4YTPD

Crystal structure of porcine heart mitochondrial complex ii bound with n-[(4-tert-butylphenyl)methyl]-2-(trifluoromethyl)benzamide
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
102
structure length
102
Chain Sequence
SSKAASLHWTGERVVSVLLLGLLPAAYLNPCSAMDYSLAAALTLHGHWGIGQVVTDYVRGDALQKVAKAGLLALSAFTFAGLCYFNYHDVGICKAVAMLWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase [ubiquinone] flavoprotein subunit, m
total genus 42
structure length 102
sequence length 102
ec nomenclature
pdb deposition date 2015-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4ytpD00
5C2TD 1ZP0C 3VR8C 2B76C 2H88C 3AE9C 1YQ3C 2H89C 3AE5C 1YQ4C 1NEKC 3AEFD 3P4RC 3P4SC 4YTPC 2WQYC 2WDVC 5C2TC 3AE1C 3VRAD 3AE4D 3AE8D 5C3JD 3VR9C 4YT0D 2WP9D 3CIRD 3P4PC 4KX6D 2WDQD 4YSZD 1L0VD 4YTMD 3AE2D 3VRAC 3AEDD 3SFDD 4YTND 2WS3D 3AECC 2WU2D 3AE8C 4YSZC 3AE7C 5C3JC 1NEND 4YXDD 3AE6D 3SFED 2FBWD 3AEGD 1KFYD 2WP9C 2WDQC 3VRBD 1L0VC 2BS2C 1KF6D 3AEFC 4YTNC 3VR8D 3AEED 2WDRD 3P4QD 2WU2C 2ACZD 1YQ3D 1ZOYD 1QLBC 4YXDC 3AE6C 3SFEC 2FBWC 1NEKD 3P4RD 4YSXD 3AE4C 3VRBC 4YT0C 3AEAD 1KF6C 2BS4C 2WDVD 4YTPD 3AE1D 3AE3D 3CIRC 3AEEC 2WDRC 3P4QC 4KX6C 4YSYD 2ACZC 1ZOYC 3ABVD 2WU5D 4YTMC 3AE2C 3VR9D 3AEBD 1ZP0D 3AEDC 3SFDC 2B76D 2H88D 2WS3C 3AE9D 4YSXC 1NENC 3P4PD 2BS3C 3AEAC 3AE5D 2H89D 1E7PC 1YQ4D 3AEGC 1KFYC 3AE3C 3AECD 3P4SD 4YSYC 3ABVC 2WU5C 3AE7D 2WQYD 3AEBC
chains in the Genus database with same CATH superfamily
5C2TD 1ZP0C 3VR8C 2B76C 2H88C 3AE9C 4DHIB 1YQ3C 4DHZA 2H89C 3AE5C 1YQ4C 1NEKC 3AEFD 3P4RC 3P4SC 4FJVA 4YTPC 2WQYC 2WDVC 5C2TC 3AE1C 3VRAD 3AE4D 3AE8D 5C3JD 3VR9C 4YT0D 4I6LA 2WP9D 3CIRD 3P4PC 4KX6D 2WDQD 4YSZD 1L0VD 4YTMD 3AE2D 3VRAC 3AEDD 3SFDD 2ZFYA 4YTND 4LDTA 2WS3D 3AECC 2WU2D 3VONA 3AE8C 4YSZC 3AE7C 5C3JC 1NEND 4YXDD 3AE6D 3SFED 2FBWD 3AEGD 1KFYD 2WP9C 4DHJA 2WDQC 3VRBD 1L0VC 1TFFA 2BS2C 1KF6D 3AEFC 4DDGA 4YTNC 3VR8D 3AEED 2WDRD 3P4QD 2WU2C 2ACZD 1YQ3D 1ZOYD 1QLBC 4YXDC 3AE6C 3SFEC 2FBWC 1NEKD 3P4RD 4YSXD 3AE4C 3VRBC 4YT0C 3AEAD 1KF6C 2BS4C 4DDIA 2WDVD 4YTPD 3AE1D 3AE3D 3CIRC 3AEEC 2WDRC 3P4QC 4KX6C 4YSYD 2ACZC 1ZOYC 3ABVD 2WU5D 4YTMC 3AE2C 3VR9D 3AEBD 1ZP0D 3AEDC 3SFDC 2B76D 2H88D 2WS3C 3AE9D 4YSXC 1NENC 3P4PD 2BS3C 3AEAC 2H89D 3AE5D 1E7PC 1YQ4D 3AEGC 1KFYC 3AE3C 3AECD 3P4SD 4YSYC 3ABVC 2WU5C 3AE7D 2WQYD 3AEBC
chains in the Genus database with same CATH topology
