1YJ9E

Crystal structure of the mutant 50s ribosomal subunit of haloarcula marismortui containing a three residue deletion in l22
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 36
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yj9E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yj9E01
5GAHG 1YHQE 5GADG 5GAGG 1K8AG 3G4SE 3CCQE 1YI2E 3G71E 1YJWE 1JJ2E 3CD6E 1VQ6E 1KC8G 5DM7E 3CPWE 2ZJPE 1Q81G 4WFBE 3I56E 1Q82G 1VQME 1Q7YG 4IOCE 2ZJQE 4WFAE 1RL6A 1QVFE 2QA4E 3CCEE 1YITE 1K73G 4UY8G 4U67E 3CF5E 2ZJRE 1K9MG 1VQKE 1YJNE 1N8RG 2OTJE 4IOAE 3CCUE 1QVGE 2CQLA 5AN9B 4WF9E 3DLLE 1KQSE 1VQPE 1VQ7E 3PIOE 2QEXE 1VQNE 1VQOE 1KD1G 3CCRE 5JVGE 4IO9E 1YIJE 1NJIG 3J7ZG 3CMEE 1S72E 3CC4E 5GAEG 3CXCE 3CCLE 3G6EE 1YJ9E 1VQLE 4WFNE 3CC7E 3CCJE 1VQ8E 1VQ9E 5H1SI 1M1KG 3CC2E 5JVHE 1VQ5E 5MLCH 5DM6E 1Q86G 5HL7E 3CMAE 1W2BE 3PIPE 3CCVE 1M90G 1VQ4E 3CCSE 2OTLE 4WCEE 3CCME 3I55E 3OW2E
chains in the Genus database with same CATH superfamily
5GAHG 2I5ZO 1YHQE 5GADG 5GAGG 1P4PA 2OY1O 1K8AG 3G4SE 3CCQE 3EC5A 1YI2E 3G71E 1YJWE 2OL7A 1JJ2E 3IGEA 3CD6E 1VQ6E 1KC8G 5DM7E 3CPWE 1OSPO 5B10O 2ZJPE 1Q81G 1FJ1E 4WFBE 2FKGA 3I56E 1Q82G 1VQME 1Q7YG 4IOCE 2ZJQE 5B2AO 2OY8A 4WFAE 1RL6A 3CKFA 1QVFE 2QA4E 3CCEE 1YITE 2I5VO 2OY5O 1K73G 4UY8G 4U67E 3CF5E 2G8CO 2ZJRE 1K9MG 1VQKE 3CKGA 1RJLC 1YJNE 1N8RG 2OTJE 4IOAE 3CCUE 1QVGE 2CQLA 5AN9B 4WF9E 5B3MO 3DLLE 1KQSE 1VQPE 1VQ7E 3PIOE 2QEXE 1VQNE 1VQOE 1KD1G 3CCRE 5JVGE 4IO9E 1YIJE 1NJIG 3J7ZG 3CMEE 1S72E 3CC4E 5GAEG 3CXCE 3CCLE 2AF5A 2OL6O 3G6EE 1YJ9E 1VQLE 4WFNE 3CC7E 3CCJE 1VQ8E 1VQ9E 2FKJA 5H1SI 1M1KG 3CC2E 5JVHE 1VQ5E 5MLCH 2OL8O 5DM6E 2HKDA 2PI3O 3IG9A 1Q86G 2OY7A 5HL7E 3CMAE 3AUMO 1W2BE 3PIPE 3CCVE 1M90G 1VQ4E 3CCSE 2OTLE 4WCEE 3CCME 3I55E 2OYBO 3OW2E 5B11O
chains in the Genus database with same CATH topology
5GAHG 1YHQE 5GADG 5GAGG 1K8AG 3G4SE 3CCQE 1YI2E 3G71E 1YJWE 1JJ2E 3CD6E 1VQ6E 1KC8G 5DM7E 3CPWE 2ZJPE 1Q81G 4WFBE 3I56E 1Q82G 1VQME 1Q7YG 4IOCE 2ZJQE 4WFAE 1RL6A 1QVFE 2QA4E 3CCEE 1YITE 1K73G 4UY8G 4U67E 3CF5E 2ZJRE 1K9MG 1VQKE 1YJNE 1N8RG 2OTJE 4IOAE 3CCUE 1QVGE 2CQLA 5AN9B 4WF9E 3DLLE 1KQSE 1VQPE 1VQ7E 3PIOE 2QEXE 1VQNE 1VQOE 1KD1G 3CCRE 5JVGE 4IO9E 1YIJE 1NJIG 3J7ZG 3CMEE 1S72E 3CC4E 5GAEG 3CXCE 3CCLE 3G6EE 1YJ9E 1VQLE 4WFNE 3CC7E 3CCJE 1VQ8E 1VQ9E 5H1SI 1M1KG 3CC2E 5JVHE 1VQ5E 5MLCH 5DM6E 1Q86G 5HL7E 3CMAE 1W2BE 3PIPE 3CCVE 1M90G 1VQ4E 3CCSE 2OTLE 4WCEE 3CCME 3I55E 3OW2E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GAH G;  1YHQ E;  5GAD G;  5GAG G;  1K8A G;  3G4S E;  3CCQ E;  1YI2 E;  3G71 E;  1YJW E;  1JJ2 E;  3CD6 E;  1VQ6 E;  1KC8 G;  5DM7 E;  3CPW E;  2ZJP E;  1Q81 G;  4WFB E;  3I56 E;  1Q82 G;  1VQM E;  1Q7Y G;  4IOC E;  2ZJQ E;  4WFA E;  1RL6 A;  1QVF E;  2QA4 E;  3CCE E;  1YIT E;  1K73 G;  4UY8 G;  4U67 E;  3CF5 E;  2ZJR E;  1K9M G;  1VQK E;  1YJN E;  1N8R