1YIJE

Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosome
publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule keywords 23S Ribosomal RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2005-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yijE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yijE01
3G6EE 4UY8G 4WFBE 3CCSE 3CPWE 4IO9E 1VQME 2ZJRE 3CF5E 1Q81G 3CCME 1RL6A 3CCEE 5DM7E 1NJIG 4WCEE 3CCLE 3CCQE 3CD6E 4WF9E 4WFAE 1VQ9E 1VQ5E 4U67E 3I56E 1VQNE 3CC4E 3PIOE 3G71E 5H1SI 2ZJQE 1YJWE 2QA4E 4IOAE 1VQPE 3I55E 1Q82G 4WFNE 1N8RG 3CC7E 1YIJE 3J7ZG 4IOCE 2ZJPE 1M90G 3CCVE 1S72E 1M1KG 1K73G 5GAEG 2QEXE 5JVGE 1VQOE 1YI2E 3OW2E 1Q86G 5MLCH 3DLLE 5JVHE 1K8AG 5AN9B 1K9MG 5GAHG 1VQ8E 5GAGG 1VQKE 1KQSE 2OTJE 3CMEE 3CXCE 3CCJE 3CC2E 1YJNE 3CCUE 1Q7YG 5HL7E 1QVGE 1QVFE 1VQ4E 3CMAE 1VQ6E 2CQLA 1VQ7E 1KD1G 3G4SE 1VQLE 1W2BE 5DM6E 1KC8G 3PIPE 5GADG 1YITE 3CCRE 1YJ9E 1JJ2E 2OTLE 1YHQE
chains in the Genus database with same CATH superfamily
2OYBO 3G6EE 4UY8G 2OL7A 4WFBE 3CCSE 3CPWE 4IO9E 1VQME 2ZJRE 3CF5E 1Q81G 3CCME 1RL6A 3CCEE 5DM7E 1NJIG 4WCEE 3CCLE 3CCQE 3CD6E 1FJ1E 5B3MO 5B11O 2OY5O 4WF9E 4WFAE 2I5VO 1VQ9E 1VQ5E 4U67E 3I56E 1VQNE 3CC4E 3PIOE 3G71E 5H1SI 3EC5A 2ZJQE 1OSPO 1YJWE 2HKDA 2QA4E 4IOAE 1VQPE 3I55E 1Q82G 3IGEA 4WFNE 1N8RG 2PI3O 2AF5A 3CC7E 1YIJE 3AUMO 3J7ZG 4IOCE 2ZJPE 2FKJA 1M90G 3CCVE 1S72E 1M1KG 1K73G 5GAEG 2QEXE 5B10O 5JVGE 1VQOE 1YI2E 3OW2E 5B2AO 1Q86G 2I5ZO 2OY1O 5MLCH 3DLLE 5JVHE 1K8AG 5AN9B 1K9MG 5GAHG 3CKGA 1VQ8E 2FKGA 5GAGG 1VQKE 1KQSE 2OTJE 3CMEE 3IG9A 3CXCE 3CCJE 2OL8O 2OY8A 3CC2E 1YJNE 3CCUE 1Q7YG 5HL7E 2G8CO 1QVGE 1QVFE 2OY7A 1VQ4E 3CKFA 3CMAE 1VQ6E 2CQLA 1VQ7E 1KD1G 3G4SE 1RJLC 1VQLE 1W2BE 5DM6E 1KC8G 3PIPE 2OL6O 5GADG 1YITE 1P4PA 3CCRE 1YJ9E 1JJ2E 2OTLE 1YHQE
chains in the Genus database with same CATH topology
3G6EE 4UY8G 4WFBE 3CCSE 3CPWE 4IO9E 1VQME 2ZJRE 3CF5E 1Q81G 3CCME 1RL6A 3CCEE 5DM7E 1NJIG 4WCEE 3CCLE 3CCQE 3CD6E 4WF9E 4WFAE 1VQ9E 1VQ5E 4U67E 3I56E 1VQNE 3CC4E 3PIOE 3G71E 5H1SI 2ZJQE 1YJWE 2QA4E 4IOAE 1VQPE 3I55E 1Q82G 4WFNE 1N8RG 3CC7E 1YIJE 3J7ZG 4IOCE 2ZJPE 1M90G 3CCVE 1S72E 1M1KG 1K73G 5GAEG 2QEXE 5JVGE 1VQOE 1YI2E 3OW2E 1Q86G 5MLCH 3DLLE 5JVHE 1K8AG 5AN9B 1K9MG 5GAHG 1VQ8E 5GAGG 1VQKE 1KQSE 2OTJE 3CMEE 3CXCE 3CCJE 3CC2E 1YJNE 3CCUE 1Q7YG 5HL7E 1QVGE 1QVFE 1VQ4E 3CMAE 1VQ6E 2CQLA 1VQ7E 1KD1G 3G4SE 1VQLE 1W2BE 5DM6E 1KC8G 3PIPE 5GADG 1YITE 3CCRE 1YJ9E 1JJ2E 2OTLE 1YHQE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3G6E E;  4UY8 G;  4WFB E;  3CCS E;  3CPW E;  4IO9 E;  1VQM E;  2ZJR E;  3CF5 E;  1Q81 G;  3CCM E;  1RL6 A;  3CCE E;  5DM7 E;  1NJI G;  4WCE E;  3CCL E;  3CCQ E;  3CD6 E;  4WF9 E;  4WFA E;  1VQ9 E;  1VQ5 E;  4U67 E;  3I56 E;  1VQN E;  3CC4 E;  3PIO E;  3G71 E;  5H1S I;  2ZJQ E;  1YJW E;  2QA4 E;  4IOA E;  1VQP E;  3I55 E;  1Q82 G;  4WFN E;  