0C 2BS2C 1ZOYC 3AEDC 4YTNC 2WS3C 3VRAC 3VRBC 2FBWD 1KF6C 4YTMD 2H89D 2H88D 4KX6D 3P4RD 3AE8D 4YTPD 3AE2C 3AE7D 2FBWC 2H89C 2H88C 3VRBD 1KF6D 4KX6C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WP9 D;  2WU2 C;  3VR8 D;  3P4R C;  1NEK D;  5C2T C;  2WDQ D;  4YT0 D;  3AE8 C;  4YTP C;  3AE7 C;  3SFE D;  3AE5 D;  1E7P C;  1QLB C;  3VR9 C;  3AE2 D;  2WP9 C;  3VR8 C;  1NEK C;  1YQ4 C;  2WDQ C;  2ACZ D;  4YT0 C;  2WU2 D;  4YXD D;  2WU5 D;  3SFE C;  3AE5 C;  2BS3 C;  1KFY C;  5C2T D;  3ABV D;  3VR9 D;  3AEA D;  2ACZ C;  2WQY D;  4YXD C;  2WU5 C;  2BS4 C;  3P4S C;  1NEN C;  3P4Q D;  1YQ4 D;  3AE4 C;  3ABV C;  2WDR D;  1KFY D;  3AE1 D;  3CIR D;  4YSY D;  3AEA C;  3AEC D;  2WQY C;  3P4Q C;  3P4P D;  3P4S D;  1NEN D;  1YQ3 D;  2WDR C;  3AE3 D;  3AE1 C;  3CIR C;  4YSX D;  1L0V D;  4YSY C;  3AE4 D;  3AEC C;  3SFD D;  5C3J D;  4YSZ D;  3AEF C;  3P4P C;  2WDV D;  1YQ3 C;  3AEG D;  3AE3 C;  4YSX C;  1L0V C;  3AEE D;  3AE9 D;  3AE6 D;  2B76 D;  3AEB D;  3SFD C;  4YSZ C;  5C3J C;  1ZP0 D;  1ZOY D;  3AED D;  2WDV C;  3AEF D;  3AEG C;  3AEE C;  3AE9 C;  2WS3 D;  3AE6 C;  4YTN D;  3VRA D;  4YTM C;  2B76 C;  3AEB C;  1ZP0 C;  2BS2 C;  1ZOY C;  3AED C;  4YTN C;  2WS3 C;  3VRA C;  3VRB C;  2FBW D;  1KF6 C;  4YTM D;  2H89 D;  2H88 D;  4KX6 D;  3P4R D;  3AE8 D;  4YTP D;  3AE2 C;  3AE7 D;  2FBW C;  2H89 C;  2H88 C;  3VRB D;  1KF6 D;  4KX6 C; 
#chains in the Genus database with same CATH topology
 2WP9 D;  2WU2 C;  3VR8 D;  3P4R C;  1NEK D;  5C2T C;  2WDQ D;  4YT0 D;  3AE8 C;  4YTP C;  3AE7 C;  3SFE D;  3AE5 D;  1E7P C;  1QLB C;  3VR9 C;  3AE2 D;  2WP9 C;  3VR8 C;  4FJV A;  1NEK C;  1YQ4 C;  2WDQ C;  2ACZ D;  4YT0 C;  2WU2 D;  4YXD D;  2WU5 D;  3SFE C;  3AE5 C;  2BS3 C;  1KFY C;  5C2T D;  3ABV D;  3VR9 D;  3AEA D;  4LDT A;  2ACZ C;  2WQY D;  4YXD C;  4DHJ A;  2WU5 C;  2BS4 C;  3P4S C;  1NEN C;  3P4Q D;  4DDG A;  1YQ4 D;  3VON A;  3AE4 C;  3ABV C;  2WDR D;  1KFY D;  3AE1 D;  3CIR D;  4YSY D;  3AEA C;  3AEC D;  2WQY C;  3P4Q C;  3P4P D;  3P4S D;  1NEN D;  1YQ3 