1SJ8A

Crystal structure of talin residues 482-789
Total Genus 119
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
297
structure length
297
Chain Sequence
PPLTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQIGESDTDPHFQDVLMQLANAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
pubmed doi rcsb
molecule tags Structural protein
source organism Mus musculus
molecule keywords Talin 1
total genus 119
structure length 297
sequence length 297
ec nomenclature
pdb deposition date 2004-03-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09141 Talin_middle Talin, middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 1sj8A01
1.20.1440.10 Mainly Alpha Up-down Bundle de novo design (two linked rop proteins) de novo design (two linked rop proteins) 1sj8A02
1SJ8A 2L7NA 4F7GB 1YO7A 5FZTA 2L10A 4W8PA 2KBBA 3AY5A 2X0CA 3FYQA 2KGXA 3DYJA 2KVPA 1SJ7A
chains in the Genus database with same CATH superfamily
3DO9A 3KP9A 4ONRA 3WSCA 2L10A 3PHF1 3V5SA 4PL4A 2ZW3A 3AJFA 2XQYA 2JAEA 2FU2A 5JDFA 5JDLA 5HXSA 5JDQA 2A2DA 5JDHA 3AY5A 3B55A 2KGXA 2MJFB 1SJ7A 2V6EA 4HFVA 4PL5A 4Z7GA 1JQOA 5HXEA 4NV2A 4W8PA 2QSBA 2XTQA 3LJ2A 2RIOA 2RADA 3VJZA 2FEFA 3IAS1 2GSCA 2KVPA 5T1DA 4G76A 4AS2A 3SDJA 1TDPA 3I9V1 2V1CC 4JCVE 4NV5A 2LQUA 3FBVA 5JDNA 4GXTA 4F7GB 4AS3A 3M1CA 5JDMA 2HGKA 2F6MB 4U6RA 5HGIA 2L7NA 4O1OA 4OAVB 5HWYA 2JB1A 4YZDA 4Z7HA 2KKMA 2A2CA 5HXCA 2L1LB 3P23A 2XMXA 3FVVA 1U5KA 3L0IA 4O1PA 2YFBA 3JSBA 2FUG1 4I1TA 5HXRA 5HYAA 4PL3A 2BL7A 2E8GA 3UITA 2IP6A 2X0CA 2CAZB 2MTCA 3VA9A 2ETDA 2QGMA 3IAM1 3DA4A 4HEA1 5FZTA 2YFAA 3DA3A 5HXHA 4G75A 4DWLA 3AT7A 3PF0A 2F66B 2JB2A 3DYJA 2JBWA 4ECGA 2P22B 4BGOA 2ZRRA 2XTRA 5LNK1 2KBBA 3F4MA 2K19A 4OAUC 4YZ9A 2BL8A 3V5UA 2RLDA 3FYQA 2JB3A 4Q9VA 4YZCA 3LJ0A 3WURA 2QZGA 3Q8DA 5HWXA 1SJ8A 1YO7A 5JDGA 3LJ1A 3FNBA 1W3SA
chains in the Genus database with same CATH topology
3DO9A 3KP9A 2L10A 4PL4A 3AJFA 2JAEA 2A2DA 3AY5A 2KGXA 2MJFB 1SJ7A 2V6EA 4HFVA 4PL5A 4Z7GA 4NV2A 4W8PA 2XTQA 3LJ2A 2RIOA 3IAS1 2KVPA 4G76A 4AS2A 3SDJA 3I9V1 2V1CC 4JCVE 4NV5A 3FBVA 4GXTA 4F7GB 4AS3A 4U6RA 2F6MB 5HGIA 2L7NA 4O1OA 4OAVB 2JB1A 4YZDA 4Z7HA 2KKMA 2A2CA 2L1LB 3P23A 2XMXA 1U5KA 3L0IA 4O1PA 2YFBA 3JSBA 2FUG1 4I1TA 4PL3A 2E8GA 3UITA 2IP6A 2X0CA 2CAZB 3VA9A 3IAM1 4HEA1 3DA4A 5FZTA 2YFAA 3DA3A 4G75A 4DWLA 2F66B 2JB2A 3DYJA 2P22B 2ZRRA 2XTRA 5LNK1 2KBBA 3F4MA 2K19A 4OAUC 4YZ9A 3FYQA 2JB3A 4Q9VA 4YZCA 3LJ0A 3Q8DA 1SJ8A 1YO7A 3LJ1A 1W3SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SJ8 A;  2L7N A;  4F7G B;  1YO7 A;  5FZT A;  2L10 A;  4W8P A;  2KBB A;  3AY5 A;  2X0C A;  3FYQ A;  2KGX A;  3DYJ A;  2KVP A;  1SJ7 A; 