5C2TD 1ZP0C 3VR8C 2B76C 2H88C 3AE9C 1YQ3C 2H89C 3AE5C 1YQ4C 1NEKC 3AEFD 3P4RC 3P4SC 4YTPC 2WQYC 2WDVC 5C2TC 3AE1C 3VRAD 3AE4D 3AE8D 5C3JD 3VR9C 4YT0D 2WP9D 3CIRD 3P4PC 4KX6D 2WDQD 4YSZD 1L0VD 4YTMD 3AE2D 3VRAC 3AEDD 3SFDD 4YTND 2WS3D 3AECC 2WU2D 3AE8C 4YSZC 3AE7C 5C3JC 1NEND 4YXDD 3AE6D 3SFED 2FBWD 3AEGD 1KFYD 2WP9C 2WDQC 3VRBD 1L0VC 2BS2C 1KF6D 3AEFC 4YTNC 3VR8D 3AEED 2WDRD 3P4QD 2WU2C 2ACZD 1YQ3D 1ZOYD 1QLBC 4YXDC 3AE6C 3SFEC 2FBWC 1NEKD 3P4RD 4YSXD 3AE4C 3VRBC 4YT0C 3AEAD 1KF6C 2BS4C 2WDVD 4YTPD 3AE1D 3AE3D 3CIRC 3AEEC 2WDRC 3P4QC 4KX6C 4YSYD 2ACZC 1ZOYC 3ABVD 2WU5D 4YTMC 3AE2C 3VR9D 3AEBD 1ZP0D 3AEDC 3SFDC 2B76D 2H88D 2WS3C 3AE9D 4YSXC 1NENC 3P4PD 2BS3C 3AEAC 3AE5D 2H89D 1E7PC 1YQ4D 3AEGC 1KFYC 3AE3C 3AECD 3P4SD 4YSYC 3ABVC 2WU5C 3AE7D 2WQYD 3AEBC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C2T D;  1ZP0 C;  3VR8 C;  2B76 C;  2H88 C;  3AE9 C;  1YQ3 C;  2H89 C;  3AE5 C;  1YQ4 C;  1NEK C;  3AEF D;  3P4R C;  3P4S C;  4YTP C;  2WQY C;  2WDV C;  5C2T C;  3AE1 C;  3VRA D;  3AE4 D;  3AE8 D;  5C3J D;  3VR9 C;  4YT0 D;  2WP9 D;  3CIR D;  3P4P C;  4KX6 D;  2WDQ D;  4YSZ D;  1L0V D;  4YTM D;  3AE2 D;  3VRA C;  3AED D;  3SFD D;  4YTN D;  2WS3 D;  3AEC C;  2WU2 D;  3AE8 C;  4YSZ C;  3AE7 C;  5C3J C;  1NEN D;  4YXD D;  3AE6 D;  3SFE D;  2FBW D;  3AEG D;  1KFY D;  2WP9 C;  2WDQ C;  3VRB D;  1L0V C;  2BS2 C;  1KF6 D;  3AEF C;  4YTN C;  3VR8 D;  3AEE D;  2WDR D;  3P4Q D;  2WU2 C;  2ACZ D;  1YQ3 D;  1ZOY D;  1QLB C;  4YXD C;  3AE6 C;  3SFE C;  2FBW C;  1NEK D;  3P4R D;  4YSX D;  3AE4 C;  3VRB C;  4YT0 C;  3AEA D;  1KF6 C;  2BS4 C;  2WDV D;  4YTP D;  3AE1 D;  3AE3 D;  3CIR C;  3AEE C;  2WDR C;  3P4Q C;  4KX6 C;  4YSY D;  2ACZ C;  1ZOY C;  3ABV D;  2WU5 D;  4YTM C;  3AE2 C;  3VR9 D;  3AEB D;  1ZP0 D;  3AED C;  3SFD C;  2B76 D;  2H88 D;  2WS3 C;  3AE9 D;  4YSX C;  1NEN C;  3P4P D;  2BS3 C;  3AEA C;  3AE5 D;  2H89 D;  1E7P C;  1YQ4 D;  3AEG C;  1KFY C;  3AE3 C;  3AEC D;  3P4S D;  4YSY C;  3ABV C;  2WU5 C;  3AE7 D;  2WQY D;  3AEB C; 
#chains in the Genus database with same CATH topology
