4YTND

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with n-[3-(pentafluorophenoxy)phenyl]-2-(trifluoromethyl)benzamide
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title New Insights into the Design of Inhibitors Targeted for Parasitic Anaerobic Energy Metabolism
rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase flavoprotein
total genus 38
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4ytnD00
1ZOYC 2WQYC 3AE7D 4KX6C 3AE6D 3SFDD 3AE9D 3P4RC 3CIRC 3AE5C 2H88D 2BS2C 2WP9C 3P4PC 3AEGC 2FBWD 2WU5C 3P4QC 1NEND 3AEDD 4YTMD 2BS4C 1YQ3D 2B76C 3AEED 3SFED 4KX6D 4YTPC 1YQ4D 1KF6C 3AEBC 2ACZD 3P4RD 3CIRD 5C2TC 3AE5D 4YT0C 4YSZC 3AE8C 1KFYC 2H89C 3AE2D 3AECD 3VRAC 2WU2D 1KF6D 3AE3C 4YSXC 1QLBC 3P4SD 4YXDC 5C3JC 3AEAD 1ZP0D 2WS3C 3AE8D 1ZOYD 1L0VC 3VR8C 2WQYD 4YSXD 2FBWC 2BS3C 4YTNC 2WP9D 3ABVC 3P4PD 3AEGD 2WU5D 3AE4C 3AE1C 2WDVC 3P4QD 3VRBC 3VR9C 3AEFC 2B76D 4YTPD 3AEBD 2WDQC 5C2TD 4YT0D 4YSZD 3AE7C 2WDVD 3AE6C 3SFDC 3AE9C 1KFYD 3AEFD 4YSYC 2H89D 3VRAD 3AE3D 2WDQD 1NENC 3AEDC 4YXDD 2WDRC 4YTMC 1YQ3C 3AEEC 5C3JD 3SFEC 1E7PC 2WS3D 1YQ4C 1NEKC 2ACZC 1L0VD 3VR8D 4YSYD 4YTND 3ABVD 2WDRD 3AE2C 3AE1D 3AE4D 3AECC 3VRBD 1NEKD 2WU2C 3VR9D 3P4SC 2H88C 3AEAC 1ZP0C
chains in the Genus database with same CATH superfamily
2ZFYA 1ZOYC 2WQYC 3AE7D 4KX6C 3AE6D 3SFDD 3AE9D 3P4RC 3CIRC 3AE5C 2H88D 2BS2C 2WP9C 3P4PC 3AEGC 2FBWD 2WU5C 3P4QC 1NEND 3AEDD 4YTMD 2BS4C 1YQ3D 2B76C 3AEED 3SFED 4KX6D 4YTPC 1YQ4D 1KF6C 3AEBC 2ACZD 3P4RD 3CIRD 5C2TC 4LDTA 3AE5D 4YT0C 4YSZC 3AE8C 1KFYC 2H89C 3AE2D 4FJVA 3AECD 3VRAC 2WU2D 1KF6D 3AE3C 4YSXC 1QLBC 3P4SD 4YXDC 3VONA 3AEAD 1ZP0D 4DDIA 2WS3C 3AE8D 5C3JC 4DHIB 1ZOYD 1L0VC 3VR8C 2WQYD 4DDGA 4YSXD 2FBWC 2BS3C 4YTNC 2WP9D 3ABVC 3P4PD 3AEGD 2WU5D 3AE4C 3AE1C 2WDVC 3P4QD 3VRBC 3VR9C 3AEFC 2B76D 4YTPD 3AEBD 2WDQC 5C2TD 4I6LA 4YT0D 4YSZD 4DHZA 3AE7C 2WDVD 3AE6C 3SFDC 3AE9C 1KFYD 3AEFD 4YSYC 2H89D 3VRAD 3AE3D 2WDQD 1NENC 3AEDC 4YXDD 4DHJA 2WDRC 4YTMC 1YQ3C 3AEEC 5C3JD 3SFEC 1E7PC 2WS3D 1YQ4C 1NEKC 2ACZC 1L0VD 3VR8D 4YSYD 1TFFA 4YTND 3ABVD 2WDRD 3AE2C 3AE1D 3AE4D 3AECC 3VRBD 1NEKD 2WU2C 3VR9D 3P4SC 2H88C 3AEAC 1ZP0C
chains in the Genus database with same CATH topology
