5C3JD

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with ubiquinone-1
Total Genus 37
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase [ubiquinone] flavoprotein subunit, m
total genus 37
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 5c3jD00
2WU2C 2WU2D 2WDRC 2WDRD 2WDVC 3AE8C 2WDVD 3AE8D 4YT0C 2B76C 3P4RC 4YT0D 2B76D 3P4RD 3SFDD 4YSYC 4YSYD 1L0VC 3AE3C 1L0VD 5C2TC 4YSXC 4YSXD 1NENC 4KX6C 3VR8D 1NEND 4KX6D 3AE7C 2H88C 3AE7D 2H88D 1ZP0D 3AE5D 3VRBC 2FBWD 3VRBD 1NEKC 1NEKD 3AE2C 3AE2D 3AE4C 3AE4D 3SFDC 4YTNC 4YTND 3AEEC 3AEED 3AEFD 1YQ3C 4YSZD 1YQ3D 1QLBC 3VR8C 3AE9C 3VRAC 3AE9D 3VRAD 1ZP0C 3P4PC 3CIRC 3P4PD 3CIRD 3AE5C 2FBWC 4YTPD 2WP9C 2WQYD 5C3JC 2WP9D 5C3JD 2WU5C 2WU5D 3AECC 3AECD 3SFEC 3AE6C 3SFED 3AE6D 2BS4C 3AEFC 2BS3C 4YTMD 1KF6C 1KF6D 4YSZC 1KFYC 1KFYD 3AEGD 2H89C 2H89D 2BS2C 1E7PC 1ZOYC 1ZOYD 1YQ4C 4YTPC 1YQ4D 2WQYC 2WS3C 3VR9C 2WS3D 3VR9D 3AEDC 3AE3D 3AEDD 4YXDC 4YXDD 5C2TD 4YTMC 3P4QC 3AE1C 3P4QD 3AEAC 3AE1D 2ACZC 3AEAD 2ACZD 3ABVC 3AEGC 3ABVD 3AEBC 3P4SC 3AEBD 2WDQC 3P4SD 2WDQD
chains in the Genus database with same CATH superfamily
2WU2C 2WU2D 2WDRC 2WDRD 1TFFA 2WDVC 3AE8C 2WDVD 3AE8D 4YT0C 2B76C 3P4RC 4YT0D 2B76D 3P4RD 3SFDD 4YSYC 4YSYD 1L0VC 3AE3C 1L0VD 5C2TC 4YSXC 4YSXD 1NENC 4KX6C 3VR8D 1NEND 4KX6D 3AE7C 2H88C 3AE7D 2H88D 1ZP0D 3AE5D 3VRBC 2FBWD 3VRBD 1NEKC 1NEKD 3AE2C 3AE2D 3AE4C 3AE4D 3SFDC 4YTNC 4YTND 3AEEC 3AEED 3AEFD 1YQ3C 4YSZD 1YQ3D 1QLBC 3VR8C 4DDGA 3AE9C 3VRAC 3AE9D 4DHJA 3VRAD 1ZP0C 3P4PC 3CIRC 3P4PD 3CIRD 3AE5C 2FBWC 4DDIA 4YTPD 2WP9C 2WQYD 5C3JC 2WP9D 5C3JD 2WU5C 2WU5D 3AECC 3AECD 3SFEC 3AE6C 3SFED 3AE6D 4FJVA 2BS4C 3AEFC 2BS3C 4YTMD 1KF6C 1KF6D 4YSZC 1KFYC 1KFYD 3AEGD 2H89C 2H89D 2BS2C 1E7PC 4DHIB 1ZOYC 1ZOYD 1YQ4C 4YTPC 1YQ4D 2WQYC 2WS3C 3VR9C 2WS3D 3VR9D 3AEDC 3AE3D 3AEDD 4YXDC 4YXDD 5C2TD 3VONA 4DHZA 4YTMC 2ZFYA 3P4QC 3AE1C 3P4QD 3AEAC 3AE1D 2ACZC 3AEAD 4I6LA 2ACZD 3ABVC 3AEGC 3ABVD 3AEBC 3P4SC 3AEBD 2WDQC 3P4SD 2WDQD 4LDTA
chains in the Genus database with same CATH topology
