3CCLE

Structure of anisomycin resistant 50s ribosomal subunit: 23s rrna mutation u2535c. density for anisomycin is visible but not included in model.
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2P
total genus 38
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2008-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cclE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 3cclE01
4WFAE 3CCSE 3CCRE 1K73G 3I55E 3PIOE 3CF5E 5GAGG 3J7ZG 3G4SE 2ZJRE 1RL6A 5GAHG 3CMAE 1VQ7E 3CCJE 1VQLE 1M90G 4WF9E 1K9MG 3DLLE 5GAEG 2CQLA 2QA4E 2QEXE 1NJIG 4UY8G 3I56E 4WFNE 1VQKE 3CC4E 1VQ6E 5GADG 2OTJE 5DM7E 5MLCH 1YJNE 1Q82G 1KQSE 1QVFE 1YI2E 1Q7YG 1N8RG 1Q81G 3CCME 5AN9B 1QVGE 1VQOE 3CXCE 3CCVE 2OTLE 1W2BE 1Q86G 1K8AG 4IOAE 5JVHE 5HL7E 4IOCE 1S72E 1YIJE 5DM6E 1KD1G 1VQ9E 1YJ9E 1KC8G 3CC2E 1VQNE 1VQ8E 4WCEE 3CCQE 3CCUE 3CMEE 3CCLE 1VQPE 5H1SI 1M1KG 3CC7E 1VQ5E 3CD6E 1YITE 3G6EE 5JVGE 1YJWE 3CCEE 3G71E 1YHQE 3OW2E 4WFBE 4IO9E 2ZJQE 3PIPE 1JJ2E 4U67E 3CPWE 1VQ4E 1VQME 2ZJPE
chains in the Genus database with same CATH superfamily
4WFAE 3CCSE 3CCRE 1K73G 3I55E 2OY7A 3PIOE 3CF5E 5GAGG 3J7ZG 3G4SE 5B10O 2ZJRE 1RL6A 2OY1O 2I5VO 5GAHG 3CMAE 1VQ7E 3IGEA 3AUMO 3CCJE 1VQLE 2OY8A 1P4PA 1M90G 4WF9E 1K9MG 3DLLE 5GAEG 2CQLA 2QA4E 3CKFA 2HKDA 2QEXE 1NJIG 4UY8G 3I56E 4WFNE 1VQKE 3CC4E 1VQ6E 5GADG 2OTJE 5DM7E 5MLCH 1YJNE 1Q82G 1RJLC 1KQSE 1QVFE 1YI2E 1Q7YG 1N8RG 1Q81G 3CCME 5AN9B 1QVGE 5B11O 1VQOE 3CXCE 2FKGA 3CCVE 2OTLE 1W2BE 1Q86G 1K8AG 4IOAE 5JVHE 3EC5A 5HL7E 4IOCE 2OYBO 2FKJA 1S72E 2G8CO 1YIJE 2OL7A 5DM6E 1KD1G 1VQ9E 1YJ9E 1KC8G 3CC2E 1VQNE 2I5ZO 5B2AO 1VQ8E 4WCEE 3CCQE 3CCUE 5B3MO 3CMEE 3CCLE 1VQPE 5H1SI 1M1KG 3CC7E 1VQ5E 2OL6O 2AF5A 3CD6E 1YITE 3IG9A 3G6EE 5JVGE 1YJWE 1FJ1E 2OL8O 3CCEE 3G71E 1YHQE 3OW2E 3CKGA 4WFBE 4IO9E 2ZJQE 2OY5O 1OSPO 2PI3O 3PIPE 1JJ2E 4U67E 3CPWE 1VQ4E 1VQME 2ZJPE
chains in the Genus database with same CATH topology
4WFAE 3CCSE 3CCRE 1K73G 3I55E 3PIOE 3CF5E 5GAGG 3J7ZG 3G4SE 2ZJRE 1RL6A 5GAHG 3CMAE 1VQ7E 3CCJE 1VQLE 1M90G 4WF9E 1K9MG 3DLLE 5GAEG 2CQLA 2QA4E 2QEXE 1NJIG 4UY8G 3I56E 4WFNE 1VQKE 3CC4E 1VQ6E 5GADG 2OTJE 5DM7E 5MLCH 1YJNE 1Q82G 1KQSE 1QVFE 1YI2E 1Q7YG 1N8RG 1Q81G 3CCME 5AN9B 1QVGE 1VQOE 3CXCE 3CCVE 2OTLE 1W2BE 1Q86G 1K8AG 4IOAE 5JVHE 5HL7E 4IOCE 1S72E 1YIJE 5DM6E 1KD1G 1VQ9E 1YJ9E 1KC8G 3CC2E 1VQNE 1VQ8E 4WCEE 3CCQE 3CCUE 3CMEE 3CCLE 1VQPE 5H1SI 1M1KG 3CC7E 1VQ5E 3CD6E 1YITE 3G6EE 5JVGE 1YJWE 3CCEE 3G71E 1YHQE 3OW2E 4WFBE 4IO9E 2ZJQE 3PIPE 1JJ2E 4U67E 3CPWE 1VQ4E 1VQME 2ZJPE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFA E;  3CCS E;  3CCR E;  1K73 G;  3I55 E;  3PIO E;  3CF5 E;  5GAG G;  3J7Z G;  3G4S E;  2ZJR E;  1RL6 A;  5GAH G;  3CMA E;  1VQ7 E;  3CCJ E;  1VQL E;  1M90 G;  4WF9 E;  1K9M G;  3DLL E;  5GAE G;  2CQL A;  2QA4 E;  2QEX E;  1NJI G;  4UY8 G;  3I56 E;  4WFN E;  1VQK E;  3CC4 E;  1VQ6 E;  5GAD G;  2OTJ E;  5DM7 