1YJNE

Crystal structure of clindamycin bound to the g2099a mutant 50s ribosomal subunit of haloarcula marismortui
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
172
structure length
172
Chain Sequence
PRVELEIPEDVDAEQDHLDITVEGDNGSVTRRLWYPDIDVSVDGDTVVIESDEDNAKTMSTIGTFQSHIENMFHGVTEGWEYGMEVFYSHFPMQVNVEGDEVVIENFLGEKAPRRTTIHGDTDVEIDGEELTVSGPDIEAVGQTAADIEQLTRINDKDVRVFQDGVYITRKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S Ribosomal RNA
total genus 37
structure length 172
sequence length 172
ec nomenclature
pdb deposition date 2005-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yjnE02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 1yjnE01
1W2BE 3PIPE 4U67E 4WCEE 3CCUE 1VQME 5HL7E 2ZJPE 1Q81G 4IOCE 3CCQE 2ZJRE 1VQLE 1VQ7E 2CQLA 5DM6E 3G4SE 2QEXE 1Q86G 3CC2E 3CC7E 1Q7YG 1VQ8E 1S72E 2ZJQE 2OTJE 1KD1G 1K9MG 5GAEG 1KQSE 3OW2E 3CMAE 5H1SI 4WFBE 1K8AG 4WF9E 1QVFE 1KC8G 4WFAE 1YHQE 1M1KG 3CMEE 3I56E 3CCJE 3CPWE 5GAGG 5GADG 1YJNE 1YJ9E 5GAHG 3PIOE 4UY8G 3I55E 1M90G 3CCEE 3CCLE 3CCVE 1YI2E 3CCSE 1VQ6E 1YJWE 3CCRE 1VQKE 1Q82G 1VQNE 4IOAE 1VQPE 3CC4E 3DLLE 2QA4E 1K73G 5JVGE 1N8RG 1VQ5E 1VQ9E 1JJ2E 1YITE 3CF5E 5AN9B 4WFNE 3CXCE 2OTLE 4IO9E 1NJIG 3J7ZG 3G6EE 1QVGE 3CCME 5DM7E 1VQOE 5JVHE 3G71E 1VQ4E 5MLCH 3CD6E 1YIJE 1RL6A
chains in the Genus database with same CATH superfamily
1W2BE 1FJ1E 3PIPE 4U67E 2OY1O 4WCEE 3CCUE 3CKGA 1VQME 5HL7E 2ZJPE 1Q81G 2OL6O 4IOCE 3CCQE 2OY8A 3IG9A 2ZJRE 1VQLE 2HKDA 1VQ7E 2CQLA 5B11O 5DM6E 3G4SE 2QEXE 1Q86G 3CC2E 3CC7E 1Q7YG 1VQ8E 1S72E 2ZJQE 2OTJE 1KD1G 1K9MG 2PI3O 5B10O 5GAEG 1KQSE 3OW2E 3CMAE 5H1SI 2I5ZO 4WFBE 1K8AG 3AUMO 4WF9E 1QVFE 5B2AO 1KC8G 4WFAE 1YHQE 1M1KG 2FKGA 5B3MO 3CMEE 3I56E 3CCJE 3CPWE 3IGEA 5GAGG 2OL8O 5GADG 1YJNE 1YJ9E 5GAHG 3PIOE 4UY8G 3I55E 1M90G 3CCEE 3CCLE 3CCVE 1YI2E 3CCSE 1VQ6E 1YJWE 3CCRE 1RJLC 1VQKE 1P4PA 2OY5O 1Q82G 1VQNE 4IOAE 1VQPE 3CC4E 3DLLE 2OL7A 2QA4E 5JVGE 1K73G 1N8RG 1VQ5E 1VQ9E 1JJ2E 2FKJA 3CKFA 1YITE 2AF5A 2G8CO 3CF5E 2OYBO 5AN9B 4WFNE 3CXCE 2OTLE 4IO9E 3J7ZG 3G6EE 1NJIG 1QVGE 3CCME 1OSPO 5DM7E 1VQOE 5JVHE 2I5VO 3G71E 1VQ4E 5MLCH 3CD6E 1YIJE 1RL6A 3EC5A 2OY7A