1ZOYC 2WQYC 3AE7D 4KX6C 3AE6D 3SFDD 3AE9D 3P4RC 3CIRC 3AE5C 2H88D 2BS2C 2WP9C 3P4PC 3AEGC 2FBWD 2WU5C 3P4QC 1NEND 3AEDD 4YTMD 2BS4C 1YQ3D 2B76C 3AEED 3SFED 4KX6D 4YTPC 1YQ4D 1KF6C 3AEBC 2ACZD 3P4RD 3CIRD 5C2TC 3AE5D 4YT0C 4YSZC 3AE8C 1KFYC 2H89C 3AE2D 3AECD 3VRAC 2WU2D 1KF6D 3AE3C 4YSXC 1QLBC 3P4SD 4YXDC 5C3JC 3AEAD 1ZP0D 2WS3C 3AE8D 1ZOYD 1L0VC 3VR8C 2WQYD 4YSXD 2FBWC 2BS3C 4YTNC 2WP9D 3ABVC 3P4PD 3AEGD 2WU5D 3AE4C 3AE1C 2WDVC 3P4QD 3VRBC 3VR9C 3AEFC 2B76D 4YTPD 3AEBD 2WDQC 5C2TD 4YT0D 4YSZD 3AE7C 2WDVD 3AE6C 3SFDC 3AE9C 1KFYD 3AEFD 4YSYC 2H89D 3VRAD 3AE3D 2WDQD 1NENC 3AEDC 4YXDD 2WDRC 4YTMC 1YQ3C 3AEEC 5C3JD 3SFEC 1E7PC 2WS3D 1YQ4C 1NEKC 2ACZC 1L0VD 3VR8D 4YSYD 4YTND 3ABVD 2WDRD 3AE2C 3AE1D 3AE4D 3AECC 3VRBD 1NEKD 2WU2C 3VR9D 3P4SC 2H88C 3AEAC 1ZP0C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZOY C;  2WQY C;  3AE7 D;  4KX6 C;  3AE6 D;  3SFD D;  3AE9 D;  3P4R C;  3CIR C;  3AE5 C;  2H88 D;  2BS2 C;  2WP9 C;  3P4P C;  3AEG C;  2FBW D;  2WU5 C;  3P4Q C;  1NEN D;  3AED D;  4YTM D;  2BS4 C;  1YQ3 D;  2B76 C;  3AEE D;  3SFE D;  4KX6 D;  4YTP C;  1YQ4 D;  1KF6 C;  3AEB C;  2ACZ D;  3P4R D;  3CIR D;  5C2T C;  3AE5 D;  4YT0 C;  4YSZ C;  3AE8 C;  1KFY C;  2H89 C;  3AE2 D;  3AEC D;  3VRA C;  2WU2 D;  1KF6 D;  3AE3 C;  4YSX C;  1QLB C;  3P4S D;  4YXD C;  5C3J C;  3AEA D;  1ZP0 D;  2WS3 C;  3AE8 D;  1ZOY D;  1L0V C;  3VR8 C;  2WQY D;  4YSX D;  2FBW C;  2BS3 C;  4YTN C;  2WP9 D;  3ABV C;  3P4P D;  3AEG D;  2WU5 D;  3AE4 C;  3AE1 C;  2WDV C;  3P4Q D;  3VRB C;  3VR9 C;  3AEF C;  2B76 D;  4YTP D;  3AEB D;  2WDQ C;  5C2T D;  4YT0 D;  4YSZ D;  3AE7 C;  2WDV D;  3AE6 C;  3SFD C;  3AE9 C;  1KFY D;  3AEF D;  4YSY C;  2H89 D;  3VRA D;  3AE3 D;  2WDQ D;  1NEN C;  3AED C;  4YXD D;  2WDR C;  4YTM C;  1YQ3 C;  3AEE C;  5C3J D;  3SFE C;  1E7P C;  2WS3 D;  1YQ4 C;  1NEK C;  2ACZ C;  1L0V D;  3VR8 D;  4YSY D;  4YTN D;  3ABV D;  2WDR D;  3AE2 C;  3AE1 D;  3AE4 D;  3AEC C;  3VRB D;  1NEK D;  2WU2 C;  3VR9 D;  3P4S C;  2H88 C;  3AEA C;  1ZP0 C; 
#chains in the Genus database with same CATH topology
 2ZFY A;  1ZOY C;  2WQY C;  3AE7 D;  4KX6 C;  3AE6 D;  3SFD D;  3AE9 D;  3P4R C;  3CIR C;  3AE5 C;  2H88 D;  2BS2 C;  2WP9 C;  3P4P C;  3AEG C;  2FBW D;  2WU5 C;  3P4Q C;  1NEN D;  3AED D;  4YTM D;  2BS4 C;  1YQ3 D;  2B76 C;  3AEE D;  3SFE D;  4KX6 D;  4YTP C;  1YQ4 D;  1KF6 C;  3AEB C;  2ACZ D;  3P4R D;  3CIR D;  5C2T C;  4LDT A;  3AE5 D;  4YT0 C;  4YSZ C;  3AE8 C;  1KFY C;  2H89 C;  3AE2 D;  4FJV A;  3AEC D;  3VRA C;  2WU2 D;  1KF6 D;  3AE3 C;  4YSX C;  1QLB C;  3P4S D;  4YXD C;  3VON A;  3AEA D;  1ZP0 D;  4DDI A;  2WS3 C;  3AE8 D;  5C3J C;  4DHI B;  1ZOY D;  1L0V C;  3VR8 C;  2WQY D;  4DDG A;  4YSX D;  2FBW C;  2BS3 C;  4YTN C;  2WP9 D;  3ABV C;  3P4P D;  3AEG D;  2WU5 D;  3AE4 C;  3AE1 C;  2WDV C;  3P4Q D;  3VRB C;  3VR9 C;  3AEF C;  2B76 D;  4YTP D;  3AEB D;  2WDQ C;  5C2T D;  4I6L A;  4YT0 D;  4YSZ D;  4DHZ A;  3AE7 C;  2WDV D;  3AE6 C;  3SFD C;  3AE9 C;  1KFY D;  3AEF D;  4YSY C;  2H89 D;  3VRA D;  3AE3 D;  2WDQ D;  1NEN C;  3AED C;  4YXD D;  4DHJ A;  2WDR C;  4YTM C;  1YQ3 C;  3AEE C;  5C3J D;  3SFE C;  1E7P C;  2WS3 D;  1YQ4 C;  1NEK C;  2ACZ C;  1L0V D;  3VR8 D;  4YSY D;  1TFF A;  4YTN D;  3ABV D;  2WDR D;  3AE2 C;  3AE1 D;  3AE4 D;  3AEC C;  3VRB D;  1NEK D;  2WU2 C;  3VR9 D;  3P4S C;  2H88 C;  3AEA C;  1ZP0 C; 
#chains in the Genus database with same CATH homology
 1ZOY C;  2WQY C;  3AE7 D;  4KX6 C;  3AE6 D;  3SFD D;  3AE9 D;  3P4R C;  3CIR C;  3AE5 C;  2H88 D;  2BS2 C;  2WP9 C;  3P4P C;  3AEG C;  2FBW D;  2WU5 C;  3P4Q C;  1NEN D;  3AED D;  4YTM D;  2BS4 C;  1YQ3 D;  2B76 C;  3AEE D;  3SFE D;  4KX6 D;  4YTP C;  1YQ4 D;  1KF6 C;  3AEB C;  2ACZ D;  3P4R D;  3CIR D;  5C2T C;  3AE5 D;  4YT0 C;  4YSZ C;  3AE8 C;  1KFY C;  2H89 C;  3AE2 D;  3AEC D;  3VRA C;  2WU2 D;  1KF6 D;  3AE3 C;  4YSX C;  1QLB C;  3P4S D;  4YXD C;  5C3J C;  3AEA D;  1ZP0 D;  2WS3 C;  3AE8 D;  1ZOY D;  1L0V C;  3VR8 C;  2WQY D;  4YSX D;  2FBW C;  2BS3 C;  4YTN C;  2WP9 D;  3ABV C;  3P4P D;  3AEG D;  2WU5 D;  3AE4 C;  3AE1 C;  2WDV C;  3P4Q D;  3VRB C;  3VR9 C;  3AEF C;  2B76 D;  4YTP D;  3AEB D;  2WDQ C;  5C2T D;  4YT0 D;  4YSZ D;  3AE7 C;  2WDV D;  3AE6 C;  3SFD C;  3AE9 C;  1KFY D;  3AEF D;  4YSY C;  2H89 D;  3VRA D;  3AE3 D;  2WDQ D;  1NEN C;  3AED C;  4YXD D;  2WDR C;  4YTM C;  1YQ3 C;  3AEE C;  5C3J D;  3SFE C;  1E7P C;  2WS3 D;  1YQ4 C;  1NEK C;  2ACZ C;  1L0V D;  3VR8 D;  4YSY D;  4YTN D;  3ABV D;  2WDR D;  3AE2 C;  3AE1 D;  3AE4 D;  3AEC C;  3VRB D;  1NEK D;  2WU2 C;  3VR9 D;  3P4S C;  2H88 C;  3AEA C;  1ZP0 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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