E;  5MLC H;  1YJN E;  1Q82 G;  1KQS E;  1QVF E;  1YI2 E;  1Q7Y G;  1N8R G;  1Q81 G;  3CCM E;  5AN9 B;  1QVG E;  1VQO E;  3CXC E;  3CCV E;  2OTL E;  1W2B E;  1Q86 G;  1K8A G;  4IOA E;  5JVH E;  5HL7 E;  4IOC E;  1S72 E;  1YIJ E;  5DM6 E;  1KD1 G;  1VQ9 E;  1YJ9 E;  1KC8 G;  3CC2 E;  1VQN E;  1VQ8 E;  4WCE E;  3CCQ E;  3CCU E;  3CME E;  3CCL E;  1VQP E;  5H1S I;  1M1K G;  3CC7 E;  1VQ5 E;  3CD6 E;  1YIT E;  3G6E E;  5JVG E;  1YJW E;  3CCE E;  3G71 E;  1YHQ E;  3OW2 E;  4WFB E;  4IO9 E;  2ZJQ E;  3PIP E;  1JJ2 E;  4U67 E;  3CPW E;  1VQ4 E;  1VQM E;  2ZJP E; 
#chains in the Genus database with same CATH topology
 4WFA E;  3CCS E;  3CCR E;  1K73 G;  3I55 E;  2OY7 A;  3PIO E;  3CF5 E;  5GAG G;  3J7Z G;  3G4S E;  5B10 O;  2ZJR E;  1RL6 A;  2OY1 O;  2I5V O;  5GAH G;  3CMA E;  1VQ7 E;  3IGE A;  3AUM O;  3CCJ E;  1VQL E;  2OY8 A;  1P4P A;  1M90 G;  4WF9 E;  1K9M G;  3DLL E;  5GAE G;  2CQL A;  2QA4 E;  3CKF A;  2HKD A;  2QEX E;  1NJI G;  4UY8 G;  3I56 E;  4WFN E;  1VQK E;  3CC4 E;  1VQ6 E;  5GAD G;  2OTJ E;  5DM7 E;  5MLC H;  1YJN E;  1Q82 G;  1RJL C;  1KQS E;  1QVF E;  1YI2 E;  1Q7Y G;  1N8R G;  1Q81 G;  3CCM E;  5AN9 B;  1QVG E;  5B11 O;  1VQO E;  3CXC E;  2FKG A;  3CCV E;  2OTL E;  1W2B E;  1Q86 G;  1K8A G;  4IOA E;  5JVH E;  3EC5 A;  5HL7 E;  4IOC E;  2OYB O;  2FKJ A;  1S72 E;  2G8C O;  1YIJ E;  2OL7 A;  5DM6 E;  1KD1 G;  1VQ9 E;  1YJ9 E;  1KC8 G;  3CC2 E;  1VQN E;  2I5Z O;  5B2A O;  1VQ8 E;  4WCE E;  3CCQ E;  3CCU E;  5B3M O;  3CME E;  3CCL E;  1VQP E;  5H1S I;  1M1K G;  3CC7 E;  1VQ5 E;  2OL6 O;  2AF5 A;  3CD6 E;  1YIT E;  3IG9 A;  3G6E E;  5JVG E;  1YJW E;  1FJ1 E;  2OL8 O;  3CCE E;  3G71 E;  1YHQ E;  3OW2 E;  3CKG A;  4WFB E;  4IO9 E;  2ZJQ E;  2OY5 O;  1OSP O;  2PI3 O;  3PIP E;  1JJ2 E;  4U67 E;  3CPW E;  1VQ4 E;  1VQM E;  2ZJP E; 
#chains in the Genus database with same CATH homology
 4WFA E;  3CCS E;  3CCR E;  1K73 G;  3I55 E;  3PIO E;  3CF5 E;  5GAG G;  3J7Z G;  3G4S E;  2ZJR E;  1RL6 A;  5GAH G;  3CMA E;  1VQ7 E;  3CCJ E;  1VQL E;  1M90 G;  4WF9 E;  1K9M G;  3DLL E;  5GAE G;  2CQL A;  2QA4 E;  2QEX E;  1NJI G;  4UY8 G;  3I56 E;  4WFN E;  1VQK E;  3CC4 E;  1VQ6 E;  5GAD G;  2OTJ E;  5DM7 E;  5MLC H;  1YJN E;  1Q82 G;  1KQS E;  1QVF E;  1YI2 E;  1Q7Y G;  1N8R G;  1Q81 G;  3CCM E;  5AN9 B;  1QVG E;  1VQO E;  3CXC E;  3CCV E;  2OTL E;  1W2B E;  1Q86 G;  1K8A G;  4IOA E;  5JVH E;  5HL7 E;  4IOC E;  1S72 E;  1YIJ E;  5DM6 E;  1KD1 G;  1VQ9 E;  1YJ9 E;  1KC8 G;  3CC2 E;  1VQN E;  1VQ8 E;  4WCE E;  3CCQ E;  3CCU E;  3CME E;  3CCL E;  1VQP E;  5H1S I;  1M1K G;  3CC7 E;  1VQ5 E;  3CD6 E;  1YIT E;  3G6E E;  5JVG E;  1YJW E;  3CCE E;  3G71 E;  1YHQ E;  3OW2 E;  4WFB E;  4IO9 E;  2ZJQ E;  3PIP E;  1JJ2 E;  4U67 E;  3CPW E;  1VQ4 E;  1VQM E;  2ZJP E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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