1YIJE

Crystal structure of telithromycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2005-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yijE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yijE01
2OTJE 2ZJRE 4IO9E 4WFNE 3CCJE 1YHQE 3CCRE 3CCME 1W2BE 1Q86G 1K9MG 3CF5E 1Q7YG 4IOCE 5GADG 2QA4E 1JJ2E 4WFBE 1Q81G 5H1SI 1VQ8E 1Q82G 5GAEG 2ZJPE 1KC8G 1VQ9E 1VQPE 4WCEE 4IOAE 1YJWE 3J7ZG 1N8RG 3CC2E 1S72E 1KD1G 1K73G 5JVGE 1QVFE 1QVGE 3CXCE 3CD6E 3CCLE 3G4SE 1VQME 3G6EE 1VQNE 3PIPE 3I56E 1YI2E 1VQ6E 3CC7E 1NJIG 3CPWE 5DM6E 3CCUE 4UY8G 4WF9E 5HL7E 1VQ7E 3DLLE 5GAHG 1YITE 3CCSE 3PIOE 2ZJQE 1YIJE 3I55E 4WFAE 2QEXE 3G71E 3CCVE 5MLCH 1VQOE 4U67E 3CCEE 3OW2E 2OTLE 1RL6A 3CMEE 1M90G 3CCQE 1K8AG 1VQ5E 1YJ9E 5AN9B 1KQSE 3CC4E 1VQLE 1VQ4E 1M1KG 3CMAE 1VQKE 5JVHE 5DM7E 5GAGG 1YJNE 2CQLA
chains in the Genus database with same CATH superfamily
2I5VO 2OL6O 2OTJE 2ZJRE 2HKDA 3IG9A 4IO9E 4WFNE 3CCJE 3IGEA 1YHQE 3CCRE 3CCME 1W2BE 1Q86G 1K9MG 3CF5E 1Q7YG 4IOCE 5GADG 2QA4E 1JJ2E 2OY7A 4WFBE 1Q81G 5H1SI 1VQ8E 2OL7A 1Q82G 5GAEG 2ZJPE 1KC8G 1VQ9E 2I5ZO 3AUMO 1VQPE 1RJLC 5B2AO 4WCEE 4IOAE 1YJWE 1OSPO 3J7ZG 1N8RG 3CC2E 1S72E 1KD1G 1K73G 1P4PA 5JVGE 1QVFE 1QVGE 3CXCE 3CD6E 3CCLE 5B10O 2OY1O 3G4SE 1VQME 1VQNE 3PIPE 5B11O 3I56E 2OY8A 2OY5O 1YI2E 1VQ6E 3CC7E 1NJIG 3CPWE 5DM6E 3CCUE 4UY8G 4WF9E 5HL7E 1VQ7E 3DLLE 5GAHG 1YITE 3CCSE 2OL8O 2G8CO 3PIOE 2AF5A 2ZJQE 1YIJE 3I55E 2OYBO 3EC5A 4WFAE 3CKFA 2QEXE 3G71E 3CCVE 5MLCH 1VQOE 4U67E 3CCEE 3OW2E 2OTLE 1RL6A 3CMEE 1M90G 3CCQE 1K8AG 1VQ5E 1YJ9E 5B3MO 5AN9B 1KQSE 3CC4E 2PI3O 2FKJA 2FKGA 1VQLE 1VQ4E 1M1KG 3CMAE 1VQKE 3CKGA 1FJ1E 5JVHE 1YJNE 5DM7E 5GAGG 3G6EE 2CQLA
chains in the Genus database with same CATH topology
2OTJE 2ZJRE 4IO9E 4WFNE 3CCJE 1YHQE 3CCRE 3CCME 1W2BE 1Q86G 1K9MG 3CF5E 1Q7YG 4IOCE 5GADG 2QA4E 1JJ2E 4WFBE 1Q81G 5H1SI 1VQ8E 1Q82G 5GAEG 2ZJPE 1KC8G 1VQ9E 1VQPE 4WCEE 4IOAE 1YJWE 3J7ZG 1N8RG 3CC2E 1S72E 1KD1G 1K73G 5JVGE 1QVFE 1QVGE 3CXCE 3CD6E 3CCLE 3G4SE 1VQME 3G6EE 1VQNE 3PIPE 3I56E 1YI2E 1VQ6E 3CC7E 1NJIG 3CPWE 5DM6E 3CCUE 4UY8G 4WF9E 5HL7E 1VQ7E 3DLLE 5GAHG 1YITE 3CCSE 3PIOE 2ZJQE 1YIJE 3I55E 4WFAE 2QEXE 3G71E 3CCVE 5MLCH 1VQOE 4U67E 3CCEE 3OW2E 2OTLE 1RL6A 3CMEE 1M90G 3CCQE 1K8AG 1VQ5E 1YJ9E 5AN9B 1KQSE 3CC4E 1VQLE 1VQ4E 1M1KG 3CMAE 1VQKE 5JVHE 5DM7E 5GAGG 1YJNE 2CQLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OTJ E;  2ZJR E;  4IO9 E;  4WFN E;  3CCJ E;  1YHQ E;  3CCR E;  3CCM E;  1W2B E;  1Q86 G;  1K9M G;  3CF5 E;  1Q7Y G;  4IOC E;  5GAD G;  2QA4 E;  1JJ2 E;  4WFB E;  1Q81 G;  5H1S I;  1VQ8 E;  1Q82 G;  5GAE G;  2ZJP E;  1KC8 G;  1VQ9 E;  1VQP E;  4WCE E;  4IOA E;  1YJW E;  3J7Z G;  1N8R G;  3CC2 E;  1S72 E;  1KD1 G;  1K73 G;  5JVG E;  1QVF E;  1QVG E;  3CXC E;  3CD6 E;  3CCL E;  3G4S E;  1VQM E;  3G6E