5C2TD

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with rhodoquinone-2
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase [ubiquinone] flavoprotein subunit, m
total genus 44
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 5c2tD00
3P4QC 3AEGD 3VRBD 1KFYD 3VRAD 1YQ4C 1ZP0C 4YXDD 2WDRD 3AEFC 1ZOYC 4YSZD 2B76D 4KX6D 2WQYC 3CIRC 2WDVD 1L0VD 4YTPD 5C3JD 3AEGC 3VRBC 1KFYC 3VRAC 4YXDC 2WDRC 3AE7D 1NENC 2WS3D 4YSZC 4YTND 3P4PD 2WP9D 2B76C 4KX6C 3P4SD 4YSYD 3AE5D 2WDVC 1L0VC 3AEBD 5C3JC 2BS3C 3VR9C 3AE7C 2WS3C 3P4PC 2WP9C 3AE6D 4YSXD 2FBWD 3VR8D 3P4SC 3AECD 4YSYC 1QLBC 3AEAD 3AEBC 3AE4D 5C2TD 3P4RD 4YT0D 3AE1D 3AE8D 3SFED 1NEKD 3AE6C 4YSXC 4YTPC 3AECC 3AEAC 5C2TC 3AEED 3P4RC 2H89D 4YT0C 3AE1C 4YTNC 3SFEC 3ABVD 1NEKC 3SFDD 3AE5C 2BS4C 3AE2D 3AE3D 1YQ3D 3AEEC 3AEDD 2H89C 3AE9D 2WDQD 1KF6D 3ABVC 2WU2D 4YTMD 3SFDC 2FBWC 3VR8C 1NEND 3AE2C 2ACZD 2H88D 3AE4C 2WU5D 1E7PC 3AE3C 3P4QD 1YQ3C 3AEDC 1YQ4D 1ZP0D 3AE9C 3AE8C 3VR9D 2WDQC 1KF6C 3AEFD 2WU2C 2BS2C 4YTMC 1ZOYD 2ACZC 2H88C 2WQYD 2WU5C 3CIRD
chains in the Genus database with same CATH superfamily
3P4QC 3AEGD 3VRBD 1KFYD 3VRAD 1YQ4C 1ZP0C 3VONA 4YXDD 2WDRD 3AEFC 1ZOYC 4YSZD 2B76D 4KX6D 2WQYC 3CIRC 2WDVD 1L0VD 4YTPD 4FJVA 4DHIB 5C3JD 3AEGC 3VRBC 1KFYC 3VRAC 4YXDC 2WDRC 3AE7D 1NENC 2WS3D 4YSZC 4YTND 3P4PD 2WP9D 2B76C 4KX6C 3P4SD 4YSYD 3AE5D 2WDVC 1L0VC 3AEBD 5C3JC 2BS3C 3VR9C 4DDGA 3AE7C 4I6LA 2WS3C 3P4PC 2WP9C 3AE6D 4YSXD 2FBWD 3VR8D 3P4SC 3AECD 4YSYC 1QLBC 3AEAD 3AEBC 3AE4D 4DDIA 5C2TD 3P4RD 4YT0D 3AE1D 3AE8D 3SFED 1NEKD 3AE6C 4YSXC 4YTPC 3AECC 3AEAC 5C2TC 3AEED 3P4RC 2H89D 4YT0C 3AE1C 4YTNC 3SFEC 4LDTA 3ABVD 1NEKC 3SFDD 3AE5C 2BS4C 3AE2D 4DHZA 3AE3D 4DHJA 1YQ3D 3AEEC 3AEDD 2H89C 3AE9D 2WDQD 1KF6D 3ABVC 2WU2D 4YTMD 3SFDC 2FBWC 3VR8C 1NEND 3AE2C 2ACZD 2H88D 3AE4C 2WU5D 1E7PC 2ZFYA 3AE3C 3P4QD 1YQ3C 3AEDC 1YQ4D 1ZP0D 3AE9C 3AE8C 3VR9D 2WDQC 1KF6C 3AEFD 2WU2C 2BS2C 4YTMC 1ZOYD 2ACZC 2H88C 2WQYD 1TFFA 2WU5C 3CIRD
chains in the Genus database with same CATH topology
