1YI2E

Crystal structure of erythromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 38
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 38
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2005-01-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yi2E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yi2E01
1M90G 1VQLE 4WFNE 1Q82G 2QA4E 1NJIG 2QEXE 3CXCE 1VQ6E 5DM7E 3CMAE 4UY8G 4WFBE 2ZJRE 1Q81G 3CCQE 1VQME 3CCUE 1K73G 1VQOE 1VQNE 3CCVE 2OTLE 3CF5E 3G4SE 5GAEG 3CC4E 1QVGE 3J7ZG 1YJNE 4WFAE 1YITE 4IOAE 1VQ8E 3OW2E 3CC2E 1VQPE 1KD1G 5DM6E 1N8RG 2ZJQE 1VQ9E 1YJWE 3CCLE 1Q86G 1YJ9E 4IOCE 3CCEE 3PIOE 2CQLA 1VQKE 1VQ5E 3I55E 3CD6E 1K8AG 1W2BE 3CCRE 4IO9E 4U67E 1YHQE 5JVHE 5GADG 1VQ4E 3CCSE 1YIJE 3CCME 1M1KG 1KC8G 5HL7E 1RL6A 5AN9B 3CMEE 3I56E 5GAHG 4WCEE 3G71E 3G6EE 1YI2E 2ZJPE 1K9MG 5H1SI 3CCJE 3PIPE 1JJ2E 3DLLE 4WF9E 3CPWE 1KQSE 1S72E 5MLCH 3CC7E 5JVGE 5GAGG 1VQ7E 1QVFE 2OTJE 1Q7YG
chains in the Genus database with same CATH superfamily
1M90G 1VQLE 4WFNE 1Q82G 2QA4E 1NJIG 2QEXE 3CXCE 2OY7A 1VQ6E 5DM7E 3CMAE 4UY8G 2FKGA 4WFBE 2ZJRE 1Q81G 3CCQE 1VQME 3CCUE 1K73G 1VQOE 1VQNE 3CCVE 2OTLE 3CF5E 3G4SE 2OYBO 3IG9A 2OL7A 5GAEG 3CC4E 1QVGE 3J7ZG 1YJNE 4WFAE 2FKJA 1P4PA 1YITE 1RJLC 4IOAE 1VQ8E 3OW2E 3CC2E 1VQPE 1KD1G 1FJ1E 5DM6E 1N8RG 2ZJQE 5B2AO 1VQ9E 1YJWE 3CCLE 2OY5O 1Q86G 2OY8A 1YJ9E 4IOCE 3CCEE 3PIOE 2CQLA 1VQKE 1VQ5E 5B10O 3I55E 2G8CO 2OL6O 3CD6E 1K8AG 1W2BE 3CCRE 4IO9E 4U67E 1YHQE 5JVHE 5GADG 2AF5A 3CCSE 1VQ4E 1YIJE 3CCME 1M1KG 1KC8G 2HKDA 5HL7E 1RL6A 5AN9B 2I5VO 3CMEE 1OSPO 3I56E 3EC5A 5GAHG 2OY1O 2I5ZO 4WCEE 3G71E 3CKGA 3AUMO 3G6EE 2OL8O 1YI2E 2ZJPE 3IGEA 1K9MG 5H1SI 3CCJE 3PIPE 1JJ2E 2PI3O 3DLLE 5B11O 4WF9E 3CPWE 1KQSE 1S72E 5MLCH 5B3MO 3CC7E 5JVGE 5GAGG 1VQ7E 3CKFA 1QVFE 2OTJE 1Q7YG
chains in the Genus database with same CATH topology
1M90G 1VQLE 4WFNE 1Q82G 2QA4E 1NJIG 2QEXE 3CXCE 1VQ6E 5DM7E 3CMAE 4UY8G 4WFBE 2ZJRE 1Q81G 3CCQE 1VQME 3CCUE 1K73G 1VQOE 1VQNE 3CCVE 2OTLE 3CF5E 3G4SE 5GAEG 3CC4E 1QVGE 3J7ZG 1YJNE 4WFAE 1YITE 4IOAE 1VQ8E 3OW2E 3CC2E 1VQPE 1KD1G 5DM6E 1N8RG 2ZJQE 1VQ9E 1YJWE 3CCLE 1Q86G 1YJ9E 4IOCE 3CCEE 3PIOE 2CQLA 1VQKE 1VQ5E 3I55E 3CD6E 1K8AG 1W2BE 3CCRE 4IO9E 4U67E 1YHQE 5JVHE 5GADG 1VQ4E 3CCSE 1YIJE 3CCME 1M1KG 1KC8G 5HL7E 1RL6A 5AN9B 3CMEE 3I56E 5GAHG 4WCEE 3G71E 3G6EE 1YI2E 2ZJPE 1K9MG 5H1SI 3CCJE 3PIPE 1JJ2E 3DLLE 4WF9E 3CPWE 1KQSE 1S72E 5MLCH 3CC7E 5JVGE 5GAGG 1VQ7E 1QVFE 2OTJE 1Q7YG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M90 G;  1VQL E;  4WFN E;  1Q82 G;  2QA4 E;  1NJI G;  2QEX E;  3CXC E;  1VQ6 E;  5DM7 E;  3CMA E;  4UY8 G;  4WFB E;  2ZJR E;  1Q81 G;  3CCQ E;  1VQM E;  3CCU E;  1K73 G;  1VQO E;  1VQN E;  3CCV E;  2OTL E;  3CF5 E;  3G4S E;  5GAE G;  3CC4 E;  1QVG E;  3J7Z G;  1YJN E;  4WFA E;  1YIT E;  4IOA E;  1VQ8 E;  3OW2 E;  3CC2 