G;  2OTJ E;  4IOA E;  3CCU E;  1QVG E;  2CQL A;  5AN9 B;  4WF9 E;  3DLL E;  1KQS E;  1VQP E;  1VQ7 E;  3PIO E;  2QEX E;  1VQN E;  1VQO E;  1KD1 G;  3CCR E;  5JVG E;  4IO9 E;  1YIJ E;  1NJI G;  3J7Z G;  3CME E;  1S72 E;  3CC4 E;  5GAE G;  3CXC E;  3CCL E;  3G6E E;  1YJ9 E;  1VQL E;  4WFN E;  3CC7 E;  3CCJ E;  1VQ8 E;  1VQ9 E;  5H1S I;  1M1K G;  3CC2 E;  5JVH E;  1VQ5 E;  5MLC H;  5DM6 E;  1Q86 G;  5HL7 E;  3CMA E;  1W2B E;  3PIP E;  3CCV E;  1M90 G;  1VQ4 E;  3CCS E;  2OTL E;  4WCE E;  3CCM E;  3I55 E;  3OW2 E; 
#chains in the Genus database with same CATH topology
 5GAH G;  2I5Z O;  1YHQ E;  5GAD G;  5GAG G;  1P4P A;  2OY1 O;  1K8A G;  3G4S E;  3CCQ E;  3EC5 A;  1YI2 E;  3G71 E;  1YJW E;  2OL7 A;  1JJ2 E;  3IGE A;  3CD6 E;  1VQ6 E;  1KC8 G;  5DM7 E;  3CPW E;  1OSP O;  5B10 O;  2ZJP E;  1Q81 G;  1FJ1 E;  4WFB E;  2FKG A;  3I56 E;  1Q82 G;  1VQM E;  1Q7Y G;  4IOC E;  2ZJQ E;  5B2A O;  2OY8 A;  4WFA E;  1RL6 A;  3CKF A;  1QVF E;  2QA4 E;  3CCE E;  1YIT E;  2I5V O;  2OY5 O;  1K73 G;  4UY8 G;  4U67 E;  3CF5 E;  2G8C O;  2ZJR E;  1K9M G;  1VQK E;  3CKG A;  1RJL C;  1YJN E;  1N8R G;  2OTJ E;  4IOA E;  3CCU E;  1QVG E;  2CQL A;  5AN9 B;  4WF9 E;  5B3M O;  3DLL E;  1KQS E;  1VQP E;  1VQ7 E;  3PIO E;  2QEX E;  1VQN E;  1VQO E;  1KD1 G;  3CCR E;  5JVG E;  4IO9 E;  1YIJ E;  1NJI G;  3J7Z G;  3CME E;  1S72 E;  3CC4 E;  5GAE G;  3CXC E;  3CCL E;  2AF5 A;  2OL6 O;  3G6E E;  1YJ9 E;  1VQL E;  4WFN E;  3CC7 E;  3CCJ E;  1VQ8 E;  1VQ9 E;  2FKJ A;  5H1S I;  1M1K G;  3CC2 E;  5JVH E;  1VQ5 E;  5MLC H;  2OL8 O;  5DM6 E;  2HKD A;  2PI3 O;  3IG9 A;  1Q86 G;  2OY7 A;  5HL7 E;  3CMA E;  3AUM O;  1W2B E;  3PIP E;  3CCV E;  1M90 G;  1VQ4 E;  3CCS E;  2OTL E;  4WCE E;  3CCM E;  3I55 E;  2OYB O;  3OW2 E;  5B11 O; 
#chains in the Genus database with same CATH homology
 5GAH G;  1YHQ E;  5GAD G;  5GAG G;  1K8A G;  3G4S E;  3CCQ E;  1YI2 E;  3G71 E;  1YJW E;  1JJ2 E;  3CD6 E;  1VQ6 E;  1KC8 G;  5DM7 E;  3CPW E;  2ZJP E;  1Q81 G;  4WFB E;  3I56 E;  1Q82 G;  1VQM E;  1Q7Y G;  4IOC E;  2ZJQ E;  4WFA E;  1RL6 A;  1QVF E;  2QA4 E;  3CCE E;  1YIT E;  1K73 G;  4UY8 G;  4U67 E;  3CF5 E;  2ZJR E;  1K9M G;  1VQK E;  1YJN E;  1N8R G;  2OTJ E;  4IOA E;  3CCU E;  1QVG E;  2CQL A;  5AN9 B;  4WF9 E;  3DLL E;  1KQS E;  1VQP E;  1VQ7 E;  3PIO E;  2QEX E;  1VQN E;  1VQO E;  1KD1 G;  3CCR E;  5JVG E;  4IO9 E;  1YIJ E;  1NJI G;  3J7Z G;  3CME E;  1S72 E;  3CC4 E;  5GAE G;  3CXC E;  3CCL E;  3G6E E;  1YJ9 E;  1VQL E;  4WFN E;  3CC7 E;  3CCJ E;  1VQ8 E;  1VQ9 E;  5H1S I;  1M1K G;  3CC2 E;  5JVH E;  1VQ5 E;  5MLC H;  5DM6 E;  1Q86 G;  5HL7 E;  3CMA E;  1W2B E;  3PIP E;  3CCV E;  1M90 G;  1VQ4 E;  3CCS E;  2OTL E;  4WCE E;  3CCM E;  3I55 E;  3OW2 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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