#chains in the Genus database with same CATH topology
 3DO9 A;  3KP9 A;  4ONR A;  3WSC A;  2L10 A;  3PHF 1;  3V5S A;  4PL4 A;  2ZW3 A;  3AJF A;  2XQY A;  2JAE A;  2FU2 A;  5JDF A;  5JDL A;  5HXS A;  5JDQ A;  2A2D A;  5JDH A;  3AY5 A;  3B55 A;  2KGX A;  2MJF B;  1SJ7 A;  2V6E A;  4HFV A;  4PL5 A;  4Z7G A;  1JQO A;  5HXE A;  4NV2 A;  4W8P A;  2QSB A;  2XTQ A;  3LJ2 A;  2RIO A;  2RAD A;  3VJZ A;  2FEF A;  3IAS 1;  2GSC A;  2KVP A;  5T1D A;  4G76 A;  4AS2 A;  3SDJ A;  1TDP A;  3I9V 1;  2V1C C;  4JCV E;  4NV5 A;  2LQU A;  3FBV A;  5JDN A;  4GXT A;  4F7G B;  4AS3 A;  3M1C A;  5JDM A;  2HGK A;  2F6M B;  4U6R A;  5HGI A;  2L7N A;  4O1O A;  4OAV B;  5HWY A;  2JB1 A;  4YZD A;  4Z7H A;  2KKM A;  2A2C A;  5HXC A;  2L1L B;  3P23 A;  2XMX A;  3FVV A;  1U5K A;  3L0I A;  4O1P A;  2YFB A;  3JSB A;  2FUG 1;  4I1T A;  5HXR A;  5HYA A;  4PL3 A;  2BL7 A;  2E8G A;  3UIT A;  2IP6 A;  2X0C A;  2CAZ B;  2MTC A;  3VA9 A;  2ETD A;  2QGM A;  3IAM 1;  3DA4 A;  4HEA 1;  5FZT A;  2YFA A;  3DA3 A;  5HXH A;  4G75 A;  4DWL A;  3AT7 A;  3PF0 A;  2F66 B;  2JB2 A;  3DYJ A;  2JBW A;  4ECG A;  2P22 B;  4BGO A;  2ZRR A;  2XTR A;  5LNK 1;  2KBB A;  3F4M A;  2K19 A;  4OAU C;  4YZ9 A;  2BL8 A;  3V5U A;  2RLD A;  3FYQ A;  2JB3 A;  4Q9V A;  4YZC A;  3LJ0 A;  3WUR A;  2QZG A;  3Q8D A;  5HWX A;  1SJ8 A;  1YO7 A;  5JDG A;  3LJ1 A;  3FNB A;  1W3S A; 
#chains in the Genus database with same CATH homology
 3DO9 A;  3KP9 A;  2L10 A;  4PL4 A;  3AJF A;  2JAE A;  2A2D A;  3AY5 A;  2KGX A;  2MJF B;  1SJ7 A;  2V6E A;  4HFV A;  4PL5 A;  4Z7G A;  4NV2 A;  4W8P A;  2XTQ A;  3LJ2 A;  2RIO A;  3IAS 1;  2KVP A;  4G76 A;  4AS2 A;  3SDJ A;  3I9V 1;  2V1C C;  4JCV E;  4NV5 A;  3FBV A;  4GXT A;  4F7G B;  4AS3 A;  4U6R A;  2F6M B;  5HGI A;  2L7N A;  4O1O A;  4OAV B;  2JB1 A;  4YZD A;  4Z7H A;  2KKM A;  2A2C A;  2L1L B;  3P23 A;  2XMX A;  1U5K A;  3L0I A;  4O1P A;  2YFB A;  3JSB A;  2FUG 1;  4I1T A;  4PL3 A;  2E8G A;  3UIT A;  2IP6 A;  2X0C A;  2CAZ B;  3VA9 A;  3IAM 1;  4HEA 1;  3DA4 A;  5FZT A;  2YFA A;  3DA3 A;  4G75 A;  4DWL A;  2F66 B;  2JB2 A;  3DYJ A;  2P22 B;  2ZRR A;  2XTR A;  5LNK 1;  2KBB A;  3F4M A;  2K19 A;  4OAU C;  4YZ9 A;  3FYQ A;  2JB3 A;  4Q9V A;  4YZC A;  3LJ0 A;  3Q8D A;  1SJ8 A;  1YO7 A;  3LJ1 A;  1W3S A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...