4YXDD

Crystal structure of porcine heart mitochondrial complex ii bound with flutolanil
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
102
structure length
102
Chain Sequence
SSKAASLHWTGERVVSVLLLGLLPAAYLNPCSAMDYSLAAALTLHGHWGIGQVVTDYVRGDALQKVAKAGLLALSAFTFAGLCYFNYHDVGICKAVAMLWKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase [ubiquinone] flavoprotein subunit, m
total genus 40
structure length 102
sequence length 102
ec nomenclature
pdb deposition date 2015-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 4yxdD00
1E7PC 2BS3C 3AEAC 2WU2D 3AE5C 3AEFC 3AEBD 1ZP0C 3AE6D 1YQ3D 5C3JC 3AE7C 3AEEC 2H88C 3P4PD 4YTPC 3CIRD 4YSXC 3AE2C 2WU5C 4YT0D 2FBWD 2WP9D 3SFDD 3AE4C 2H89C 3AE9C 1ZOYD 3AECD 3AE3C 3ABVD 1KFYC 1QLBC 1NENC 3AEDD 3VRBD 3VR9D 2ACZC 3SFEC 3VR8D 1NEKD 4YSYC 4YTND 3P4SD 5C2TD 1YQ4C 4YTMC 1L0VC 3AE5D 4YSZC 3P4RC 2WDQD 3AEFD 2WDVC 3AE1D 2WDRC 5C3JD 3AEBC 2H88D 2B76D 4YTPD 1YQ3C 4YSXD 3AE2D 3AE8D 2WU5D 4KX6D 2WQYC 4YXDC 3P4QC 3CIRC 3AE4D 2H89D 3AEGD 4YT0C 2FBWC 3VRAC 3SFDC 1KF6C 1KFYD 2WS3C 3AEAD 2ACZD 2BS4C 3SFED 1ZP0D 2WU2C 3AE7D 3AEED 4YTMD 1L0VD 1NEKC 3AE6C 3P4SC 4YSZD 3P4RD 5C2TC 2WDVD 3P4PC 2WDRD 2WDQC 2BS2C 3AE9D 3AE1C 2WP9C 3AE3D 2WQYD 4YXDD 1ZOYC 3P4QD 2B76C 1NEND 3AECC 3AE8C 4KX6C 3ABVC 3VRAD 1KF6D 3AEDC 4YSYD 3VRBC 2WS3D 3VR9C 3AEGC 1YQ4D 3VR8C 4YTNC
chains in the Genus database with same CATH superfamily
4DHJA 1E7PC 2BS3C 3AEAC 2WU2D 4I6LA 3AE5C 3AEFC 3AEBD 1ZP0C 3AE6D 1YQ3D 3VONA 3AE7C 5C3JC 3AEEC 2H88C 3P4PD 4YTPC 3CIRD 4YSXC 3AE2C 2WU5C 4YT0D 2FBWD 2WP9D 3SFDD 3AE4C 2H89C 3AE9C 1ZOYD 3AECD 3AE3C 3ABVD 1KFYC 1QLBC 1NENC 3AEDD 3VRBD 3VR9D 4DHIB 2ACZC 4LDTA 3SFEC 3VR8D 1NEKD 4YSYC 4YTND 3P4SD 4DHZA 5C2TD 1YQ4C 2ZFYA 4YTMC 1L0VC 3AE5D 4YSZC 3P4RC 2WDQD 3AEFD 2WDVC 3AE1D 2WDRC 5C3JD 3AEBC 2H88D 2B76D 4YTPD 1YQ3C 4YSXD 3AE2D 3AE8D 2WU5D 4KX6D 2WQYC 4YXDC 3P4QC 3CIRC 3AE4D 2H89D 3AEGD 4YT0C 2FBWC 3VRAC 3SFDC 1KF6C 1KFYD 2WS3C 3AEAD 2ACZD 2BS4C 3SFED 1ZP0D 2WU2C 3AE7D 3AEED 4YTMD 1L0VD 1NEKC 3AE6C 3P4SC 4YSZD 1TFFA 3P4RD 5C2TC 2WDVD 3P4PC 2WDRD 2WDQC 2BS2C 3AE9D 4DDIA 3AE1C 2WP9C 3AE3D 2WQYD 4DDGA 1ZOYC 4YXDD 3P4QD 2B76C 1NEND 3AECC 3AE8C 4KX6C 3ABVC 3VRAD 1KF6D 3AEDC 4YSYD 3VRBC 2WS3D 3VR9C 3AEGC 4FJVA 1YQ4D 3VR8C 4YTNC
chains in the Genus database with same CATH topology