3P4QC 3AEGD 3VRBD 1KFYD 3VRAD 1YQ4C 1ZP0C 4YXDD 2WDRD 3AEFC 1ZOYC 4YSZD 2B76D 4KX6D 2WQYC 3CIRC 2WDVD 1L0VD 4YTPD 5C3JD 3AEGC 3VRBC 1KFYC 3VRAC 4YXDC 2WDRC 3AE7D 1NENC 2WS3D 4YSZC 4YTND 3P4PD 2WP9D 2B76C 4KX6C 3P4SD 4YSYD 3AE5D 2WDVC 1L0VC 3AEBD 5C3JC 2BS3C 3VR9C 3AE7C 2WS3C 3P4PC 2WP9C 3AE6D 4YSXD 2FBWD 3VR8D 3P4SC 3AECD 4YSYC 1QLBC 3AEAD 3AEBC 3AE4D 5C2TD 3P4RD 4YT0D 3AE1D 3AE8D 3SFED 1NEKD 3AE6C 4YSXC 4YTPC 3AECC 3AEAC 5C2TC 3AEED 3P4RC 2H89D 4YT0C 3AE1C 4YTNC 3SFEC 3ABVD 1NEKC 3SFDD 3AE5C 2BS4C 3AE2D 3AE3D 1YQ3D 3AEEC 3AEDD 2H89C 3AE9D 2WDQD 1KF6D 3ABVC 2WU2D 4YTMD 3SFDC 2FBWC 3VR8C 1NEND 3AE2C 2ACZD 2H88D 3AE4C 2WU5D 1E7PC 3AE3C 3P4QD 1YQ3C 3AEDC 1YQ4D 1ZP0D 3AE9C 3AE8C 3VR9D 2WDQC 1KF6C 3AEFD 2WU2C 2BS2C 4YTMC 1ZOYD 2ACZC 2H88C 2WQYD 2WU5C 3CIRD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P4Q C;  3AEG D;  3VRB D;  1KFY D;  3VRA D;  1YQ4 C;  1ZP0 C;  4YXD D;  2WDR D;  3AEF C;  1ZOY C;  4YSZ D;  2B76 D;  4KX6 D;  2WQY C;  3CIR C;  2WDV D;  1L0V D;  4YTP D;  5C3J D;  3AEG C;  3VRB C;  1KFY C;  3VRA C;  4YXD C;  2WDR C;  3AE7 D;  1NEN C;  2WS3 D;  4YSZ C;  4YTN D;  3P4P D;  2WP9 D;  2B76 C;  4KX6 C;  3P4S D;  4YSY D;  3AE5 D;  2WDV C;  1L0V C;  3AEB D;  5C3J C;  2BS3 C;  3VR9 C;  3AE7 C;  2WS3 C;  3P4P C;  2WP9 C;  3AE6 D;  4YSX D;  2FBW D;  3VR8 D;  3P4S C;  3AEC D;  4YSY C;  1QLB C;  3AEA D;  3AEB C;  3AE4 D;  5C2T D;  3P4R D;  4YT0 D;  3AE1 D;  3AE8 D;  3SFE D;  1NEK D;  3AE6 C;  4YSX C;  4YTP C;  3AEC C;  3AEA C;  5C2T C;  3AEE D;  3P4R C;  2H89 D;  4YT0 C;  3AE1 C;  4YTN C;  3SFE C;  3ABV D;  1NEK C;  3SFD D;  3AE5 C;  2BS4 C;  3AE2 D;  3AE3 D;  1YQ3 D;  3AEE C;  3AED D;  2H89 C;  3AE9 D;  2WDQ D;  1KF6 D;  3ABV C;  2WU2 D;  4YTM D;  3SFD C;  2FBW C;  3VR8 C;  1NEN D;  3AE2 C;  2ACZ D;  2H88 D;  3AE4 C;  2WU5 D;  1E7P C;  3AE3 C;  3P4Q D;  1YQ3 C;  3AED C;  1YQ4 D;  1ZP0 D;  3AE9 C;  3AE8 C;  3VR9 D;  2WDQ C;  1KF6 C;  3AEF D;  2WU2 C;  2BS2 C;  4YTM C;  1ZOY D;  2ACZ C;  2H88 C;  2WQY D;  2WU5 C;  3CIR D; 
#chains in the Genus database with same CATH topology
 3P4Q C;  3AEG D;  3VRB D;  1KFY D;  3VRA D;  1YQ4 C;  1ZP0 C;  3VON A;  4YXD D;  2WDR D;  3AEF C;  1ZOY C;  4YSZ D;  2B76 D;  4KX6 D;  2WQY C;  3CIR C;  2WDV D;  1L0V D;  4YTP D;  4FJV A;  4DHI B;  5C3J D;  3AEG C;  3VRB C;  1KFY C;  3VRA C;  4YXD C;  2WDR C;  3AE7 D;  1NEN C;  2WS3 D;  4YSZ C;  4YTN D;  3P4P D;  2WP9 D;  2B76 C;  4KX6 C;  3P4S D;  4YSY D;  3AE5 D;  2WDV