 5C2T D;  1ZP0 C;  3VR8 C;  2B76 C;  2H88 C;  3AE9 C;  4DHI B;  1YQ3 C;  4DHZ A;  2H89 C;  3AE5 C;  1YQ4 C;  1NEK C;  3AEF D;  3P4R C;  3P4S C;  4FJV A;  4YTP C;  2WQY C;  2WDV C;  5C2T C;  3AE1 C;  3VRA D;  3AE4 D;  3AE8 D;  5C3J D;  3VR9 C;  4YT0 D;  4I6L A;  2WP9 D;  3CIR D;  3P4P C;  4KX6 D;  2WDQ D;  4YSZ D;  1L0V D;  4YTM D;  3AE2 D;  3VRA C;  3AED D;  3SFD D;  2ZFY A;  4YTN D;  4LDT A;  2WS3 D;  3AEC C;  2WU2 D;  3VON A;  3AE8 C;  4YSZ C;  3AE7 C;  5C3J C;  1NEN D;  4YXD D;  3AE6 D;  3SFE D;  2FBW D;  3AEG D;  1KFY D;  2WP9 C;  4DHJ A;  2WDQ C;  3VRB D;  1L0V C;  1TFF A;  2BS2 C;  1KF6 D;  3AEF C;  4DDG A;  4YTN C;  3VR8 D;  3AEE D;  2WDR D;  3P4Q D;  2WU2 C;  2ACZ D;  1YQ3 D;  1ZOY D;  1QLB C;  4YXD C;  3AE6 C;  3SFE C;  2FBW C;  1NEK D;  3P4R D;  4YSX D;  3AE4 C;  3VRB C;  4YT0 C;  3AEA D;  1KF6 C;  2BS4 C;  4DDI A;  2WDV D;  4YTP D;  3AE1 D;  3AE3 D;  3CIR C;  3AEE C;  2WDR C;  3P4Q C;  4KX6 C;  4YSY D;  2ACZ C;  1ZOY C;  3ABV D;  2WU5 D;  4YTM C;  3AE2 C;  3VR9 D;  3AEB D;  1ZP0 D;  3AED C;  3SFD C;  2B76 D;  2H88 D;  2WS3 C;  3AE9 D;  4YSX C;  1NEN C;  3P4P D;  2BS3 C;  3AEA C;  2H89 D;  3AE5 D;  1E7P C;  1YQ4 D;  3AEG C;  1KFY C;  3AE3 C;  3AEC D;  3P4S D;  4YSY C;  3ABV C;  2WU5 C;  3AE7 D;  2WQY D;  3AEB C; 
#chains in the Genus database with same CATH homology
 5C2T D;  1ZP0 C;  3VR8 C;  2B76 C;  2H88 C;  3AE9 C;  1YQ3 C;  2H89 C;  3AE5 C;  1YQ4 C;  1NEK C;  3AEF D;  3P4R C;  3P4S C;  4YTP C;  2WQY C;  2WDV C;  5C2T C;  3AE1 C;  3VRA D;  3AE4 D;  3AE8 D;  5C3J D;  3VR9 C;  4YT0 D;  2WP9 D;  3CIR D;  3P4P C;  4KX6 D;  2WDQ D;  4YSZ D;  1L0V D;  4YTM D;  3AE2 D;  3VRA C;  3AED D;  3SFD D;  4YTN D;  2WS3 D;  3AEC C;  2WU2 D;  3AE8 C;  4YSZ C;  3AE7 C;  5C3J C;  1NEN D;  4YXD D;  3AE6 D;  3SFE D;  2FBW D;  3AEG D;  1KFY D;  2WP9 C;  2WDQ C;  3VRB D;  1L0V C;  2BS2 C;  1KF6 D;  3AEF C;  4YTN C;  3VR8 D;  3AEE D;  2WDR D;  3P4Q D;  2WU2 C;  2ACZ D;  1YQ3 D;  1ZOY D;  1QLB C;  4YXD C;  3AE6 C;  3SFE C;  2FBW C;  1NEK D;  3P4R D;  4YSX D;  3AE4 C;  3VRB C;  4YT0 C;  3AEA D;  1KF6 C;  2BS4 C;  2WDV D;  4YTP D;  3AE1 D;  3AE3 D;  3CIR C;  3AEE C;  2WDR C;  3P4Q C;  4KX6 C;  4YSY D;  2ACZ C;  1ZOY C;  3ABV D;  2WU5 D;  4YTM C;  3AE2 C;  3VR9 D;  3AEB D;  1ZP0 D;  3AED C;  3SFD C;  2B76 D;  2H88 D;  2WS3 C;  3AE9 D;  4YSX C;  1NEN C;  3P4P D;  2BS3 C;  3AEA C;  3AE5 D;  2H89 D;  1E7P C;  1YQ4 D;  3AEG C;  1KFY C;  3AE3 C;  3AEC D;  3P4S D;  4YSY C;  3ABV C;  2WU5 C;  3AE7 D;  2WQY D;  3AEB C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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