1YIJE

Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2005-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yijE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yijE01
3PIOE 5DM6E 5GADG 5MLCH 1VQKE 1K9MG 5JVGE 4UY8G 1W2BE 3CCVE 4WFAE 1VQ9E 4WCEE 1Q7YG 1QVFE 2QEXE 4IO9E 1NJIG 1Q86G 3PIPE 1VQOE 1QVGE 1K73G 2OTJE 3CCJE 1YJWE 2ZJRE 5DM7E 4IOAE 5H1SI 3G71E 1YIJE 1RL6A 4WFBE 1S72E 1VQ5E 2CQLA 3I55E 3CC4E 3CC7E 3CPWE 1YI2E 3CMAE 3CCUE 2OTLE 4WFNE 4IOCE 2ZJQE 3CCSE 4WF9E 5GAHG 1JJ2E 3G4SE 2QA4E 1VQNE 3OW2E 1VQ4E 2ZJPE 3J7ZG 1KC8G 5AN9B 1VQ6E 1VQME 1VQ7E 5HL7E 1M1KG 1VQPE 1YJ9E 3CXCE 3CCEE 3CCME 4U67E 1Q81G 1M90G 1Q82G 1K8AG 1YHQE 3CCRE 3CF5E 1YJNE 5GAGG 3CCQE 5JVHE 1YITE 5GAEG 1N8RG 3I56E 1VQ8E 3CCLE 1KD1G 3CC2E 1VQLE 1KQSE 3CMEE 3DLLE 3CD6E 3G6EE
chains in the Genus database with same CATH superfamily
1FJ1E 3PIOE 5DM6E 5GADG 5MLCH 1VQKE 2OL7A 1K9MG 5JVGE 2I5ZO 4UY8G 2OY5O 1W2BE 3CCVE 4WFAE 1P4PA 1VQ9E 5B3MO 4WCEE 5B10O 1Q7YG 1QVFE 2QEXE 2FKJA 4IO9E 1NJIG 1Q86G 3PIPE 1VQOE 1QVGE 5B11O 3CKFA 1K73G 2PI3O 2OTJE 3CCJE 1YJWE 2ZJRE 5DM7E 4IOAE 5H1SI 3G71E 1YIJE 1RL6A 4WFBE 1S72E 1VQ5E 2CQLA 3I55E 3IG9A 3CC4E 3CC7E 2OY1O 3CKGA 3CPWE 1YI2E 3CMAE 3CCUE 2OTLE 1OSPO 4WFNE 4IOCE 3IGEA 2ZJQE 3CCSE 4WF9E 5GAHG 1JJ2E 3G4SE 2QA4E 1VQNE 3OW2E 1VQ4E 2ZJPE 2OL8O 3J7ZG 1KC8G 5AN9B 1RJLC 1VQ6E 1VQME 1VQ7E 5HL7E 1M1KG 1VQPE 2OY8A 1YJ9E 3CXCE 3CCEE 2FKGA 5B2AO 3CCME 2AF5A 4U67E 1Q81G 3EC5A 1M90G 1Q82G 1K8AG 1YHQE 2HKDA 3CCRE 3CF5E 1YJNE 5GAGG 3CCQE 5JVHE 1YITE 5GAEG 1N8RG 3I56E 1VQ8E 3CCLE 1KD1G 3AUMO 3CC2E 1VQLE 2G8CO 1KQSE 3CMEE 2I5VO 3DLLE 3CD6E 2OY7A 3G6EE 2OL6O 2OYBO
chains in the Genus database with same CATH topology
3PIOE 5DM6E 5GADG 5MLCH 1VQKE 1K9MG 5JVGE 4UY8G 1W2BE 3CCVE 4WFAE 1VQ9E 4WCEE 1Q7YG 1QVFE 2QEXE 4IO9E 1NJIG 1Q86G 3PIPE 1VQOE 1QVGE 1K73G 2OTJE 3CCJE 1YJWE 2ZJRE 5DM7E 4IOAE 5H1SI 3G71E 1YIJE 1RL6A 4WFBE 1S72E 1VQ5E 2CQLA 3I55E 3CC4E 3CC7E 3CPWE 1YI2E 3CMAE 3CCUE 2OTLE 4WFNE 4IOCE 2ZJQE 3CCSE 4WF9E 5GAHG 1JJ2E 3G4SE 2QA4E 1VQNE 3OW2E 1VQ4E 2ZJPE 3J7ZG 1KC8G 5AN9B 1VQ6E 1VQME 1VQ7E 5HL7E 1M1KG 1VQPE 1YJ9E 3CXCE 3CCEE 3CCME 4U67E 1Q81G 1M90G 1Q82G 1K8AG 1YHQE 3CCRE 3CF5E 1YJNE 5GAGG 3CCQE 5JVHE 1YITE 5GAEG 1N8RG 3I56E 1VQ8E 3CCLE 1KD1G 3CC2E 1VQLE 1KQSE 3CMEE 3DLLE 3CD6E 3G6EE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PIO E;  5DM6 E;  5GAD G;  5MLC H;  1VQK E;  1K9M G;  5JVG E;  4UY8 G;  1W2B E;  3CCV E;  4WFA E;  1VQ9 E;  4WCE E;  1Q7Y G;  1QVF E;  2QEX E;  4IO9 E;  1NJI G;  1Q86 G;  3PIP E;  1VQO E;  1QVG E;  1K73 G;  2OTJ E;  3CCJ E;  1YJW E;  2ZJR E;  5DM7 E;  4IOA E;  5H1S I;  3G71 E;  1YIJ E;  1RL6 A;  4WFB E;  1S72 E;  1VQ5 E;  2CQL A;  3I55 E;  3CC4 E;  3CC7 E;  3CPW E;  1YI2 E;  3CMA E;  3CCU E;  2OTL E;  4WFN E;  4IOC