1E7PC 2BS3C 3AEAC 2WU2D 3AE5C 3AEFC 3AEBD 1ZP0C 3AE6D 1YQ3D 5C3JC 3AE7C 3AEEC 2H88C 3P4PD 4YTPC 3CIRD 4YSXC 3AE2C 2WU5C 4YT0D 2FBWD 2WP9D 3SFDD 3AE4C 2H89C 3AE9C 1ZOYD 3AECD 3AE3C 3ABVD 1KFYC 1QLBC 1NENC 3AEDD 3VRBD 3VR9D 2ACZC 3SFEC 3VR8D 1NEKD 4YSYC 4YTND 3P4SD 5C2TD 1YQ4C 4YTMC 1L0VC 3AE5D 4YSZC 3P4RC 2WDQD 3AEFD 2WDVC 3AE1D 2WDRC 5C3JD 3AEBC 2H88D 2B76D 4YTPD 1YQ3C 4YSXD 3AE2D 3AE8D 2WU5D 4KX6D 2WQYC 4YXDC 3P4QC 3CIRC 3AE4D 2H89D 3AEGD 4YT0C 2FBWC 3VRAC 3SFDC 1KF6C 1KFYD 2WS3C 3AEAD 2ACZD 2BS4C 3SFED 1ZP0D 2WU2C 3AE7D 3AEED 4YTMD 1L0VD 1NEKC 3AE6C 3P4SC 4YSZD 3P4RD 5C2TC 2WDVD 3P4PC 2WDRD 2WDQC 2BS2C 3AE9D 3AE1C 2WP9C 3AE3D 2WQYD 4YXDD 1ZOYC 3P4QD 2B76C 1NEND 3AECC 3AE8C 4KX6C 3ABVC 3VRAD 1KF6D 3AEDC 4YSYD 3VRBC 2WS3D 3VR9C 3AEGC 1YQ4D 3VR8C 4YTNC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E7P C;  2BS3 C;  3AEA C;  2WU2 D;  3AE5 C;  3AEF C;  3AEB D;  1ZP0 C;  3AE6 D;  1YQ3 D;  5C3J C;  3AE7 C;  3AEE C;  2H88 C;  3P4P D;  4YTP C;  3CIR D;  4YSX C;  3AE2 C;  2WU5 C;  4YT0 D;  2FBW D;  2WP9 D;  3SFD D;  3AE4 C;  2H89 C;  3AE9 C;  1ZOY D;  3AEC D;  3AE3 C;  3ABV D;  1KFY C;  1QLB C;  1NEN C;  3AED D;  3VRB D;  3VR9 D;  2ACZ C;  3SFE C;  3VR8 D;  1NEK D;  4YSY C;  4YTN D;  3P4S D;  5C2T D;  1YQ4 C;  4YTM C;  1L0V C;  3AE5 D;  4YSZ C;  3P4R C;  2WDQ D;  3AEF D;  2WDV C;  3AE1 D;  2WDR C;  5C3J D;  3AEB C;  2H88 D;  2B76 D;  4YTP D;  1YQ3 C;  4YSX D;  3AE2 D;  3AE8 D;  2WU5 D;  4KX6 D;  2WQY C;  4YXD C;  3P4Q C;  3CIR C;  3AE4 D;  2H89 D;  3AEG D;  4YT0 C;  2FBW C;  3VRA C;  3SFD C;  1KF6 C;  1KFY D;  2WS3 C;  3AEA D;  2ACZ D;  2BS4 C;  3SFE D;  1ZP0 D;  2WU2 C;  3AE7 D;  3AEE D;  4YTM D;  1L0V D;  1NEK C;  3AE6 C;  3P4S C;  4YSZ D;  3P4R D;  5C2T C;  2WDV D;  3P4P C;  2WDR D;  2WDQ C;  2BS2 C;  3AE9 D;  3AE1 C;  2WP9 C;  3AE3 D;  2WQY D;  4YXD D;  1ZOY C;  3P4Q D;  2B76 C;  1NEN D;  3AEC C;  3AE8 C;  4KX6 C;  3ABV C;  3VRA D;  1KF6 D;  3AED C;  4YSY D;  3VRB C;  2WS3 D;  3VR9 C;  3AEG C;  1YQ4 D;  3VR8 C;  4YTN C; 
#chains in the Genus database with same CATH topology