chains in the Genus database with same CATH topology
1W2BE 3PIPE 4U67E 4WCEE 3CCUE 1VQME 5HL7E 2ZJPE 1Q81G 4IOCE 3CCQE 2ZJRE 1VQLE 1VQ7E 2CQLA 5DM6E 3G4SE 2QEXE 1Q86G 3CC2E 3CC7E 1Q7YG 1VQ8E 1S72E 2ZJQE 2OTJE 1KD1G 1K9MG 5GAEG 1KQSE 3OW2E 3CMAE 5H1SI 4WFBE 1K8AG 4WF9E 1QVFE 1KC8G 4WFAE 1YHQE 1M1KG 3CMEE 3I56E 3CCJE 3CPWE 5GAGG 5GADG 1YJNE 1YJ9E 5GAHG 3PIOE 4UY8G 3I55E 1M90G 3CCEE 3CCLE 3CCVE 1YI2E 3CCSE 1VQ6E 1YJWE 3CCRE 1VQKE 1Q82G 1VQNE 4IOAE 1VQPE 3CC4E 3DLLE 2QA4E 1K73G 5JVGE 1N8RG 1VQ5E 1VQ9E 1JJ2E 1YITE 3CF5E 5AN9B 4WFNE 3CXCE 2OTLE 4IO9E 1NJIG 3J7ZG 3G6EE 1QVGE 3CCME 5DM7E 1VQOE 5JVHE 3G71E 1VQ4E 5MLCH 3CD6E 1YIJE 1RL6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W2B E;  3PIP E;  4U67 E;  4WCE E;  3CCU E;  1VQM E;  5HL7 E;  2ZJP E;  1Q81 G;  4IOC E;  3CCQ E;  2ZJR E;  1VQL E;  1VQ7 E;  2CQL A;  5DM6 E;  3G4S E;  2QEX E;  1Q86 G;  3CC2 E;  3CC7 E;  1Q7Y G;  1VQ8 E;  1S72 E;  2ZJQ E;  2OTJ E;  1KD1 G;  1K9M G;  5GAE G;  1KQS E;  3OW2 E;  3CMA E;  5H1S I;  4WFB E;  1K8A G;  4WF9 E;  1QVF E;  1KC8 G;  4WFA E;  1YHQ E;  1M1K G;  3CME E;  3I56 E;  3CCJ E;  3CPW E;  5GAG G;  5GAD G;  1YJN E;  1YJ9 E;  5GAH G;  3PIO E;  4UY8 G;  3I55 E;  1M90 G;  3CCE E;  3CCL E;  3CCV E;  1YI2 E;  3CCS E;  1VQ6 E;  1YJW E;  3CCR E;  1VQK E;  1Q82 G;  1VQN E;  4IOA E;  1VQP E;  3CC4 E;  3DLL E;  2QA4 E;  1K73 G;  5JVG E;  1N8R G;  1VQ5 E;  1VQ9 E;  1JJ2 E;  1YIT E;  3CF5 E;  5AN9 B;  4WFN E;  3CXC E;  2OTL E;  4IO9 E;  1NJI G;  3J7Z G;  3G6E E;  1QVG E;  3CCM E;  5DM7 E;  1VQO E;  5JVH E;  3G71 E;  1VQ4 E;  5MLC H;  3CD6 E;  1YIJ E;  1RL6 A; 
#chains in the Genus database with same CATH topology