2WU2C 2WU2D 2WDRC 2WDRD 2WDVC 3AE8C 2WDVD 3AE8D 4YT0C 2B76C 3P4RC 4YT0D 2B76D 3P4RD 3SFDD 4YSYC 4YSYD 1L0VC 3AE3C 1L0VD 5C2TC 4YSXC 4YSXD 1NENC 4KX6C 3VR8D 1NEND 4KX6D 3AE7C 2H88C 3AE7D 2H88D 1ZP0D 3AE5D 3VRBC 2FBWD 3VRBD 1NEKC 1NEKD 3AE2C 3AE2D 3AE4C 3AE4D 3SFDC 4YTNC 4YTND 3AEEC 3AEED 3AEFD 1YQ3C 4YSZD 1YQ3D 1QLBC 3VR8C 3AE9C 3VRAC 3AE9D 3VRAD 1ZP0C 3P4PC 3CIRC 3P4PD 3CIRD 3AE5C 2FBWC 4YTPD 2WP9C 2WQYD 5C3JC 2WP9D 5C3JD 2WU5C 2WU5D 3AECC 3AECD 3SFEC 3AE6C 3SFED 3AE6D 2BS4C 3AEFC 2BS3C 4YTMD 1KF6C 1KF6D 4YSZC 1KFYC 1KFYD 3AEGD 2H89C 2H89D 2BS2C 1E7PC 1ZOYC 1ZOYD 1YQ4C 4YTPC 1YQ4D 2WQYC 2WS3C 3VR9C 2WS3D 3VR9D 3AEDC 3AE3D 3AEDD 4YXDC 4YXDD 5C2TD 4YTMC 3P4QC 3AE1C 3P4QD 3AEAC 3AE1D 2ACZC 3AEAD 2ACZD 3ABVC 3AEGC 3ABVD 3AEBC 3P4SC 3AEBD 2WDQC 3P4SD 2WDQD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WU2 C;  2WU2 D;  2WDR C;  2WDR D;  2WDV C;  3AE8 C;  2WDV D;  3AE8 D;  4YT0 C;  2B76 C;  3P4R C;  4YT0 D;  2B76 D;  3P4R D;  3SFD D;  4YSY C;  4YSY D;  1L0V C;  3AE3 C;  1L0V D;  5C2T C;  4YSX C;  4YSX D;  1NEN C;  4KX6 C;  3VR8 D;  1NEN D;  4KX6 D;  3AE7 C;  2H88 C;  3AE7 D;  2H88 D;  1ZP0 D;  3AE5 D;  3VRB C;  2FBW D;  3VRB D;  1NEK C;  1NEK D;  3AE2 C;  3AE2 D;  3AE4 C;  3AE4 D;  3SFD C;  4YTN C;  4YTN D;  3AEE C;  3AEE D;  3AEF D;  1YQ3 C;  4YSZ D;  1YQ3 D;  1QLB C;  3VR8 C;  3AE9 C;  3VRA C;  3AE9 D;  3VRA D;  1ZP0 C;  3P4P C;  3CIR C;  3P4P D;  3CIR D;  3AE5 C;  2FBW C;  4YTP D;  2WP9 C;  2WQY D;  5C3J C;  2WP9 D;  5C3J D;  2WU5 C;  2WU5 D;  3AEC C;  3AEC D;  3SFE C;  3AE6 C;  3SFE D;  3AE6 D;  2BS4 C;  3AEF C;  2BS3 C;  4YTM D;  1KF6 C;  1KF6 D;  4YSZ C;  1KFY C;  1KFY D;  3AEG D;  2H89 C;  2H89 D;  2BS2 C;  1E7P C;  1ZOY C;  1ZOY D;  1YQ4 C;  4YTP C;  1YQ4 D;  2WQY C;  2WS3 C;  3VR9 C;  2WS3 D;  3VR9 D;  3AED C;  3AE3 D;  3AED D;  4YXD C;  4YXD D;  5C2T D;  4YTM C;  3P4Q C;  3AE1 C;  3P4Q D;  3AEA C;  3AE1 D;  2ACZ C;  3AEA D;  2ACZ D;  3ABV C;  3AEG C;  3ABV D;  3AEB C;  3P4S C;  3AEB D;  2WDQ C;  3P4S D;  2WDQ D; 
#chains in the Genus database with same CATH topology
 2WU2 C;  2WU2 D;  2WDR C;  2WDR D;  1TFF A;  2WDV C;  3AE8 C;  2WDV D;  3AE8 D;  4YT0 C;  2B76 C;  3P4R C;  4YT0 D;  2B76 D;  3P4R D;  3SFD D;  4YSY C;  4YSY D;  1L0V C;  3AE3 C;  1L0V D;  5C2T C;  4YSX C;  4YSX D;  1NEN C;  4KX6 C;  3VR8 D;  1NEN D;  4KX6 D;  3AE7 C;  2H88 C;  3AE7 D;  2H88 D;  1ZP0 D;  3AE5 D;  3VRB C;  2FBW D;  3VRB