1N8R G;  3CC7 E;  1YIJ E;  3J7Z G;  4IOC E;  2ZJP E;  1M90 G;  3CCV E;  1S72 E;  1M1K G;  1K73 G;  5GAE G;  2QEX E;  5JVG E;  1VQO E;  1YI2 E;  3OW2 E;  1Q86 G;  5MLC H;  3DLL E;  5JVH E;  1K8A G;  5AN9 B;  1K9M G;  5GAH G;  1VQ8 E;  5GAG G;  1VQK E;  1KQS E;  2OTJ E;  3CME E;  3CXC E;  3CCJ E;  3CC2 E;  1YJN E;  3CCU E;  1Q7Y G;  5HL7 E;  1QVG E;  1QVF E;  1VQ4 E;  3CMA E;  1VQ6 E;  2CQL A;  1VQ7 E;  1KD1 G;  3G4S E;  1VQL E;  1W2B E;  5DM6 E;  1KC8 G;  3PIP E;  5GAD G;  1YIT E;  3CCR E;  1YJ9 E;  1JJ2 E;  2OTL E;  1YHQ E; 
#chains in the Genus database with same CATH topology
 2OYB O;  3G6E E;  4UY8 G;  2OL7 A;  4WFB E;  3CCS E;  3CPW E;  4IO9 E;  1VQM E;  2ZJR E;  3CF5 E;  1Q81 G;  3CCM E;  1RL6 A;  3CCE E;  5DM7 E;  1NJI G;  4WCE E;  3CCL E;  3CCQ E;  3CD6 E;  1FJ1 E;  5B3M O;  5B11 O;  2OY5 O;  4WF9 E;  4WFA E;  2I5V O;  1VQ9 E;  1VQ5 E;  4U67 E;  3I56 E;  1VQN E;  3CC4 E;  3PIO E;  3G71 E;  5H1S I;  3EC5 A;  2ZJQ E;  1OSP O;  1YJW E;  2HKD A;  2QA4 E;  4IOA E;  1VQP E;  3I55 E;  1Q82 G;  3IGE A;  4WFN E;  1N8R G;  2PI3 O;  2AF5 A;  3CC7 E;  1YIJ E;  3AUM O;  3J7Z G;  4IOC E;  2ZJP E;  2FKJ A;  1M90 G;  3CCV E;  1S72 E;  1M1K G;  1K73 G;  5GAE G;  2QEX E;  5B10 O;  5JVG E;  1VQO E;  1YI2 E;  3OW2 E;  5B2A O;  1Q86 G;  2I5Z O;  2OY1 O;  5MLC H;  3DLL E;  5JVH E;  1K8A G;  5AN9 B;  1K9M G;  5GAH G;  3CKG A;  1VQ8 E;  2FKG A;  5GAG G;  1VQK E;  1KQS E;  2OTJ E;  3CME E;  3IG9 A;  3CXC E;  3CCJ E;  2OL8 O;  2OY8 A;  3CC2 E;  1YJN E;  3CCU E;  1Q7Y G;  5HL7 E;  2G8C O;  1QVG E;  1QVF E;  2OY7 A;  1VQ4 E;  3CKF A;  3CMA E;  1VQ6 E;  2CQL A;  1VQ7 E;  1KD1 G;  3G4S E;  1RJL C;  1VQL E;  1W2B E;  5DM6 E;  1KC8 G;  3PIP E;  2OL6 O;  5GAD G;  1YIT E;  1P4P A;  3CCR E;  1YJ9 E;  1JJ2 E;  2OTL E;  1YHQ E; 
#chains in the Genus database with same CATH homology
 3G6E E;  4UY8 G;  4WFB E;  3CCS E;  3CPW E;  4IO9 E;  1VQM E;  2ZJR E;  3CF5 E;  1Q81 G;  3CCM E;  1RL6 A;  3CCE E;  5DM7 E;  1NJI G;  4WCE E;  3CCL E;  3CCQ E;  3CD6 E;  4WF9 E;  4WFA E;  1VQ9 E;  1VQ5 E;  4U67 E;  3I56 E;  1VQN E;  3CC4 E;  3PIO E;  3G71 E;  5H1S I;  2ZJQ E;  1YJW E;  2QA4 E;  4IOA E;  1VQP E;  3I55 E;  1Q82 G;  4WFN E;  1N8R G;  3CC7 E;  1YIJ E;  3J7Z G;  4IOC E;  2ZJP E;  1M90 G;  3CCV E;  1S72 E;  1M1K G;  1K73 G;  5GAE G;  2QEX E;  5JVG E;  1VQO E;  1YI2 E;  3OW2 E;  1Q86 G;  5MLC H;  3DLL E;  5JVH E;  1K8A G;  5AN9 B;  1K9M G;  5GAH G;  1VQ8 E;  5GAG G;  1VQK E;  1KQS E;  2OTJ E;  3CME E;  3CXC E;  3CCJ E;  3CC2 E;  1YJN E;  3CCU E;  1Q7Y G;  5HL7 E;  1QVG E;  1QVF E;  1VQ4 E;  3CMA E;  1VQ6 E;  2CQL A;  1VQ7 E;  1KD1 G;  3G4S E;  1VQL E;  1W2B E;  5DM6 E;  1KC8 G;  3PIP E;  5GAD G;  1YIT E;  3CCR E;  1YJ9 E;  1JJ2 E;  2OTL E;  1YHQ E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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