E;  1VQN E;  3PIP E;  3I56 E;  1YI2 E;  1VQ6 E;  3CC7 E;  1NJI G;  3CPW E;  5DM6 E;  3CCU E;  4UY8 G;  4WF9 E;  5HL7 E;  1VQ7 E;  3DLL E;  5GAH G;  1YIT E;  3CCS E;  3PIO E;  2ZJQ E;  1YIJ E;  3I55 E;  4WFA E;  2QEX E;  3G71 E;  3CCV E;  5MLC H;  1VQO E;  4U67 E;  3CCE E;  3OW2 E;  2OTL E;  1RL6 A;  3CME E;  1M90 G;  3CCQ E;  1K8A G;  1VQ5 E;  1YJ9 E;  5AN9 B;  1KQS E;  3CC4 E;  1VQL E;  1VQ4 E;  1M1K G;  3CMA E;  1VQK E;  5JVH E;  5DM7 E;  5GAG G;  1YJN E;  2CQL A; 
#chains in the Genus database with same CATH topology
 2I5V O;  2OL6 O;  2OTJ E;  2ZJR E;  2HKD A;  3IG9 A;  4IO9 E;  4WFN E;  3CCJ E;  3IGE A;  1YHQ E;  3CCR E;  3CCM E;  1W2B E;  1Q86 G;  1K9M G;  3CF5 E;  1Q7Y G;  4IOC E;  5GAD G;  2QA4 E;  1JJ2 E;  2OY7 A;  4WFB E;  1Q81 G;  5H1S I;  1VQ8 E;  2OL7 A;  1Q82 G;  5GAE G;  2ZJP E;  1KC8 G;  1VQ9 E;  2I5Z O;  3AUM O;  1VQP E;  1RJL C;  5B2A O;  4WCE E;  4IOA E;  1YJW E;  1OSP O;  3J7Z G;  1N8R G;  3CC2 E;  1S72 E;  1KD1 G;  1K73 G;  1P4P A;  5JVG E;  1QVF E;  1QVG E;  3CXC E;  3CD6 E;  3CCL E;  5B10 O;  2OY1 O;  3G4S E;  1VQM E;  1VQN E;  3PIP E;  5B11 O;  3I56 E;  2OY8 A;  2OY5 O;  1YI2 E;  1VQ6 E;  3CC7 E;  1NJI G;  3CPW E;  5DM6 E;  3CCU E;  4UY8 G;  4WF9 E;  5HL7 E;  1VQ7 E;  3DLL E;  5GAH G;  1YIT E;  3CCS E;  2OL8 O;  2G8C O;  3PIO E;  2AF5 A;  2ZJQ E;  1YIJ E;  3I55 E;  2OYB O;  3EC5 A;  4WFA E;  3CKF A;  2QEX E;  3G71 E;  3CCV E;  5MLC H;  1VQO E;  4U67 E;  3CCE E;  3OW2 E;  2OTL E;  1RL6 A;  3CME E;  1M90 G;  3CCQ E;  1K8A G;  1VQ5 E;  1YJ9 E;  5B3M O;  5AN9 B;  1KQS E;  3CC4 E;  2PI3 O;  2FKJ A;  2FKG A;  1VQL E;  1VQ4 E;  1M1K G;  3CMA E;  1VQK E;  3CKG A;  1FJ1 E;  5JVH E;  1YJN E;  5DM7 E;  5GAG G;  3G6E E;  2CQL A; 
#chains in the Genus database with same CATH homology
 2OTJ E;  2ZJR E;  4IO9 E;  4WFN E;  3CCJ E;  1YHQ E;  3CCR E;  3CCM E;  1W2B E;  1Q86 G;  1K9M G;  3CF5 E;  1Q7Y G;  4IOC E;  5GAD G;  2QA4 E;  1JJ2 E;  4WFB E;  1Q81 G;  5H1S I;  1VQ8 E;  1Q82 G;  5GAE G;  2ZJP E;  1KC8 G;  1VQ9 E;  1VQP E;  4WCE E;  4IOA E;  1YJW E;  3J7Z G;  1N8R G;  3CC2 E;  1S72 E;  1KD1 G;  1K73 G;  5JVG E;  1QVF E;  1QVG E;  3CXC E;  3CD6 E;  3CCL E;  3G4S E;  1VQM E;  3G6E E;  1VQN E;  3PIP E;  3I56 E;  1YI2 E;  1VQ6 E;  3CC7 E;  1NJI G;  3CPW E;  5DM6 E;  3CCU E;  4UY8 G;  4WF9 E;  5HL7 E;  1VQ7 E;  3DLL E;  5GAH G;  1YIT E;  3CCS E;  3PIO E;  2ZJQ E;  1YIJ E;  3I55 E;  4WFA E;  2QEX E;  3G71 E;  3CCV E;  5MLC H;  1VQO E;  4U67 E;  3CCE E;  3OW2 E;  2OTL E;  1RL6 A;  3CME E;  1M90 G;  3CCQ E;  1K8A G;  1VQ5 E;  1YJ9 E;  5AN9 B;  1KQS E;  3CC4 E;  1VQL E;  1VQ4 E;  1M1K G;  3CMA E;  1VQK E;  5JVH E;  5DM7 E;  5GAG G;  1YJN E;  2CQL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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