 1W2B E;  1FJ1 E;  3PIP E;  4U67 E;  2OY1 O;  4WCE E;  3CCU E;  3CKG A;  1VQM E;  5HL7 E;  2ZJP E;  1Q81 G;  2OL6 O;  4IOC E;  3CCQ E;  2OY8 A;  3IG9 A;  2ZJR E;  1VQL E;  2HKD A;  1VQ7 E;  2CQL A;  5B11 O;  5DM6 E;  3G4S E;  2QEX E;  1Q86 G;  3CC2 E;  3CC7 E;  1Q7Y G;  1VQ8 E;  1S72 E;  2ZJQ E;  2OTJ E;  1KD1 G;  1K9M G;  2PI3 O;  5B10 O;  5GAE G;  1KQS E;  3OW2 E;  3CMA E;  5H1S I;  2I5Z O;  4WFB E;  1K8A G;  3AUM O;  4WF9 E;  1QVF E;  5B2A O;  1KC8 G;  4WFA E;  1YHQ E;  1M1K G;  2FKG A;  5B3M O;  3CME E;  3I56 E;  3CCJ E;  3CPW E;  3IGE A;  5GAG G;  2OL8 O;  5GAD G;  1YJN E;  1YJ9 E;  5GAH G;  3PIO E;  4UY8 G;  3I55 E;  1M90 G;  3CCE E;  3CCL E;  3CCV E;  1YI2 E;  3CCS E;  1VQ6 E;  1YJW E;  3CCR E;  1RJL C;  1VQK E;  1P4P A;  2OY5 O;  1Q82 G;  1VQN E;  4IOA E;  1VQP E;  3CC4 E;  3DLL E;  2OL7 A;  2QA4 E;  5JVG E;  1K73 G;  1N8R G;  1VQ5 E;  1VQ9 E;  1JJ2 E;  2FKJ A;  3CKF A;  1YIT E;  2AF5 A;  2G8C O;  3CF5 E;  2OYB O;  5AN9 B;  4WFN E;  3CXC E;  2OTL E;  4IO9 E;  3J7Z G;  3G6E E;  1NJI G;  1QVG E;  3CCM E;  1OSP O;  5DM7 E;  1VQO E;  5JVH E;  2I5V O;  3G71 E;  1VQ4 E;  5MLC H;  3CD6 E;  1YIJ E;  1RL6 A;  3EC5 A;  2OY7 A; 
#chains in the Genus database with same CATH homology
 1W2B E;  3PIP E;  4U67 E;  4WCE E;  3CCU E;  1VQM E;  5HL7 E;  2ZJP E;  1Q81 G;  4IOC E;  3CCQ E;  2ZJR E;  1VQL E;  1VQ7 E;  2CQL A;  5DM6 E;  3G4S E;  2QEX E;  1Q86 G;  3CC2 E;  3CC7 E;  1Q7Y G;  1VQ8 E;  1S72 E;  2ZJQ E;  2OTJ E;  1KD1 G;  1K9M G;  5GAE G;  1KQS E;  3OW2 E;  3CMA E;  5H1S I;  4WFB E;  1K8A G;  4WF9 E;  1QVF E;  1KC8 G;  4WFA E;  1YHQ E;  1M1K G;  3CME E;  3I56 E;  3CCJ E;  3CPW E;  5GAG G;  5GAD G;  1YJN E;  1YJ9 E;  5GAH G;  3PIO E;  4UY8 G;  3I55 E;  1M90 G;  3CCE E;  3CCL E;  3CCV E;  1YI2 E;  3CCS E;  1VQ6 E;  1YJW E;  3CCR E;  1VQK E;  1Q82 G;  1VQN E;  4IOA E;  1VQP E;  3CC4 E;  3DLL E;  2QA4 E;  1K73 G;  5JVG E;  1N8R G;  1VQ5 E;  1VQ9 E;  1JJ2 E;  1YIT E;  3CF5 E;  5AN9 B;  4WFN E;  3CXC E;  2OTL E;  4IO9 E;  1NJI G;  3J7Z G;  3G6E E;  1QVG E;  3CCM E;  5DM7 E;  1VQO E;  5JVH E;  3G71 E;  1VQ4 E;  5MLC H;  3CD6 E;  1YIJ E;  1RL6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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