E;  2ZJQ E;  3CCS E;  4WF9 E;  5GAH G;  1JJ2 E;  3G4S E;  2QA4 E;  1VQN E;  3OW2 E;  1VQ4 E;  2ZJP E;  3J7Z G;  1KC8 G;  5AN9 B;  1VQ6 E;  1VQM E;  1VQ7 E;  5HL7 E;  1M1K G;  1VQP E;  1YJ9 E;  3CXC E;  3CCE E;  3CCM E;  4U67 E;  1Q81 G;  1M90 G;  1Q82 G;  1K8A G;  1YHQ E;  3CCR E;  3CF5 E;  1YJN E;  5GAG G;  3CCQ E;  5JVH E;  1YIT E;  5GAE G;  1N8R G;  3I56 E;  1VQ8 E;  3CCL E;  1KD1 G;  3CC2 E;  1VQL E;  1KQS E;  3CME E;  3DLL E;  3CD6 E;  3G6E E; 
#chains in the Genus database with same CATH topology
 1FJ1 E;  3PIO E;  5DM6 E;  5GAD G;  5MLC H;  1VQK E;  2OL7 A;  1K9M G;  5JVG E;  2I5Z O;  4UY8 G;  2OY5 O;  1W2B E;  3CCV E;  4WFA E;  1P4P A;  1VQ9 E;  5B3M O;  4WCE E;  5B10 O;  1Q7Y G;  1QVF E;  2QEX E;  2FKJ A;  4IO9 E;  1NJI G;  1Q86 G;  3PIP E;  1VQO E;  1QVG E;  5B11 O;  3CKF A;  1K73 G;  2PI3 O;  2OTJ E;  3CCJ E;  1YJW E;  2ZJR E;  5DM7 E;  4IOA E;  5H1S I;  3G71 E;  1YIJ E;  1RL6 A;  4WFB E;  1S72 E;  1VQ5 E;  2CQL A;  3I55 E;  3IG9 A;  3CC4 E;  3CC7 E;  2OY1 O;  3CKG A;  3CPW E;  1YI2 E;  3CMA E;  3CCU E;  2OTL E;  1OSP O;  4WFN E;  4IOC E;  3IGE A;  2ZJQ E;  3CCS E;  4WF9 E;  5GAH G;  1JJ2 E;  3G4S E;  2QA4 E;  1VQN E;  3OW2 E;  1VQ4 E;  2ZJP E;  2OL8 O;  3J7Z G;  1KC8 G;  5AN9 B;  1RJL C;  1VQ6 E;  1VQM E;  1VQ7 E;  5HL7 E;  1M1K G;  1VQP E;  2OY8 A;  1YJ9 E;  3CXC E;  3CCE E;  2FKG A;  5B2A O;  3CCM E;  2AF5 A;  4U67 E;  1Q81 G;  3EC5 A;  1M90 G;  1Q82 G;  1K8A G;  1YHQ E;  2HKD A;  3CCR E;  3CF5 E;  1YJN E;  5GAG G;  3CCQ E;  5JVH E;  1YIT E;  5GAE G;  1N8R G;  3I56 E;  1VQ8 E;  3CCL E;  1KD1 G;  3AUM O;  3CC2 E;  1VQL E;  2G8C O;  1KQS E;  3CME E;  2I5V O;  3DLL E;  3CD6 E;  2OY7 A;  3G6E E;  2OL6 O;  2OYB O; 
#chains in the Genus database with same CATH homology
 3PIO E;  5DM6 E;  5GAD G;  5MLC H;  1VQK E;  1K9M G;  5JVG E;  4UY8 G;  1W2B E;  3CCV E;  4WFA E;  1VQ9 E;  4WCE E;  1Q7Y G;  1QVF E;  2QEX E;  4IO9 E;  1NJI G;  1Q86 G;  3PIP E;  1VQO E;  1QVG E;  1K73 G;  2OTJ E;  3CCJ E;  1YJW E;  2ZJR E;  5DM7 E;  4IOA E;  5H1S I;  3G71 E;  1YIJ E;  1RL6 A;  4WFB E;  1S72 E;  1VQ5 E;  2CQL A;  3I55 E;  3CC4 E;  3CC7 E;  3CPW E;  1YI2 E;  3CMA E;  3CCU E;  2OTL E;  4WFN E;  4IOC E;  2ZJQ E;  3CCS E;  4WF9 E;  5GAH G;  1JJ2 E;  3G4S E;  2QA4 E;  1VQN E;  3OW2 E;  1VQ4 E;  2ZJP E;  3J7Z G;  1KC8 G;  5AN9 B;  1VQ6 E;  1VQM E;  1VQ7 E;  5HL7 E;  1M1K G;  1VQP E;  1YJ9 E;  3CXC E;  3CCE E;  3CCM E;  4U67 E;  1Q81 G;  1M90 G;  1Q82 G;  1K8A G;  1YHQ E;  3CCR E;  3CF5 E;  1YJN E;  5GAG G;  3CCQ E;  5JVH E;  1YIT E;  5GAE G;  1N8R G;  3I56 E;  1VQ8 E;  3CCL E;  1KD1 G;  3CC2 E;  1VQL E;  1KQS E;  3CME E;  3DLL E;  3CD6 E;  3G6E E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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