E;  1VQP E;  1KD1 G;  5DM6 E;  1N8R G;  2ZJQ E;  1VQ9 E;  1YJW E;  3CCL E;  1Q86 G;  1YJ9 E;  4IOC E;  3CCE E;  3PIO E;  2CQL A;  1VQK E;  1VQ5 E;  3I55 E;  3CD6 E;  1K8A G;  1W2B E;  3CCR E;  4IO9 E;  4U67 E;  1YHQ E;  5JVH E;  5GAD G;  1VQ4 E;  3CCS E;  1YIJ E;  3CCM E;  1M1K G;  1KC8 G;  5HL7 E;  1RL6 A;  5AN9 B;  3CME E;  3I56 E;  5GAH G;  4WCE E;  3G71 E;  3G6E E;  1YI2 E;  2ZJP E;  1K9M G;  5H1S I;  3CCJ E;  3PIP E;  1JJ2 E;  3DLL E;  4WF9 E;  3CPW E;  1KQS E;  1S72 E;  5MLC H;  3CC7 E;  5JVG E;  5GAG G;  1VQ7 E;  1QVF E;  2OTJ E;  1Q7Y G; 
#chains in the Genus database with same CATH topology
 1M90 G;  1VQL E;  4WFN E;  1Q82 G;  2QA4 E;  1NJI G;  2QEX E;  3CXC E;  2OY7 A;  1VQ6 E;  5DM7 E;  3CMA E;  4UY8 G;  2FKG A;  4WFB E;  2ZJR E;  1Q81 G;  3CCQ E;  1VQM E;  3CCU E;  1K73 G;  1VQO E;  1VQN E;  3CCV E;  2OTL E;  3CF5 E;  3G4S E;  2OYB O;  3IG9 A;  2OL7 A;  5GAE G;  3CC4 E;  1QVG E;  3J7Z G;  1YJN E;  4WFA E;  2FKJ A;  1P4P A;  1YIT E;  1RJL C;  4IOA E;  1VQ8 E;  3OW2 E;  3CC2 E;  1VQP E;  1KD1 G;  1FJ1 E;  5DM6 E;  1N8R G;  2ZJQ E;  5B2A O;  1VQ9 E;  1YJW E;  3CCL E;  2OY5 O;  1Q86 G;  2OY8 A;  1YJ9 E;  4IOC E;  3CCE E;  3PIO E;  2CQL A;  1VQK E;  1VQ5 E;  5B10 O;  3I55 E;  2G8C O;  2OL6 O;  3CD6 E;  1K8A G;  1W2B E;  3CCR E;  4IO9 E;  4U67 E;  1YHQ E;  5JVH E;  5GAD G;  2AF5 A;  3CCS E;  1VQ4 E;  1YIJ E;  3CCM E;  1M1K G;  1KC8 G;  2HKD A;  5HL7 E;  1RL6 A;  5AN9 B;  2I5V O;  3CME E;  1OSP O;  3I56 E;  3EC5 A;  5GAH G;  2OY1 O;  2I5Z O;  4WCE E;  3G71 E;  3CKG A;  3AUM O;  3G6E E;  2OL8 O;  1YI2 E;  2ZJP E;  3IGE A;  1K9M G;  5H1S I;  3CCJ E;  3PIP E;  1JJ2 E;  2PI3 O;  3DLL E;  5B11 O;  4WF9 E;  3CPW E;  1KQS E;  1S72 E;  5MLC H;  5B3M O;  3CC7 E;  5JVG E;  5GAG G;  1VQ7 E;  3CKF A;  1QVF E;  2OTJ E;  1Q7Y G; 
#chains in the Genus database with same CATH homology
 1M90 G;  1VQL E;  4WFN E;  1Q82 G;  2QA4 E;  1NJI G;  2QEX E;  3CXC E;  1VQ6 E;  5DM7 E;  3CMA E;  4UY8 G;  4WFB E;  2ZJR E;  1Q81 G;  3CCQ E;  1VQM E;  3CCU E;  1K73 G;  1VQO E;  1VQN E;  3CCV E;  2OTL E;  3CF5 E;  3G4S E;  5GAE G;  3CC4 E;  1QVG E;  3J7Z G;  1YJN E;  4WFA E;  1YIT E;  4IOA E;  1VQ8 E;  3OW2 E;  3CC2 E;  1VQP E;  1KD1 G;  5DM6 E;  1N8R G;  2ZJQ E;  1VQ9 E;  1YJW E;  3CCL E;  1Q86 G;  1YJ9 E;  4IOC E;  3CCE E;  3PIO E;  2CQL A;  1VQK E;  1VQ5 E;  3I55 E;  3CD6 E;  1K8A G;  1W2B E;  3CCR E;  4IO9 E;  4U67 E;  1YHQ E;  5JVH E;  5GAD G;  1VQ4 E;  3CCS E;  1YIJ E;  3CCM E;  1M1K G;  1KC8 G;  5HL7 E;  1RL6 A;  5AN9 B;  3CME E;  3I56 E;  5GAH G;  4WCE E;  3G71 E;  3G6E E;  1YI2 E;  2ZJP E;  1K9M G;  5H1S I;  3CCJ E;  3PIP E;  1JJ2 E;  3DLL E;  4WF9 E;  3CPW E;  1KQS E;  1S72 E;  5MLC H;  3CC7 E;  5JVG E;  5GAG G;  1VQ7 E;  1QVF E;  2OTJ E;  1Q7Y G; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...