D;  2WDR C;  3AE3 D;  3AE1 C;  3CIR C;  4YSX D;  1L0V D;  4YSY C;  3AE4 D;  3AEC C;  4DDI A;  3SFD D;  5C3J D;  4YSZ D;  3AEF C;  3P4P C;  2WDV D;  1YQ3 C;  3AEG D;  3AE3 C;  4YSX C;  1L0V C;  3AEE D;  3AE9 D;  2ZFY A;  3AE6 D;  2B76 D;  3AEB D;  3SFD C;  4YSZ C;  5C3J C;  1ZP0 D;  1ZOY D;  3AED D;  2WDV C;  3AEF D;  3AEG C;  3AEE C;  3AE9 C;  2WS3 D;  3AE6 C;  4YTN D;  3VRA D;  4YTM C;  4DHZ A;  2B76 C;  3AEB C;  1ZP0 C;  2BS2 C;  1ZOY C;  3AED C;  1TFF A;  4YTN C;  2WS3 C;  3VRA C;  3VRB C;  2FBW D;  1KF6 C;  4DHI B;  4I6L A;  4YTM D;  2H89 D;  2H88 D;  4KX6 D;  3P4R D;  3AE8 D;  4YTP D;  3AE2 C;  3AE7 D;  2FBW C;  2H89 C;  2H88 C;  3VRB D;  1KF6 D;  4KX6 C; 
#chains in the Genus database with same CATH homology
 2WP9 D;  2WU2 C;  3VR8 D;  3P4R C;  1NEK D;  5C2T C;  2WDQ D;  4YT0 D;  3AE8 C;  4YTP C;  3AE7 C;  3SFE D;  3AE5 D;  1E7P C;  1QLB C;  3VR9 C;  3AE2 D;  2WP9 C;  3VR8 C;  1NEK C;  1YQ4 C;  2WDQ C;  2ACZ D;  4YT0 C;  2WU2 D;  4YXD D;  2WU5 D;  3SFE C;  3AE5 C;  2BS3 C;  1KFY C;  5C2T D;  3ABV D;  3VR9 D;  3AEA D;  2ACZ C;  2WQY D;  4YXD C;  2WU5 C;  2BS4 C;  3P4S C;  1NEN C;  3P4Q D;  1YQ4 D;  3AE4 C;  3ABV C;  2WDR D;  1KFY D;  3AE1 D;  3CIR D;  4YSY D;  3AEA C;  3AEC D;  2WQY C;  3P4Q C;  3P4P D;  3P4S D;  1NEN D;  1YQ3 D;  2WDR C;  3AE3 D;  3AE1 C;  3CIR C;  4YSX D;  1L0V D;  4YSY C;  3AE4 D;  3AEC C;  3SFD D;  5C3J D;  4YSZ D;  3AEF C;  3P4P C;  2WDV D;  1YQ3 C;  3AEG D;  3AE3 C;  4YSX C;  1L0V C;  3AEE D;  3AE9 D;  3AE6 D;  2B76 D;  3AEB D;  3SFD C;  4YSZ C;  5C3J C;  1ZP0 D;  1ZOY D;  3AED D;  2WDV C;  3AEF D;  3AEG C;  3AEE C;  3AE9 C;  2WS3 D;  3AE6 C;  4YTN D;  3VRA D;  4YTM C;  2B76 C;  3AEB C;  1ZP0 C;  2BS2 C;  1ZOY C;  3AED C;  4YTN C;  2WS3 C;  3VRA C;  3VRB C;  2FBW D;  1KF6 C;  4YTM D;  2H89 D;  2H88 D;  4KX6 D;  3P4R D;  3AE8 D;  4YTP D;  3AE2 C;  3AE7 D;  2FBW C;  2H89 C;  2H88 C;  3VRB D;  1KF6 D;  4KX6 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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