 4DHJ A;  1E7P C;  2BS3 C;  3AEA C;  2WU2 D;  4I6L A;  3AE5 C;  3AEF C;  3AEB D;  1ZP0 C;  3AE6 D;  1YQ3 D;  3VON A;  3AE7 C;  5C3J C;  3AEE C;  2H88 C;  3P4P D;  4YTP C;  3CIR D;  4YSX C;  3AE2 C;  2WU5 C;  4YT0 D;  2FBW D;  2WP9 D;  3SFD D;  3AE4 C;  2H89 C;  3AE9 C;  1ZOY D;  3AEC D;  3AE3 C;  3ABV D;  1KFY C;  1QLB C;  1NEN C;  3AED D;  3VRB D;  3VR9 D;  4DHI B;  2ACZ C;  4LDT A;  3SFE C;  3VR8 D;  1NEK D;  4YSY C;  4YTN D;  3P4S D;  4DHZ A;  5C2T D;  1YQ4 C;  2ZFY A;  4YTM C;  1L0V C;  3AE5 D;  4YSZ C;  3P4R C;  2WDQ D;  3AEF D;  2WDV C;  3AE1 D;  2WDR C;  5C3J D;  3AEB C;  2H88 D;  2B76 D;  4YTP D;  1YQ3 C;  4YSX D;  3AE2 D;  3AE8 D;  2WU5 D;  4KX6 D;  2WQY C;  4YXD C;  3P4Q C;  3CIR C;  3AE4 D;  2H89 D;  3AEG D;  4YT0 C;  2FBW C;  3VRA C;  3SFD C;  1KF6 C;  1KFY D;  2WS3 C;  3AEA D;  2ACZ D;  2BS4 C;  3SFE D;  1ZP0 D;  2WU2 C;  3AE7 D;  3AEE D;  4YTM D;  1L0V D;  1NEK C;  3AE6 C;  3P4S C;  4YSZ D;  1TFF A;  3P4R D;  5C2T C;  2WDV D;  3P4P C;  2WDR D;  2WDQ C;  2BS2 C;  3AE9 D;  4DDI A;  3AE1 C;  2WP9 C;  3AE3 D;  2WQY D;  4DDG A;  1ZOY C;  4YXD D;  3P4Q D;  2B76 C;  1NEN D;  3AEC C;  3AE8 C;  4KX6 C;  3ABV C;  3VRA D;  1KF6 D;  3AED C;  4YSY D;  3VRB C;  2WS3 D;  3VR9 C;  3AEG C;  4FJV A;  1YQ4 D;  3VR8 C;  4YTN C; 
#chains in the Genus database with same CATH homology
 1E7P C;  2BS3 C;  3AEA C;  2WU2 D;  3AE5 C;  3AEF C;  3AEB D;  1ZP0 C;  3AE6 D;  1YQ3 D;  5C3J C;  3AE7 C;  3AEE C;  2H88 C;  3P4P D;  4YTP C;  3CIR D;  4YSX C;  3AE2 C;  2WU5 C;  4YT0 D;  2FBW D;  2WP9 D;  3SFD D;  3AE4 C;  2H89 C;  3AE9 C;  1ZOY D;  3AEC D;  3AE3 C;  3ABV D;  1KFY C;  1QLB C;  1NEN C;  3AED D;  3VRB D;  3VR9 D;  2ACZ C;  3SFE C;  3VR8 D;  1NEK D;  4YSY C;  4YTN D;  3P4S D;  5C2T D;  1YQ4 C;  4YTM C;  1L0V C;  3AE5 D;  4YSZ C;  3P4R C;  2WDQ D;  3AEF D;  2WDV C;  3AE1 D;  2WDR C;  5C3J D;  3AEB C;  2H88 D;  2B76 D;  4YTP D;  1YQ3 C;  4YSX D;  3AE2 D;  3AE8 D;  2WU5 D;  4KX6 D;  2WQY C;  4YXD C;  3P4Q C;  3CIR C;  3AE4 D;  2H89 D;  3AEG D;  4YT0 C;  2FBW C;  3VRA C;  3SFD C;  1KF6 C;  1KFY D;  2WS3 C;  3AEA D;  2ACZ D;  2BS4 C;  3SFE D;  1ZP0 D;  2WU2 C;  3AE7 D;  3AEE D;  4YTM D;  1L0V D;  1NEK C;  3AE6 C;  3P4S C;  4YSZ D;  3P4R D;  5C2T C;  2WDV D;  3P4P C;  2WDR D;  2WDQ C;  2BS2 C;  3AE9 D;  3AE1 C;  2WP9 C;  3AE3 D;  2WQY D;  4YXD D;  1ZOY C;  3P4Q D;  2B76 C;  1NEN D;  3AEC C;  3AE8 C;  4KX6 C;  3ABV C;  3VRA D;  1KF6 D;  3AED C;  4YSY D;  3VRB C;  2WS3 D;  3VR9 C;  3AEG C;  1YQ4 D;  3VR8 C;  4YTN C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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