C;  1L0V C;  3AEB D;  5C3J C;  2BS3 C;  3VR9 C;  4DDG A;  3AE7 C;  4I6L A;  2WS3 C;  3P4P C;  2WP9 C;  3AE6 D;  4YSX D;  2FBW D;  3VR8 D;  3P4S C;  3AEC D;  4YSY C;  1QLB C;  3AEA D;  3AEB C;  3AE4 D;  4DDI A;  5C2T D;  3P4R D;  4YT0 D;  3AE1 D;  3AE8 D;  3SFE D;  1NEK D;  3AE6 C;  4YSX C;  4YTP C;  3AEC C;  3AEA C;  5C2T C;  3AEE D;  3P4R C;  2H89 D;  4YT0 C;  3AE1 C;  4YTN C;  3SFE C;  4LDT A;  3ABV D;  1NEK C;  3SFD D;  3AE5 C;  2BS4 C;  3AE2 D;  4DHZ A;  3AE3 D;  4DHJ A;  1YQ3 D;  3AEE C;  3AED D;  2H89 C;  3AE9 D;  2WDQ D;  1KF6 D;  3ABV C;  2WU2 D;  4YTM D;  3SFD C;  2FBW C;  3VR8 C;  1NEN D;  3AE2 C;  2ACZ D;  2H88 D;  3AE4 C;  2WU5 D;  1E7P C;  2ZFY A;  3AE3 C;  3P4Q D;  1YQ3 C;  3AED C;  1YQ4 D;  1ZP0 D;  3AE9 C;  3AE8 C;  3VR9 D;  2WDQ C;  1KF6 C;  3AEF D;  2WU2 C;  2BS2 C;  4YTM C;  1ZOY D;  2ACZ C;  2H88 C;  2WQY D;  1TFF A;  2WU5 C;  3CIR D; 
#chains in the Genus database with same CATH homology
 3P4Q C;  3AEG D;  3VRB D;  1KFY D;  3VRA D;  1YQ4 C;  1ZP0 C;  4YXD D;  2WDR D;  3AEF C;  1ZOY C;  4YSZ D;  2B76 D;  4KX6 D;  2WQY C;  3CIR C;  2WDV D;  1L0V D;  4YTP D;  5C3J D;  3AEG C;  3VRB C;  1KFY C;  3VRA C;  4YXD C;  2WDR C;  3AE7 D;  1NEN C;  2WS3 D;  4YSZ C;  4YTN D;  3P4P D;  2WP9 D;  2B76 C;  4KX6 C;  3P4S D;  4YSY D;  3AE5 D;  2WDV C;  1L0V C;  3AEB D;  5C3J C;  2BS3 C;  3VR9 C;  3AE7 C;  2WS3 C;  3P4P C;  2WP9 C;  3AE6 D;  4YSX D;  2FBW D;  3VR8 D;  3P4S C;  3AEC D;  4YSY C;  1QLB C;  3AEA D;  3AEB C;  3AE4 D;  5C2T D;  3P4R D;  4YT0 D;  3AE1 D;  3AE8 D;  3SFE D;  1NEK D;  3AE6 C;  4YSX C;  4YTP C;  3AEC C;  3AEA C;  5C2T C;  3AEE D;  3P4R C;  2H89 D;  4YT0 C;  3AE1 C;  4YTN C;  3SFE C;  3ABV D;  1NEK C;  3SFD D;  3AE5 C;  2BS4 C;  3AE2 D;  3AE3 D;  1YQ3 D;  3AEE C;  3AED D;  2H89 C;  3AE9 D;  2WDQ D;  1KF6 D;  3ABV C;  2WU2 D;  4YTM D;  3SFD C;  2FBW C;  3VR8 C;  1NEN D;  3AE2 C;  2ACZ D;  2H88 D;  3AE4 C;  2WU5 D;  1E7P C;  3AE3 C;  3P4Q D;  1YQ3 C;  3AED C;  1YQ4 D;  1ZP0 D;  3AE9 C;  3AE8 C;  3VR9 D;  2WDQ C;  1KF6 C;  3AEF D;  2WU2 C;  2BS2 C;  4YTM C;  1ZOY D;  2ACZ C;  2H88 C;  2WQY D;  2WU5 C;  3CIR D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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