D;  1NEK C;  1NEK D;  3AE2 C;  3AE2 D;  3AE4 C;  3AE4 D;  3SFD C;  4YTN C;  4YTN D;  3AEE C;  3AEE D;  3AEF D;  1YQ3 C;  4YSZ D;  1YQ3 D;  1QLB C;  3VR8 C;  4DDG A;  3AE9 C;  3VRA C;  3AE9 D;  4DHJ A;  3VRA D;  1ZP0 C;  3P4P C;  3CIR C;  3P4P D;  3CIR D;  3AE5 C;  2FBW C;  4DDI A;  4YTP D;  2WP9 C;  2WQY D;  5C3J C;  2WP9 D;  5C3J D;  2WU5 C;  2WU5 D;  3AEC C;  3AEC D;  3SFE C;  3AE6 C;  3SFE D;  3AE6 D;  4FJV A;  2BS4 C;  3AEF C;  2BS3 C;  4YTM D;  1KF6 C;  1KF6 D;  4YSZ C;  1KFY C;  1KFY D;  3AEG D;  2H89 C;  2H89 D;  2BS2 C;  1E7P C;  4DHI B;  1ZOY C;  1ZOY D;  1YQ4 C;  4YTP C;  1YQ4 D;  2WQY C;  2WS3 C;  3VR9 C;  2WS3 D;  3VR9 D;  3AED C;  3AE3 D;  3AED D;  4YXD C;  4YXD D;  5C2T D;  3VON A;  4DHZ A;  4YTM C;  2ZFY A;  3P4Q C;  3AE1 C;  3P4Q D;  3AEA C;  3AE1 D;  2ACZ C;  3AEA D;  4I6L A;  2ACZ D;  3ABV C;  3AEG C;  3ABV D;  3AEB C;  3P4S C;  3AEB D;  2WDQ C;  3P4S D;  2WDQ D;  4LDT A; 
#chains in the Genus database with same CATH homology
 2WU2 C;  2WU2 D;  2WDR C;  2WDR D;  2WDV C;  3AE8 C;  2WDV D;  3AE8 D;  4YT0 C;  2B76 C;  3P4R C;  4YT0 D;  2B76 D;  3P4R D;  3SFD D;  4YSY C;  4YSY D;  1L0V C;  3AE3 C;  1L0V D;  5C2T C;  4YSX C;  4YSX D;  1NEN C;  4KX6 C;  3VR8 D;  1NEN D;  4KX6 D;  3AE7 C;  2H88 C;  3AE7 D;  2H88 D;  1ZP0 D;  3AE5 D;  3VRB C;  2FBW D;  3VRB D;  1NEK C;  1NEK D;  3AE2 C;  3AE2 D;  3AE4 C;  3AE4 D;  3SFD C;  4YTN C;  4YTN D;  3AEE C;  3AEE D;  3AEF D;  1YQ3 C;  4YSZ D;  1YQ3 D;  1QLB C;  3VR8 C;  3AE9 C;  3VRA C;  3AE9 D;  3VRA D;  1ZP0 C;  3P4P C;  3CIR C;  3P4P D;  3CIR D;  3AE5 C;  2FBW C;  4YTP D;  2WP9 C;  2WQY D;  5C3J C;  2WP9 D;  5C3J D;  2WU5 C;  2WU5 D;  3AEC C;  3AEC D;  3SFE C;  3AE6 C;  3SFE D;  3AE6 D;  2BS4 C;  3AEF C;  2BS3 C;  4YTM D;  1KF6 C;  1KF6 D;  4YSZ C;  1KFY C;  1KFY D;  3AEG D;  2H89 C;  2H89 D;  2BS2 C;  1E7P C;  1ZOY C;  1ZOY D;  1YQ4 C;  4YTP C;  1YQ4 D;  2WQY C;  2WS3 C;  3VR9 C;  2WS3 D;  3VR9 D;  3AED C;  3AE3 D;  3AED D;  4YXD C;  4YXD D;  5C2T D;  4YTM C;  3P4Q C;  3AE1 C;  3P4Q D;  3AEA C;  3AE1 D;  2ACZ C;  3AEA D;  2ACZ D;  3ABV C;  3AEG C;  3ABV D;  3AEB C;  3P4S C;  3AEB D;  2WDQ C;  3P4S D;  2WDQ D; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...