1YJNE

Crystal structure of clindamycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2005-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yjnE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yjnE01
1YJ9E 4WFBE 5GADG 1RL6A 1QVFE 3CMAE 5DM6E 1VQ9E 1YITE 5HL7E 4IOAE 3CCUE 3CCLE 1VQLE 1YIJE 3PIOE 5JVHE 1K9MG 4WCEE 1KC8G 1W2BE 3DLLE 4IO9E 1VQ7E 1KQSE 2OTLE 2QEXE 3CCQE 1S72E 1QVGE 3CCME 3PIPE 1VQ6E 1YJWE 3CD6E 3I55E 1VQOE 5JVGE 1YHQE 1KD1G 3CPWE 5GAGG 1VQME 1VQPE 3CCJE 1Q7YG 3G6EE 2ZJPE 1M90G 3CMEE 1Q86G 1VQ8E 3OW2E 5GAEG 4WFAE 3CF5E 5AN9B 1YI2E 4IOCE 4U67E 3CC7E 1K8AG 1M1KG 1VQKE 3CC4E 4WFNE 2QA4E 2CQLA 3G4SE 1JJ2E 3CCVE 5GAHG 1VQ4E 3CCSE 1Q81G 1K73G 3CCEE 2OTJE 4WF9E 2ZJQE 5H1SI 3I56E 3G71E 1Q82G 5MLCH 2ZJRE 1N8RG 3CC2E 1NJIG 4UY8G 3J7ZG 1VQ5E 3CXCE 5DM7E 1YJNE 1VQNE 3CCRE
chains in the Genus database with same CATH superfamily
1YJ9E 5B2AO 4WFBE 5GADG 1RL6A 1QVFE 3CMAE 5DM6E 2OL6O 1VQ9E 2OY1O 1YITE 5HL7E 4IOAE 3CCUE 3CCLE 1VQLE 1FJ1E 2OYBO 1YIJE 3PIOE 5JVHE 1K9MG 4WCEE 1KC8G 1W2BE 3DLLE 4IO9E 1VQ7E 1KQSE 2OTLE 2QEXE 2AF5A 3CCQE 3CKFA 1S72E 1QVGE 3CCME 1P4PA 3AUMO 3PIPE 2HKDA 1VQ6E 2OY8A 1YJWE 3CD6E 3I55E 3CKGA 2OY7A 1VQOE 5JVGE 1YHQE 1KD1G 5B3MO 3CPWE 5GAGG 1VQME 1VQPE 3CCJE 1Q7YG 3G6EE 2ZJPE 1M90G 3CMEE 1Q86G 1VQ8E 3OW2E 5GAEG 4WFAE 3CF5E 5AN9B 1RJLC 5B11O 1YI2E 4IOCE 4U67E 3CC7E 2PI3O 1K8AG 1M1KG 1VQKE 3CC4E 2OL8O 4WFNE 2QA4E 2CQLA 3G4SE 1JJ2E 3CCVE 5GAHG 1VQ4E 3CCSE 5B10O 1Q81G 3CCEE 2FKGA 1K73G 2I5ZO 2OTJE 1OSPO 4WF9E 2ZJQE 5H1SI 3I56E 3IGEA 3G71E 2OL7A 1Q82G 2I5VO 3IG9A 5MLCH 2ZJRE 1N8RG 3CC2E 2OY5O 1NJIG 4UY8G 3J7ZG 2G8CO 1VQ5E 3CXCE 3EC5A 5DM7E 1YJNE 2FKJA 1VQNE 3CCRE
chains in the Genus database with same CATH topology
1YJ9E 4WFBE 5GADG 1RL6A 1QVFE 3CMAE 5DM6E 1VQ9E 1YITE 5HL7E 4IOAE 3CCUE 3CCLE 1VQLE 1YIJE 3PIOE 5JVHE 1K9MG 4WCEE 1KC8G 1W2BE 3DLLE 4IO9E 1VQ7E 1KQSE 2OTLE 2QEXE 3CCQE 1S72E 1QVGE 3CCME 3PIPE 1VQ6E 1YJWE 3CD6E 3I55E 1VQOE 5JVGE 1YHQE 1KD1G 3CPWE 5GAGG 1VQME 1VQPE 3CCJE 1Q7YG 3G6EE 2ZJPE 1M90G 3CMEE 1Q86G 1VQ8E 3OW2E 5GAEG 4WFAE 3CF5E 5AN9B 1YI2E 4IOCE 4U67E 3CC7E 1K8AG 1M1KG 1VQKE 3CC4E 4WFNE 2QA4E 2CQLA 3G4SE 1JJ2E 3CCVE 5GAHG 1VQ4E 3CCSE 1Q81G 1K73G 3CCEE 2OTJE 4WF9E 2ZJQE 5H1SI 3I56E 3G71E 1Q82G 5MLCH 2ZJRE 1N8RG 3CC2E 1NJIG 4UY8G 3J7ZG 1VQ5E 3CXCE 5DM7E 1YJNE 1VQNE 3CCRE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YJ9 E;  4WFB E;  5GAD G;  1RL6 A;  1QVF E;  3CMA E;  5DM6 E;  1VQ9 E;  1YIT E;  5HL7 E;  4IOA E;  3CCU E;  3CCL E;  1VQL E;  1YIJ E;  3PIO E;  5JVH E;  1K9M G;  4WCE E;  1KC8 G;  1W2B E;  3DLL E;  4IO9 E;  1VQ7 E;  1KQS E;  2OTL E;  2QEX E;  3CCQ E;  1S72 E;  1QVG E;  3CCM E;  3PIP E;  1VQ6 E;  1YJW E;  3CD6 E;  3I55 E;  1VQO E;  5JVG E;  1YHQ E;  1KD1 G;  3CPW E;  5GAG G;  1VQM E;  1VQP E;  3CCJ E;  1Q7Y G;  3G6E E;  2ZJP E;  1M90 G;  3CME E;  1Q86 G;  1VQ8 E;  3OW2 E;  5GAE G;  4WFA E;  3CF5 E;  5AN9 B;  1YI2 E;  4IOC E;  4U67 E;  3CC7 E;  1K8A G;  1M1K G;  1VQK E;  3CC4 E;  4WFN E;  2QA4 E;  2CQL A;  3G4S E;  1JJ2 E;  3CCV E;  5GAH G;  1VQ4 E;  3CCS E;  1Q81 G;  1K73 G;  3CCE E;  2OTJ E;  4WF9 E;  2ZJQ E;  5H1S I;  3I56 E;  3G71 E;  1Q82 G;  5MLC H;  2ZJR E;  1N8R G;  3CC2 E;  1NJI G;  4UY8 G;  3J7Z G;  1VQ5 E;  3CXC E;  5DM7 E;  1YJN E;  1VQN E;  3CCR E; 
#chains in the Genus database with same CATH topology
 1YJ9 E;  5B2A O;  4WFB E;  5GAD G;  1RL6 A;  1QVF E;  3CMA E;  5DM6 E;  2OL6 O;  1VQ9 E;  2OY1 O;  1YIT E;  5HL7 E;  4IOA E;  3CCU E;  3CCL E;  1VQL E;  1FJ1 E;  2OYB O;  1YIJ E;  3PIO E;  5JVH E;  1K9M G;  4WCE E;  1KC8 G;  1W2B E;  3DLL E;  4IO9 E;  1VQ7 E;  1KQS E;  2OTL E;  2QEX E;  2AF5 A;  3CCQ E;  3CKF A;  1S72 E;  1QVG E;  3CCM E;  1P4P A;  3AUM O;  3PIP E;  2HKD A;  1VQ6 E;  2OY8 A;  1YJW E;  3CD6 E;  3I55 E;  3CKG A;  2OY7 A;  1VQO E;  5JVG E;  1YHQ E;  1KD1 G;  5B3M O;  3CPW E;  5GAG G;  1VQM E;  1VQP E;  3CCJ E;  1Q7Y G;  3G6E E;  2ZJP E;  1M90 G;  3CME E;  1Q86 G;  1VQ8 E;  3OW2 E;  5GAE G;  4WFA E;  3CF5 E;  5AN9 B;  1RJL C;  5B11 O;  1YI2 E;  4IOC E;  4U67 E;  3CC7 E;  2PI3 O;  1K8A G;  1M1K G;  1VQK E;  3CC4 E;  2OL8 O;  4WFN E;  2QA4 E;  2CQL A;  3G4S E;  1JJ2 E;  3CCV E;  5GAH G;  1VQ4 E;  3CCS E;  5B10 O;  1Q81 G;  3CCE E;  2FKG A;  1K73 G;  2I5Z O;  2OTJ E;  1OSP O;  4WF9 E;  2ZJQ E;  5H1S I;  3I56 E;  3IGE A;  3G71 E;  2OL7 A;  1Q82 G;  2I5V O;  3IG9 A;  5MLC H;  2ZJR E;  1N8R G;  3CC2 E;  2OY5 O;  1NJI G;  4UY8 G;  3J7Z G;  2G8C O;  1VQ5 E;  3CXC E;  3EC5 A;  5DM7 E;  1YJN E;  2FKJ A;  1VQN E;  3CCR E; 
#chains in the Genus database with same CATH homology
 1YJ9 E;  4WFB E;  5GAD G;  1RL6 A;  1QVF E;  3CMA E;  5DM6 E;  1VQ9 E;  1YIT E;  5HL7 E;  4IOA E;  3CCU E;  3CCL E;  1VQL E;  1YIJ E;  3PIO E;  5JVH E;  1K9M G;  4WCE E;  1KC8 G;  1W2B E;  3DLL E;  4IO9 E;  1VQ7 E;  1KQS E;  2OTL E;  2QEX E;  3CCQ E;  1S72 E;  1QVG E;  3CCM E;  3PIP E;  1VQ6 E;  1YJW E;  3CD6 E;  3I55 E;  1VQO E;  5JVG E;  1YHQ E;  1KD1 G;  3CPW E;  5GAG G;  1VQM E;  1VQP E;  3CCJ E;  1Q7Y G;  3G6E E;  2ZJP E;  1M90 G;  3CME E;  1Q86 G;  1VQ8 E;  3OW2 E;  5GAE G;  4WFA E;  3CF5 E;  5AN9 B;  1YI2 E;  4IOC E;  4U67 E;  3CC7 E;  1K8A G;  1M1K G;  1VQK E;  3CC4 E;  4WFN E;  2QA4 E;  2CQL A;  3G4S E;  1JJ2 E;  3CCV E;  5GAH G;  1VQ4 E;  3CCS E;  1Q81 G;  1K73 G;  3CCE E;  2OTJ E;  4WF9 E;  2ZJQ E;  5H1S I;  3I56 E;  3G71 E;  1Q82 G;  5MLC H;  2ZJR E;  1N8R G;  3CC2 E;  1NJI G;  4UY8 G;  3J7Z G;  1VQ5 E;  3CXC E;  5DM7 E;  1YJN E;  1VQN E;  3CCR E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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